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At least 19 recordsLinked to original sources
PubMed1978

[Radiotherapy of blastomatous hemangiomas - under special consideration of 44 eyelid hemangiomas (author's transl)].

The propriety of blastomatous hemangiomas to show spontaneous regression is underlined. Under certain indications, above all in case of eyelid hemangiomas, a radiotherapy is indicated. The moment of manifestation lies within the first three months of life, and the female sex is affected two times more frequently. The head represents the predilection spot within the distribution scheme of hemangiomas. 44 patients with eyelid hemangiomas who had been treated between 1968 and 1972 by the described irradiation method had check-up appointments five years later. The therapeutical results were evaluated according to certain criteria. 95,5% of the blastomatous hemangiomas showed a very good or satisfactory regression. Only 4,5% did not present any satisfactory success. In an advanced age of the patients, the hemangiomas do not always respond favourably to radiotherapy. In case of a strictly executed indication and a faultless irradiation technique, irradiation damages can be avoided. Our results show that, with regard to the spontaneous regression of blastomatous hemangiomas, total doses of 1000 to 1500 rd are sufficient. Finally the authors cite the standpoints of radiotherapy concerning the treatment of blastomatous hemangiomas and give recommendations for dosage principles.

Age Factors↗
PubMed1979

Ultrastructural comparison of capillary and cavernous hemangiomas of the orbit.

Capillary and cavernous hemangiomas are often grouped together as if they were modulations of the same entity. To clarify this nosologic question, three capillary hemangiomas in children and four cavernous hemangiomas in adults were studied by transmission electron microscopy. The capillary hemangiomas consisted of two variably admixed zones, solid cellular zones and zones with open vascular lumens. However, both zones had similar organization. Each vascular unit was composed of endothelial cells and pericytes, which persisted in a tumor three years after its clinical appearance. Macrophages and degenerating cells were found in the interstitium and may be related to the clinical feature of partial spontaneous regression. The cavernous hemangiomas had much larger lumens, and wider and more heavily collagenized trabeculae. The vascular walls were created by multilaminar smooth muscle cells. Therefore, capillary hemangioma is completely different from cavernous hemangioma, which resembles a venous tumor.

Adult↗
PubMed1992

[Embolization of drainage veins used in sclerotherapy of hemangiomas].

To improve the result of sclerotherapy for hemangiomas, the drainage veins of hemangiomas were embolized by injecting 95% alcohol into the hemangioma cavities. Alcohol injected into the cavity had to drain away through the vein of hemangioma and result in damage of the endothelial cells, and thrombosis on the venous wall, then the drainage vein is embolized. With the result of embolization of the drainage vein, the sclerosant solution injected into the hemangioma cavity cannot flow off any more. The sclerosant solution got much time to bring drug action into play, so the curative effect was raised. 30 patients including 24 cavernous hemangiomas and 6 mixed hemangiomas were treated with this method. 15 cases were cured, 11 cases were effective and 4 cases were ineffective. The effective rate was 86.7%.

Adolescent↗
PubMed1975

Intramuscular hemangioma in the head and neck.

Intramuscular hemangioma is a distinct type of hemangioma occurring within skeletal muscle and making up less than one per cent of all hemangiomas. They occur most often in the trunk and extremities, perhaps beacuse of the larger muscle volume in thos areas. 13.5 per cent of intramuscular hemangiomas do occur in the head and neck region and for this reason they should be considered in the differential diagnosis of head and neck masses. The first case of an intramuscular hemangioma of the digastric muscle is presented and confirmed by electron microscopic sections. An interesting finding in this tumor is the proliferation of both endothelial cells and pericytes. Hemangiomas are classified according to vessel size; "large vessel" cavernous, "small vessel" capillary, and "mixed". Various etiologies and modalities of treatment are discussed, and total excision with ligation of the feeding vessels is advocated to prevent the high incidence of later recurrence.

Adult↗
PubMed1977

Regression of orbital hemangioma detected by echography.

Two infants had orbital cavernous hemangioma that showed impressive regression documented by ultrasound follow-up. In a 15-week-old infant the hemangioma regressed from a size of 11.49 mm to 5.36 mm in prominence during a six-month period. In a 9-month-old infant the mass regressed from 8.53 mm to 4.6 mm during a six-month period. These cases demonstrate that orbital cavernous hemangioma in infancy occasionally shows impressive regression. Furthermore, they illustrate the value of orbital ultrasonography in defining the natural history of orbital hemangioma. Similar follow-up studies in large numbers of infants with orbital hemangioma are needed to further our understanding of the natural history of this tumor.

Female↗
PubMed1977

Hemangioma thrombocytopenia syndrome. A case masquerading as an encephalocele.

The association of hemangioma and thrombocytopenia has been recognized since 1940. We cared for a newborn boy whose hemangioma resembled an occipital encephalocele. The true diagnosis was suspected only when his platelet count dropped to 3,000/cu mm with severe intestinal hemorrhage on the third day of life. The diagnosis was confirmed by arteriography. The hemangioma was excised surgically, and the platelet count returned quickly to normal. The baby has done well subsequently. When feasible, surgical excision of the platelet-trapping hemangioma is the treatment of choice in the hemangioma thrombocytopenia syndrome.

Diagnosis, Differential↗
PubMed1979

Hemangioma of the temporalis muscle: a case report and review of the literature.

Hemangiomas are the most common benign tumors of infancy and childhood. Most involve skin and subcutaneous tissues and are readily visible. Intramuscular hemangiomas are very uncommon, and rarely appear in the musculature of the head and neck. A 59-year-old woman who had had a lipoma excised from her left temporal region many years earlier underwent excision of a hemangioma of the left temporalis muscle. Intramuscular hemangiomas do not spontaneously involute and should be removed as soon as they are diagnosed, in order to obviate later destruction of the involved muscle and adjacent tissues. Preoperative embolization of the hemangioma may reduce intraoperative hemorrhaging.

Eyeglasses↗
PubMed1978

Corticosteroid treatment of cutaneous hemangiomas: how effective? A report on 24 children.

Twenty-four children with cutaneous hemangiomas were treated with corticosteroids. The indications for therapy included interference with important bodily functions by the hemangioma, thrombocytopenia related to the hemangioma, or serious cosmetic effects secondary to the hemangiomas. Five children had no improvement, twelve had possible improvement, five had probable improvement and two had definite improvement while on corticosteroids. One child had growth retardation as a complication of corticosteroids; this was reversed when the medication wa dicsontinued.

Body Height↗
PubMed1978

Cavernous hemangioma of the retina.

Cavernous hemangioma of the retina is recognized as a distinct clinical entity. Although neurocutaneous findings are sometimes associated with these retinal tumors, in most of the cases reported to date, systemic features have not been described. This report describes two patients with cavernous hemangioma of the retina. One had neurologic symptoms and signs that were highly suggestive of a hemangioma of the brain stem, and the other had major congenital cardiovascular anomalies. During a five-year interval, the second patient had spontaneous incomplete sclerosis of the retinal hemangioma.

Adult↗
PubMed1975

Contact radiotherapy of cutaneous hemangiomas: therapeutic effects and radiation sequelae in 818 patients.

The paper presents statistical data on the therapeutic effects and radiation sequelae following Chaoul contact therapy of 818 cutaneous hemangiomas treated between 1938 and 1952. 73.3% of all irradiated hemangiomas showed initial improvement but complete involution with an excellent cosmetic result was observed in only 50% of lesions 5 years after treatment. During the same period of time, more than one-third of all patients developed mild to moderate cutaneous radiation sequelae (hyper- or hypopigmentation and telangiectases, rarely atrophy). The high incidence of late radiation effects is probably relation to the high total doses administered in this series of patients, the very short intervals between treatments and the age of the patients. Other radiation radiation hazards are also discussed. Since large studies have proven conclusively that spontaneous involution occurs in 95% of hemangiomas after several years, indications for radiotherapy of hemangiomas are extremely limited.

Adult↗
PubMed1977

Refractive errors associated with hemangiomas of the eyelids and orbit in infancy.

Asymmetrical refractive errors, both astigmatic and myopic, were associated with infantile hemangiomas of the eyelids and orbit in 46% of 37 patients who had large lesions and upper eyelid involvement predisposing to the ammetropia. The axis of the astigmatic error related to the location of the eyelid hemangioma and correlated closely with keratometric measurements of corneal astigmatism. The refractive errors tended to be stable despite eventual resolution of the hemangiomas. Efforts to combat strabismic and refractive amblyopia were rewarding in many patients. A history of complete eyelid occlusion during part of the first year of life was associated with dense amblyopia and eccentric fixation in some patients, but in other patients this history was compatible with the eventual development of useful vision. Absence of an asymmetrical refractive error in patients with eyelid and orbital hemangiomas rendered the prognosis for vision good in involved eyes.

Astigmatism↗
PubMed1979

Renal hemangioma: cause of massive hematuria.

Renal hemangiomas are an unusual cause of renal hematuria. Although a preoperative diagnosis of renal hemangioma is not always possible, the diagnosis of this case of marked blood loss from a renal hemangioma was made angiographically. The clinical characteristics of hemangiomas, as well as the use of angiography in the investigation of hematuria, are discussed.

Adult↗
PubMed1975

Klippel-Trenaunay syndrome associated with urinary tract hemangiomas.

Genitourinary hemangiomas in 2 children with Klippel-Trenaunay syndrome are reported. The presence of cutaneous hemangiomas should alert urologists to the possibility of urinary tract hemangiomas inpatients with gross hematuria. Transurethral manipulation of bladder hemangiomas should be avoided because of the danger of excessive hemorrhage, the treatment of choice being partial cystectomy.

Adolescent↗
PubMed1976

Hemangiomas of the salivary glands.

Five salivary gland hemangiomas in adults are reported. The feasibility of preoperative diagnosis on clinical and radiologic grounds is emphasized. Adult hemangiomas are of the cavernous type and can be differentiated from infantile capillary hemangiomas clinically as well as histologically. Cavernous hemangiomas in the adult should be treated by surgical excision.

Adult↗
PubMed1975

Hemangioma-thrombocytopenia syndrome; a disseminated intravascular coagulopathy.

A patient who had multiple hemangiomas and for whom results of coagulation studies were consistent with hemangioma-thrombocytopenia (Kasabach-Merritt) syndrome and a microangiopathic hemolytic process was asymptomatic prior to surgical removal of a lipoma. Postoperatively, she developed bleeding secondary to a disseminated intravascular coagulopathy. Her bleeding was controlled by anticoagulation therapy. A review of the literature provides evidence suggesting that the hemangioma-thrombocytopenia syndrome is due to a disseminated intravascular coagulopathy initiated within the hemangioma. Surgical trauma may precipitate exacerbations of the coagulopathy in these patients and all unnecessary surgical procedures should be avoided.

Disseminated Intravascular Coagulation↗
PubMed1992

Corticosteroid treatment of extensive hemangiomas: analysis of 22 cases in children.

During the past 16 years, 22 Thai infants with extensive hemangiomas which impaired bodily functions and were life-threatening, especially in Kasabach-Merrit Syndrome have been treated. The incidence of female-to-male ratio was 8:3, all of the hemangiomas appeared between birth and 3 months of age. Among the 22 infants, 11 (50%) had hemangiomas on the head and the neck, and 2 had laryngeal hemangiomas. Two cases of Kasabach-Merrit Syndrome, located at the shoulder and the thigh, were complicated with severe bleeding, infection and congestive heart failure. Ocular impairment, malocclusion, and cutaneous distortion were the most important functional problems. Three cases were associated with other congenital anomalies: intracranial angioma, Dandy Walker Syndrome and Klippel-Trenauncy Syndrome. Prednisone (2-4 mg/kg/d) was used in all cases with other symptomatic treatment. Antiplatelet aggregating and antithrombotic drugs were useful in Kasabach-Merrit Syndrome. Definite response was noted in 72.72 per cent of the patients, doubtful response in 23.32 per cent, and no response in 4.54 per cent which was better than in other reports. There were no serious side-effects of the corticosteroid treatments reported in our careful students.

Child, Preschool↗
PubMed1978

A case of giant cavernous hemangioma of the liver complicated by intravascular coagulopathy.

A case of liver hemangioma complicated by intravascular coagulopathy is presented because of the rarity of the association. Hemangioma of the liver was suspected by palpation of the liver tumor, scintigraphy and x-ray examination, and confirmed by selective hepatic arteriography in combination with exploratory laparotomy. Intravascular coagulopathy was established by demonstrating secondary fibrinolysis and consumption of platelets and coagulation factors. Unconjugated hyperbilirubinemia due to micro-angiopathic hemolytic anemia was also present. The clinical course of the clotting abnormalities was basically a chronic one with an occasional acute or subacute defibrination process associated with further enlargement of the hepatic tumor. These provide sufficient evidence that the intravascular coagulopathy was closely related with the hemangioma in the liver. Neither ligation of a presumed nutritional artery of the hemangioma nor radiation therapy caused any demonstrable reduction in the tumor size.

Adult↗