[THE PHYSICIAN AS THE CAUSE OF DISEASE (IATROGENIC DISEASES)].
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Iatrogenic diseases are defined as illnesses due to diagnostic or therapeutic procedures. The authors explore the possibility of recording iatrogenic diseases by a physician self-monitoring system. The responsible physician himself records his/her patients' iatrogenic complications on hospital discharge, after which the authors examine retrospectively all charts of the patients involved and a random sample of patients not included. The results show that in one year 208 of 1618 patients were recorded as having an iatrogenic disease which was severe in 88. 7.1% of these cases were not confirmed retrospectively (false positives). On the other hand, about one third of iatrogenic illnesses were not recorded (false negatives), though these were less severe cases only. We calculated that 17% of our patients had iatrogenic diseases, 22% of these were predictable. About a third of the patients had iatrogenic disease before hospital admission, and these patients had more severe, and other, iatrogenic diseases than those who acquired them during hospitalization. Iatrogenic complications affect other organ systems than non-iatrogenic acquired diseases. On average, patients with iatrogenic diseases were 6 years older and hospitalized 10 days longer than other patients. Although not all cases may be recorded, we believe that physician self-monitoring is preferable to other systems for recording iatrogenic diseases, since it may have a direct teaching effect on those who cause the illness.
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We prospectively studied all patients admitted to a multidisciplinary intensive care unit to determine how many of their diseases were iatrogenic and, of these, what number were potentially avoidable. Of 325 patients admitted in the course of one year, 41 (12.6%) were hospitalized because of iatrogenic disease. Many of these patients had concomitant serious illnesses. Nevertheless, 19 patients (46.3%) were admitted with iatrogenic disease resulting from therapeutic or technical errors that were potentially avoidable. Iatrogenic disease was fatal in eight cases, life-threatening in 13, moderate in 20.
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PURPOSE: Data pertaining to iatrogenic diseases have been recorded over the last 25 years. Regarding the evolution of medical practice (general ageing, more and more powerful drugs and complex procedures), it is not known whether the incidence and the consequences of iatrogenic diseases have changed since their first evaluation. METHODS: To determine the admission rate to intensive care units for iatrogenic diseases, with the purpose of analyzing risk factors and consequences, and to compare our results with previous data recorded in 1979 (admission rate: 12.6%, mortality: 20%, preventable events: 47%), a 1-year retrospective study was conducted in an intensive care unit (ICU). RESULTS: During 1994, 68 (10.9%) out of 623 patients were admitted to the ICU for iatrogenic diseases (drugs: 41, medical acts: 12, surgical acts: 15). They were not different--in terms of severity, mortality, workload and length of stay in the ICU--from the other 555 patients hospitalized for other reasons. They were hospitalized on average for 472 days in the ICU, with a 13% fatality rate and a financial cost of US $688,470. Risk factors for iatrogenic diseases were the age and the number of prescribed drugs. The rate of preventable events was 51%. CONCLUSIONS: In this study, the occurrence of life-threatening iatrogenic diseases was a persistent and important purpose for admission to the ICU. Risk factors and consequences are still identical to those reported in 1979. Our results emphasize the persistence of the noxious impact of iatrogenic diseases on the quality and cost of medical care.
A year's survey of iatrogenic disease in general practice showed that one consultation in every 40 was the result of iatrogenic disease. Iatrogenic disease may affect the doctor/patient relationship, often leading the doctor to feel guilty or the patient to become aggressive.
Iatrogenic diseases are common in the elderly, particularly in the hospitalized patient. Adverse outcomes may be induced by poor communication with patients, inadequate history and examination, and inappropriate use of diagnostic resources. However, even when resources are used appropriately, adverse outcomes do occur, hence the price paid for sophisticated medical and surgical techniques. Medications offer a great potential for adverse reactions, and careful prescribing and knowledge of the pharmacokinetic changes that occur with aging, particularly impaired renal excretion of drugs, together with the use of the minimum number of drugs and maneuvers to improve compliance, can reduce this risk. Complications of surgery should be anticipated and promptly recognized and managed.
"Iatrogenic disease" may be a misnomer and would be better termed "syndyadogenic disease"--literally, a disease caused by two people working together. Most iatrogenic disease is a result of an unconscious coequal collusion between doctor and patient. Using the psychoanalytic concepts of transference and countertransference, three patterns of doctor-patient collusion are seen: the needy child-omnipotent parent posture, the Pollyanna posture and the persecutor-victim posture.
Iatrogenic disease is considered as an unintentional or occasionally inevitable damage to the patient which is caused by the medical personnel during the patient management or at examinations, diagnostic and therapeutic procedures. Iatrogenesis, being the reverse side of medicine, is an essential part of medical progress. Any therapeutic exposures, especially to invasive techniques, are prone to both positive and negative effects. The development of the physician's skill, cultural standard, refinement, continuing self-education and analysis of errors in line with governmental program to improve public health are to warrant iatrogenic disease control.
Iatrogenic diseases were studied on the material of 500 autopsies taken without selection of children who died in 1988-1989. Iatrogenic diseases were found in 185 cases (37%), most frequently at the age of 7-28 days (65.8% of all dead children), least frequently at the age up to 7 days (18.5%). Total number of iatrogenic diseases (270) exceeded the number of observations. Nosological structure is given: complications of reanimation and intensive therapy were most frequent (71.5% of all iatrogenesis), surgical iatrogenesis was 19.2%. Iatrogenic diseases were the only cause of death or an important factor in the death in 13.6% of all autopsies of children born alive.
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Medical expert qualification of iatrogenic disease is developed on the basis of insurance assessment of events (accident, realized risk, error) and classification of their causes according to the principle of the triad patient-medical professional-environment taking into account medical technology (diagnosis, treatment, rehabilitation, prophylaxis). Medical error is considered as an integral term and include inadequate (erroneous) professional thinking and/or action. Therefore, it is suggested to qualify a medical error either as a fallacy, or negligence, or omission. Medical-technological standards, apart from legitimacy, are necessary for realization of an expert activity.