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At least 19 recordsLinked to original sources
PubMed1998

[A case of corneal abscess with impetigo contagiosa].

Impetigo contagiosa often occurs on the face of children. Although the eyelid and conjunctiva are frequently affected, no corneal involvement has been reported in Japan. We encountered a case of impetigo contagiosa with corneal abscess. The patient, an 8-year-old boy, complained of pain and presented with corneal abscess and iritis in the right eye as well as eruptions in the inferior eyelid and around the anterior nostrils. He was diagnosed as having impetigo contagiosa with corneal abscess. Because the corneal abscess and eruptions occurred at the same time and coagulase-positive Staphylococcus with identical drug sensitivity was isolated from both lesions, we considered the corneal lesion as a part of the impetigo contagiosa. When impetigo contagiosa occurs around the eye, especially on the eyelids, a careful examination of the anterior segment of the eye is needed.

Abscess↗
PubMed2000

The antibacterial activity of tea in vitro and in vivo (in patients with impetigo contagiosa).

A total number of 104 patients with impetigo contagiosa was included in this study. They were 47 females (45.2%) and 57 males (54.8%). Their ages ranged from one month to 40 years with a median of 4 years. This study was divided into two parts: PART I (in vitro): Thirty-five patients were swabbed to determine the microbiology of impetigo contagiosa which included 33 isolates of pure S. aureus (94.3%) and 2 of a combination of S. aureus and Streptococcus pyogenes (5.7%). The antibacterial effect of tea liquor (lotion) against S. aureus proved very effective. Antibiotic sensitivity was done for all bacterial isolates of S. aureus. PART II (in vivo): The antibacterial effects of tea liquor and ointment were tested by treating 64 patients with impetigo contagiosa. Tea ointment was very effective with a cure rate of 81.3%. Forty patients were taken as controls and divided into two groups. The first one was given an ointment containing Framycetin and gramicidin (soframycin) with a cure rate of 72.2%; the other group was given oral cephalexin with a cure rate of 78.6%. To the best of our knowledge, this study was the first one which demonstrated the anti-bacterial action of crude tea in vivo, against impetigo contagiosa. Clinical data about impetigo are also included in this study.

Administration, Cutaneous↗
PubMed1988

[Efficacy of sultamicillin fine granules in pyoderma, particularly in impetigo contagiosa].

Sultamicillin fine granules were administered orally to 21 patients with impetigo contagiosa and 1 patient with erysipelas, and its clinical efficacy and safety were assessed. The dosage was 10-30 mg/kg daily. Clinical efficacies of impetigo contagiosa were "excellent" in 20 cases and "fair" in 1 case, with an overall efficacy rate of 95%. The result of treatment in erysipelas was "good". Out of 19 strains of Staphylococcus aureus isolated from foci, 17 strains had high beta-lactamase activities. In these 17 strains, sensitivity to the drug was 2-32-fold higher than to ampicillin, and in 14 out of these 17 strains 4-8-fold higher sensitivity was noted. As side effects, mild diarrhea was seen in 2 patients, but those recovered spontaneously in 3-4 days without particular treatment.

Administration, Oral↗
PubMed1975

Predisposing factors of the skin surface in persons with impetigo contagiosa.

The following report describes the results of biochemical and physiological examinations in 32 persons, who had suffered from impetigo contagiosa in the last 2 years, as well as 21 control persons of the same age and sex. The examination of the skin surface of the patient group, when compared with the corresponding control group, showed the following significant results: 1. an increase in the percentage of free cholesterol in skin surface lipids possibly as a result of an increased cell turnover in the epidermis, 2. a decrease in reducing substances as revealed by the ferricyanide and the phenolsulfuric acid methods in the so called water solubles, 3. a decrease in the alkali resistance of the skin possibly as a result of a decreased barrier function of the stratum corneum. It is most likely that these results indicate predisposing factors, localized in the epidermis, for impetigo contagiosa.

Adolescent↗
PubMed2006

Recurrent staphylococcal conjunctivitis associated with facial impetigo contagiosa.

PURPOSE: To report the uncommon occurrence of impetigo contagiosa in the setting of recurrent staphylococcal conjunctivitis. DESIGN: Interventional case report. METHODS: A 32-year-old patient had a recurrent painful red left eye and facial rash. Clinical examination revealed left bacterial conjunctivitis and facial bullous impetigo. Microbiology cultures were taken from the nose, conjunctiva, and facial lesions. RESULTS: Microbiologic cultures grew Staphylococcus aureus, and hematology findings demonstrated an elevated white cell count with neutrophilia. Complete resolution was achieved with topical chloramphenicol ointment and oral dicloxacillin. CONCLUSIONS: Although uncommon, bullous impetigo may be associated with recurrent staphylococcal conjunctivitis in adults. Recurrent infections may require nasal decolonization, systemic antibiotics, and antiseptic body wash.

Administration, Oral↗
PubMed1979

Impetigo contagiosa--etiology in Iraq.

Two hundred cases of impetigo contagiosa were studied bacteriologically. Along with the usual staphylococci and streptococci, gram-positive diplococci were isolated in pure cultures in thirty-seven cases. Ninety-six cases were submitted for sensitivity tests to several antibiotics; the results are discussed.

Child↗
PubMed1994

Hydrogen peroxide cream: an alternative to topical antibiotics in the treatment of impetigo contagiosa.

In total, 256 patients with bacteriologically verified impetigo contagiosa were included in three double-blind, parallel group, randomized, multi-centre trials, where the efficacy of hydrogen peroxide cream (Microcid) was compared with that of fusidic acid cream/gel (Fucidin). The trials were performed at 47 centres in three countries, Sweden, Germany and UK, and the results are compiled in the present report. During the course of the 3-week treatment period, 92 patients out of 128 (72%) in the Microcid group were classified as healed, compared to 105 patients out of 128 (82%) in the Fucidin group. This difference was not statistically significant. The reduction in composite sign severity score (the sum of the score for erythema, vesiculation/bullae, weeping and crusting divided by four) in each separate study was 73%, 78% and 84% in the Microcid group and 85%, 85% and 84% in the Fucidin group. No statistically significant differences were found in the separate studies or when compiling the studies in a meta-analysis. When the patients had been classified as healed, beta-haemolytic streptococci were eliminated in all patients treated with Microcid cream. Since treatment started before the result of the bacteriology was known, another 135 patients with negative skin culture were enrolled in the trials, i.e. 391 patients were included in the safety analysis. Out of these, 23 patients reported the occurrence of adverse events, mainly classified as mild. In conclusion, Microcid cream has been documented as a topical alternative to fusidic acid in the treatment of impetigo.

Administration, Cutaneous↗
PubMed1975

Epidemiological aspects of impetigo contagiosa in western Sweden.

200 patients with primary impetigo were studied. Staphylococcus aureus was the only organism isolated in 72.5%, beta-hemolytic streptococci, group A, in 10%, and both pathogens in 15%. 17 of the 50 streptococcal isolates were typed serologically; 11 of these belonged to potentially nephritogenic types. A majority of these cases had identical strains in the nose and throat. Hence, the primary source of skin streptococcal in this study may be the nasopharynx. Uncomplicated cases were treated with topical antibiotics, and oral antibiotics were added in 22 cases with extensive lesions, fever or a concurrent throat infection. None of the 200 patients developed acute glomerulonephritis and urinary analyses were normal at follow-up after 3 weeks.

Adolescent↗
PubMed1988

Impetigo contagiosa: a comparison of erythromycin and dicloxacillin therapy.

One hundred patients with impetigo were prospectively enrolled in a study to determine the current etiology and comparative therapeutic efficacy of two oral antimicrobial agents active against both group A beta-hemolytic streptococci (GABS) and Staphylococcus aureus. After obtaining a bacterial culture from a representative impetiginous lesion, the children were randomized to receive 10 days of either erythromycin (40 mg/kg/day) or dicloxacillin (25 mg/kg/day). S. aureus alone was isolated from 46 children, and in association with GABS from 25 children. GABS alone was isolated from nine patients. Of the 59 evaluable children with S. aureus isolates, 28 of 29 treated with erythromycin and 29 of 30 treated with dicloxacillin were cured or improved on follow-up examination. Thus, we conclude that erythromycin is the drug of choice for impetigo in our midwestern locale because of its high efficacy and relatively low cost.

Adolescent↗
PubMed1989

Impetigo contagiosa III. Comparative efficacy of oral erythromycin and topical mupirocin.

Ninety-seven patients with impetigo were prospectively enrolled in a study to determine the comparative efficacy of systemic and topical antibiotic therapy. After obtaining a bacterial culture from a representative lesion, the children were randomized to receive seven days of either oral erythromycin or topical mupirocin administered three times daily. Staphylococcus aureus alone was isolated from 51% and in association with group A beta-hemolytic streptococci (GABS) from 29%; GABS alone was isolated from 4% of patients. Of 48 children who received erythromycin, 43 (90%) were clinically improved or cured, and 11 of 17 were bacteriologically cured. Of 49 children who received mupirocin, 47 (96%) were clinically improved or cured, and 10 of 14 were bacteriologically cured. At three-week follow-up, clinical cure rates and number of secondary household cases of impetigo were equivalent in both treatment groups. Mupirocin appears to be a well-tolerated, albeit expensive, alternative to erythromycin for the treatment of impetigo.

Administration, Oral↗