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[Focal infection? Did you say focal infection ... focal infection and uveitis].

A chronic seat of infection more often than not situated in the E.N.T. area is responsible for remote pathological symptoms commonly called focal infection. The eye may be a target organ, where focal infection appears in the form of a uveitis. Four clinical observations are reported as demonstration. The transmission mechanism operates through an immune phenomenon from bacterial antigens which engender reactions of hypersensitivity. The E.N.T. specialist must be aware of these symptoms and seek a pharyngeal, sinusal or latent buccodental infection.

Adult↗

FOCAL infection.

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Focal Infection↗

[Focal infection].

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Focal Infection↗

[Focal infections].

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Focal Infection, Dental↗

[The role of focal infections in the pathogenesis of diseases].

Focal infections have a definite role in various infectious complications. They may cause local propagation, systemic infection (sepsis) and metastatic infections. In such complications eradication of focal infections may have a curative and/or preventive effect. Such a role of focal infections in diseases of immunopathological origin cannot be proven. In these disorders the persistence of focal infection is not necessarily required for the progression of the disease, and eradication of focal infection(s) has no curative effect. There are no sufficient evidence favouring a connection between dental, tonsillar, and urogenital focal infections and allergic or autoimmune diseases. We also lack evidence that eradication of focal infections, apart from rare instances, might influence the prognosis of such patients.

Autoimmune Diseases↗

Participation of autonomic nerve in tonsillar focal infection.

Participation of the autonomic nerve in tonsillar focal infection was investigated by measuring neurotransmitters, receptors and microvibration. In focal infection patients, the volume of norepinephrine in the tonsil increased significantly and the number of a-adrenergic receptors decreased. These findings suggest that the focally infected tonsil exhibits a high degree of sympathetic nerve activity. The ratio of N-type in microvibration decreased systematically, which indicates some imbalance or immaturity of the autonomic nervous system in focal infection patients. Based on this data, the production mechanism of tonsillar focal infection was speculated from the point of view of the autonomic nerve.

Autonomic Nervous System↗