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Intestinal polyps in the Nigerian African.

Intestinal polyps appear to be relatively rare in the African including Nigerians, South African Bantus, and Ugandans. Only 40 histologically confirmed cases were encountered over a period of ten years. Analysis of these cases reveals a preponderance (60%) of the non-neoplastic juvenile type of polyp. Neoplastic polyps were not encountered in any female patient. The mean ages of the patients are much lower than what has been observed in Caucasians inhabiting developed and industrialized countries. It is felt that there is probably a common or related aetiological agent for neoplastic intestinal polyps and carcinoma because the frequency of intestinal carcinoma appears to be relatively low in areas with a low frequency of neoplastic polyps.

Adolescent

Intestinal polyps in American negroes and Nigerian africans.

Forty Africans from Nigeria and 89 American negroes with colorectal polyps were analysed by age, sex and type of polyp. The Nigerians were much the younger group (mostly under 20 years of age, whereas most of the American negroes were over 50) and far fewer of their polyps were truly neoplastic (7.5% compared with 87% of the Americans). These differences may be partly due to the American negro population being older than the Nigerian, and partly to environmental factors like those previously postulated to account for the difference in colon cancer incidence between these populations.

Adolescent

[Juvenile colonic mucosal polyps in adults].

The histology of all intestinal polyps removed endoscopically during the last 30 months has been reviewed. Among the 90 patients with a total of 154 polyps, 3 cases of juvenile polyps were found. All three were male adults who were aged 29, 34, and 50 years. In two patients the lesion was solitary, while one had polyposis with about 100 polyps. Macroscopically the juvenile polyps cannot be distinguished from adenomatous polyps, but their histologic appearance is typical. They are considered to be hamartomas and have no tendency to become malignant. Thus, juvenile polyposis does not represent a precancerous lesion as adenomatous polyposis does, and must therefore be treated differently. Therapy consists of endoscopic removal of all polyps. In order to differentiate juvenile from adenomatous polyps with certainty, histological examination of at least one polyp is necessary. This differential diagnosis is the indispensable precondition for appropriate therapy.

Adenoma

Intestinal polyposis associated with oxyurid parasites in a chimpanzee (Pan troglodytes).

A 40-year-old male chimpanzee had multiple intestinal polyps associated with immature male oxyurid parasites. The gross and histologic characteristics of these lesions were identical to those produced by Nochtia nochti in the stomach and esophagus of Old World primates. It was theorized that the lesions resulted from hypersensitivity to oxyurid infection in an aberrant host.

Animals

Inflammatory pseudotumors (inflammatory fibrous polyps) of the small intestine: A clinicopathologic study.

The clinical and pathologic features of 25 inflammatory pseudotumors of the small intestine are reported. These rare lesions, which clinically may simulate neoplasms, consist of localized, frequently polypoid masses composed of inflamed fibrous and granulation tissue. Inflammatory pseudotumors may produce intussusception and small-bowel obstruction. Some are found at laparotomy performed for other reasons. The diagnosis of inflammatory pseudotumor usually can not be made until the lesion is examined histogically. Their etiology remains unknown, but their relationship to intestinal ulceration is discussed. Problems in differential histologic diagnosis are considered.

Adult