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Kenya: the development of private services and the role of the Kenya Veterinary Association.

Private veterinary practice has existed in Kenya for more than half a century. Between the early 1930s and the mid-1960s, provision of clinical and advisory services almost entirely involved servicing commercial ranches and dairy farms. The Department of Veterinary Services (VSD) was mainly responsible for providing regulatory services in these areas. Until the mid-1960s, public sector veterinary responsibilities were predominantly associated with the prevention of notifiable diseases outside the commercial farming areas. In a major agrarian reform programme initiated in 1954, Kenya initiated an aggressive campaign promoting the dairy industry in the wetter areas of the country among small-scale farmers. In an effort to encourage dairy development, the VSD decided to provide some services, mainly tick control and subsidised artificial insemination. This support had a great positive impact on the 'smallholder' dairy industry. After the end of the colonial administration in 1963, most private practitioners left the country. A decision was therefore taken to transfer the responsibility of providing services of a 'private goods' nature, such as clinical services, temporarily to the public sector through the VSD. This was accompanied by significant expansion of training and the deployment of both professional veterinarians and para-professionals. By 1988, personnel costs had escalated to over 80% of the recurrent budget, leaving little for operational costs. This necessitated a policy change, which led to decreased government involvement in the delivery of animal health services. The private sector, as expected, responded appropriately to the change in policy. The Kenya Veterinary Association (KVA) launched a privatisation scheme (the Kenya Veterinary Association Privatisation Scheme) in 1994 to provide members with credit to set up private practices. The first phase of the scheme (1994-1996) was rated a success, with 100% loan repayments. The second phase of the project (from 1997) was characterised by a low number of loan applications, which increased the cost of loan administration per unit. There was some defaulting in loan repayments during this phase. While private veterinary practice took root in the high rainfall, intensive farming areas, this was not the case in the arid and semi-arid lands (ASAL), where community-based animal health workers (CAHWs) played a prominent role in providing animal health services. The lack of uniformity in the training of these workers denied them recognition by the Kenya Veterinary Board (KVB). An agreement has now been reached between the KVB, the Director of Veterinary Services and the KVA to discontinue the training of CAHWs and to retain and retrain existing workers for disease surveillance and reporting in ASAL areas. In conclusion, private veterinary practice has been successful in areas of high agricultural potential. Expansion to more marginal areas, however, would require incentives or subsidies.

Animals↗

Blindness and eye disease in Kenya: ocular status survey results from the Kenya Rural Blindness Prevention Project.

A series of eight regional eye surveys were conducted in Kenya as part of the Kenya Rural Blindness Prevention Project. Each survey consisted of clinical examinations of about 1800 individuals selected by a random cluster sampling technique in geographically distinct and culturally homogeneous rural areas; 13,803 examinations were completed in all. Together these surveys provide the basis for national estimates of the prevalence and aetiology of visual loss and ocular pathology. The results showed that 0.7% of rural Kenyans are blind in the better eye by WHO standards, and another 2.5% suffer significant visual impairment. Rates of visual loss tend to increase five-fold in each 20-year age cohort. Females have higher prevalence of visual loss than males over age 20, and certain geographical areas have markedly higher rates. The commonest cause of both blindness and visual impairment is cataract, accounting for 38% of all visual loss. Trachoma (a localised problem), glaucoma, macular degeneration, and severe refractive errors follow cataract as leading causes of blindness in the better eye. Trauma, corneal scars of various causes, phthisis, and staphyloma are important causes of monocular blindness. Nutritional eye disease does not appear to be a problem of any magnitude in rural Kenya.

Adolescent↗

Microgeographic genetic differentiation of Anopheles gambiae mosquitoes from Asembo Bay, western Kenya: a comparison with Kilifi in coastal Kenya.

Microgeographic differentiation in Anopheles gambiae from seven villages less than 10 km apart in Asembo Bay, western Kenya was estimated by analysis of variability in seven microsatellite loci. Results from the Asembo Bay villages were compared with specimens collected in Kilifi, coastal Kenya, 700 km to the east. Allele frequency distribution was very similar in all villages in Asembo Bay, but differed for the Kilifi population. Genetic differentiation among villages was low with loci-specific Fst falling within the range of 0.0000-0.0085. These low estimates of differentiation correspond to among-village migration indices greater than 5.66, suggesting a high level of gene flow within the Asembo population. The Nm value between Kilifi and Asembo Bay was 1.54, indicating much lower levels of gene flow. Average observed heterozygosity among the seven villages was in all but one case less than the expected heterozygosity, most likely indicating the presence of null alleles, but possibly the presence of randomly mating units (demes) smaller than the village. We conclude that there is likely no genetic structure at the level of the village in Asembo Bay but that gene flow is restricted between western and coastal Kenya, probably by the high elevation rift.

Alleles↗

Microsatellite and mitochondrial genetic differentiation of Anopheles arabiensis (Diptera: Culicidae) from western Kenya, the Great Rift Valley, and coastal Kenya.

The population genetic structure of the African malaria vector Anopheles arabiensis from western Kenya, the Great Rift Valley, and coastal Kenya was investigated using 12 microsatellite loci and a partial sequence of mtDNA dehydrogenase gene subunit 5 (ND5). The mean number of alleles and the observed heterozygosity were similar for the mosquito populations from the three regions as revealed by the microsatellite data. A total of 30 polymorphic sites in the ND5 gene defined 39 haplotypes. Six haplotypes were shared among four populations from the three distinct ecological conditions, and they constituted 92% of the total number of individuals sequenced. Mitochondrial haplotype and nucleotide diversity were high. Microsatellite markers within polymorphic inversions revealed a level of genetic differentiation (F(ST) = 0.116) four to seven times higher than markers outside inversions (F(ST) = 0.016) or inside fixed inversions (F(ST) = 0.027). Mitochondrial ND5 gene sequences did not reveal significant genetic differentiation for the same four populations (phi(ST) = -0.008). The contrasts in the level of genetic differentiation between microsatellite markers inside polymorphic inversions, the mitochondrial ND5 gene, and microsatellite markers outside inversions suggest that the level of genetic differentiation in An. arabiensis populations across the Great Rift Valley varies significantly among different areas of the genome. Variations in the degree of genetic differentiation with respect to the chromosomal location of microsatellite markers may result from intrinsic characteristics of the markers, demographic or historic factors affecting these populations, and the possible adaptive significance of chromosomal inversions to climatic conditions.

Animals↗

Hydatid disease in the Turkana District of Kenya. III. The significance of wild animals in the transmission of Echinococcus granulosus, with particular reference to Turkana and Masailand in Kenya.

The results are given of a study on the role of wildlife in the transmission of Echinococcus granulosus in the Turkana and Narok Districts of Kenya. A total of 76 wild carnivores belonging to three separate species was examined from Turkana District. Echinococcus adults were found in 11 of 38 silver-backed jackals (Canis mesomelas) and in six of 22 golden jackals (Canis aureus). This is the first record of golden jackals being infected with this parasite in Kenya. None of 16 spotted hyaenas (Crocuta crocuta) harboured the parasite. Morphological features of the parasites obtained from the jackals were compared with material obtained from dogs in the same area. No morphological differences were recorded when this material was compared with data reported by others, hence the Turkana material belonged to the single species E. granulosus. Three silver-backed jackals and three puppies (Canis familiaris) were successfully infected with protoscolices obtained from a hydatid cyst surgically removed from a Turkana patient. Three spotted hyaenas fed the same material failed to become infected. None of 152 wild herbivores of five species examined in Turkana harboured hydatid cysts. The natural jackal infections in this District are thought to be incidental and dependent on the continuance of the domestic cycle. The role of the Turkana themselves in the perpetuation of the cycle is discussed. Twenty-six wild herbivores of six species were examined for hydatid cysts, in Narok District; hydatids were found in three wildebeest (Connochaetes taurinus) and a single topi (Damaliscus korrigum). The discovery of fertile cysts in wildebeest and the reported infections in lions (Panthera leo), Cape hunting dogs (Lycaon pictus) and silver-backed jackals, support previous evidence of the existence of a wildlife cycle in the Masailand and Serengeti regions of East Africa. The relationship of this cycle to the domestic cycle operating in the same area is unclear and requires further investigation.

Animals↗

[Seroepidemiological study of hepatitis B virus (HBV) infection in the rural community in Kenya--changing pattern of transmission model of HBV in Kenya].

The seroepidemiological study of HBV infection has been done against 9044 inhabitants in order to define a predominant transmission mode and a target population of HBV infection in Kenya. Results are as follows: 1) A total of 379 HBV carriers were identified. The prevalence of HBV carrier ranged from 4 to 9% in adults and 1 to 2% in children under 5 years of age. 2) The prevalences of HBs antigen and anti-HBc antibody in family members of carriers were 2 or 3 times higher than the other population. 3) 60 to 90% of the carrier children under 10 years old was positive for anti-HBe and 10 to 15% of the adult carrier and the pregnant carrier were found to be positive for e antigen. 4) Yearly infection ratio by horizontal route of transmission in the carrier family (1.4%) was 4 times higher than the control groups (0.3%). 5) 49% of the 96 carrier children was born to the carrier mother and in 40% the parent was negative for HBs antigen. 6) E antigen positive carrier mothers were highly infectious against their children than anti-HBe positive carrier mothers and fathers. These results suggest that HBV infection will happen more frequently within the family members of carriers either by horizontal and vertical infection. Marked reduction of carrier rate and infectivity observed in the children under 5 years of age infers that the improved way of mass immunization using disposable needles during infancy will deplete the incidence of horizontal mode of infection and that in the future mother to baby transmission appears to be the main route of HBV infection as in other developed countries.

Adolescent↗

Agents affecting health of mother and child in a rural area of Kenya. XI. Antibodies against rotavirus in sera from children living in the Machakos District of Kenya.

207 sera from children under 5 years of age and living in the Machakos District in Kenya were tested in the Complement Fixation Test for antibodies against rotavirus. Two different antigens were used. The superiority of 'O' antigen over Nebraska calf diarrhoea virus antigen was confirmed. After a fall to 29 percent in the 6-8 months age group, the percentage of children with antibodies quickly rises with age to 80 percent at the age of 24 months and to practically 100 percent at the age of 30 months. This age-immunity curve suggests that the majority of children contract infections with rotavirus between 6 and 23 months of age. This is conform the pattern usually found in temperate climate countries.

Antibodies, Viral↗

Epidemiology of leishmaniases in Kenya. Natural host preference of wild caught phlebotomine sandflies in Baringo District, Kenya.

Host preference of wild caught phlebotomine sandflies was studied in Marigat, Baringo District, Kenya, an endemic focus for both Leishmania donovani Laveran & Mensel and L. major Yakimov & Schokhov using precipitin test of blood meals. Sandflies of the Phlebotomus Rondani & Berte and Sergentomyia Franc & Parrot genera were encountered blood fed and resting in nine different habitats which were investigated. Analysis of their blood meals revealed a distinct host preference between the Phlebotomus and Sergentomyia genera. A distinction of host preference within species of each of the two genera was also observed. Furthermore, certain resting habitats from which the bloodfed sandflies were collected appeared to be favoured by specific sandfly species. It was observed that most of the wild hosts such as lizards and rodents except the hippopotamus, shared the same resting habitats with the sandflies. It was also observed that the man-biting sandflies preferred to rest outdoors after feeding. Domestic animals and man were the favoured hosts of vectors of both visceral and cutaneous leishmaniases, thus introducing an element of zooprophylaxis.

Animals↗

Machakos project studies agents affecting health of mother and child in a rural area of Kenya. XXIII bacterial contamination of foods commonly eaten by young children in Machakos, Kenya.

A simplified method, the Agar Immersion Plating and Contact (AIPC) slide technique was applied for the bacteriological examination of children's dishes and drinking water in Machakos District, Kenya. A total of 214 samples, collected from 106 households, were examined for degree of colonization by Enterobacteriaceae (E) and Staph. aureus (ST). Fourty four percent of the dishes and two percent of the water samples were unsafe with respect to Enterobacteriaceae. In 12% of the dishes and none of the water samples Staph. aureus occurred at levels above the threshold of acceptability. Colonization increased with storage time. Implications of these results in relation to diarrhoea morbidity patterns among young children are being investigated elsewhere.

Child, Preschool↗

Machakos Project Studies. Agents affecting health of mother and child in a rural area of Kenya. XX. A dynamic approach to the utilization of health services in a rural area of Machakos, Kenya.

Utilization of health services can be considered as a longitudinal process, in which individuals on having complaints make a choice between various health improving activities. This approach, employing a method described by Grundy and Reinke (1973) is used to analyse results of a survey on health services utilization in Machakos district, Kenya. Transition matrices for the population as a whole and for males, females and under-fives could be constructed. Differences in health improving behaviour between males and females, over- and underfives were found. Self medication and taking no action on a complaint were found to be important options for the study population. A distinct path through the health services by members of the population emerges. A indicator of effectiveness of different types of services is tentatively applied.

Adult↗

Agents affecting health of mother and child in a rural area of Kenya. X. Haemagglutination inhibiting antibodies against influenza A (H3N2) and influenza B virus in sera from children living in the Machakos District of Kenya.

In the framework of the Machakos Project bloodcollections from random samples of children under 5 years of age and living in a rural area of Kenya were done with regular intervals, Serum samples of two collections were tested for haemagglutination inhibiting antibodies against influenza A and B viruses. The children had been exposed to the Hong Kong/1/68 (H3N2) virus or its variants during one, two or three episodes of circulation and probably to only one epidosde of B/Hong Kong/8/73 virus. The results can be explained by the assumption that 30-40 percent of non-immune children were infected per epidosde of exposure to influenza A and not more than 12 percent per episode of influenza B circulation.

Antibodies, Viral↗

Aflatoxins and kwashiorkor in Kenya: a hospital based study in a rural area of Kenya.

Aflatoxin analyses were undertaken on sera and urines of 41 children admitted to a rural hospital in Kenya with kwashiorkor, marasmus, marasmic kwashiorkor or normal nutrition (Wellcome Classification). Aflatoxins were detected most frequently and at highest concentrations in the sera of kwashiorkors who, conversely, showed aflatoxins least frequently in their urine and in concentrations that were disproportionately low compared with serum/urine aflatoxin levels in other groups. These findings indicate altered aflatoxin metabolism in kwashiorkor and support the hypothesis that there are special relationships between aflatoxins and kwashiorkor.

Aflatoxins↗

Leishmaniasis in Kenya: description of leishmaniasis of a domestic goat from Transmara, Narok District, Kenya.

Extensive research has been carried out in Eastern Africa for animal reservoirs of both visceral and cutaneous leishmaniasis. The domestic dog has been the only domestic animal so far implicated as a possible reservoir for visceral leishmaniasis. For cutaneous leishmaniasis caused by Leishmania aethiopica, the hyrax and the giant rat are the proven reservoirs of the disease while several species of rodents have been demonstrated to harbor L. major. Recent studies conducted in domestic animals in West Pokot led to the first isolation of leishmanial parasites from a domestic goat, a close associate of man in the vast endemic leishmaniasis foci. Consequent encounter of a clinical case of the disease is the basis for this paper. It is the first autochthonous case in Eastern Africa. The goat originated from the Western escarpments of the Rift Valley which are known to harbor L. aethiopica. Clinical signs included lesions, indurations, and enlargement of lymph nodes. Parasitological and pathological investigations revealed amastigotes in various tissues. Cultures of the affected tissues produced promastigotes.

Animals↗