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Cervical kyphosis: predictive factors for progression of kyphosis and myelopathy.

STUDY DESIGN: A retrospective study of 13 patients with cervical kyphosis. The authors propose new methods of measuring spinal cord compression and predicting the progression of kyphosis. OBJECTIVES: To ascertain predictive factors for progression of cervical kyphosis and myelopathy. SUMMARY OF BACKGROUND DATA: Cervical kyphosis may be congenital, result from decompression surgery, or occur as a posttraumatic deformity. Although there is the potential for progressive deformity and the development of myelopathy in all these situations, there are few previous reports of predictive factors for progression of cervical kyphosis and myelopathy in patients with cervical kyphosis. METHODS: The authors studied radiographs and magnetic resonance imaging scans of 13 patients with cervical kyphosis, including 9 who had been operated on and had postsurgical secondary kyphosis, and 4 with idiopathic kyphosis without any of the above causes. Compression of the spinal cord at the apex of the cervical kyphosis was evaluated by magnetic resonance imaging of the ratio between the anteroposterior diameter of the medulla-pons junction and the spinal cord at the apex. RESULTS: The mean ratio between the anteroposterior diameter of the medulla-pons junction and the spinal cord at the apex in five patients in whom myelopathy did not develop was 0.37, and was 0.21 in the patients in whom myelopathy developed. Progression of cervical kyphosis was associated with osteophyte formation at the anterior aspect of the vertebral body. CONCLUSION: A ratio below 0.3 between the anteroposterior diameter of the medulla-pons junction and the spinal cord at the apex was a risk factor for cervical myelopathy. One of the most predictable risk factors of progression of the cervical kyphosis was osteophyte formation at the anterior aspect of the vertebral body.

Adolescent↗

The duPont kyphosis brace for the treatment of adolescent Scheuermann kyphosis.

The purpose of this study was to evaluate the effectiveness of a newly designed brace in the treatment of adolescent Scheuermann thoracic kyphosis. Twenty-two children who met the roentgenographic criteria of Scheuermann kyphosis and were compliant with treatment were followed until skeletal maturity. Sixteen patients (73%) showed nonprogression of their kyphosis (nine patients demonstrated an improvement, seven patients remained unchanged), and had a mean improvement of 9 degrees (64 degrees to 55 degrees). Six patients (27%) demonstrated progression of the kyphosis and had a mean increase in their kyphosis of 9 degrees (59 degrees to 68 degrees). One patient underwent posterior spinal fusion for progressive thoracic kyphosis despite bracing. It was recommended that this brace be worn until skeletal maturity; in this study this time period was determined to be at least 16 months to induce improvement or halt progression of this disease. Flexible curves are a positive predictor of a successful outcome of bracing with the kyphosis brace. These results are comparable to previous reports in the literature describing the effectiveness of the modified Milwaukee brace in the treatment of Scheuermann thoracic kyphosis prior to skeletal maturity, and the kyphosis brace has the advantage of concealability under normal attire.

Adolescent↗

Measurement of spinal kyphosis: implications for the management of Scheuermann's kyphosis.

STUDY DESIGN: Repeat clinical radiograph measurement of kyphosis was performed. OBJECTIVES: To evaluate precision in kyphosis measurement, the presence of intra- and interobserver error, and the effect of endplate selection and curve magnitude on error. SUMMARY OF BACKGROUND DATA: One study thus far has shown no interobserver difference in readings and an error interval of +/-11 degrees. METHODS: Four experienced examiners measured 30 radiographs of varying angles of kyphosis without preselected end vertebrae twice using the Cobb method. RESULTS: The mean intraobserver variance was 4.3 degrees (95% confidence interval, +/-9.6 degrees). One examiner had significantly better precision (P= 0.02) than the other examiners, who had no significant difference among them (P = 0.41). This examiner's mean intraobserver difference was 2.3 degrees (95% confidence limit, +/-6.2 degrees ). The 95% confidence limit for the interobserver difference was +/-8.7 degrees. The vertebral error index did not have a rank correlation with precision between readings. Magnitude of curve did not correlate with variance in measurement. CONCLUSIONS: The broad range in intra- and interobserver differences in the measurement of kyphosis should be taken into account in making management decisions or evaluating the success or failure of a treatment program. Careful technique in measurement may allow for improvement in individual precision.

Comorbidity↗

Proximal kyphosis after posterior spinal fusion in patients with idiopathic scoliosis.

STUDY DESIGN: For this retrospective study, preoperative and postoperative radiographs of posterior spinal fusions for idiopathic scoliosis were reviewed. OBJECTIVES: To determine the prevalence and possible causes of proximal kyphosis after posterior spinal fusion for idiopathic scoliosis. SUMMARY OF BACKGROUND DATA: Proximal kyphosis has been anecdotally noted after the insertion of Harrington rods and after use of the new posterior multisegmented hook/rod systems. In this study no attempt was made to determine whether this condition is painful or an adverse outcome for the patient or just a radiographic abnormality; however, it is suspected that this may be a problem in the long term, and it may be worthwhile to try to avoid it if predictive values can be ascertained. METHODS: Patients with adolescent idiopathic scoliosis who had undergone posterior spinal fusion not extending above T3 with good-quality radiographs of the proximal thoracic spine and a minimum 2-year follow-up were studied. Of the 106 patients who underwent posterior spinal fusion from 1990 through 1994, 69 met the inclusion criteria. Abnormal kyphosis from T2 to the proximal level of the instrumented fusion was defined as kyphosis of more than 5 degrees above the summed normal angular segments. RESULTS: Of 69 patients, 37 (54%) had normal proximal kyphosis, and 32 (46%) of the 69 were defined as having abnormal proximal kyphosis. In the 32 patients with abnormal proximal kyphosis, the measurement from T2 to the fusion was 10.3 degrees before surgery and 21.2 degrees after surgery. The normal group had kyphosis measuring 2.7 degrees from T2 to fusion before surgery and 5.3 degrees after surgery (P < 0.00001). Junctional kyphosis in the kyphosis group measured 6.5 degrees before surgery and 12.6 degrees after surgery, compared with normal kyphosis of 1.7 degrees and 2.6 degrees, respectively (P < 0.00001). When analyzing who would develop proximal kyphosis, preoperative one-level junctional kyphosis of more than 5 degrees above the proposed proximal instrumented vertebrae was shown to have the highest sensitivity (78%) and specificity (84%). CONCLUSIONS: In this study, 32 (46%) of 69 patients had abnormal proximal kyphosis after undergoing posterior spinal fusion. A preoperative junctional kyphosis of more than 5 degrees above the proposed proximal instrumented vertebrae indicates that extending the fusion to a higher level in the thoracic spine would be beneficial in avoiding this problem.

Adolescent↗

Correction of cervical kyphosis using pedicle screw fixation systems.

STUDY DESIGN: This retrospective study was conducted to analyze the clinical results in 30 patients with cervical kyphosis that had been treated using cervical pedicle screw fixation systems. OBJECTIVES: To evaluate the effectiveness of a pedicle screw fixation procedure in correction of cervical kyphosis. SUMMARY OF BACKGROUND DATA: Correction of cervical kyphosis is a challenging problem in the field of spinal surgery. There have been several reports regarding surgical correction of cervical kyphosis; however, there have been no detailed reports on correction of cervical kyphosis using a pedicle screw fixation procedure. METHODS: Thirty patients with cervical kyphosis underwent correction and fusion using cervical pedicle screw fixation. Seventeen of 30 patients with flexible kyphosis (Group I) were managed by a posterior procedure alone. The remaining 13 patients with rigid or fixed kyphosis (Group II) had a combined anterior and posterior procedure. RESULTS: The average preoperative cervical kyphosis of 29.4 degrees improved to 2.3 degrees after surgery and was 2.8 degrees at the final follow-up. In Group I patients, preoperative kyphosis of 28.4 degrees improved to 5.1 degrees at the final follow-up. In contrast, preoperative kyphosis of 30.8 degrees in Group II patients improved to 0.5 degree at the final follow-up. Solid fusion was achieved in all patients. There were two patients with transient nerve root complications related to pedicle screw instrumentation. CONCLUSION: Cervical kyphosis in 30 patients was effectively corrected using a pedicle screw fixation procedure with no serious complications. Flexible kyphosis with segmental motion can be satisfactorily corrected by a single posterior procedure using pedicle screw fixation. However, circumferential osteotomies combined with a posterior shortening procedure involving a pedicle screw system are required to achieve the best correction of fixed kyphosis by bony union. Cervical pedicle screw fixation is the most advantageous instrumentation in the correction of cervical kyphosis.

Bone Screws↗

Natural history of congenital kyphosis and kyphoscoliosis. A study of one hundred and twelve patients.

BACKGROUND: Congenital kyphosis and kyphoscoliosis are much less common than congenital scoliosis. However, they are potentially more serious because compression of the spinal cord and paraplegia sometimes develop. The goals of the present study were to document the natural history of congenital kyphosis and kyphoscoliosis and to determine the stage at which the natural progression should be interrupted by treatment. METHODS: We reviewed the medical records and radiographs of the spine of 112 consecutive patients. Sixty-eight patients had a type-I kyphosis due to an anterior failure of vertebral-body formation, twenty-four had a type-II kyphosis due to an anterior failure of vertebral-body segmentation, and twelve had a type-III kyphosis due to a combination of anomalies; the deformities of the remaining eight patients could not be classified. Eighty-five skeletally immature, untreated patients were first evaluated at a mean age of six years and nine months (range, two months to sixteen years and three months), and twenty-seven patients were skeletally mature at the time of the first visit. Sixty-three of the eighty-five skeletally immature patients were observed without any treatment for a mean period of six years and six months (range, one to sixteen years) before skeletal maturity, and the remaining twenty-two patients had a posterior arthrodesis of the spine soon after the initial visit. At skeletal maturity, forty-one patients had not been treated and sixty-eight had had an arthrodesis of the spine. The remaining three patients had not yet reached skeletal maturity at the time of the most recent follow-up. RESULTS: The apex of the kyphosis was seen at all levels but was most frequent between the tenth thoracic and the first lumbar level (seventy-four patients; 66 percent). There was no relationship between the severity of the kyphosis and its location in the spine. Progression of the curve was most rapid during the adolescent growth spurt and stopped only at skeletal maturity. Progression was most rapid and the magnitude of the curve was the greatest in type-III kyphosis (twelve patients) followed by type-I kyphosis due to a posterolateral quadrant vertebra (thirty-nine patients), a posterior hemivertebra (eight patients), a butterfly vertebra (fifteen patients), and a wedged vertebra (six patients). A kyphosis due to two adjacent type-I vertebral anomalies progressed more rapidly and produced a more severe deformity than did a similar single anomaly. The prognosis for type-II kyphosis was variable and was much more severe when an anterolateral unsegmented bar had produced a kyphoscoliosis (nine patients) than it was when a midline anterior bar had produced a pure kyphosis (fifteen patients), which usually progressed slowly. Spontaneous neurological deterioration due to compression of the spinal cord occurred in ten patients (seven of whom had a type-I kyphosis and three of whom had an unclassifiable anomaly) at a mean age of thirteen years and eight months, and one other patient (with an unclassifiable anomaly) had spastic paraparesis at the age of twenty-eight years. CONCLUSIONS: Congenital kyphosis and kyphoscoliosis are uncommon deformities with the potential to progress rapidly, resulting in severe deformity and possible neurological deficits. A thorough knowledge of the natural history is essential in the planning of appropriate and timely treatment to prevent progression of the deformity and neurological complications.

Adolescent↗

Management of rigid post-traumatic kyphosis.

STUDY DESIGN: Rigid post-traumatic kyphosis after fracture of the thoracolumbar and lumbar spine represents a failure of initial management of the injury. Kyphosis moves the center of gravity anterior. The kyphosis and instability may result in pain, deformity, and increased neurologic deficits. Management for symptomatic post-traumatic kyphosis always has presented a challenge to orthopedic surgeons. OBJECTIVES: To evaluate the surgical results of one stage posterior correction for rigid symptomatic post-traumatic kyphosis of the thoracolumbar and lumbar spine. SUMMARY OF BACKGROUND DATA: The management for post-traumatic kyphosis remains controversial. Anterior, posterior, or combined anterior and posterior procedures have been advocated by different authors and show various degrees of success. METHODS: One vertebra immediately above and below the level of the deformity was instrumented posteriorly by a transpedicular system (internal fixator AO). Posterior decompression was performed by excision of the spinal process and bilateral laminectomy. With the deformed vertebra through the pedicle, the vertebral body carefully is removed around the pedicle level, approximating a wedge shape. The extent to which the deformed vertebral body should be removed is determined by the attempted correction. Correction of the deformity is achieved by manipulation of the operating table and compression of the adjacent Schanz screws above and below the lesion. RESULTS: Thirteen patients with post-traumatic kyphosis with symptoms of fatigue and pain caused by slow progression of kyphotic deformities received posterior decompression, correction, and stabilization as a definitive treatment. The precorrection kyphosis ranged from 30-60 degrees, with a mean of 40 degrees +/- 10.8 degrees. After correction, kyphosis was reduced to an average of 1.5 degrees +/- 3.8 degrees, with a range from -5 degrees to 5 degrees. The average angle of correction was 38.8 degrees +/- 10.4 degrees, with a range from 25 degrees to 60 degrees. Significant difference was found between pre- and post-operative kyphosis measures (P < 0.001). The follow-up period for all patients was 2 years, and the average kyphosis angle measured at the moment was 3.8 degrees +/- 3 degrees with a range from -3 degrees to 8 degrees. Substantial overall improvement was achieved in the 13 patients. CONCLUSION: This method provides single-stage posterior decompression, correction, and stabilization on as definitive management for post traumatic kyphosis of the thoracolumbar and lumbar spine.

Adult↗

Cervical kyphosis in diastrophic dysplasia.

STUDY DESIGN: An evaluation of cervical kyphosis in diastrophic dysplasia from newborn to adult life. OBJECTIVES: To discover the prevalence and natural history of cervical kyphosis in diastrophic dysplasia. SUMMARY OF BACKGROUND DATA: Typical findings in this rare skeletal dysplasia are sport-limbed short stature, multiple joint contractures, early degeneration of joints, and spinal deformities such as cervical kyphosis, scoliosis, and exaggerated lumbar lordosis. In diastrophic dysplasia, spontaneous resolution of cervical kyphosis has been reported, but so have severe forms causing medullar compression leading to quadriplegia and death. The prevalence and clinical outcome of the kyphosis are not known. METHODS: The radiographic natural history of the cervical spine was studied in 120 patients. They varied in age from newborns to 63-year-olds. The average follow-up time in 26 living patients with cervical kyphosis was 10.0 years. RESULTS: Midcervical kyphosis was noted in 29 patients (24%) in their first radiograph. In 25 patients, the first radiographs were taken before the age of 18 months, and 24 of these patients (96%) had cervical kyphosis. The most severe case was that of a 32-year-old patient with a 165 degrees kyphosis. In the 24 patients, the kyphosis resolved spontaneously at an average age of 7.1 years. Three patients with a severe kyphosis died; one patient is alive. One patient, a 4-year-old child has mild resolving deformity. CONCLUSIONS: Cervical kyphosis in diastrophic dysplasia usually is shown at the time of birth. It resolves spontaneously during growth and seldom needs treatment. Careful follow-up study and treatment, if necessary, are important tools for avoiding the neurologic problems and fatal outcome.

Adolescent↗

Indications for surgery in so-called "regular" thoracic and thoracolumbar kyphosis.

Idiopathic thoracic, thoracolumbar, and Scheuermann's kyphosis do not figure in the same global entity. We propose a classification for so-called "regular" kyphosis. This classification is based on the location of the most rigid curvature segment. Segmental kyphosis may be short, in which case we can distinguish between four types: high kyphosis (type I), middle kyphosis (type II), low or thoracolumbar kyphosis (type III), and segmental kyphosis, which can extend along the entire thoracic spine (type IV). The symptomatology and therapeutic indications are different for each type. We report a series of 15 patients (6 female, 9 male), aged between 18 and 33 years (average age 24 years). The mean kyphosis angle (Cobb angle) in type I patients (n = 3) was 75 degrees in type II patients (n = 3) it was 82 degrees, and in type III patients (n = 9) it was 78 degrees. The pain was greater in type III patients. All patients were operated on using a double approach. As the first step, we performed an anterior approach, disc excision, and bone graft. Ten days later, a posterior approach with CD instrumentation was carried out on ten levels. The mean follow-up is 4 years (range 9 months in 7 years). We noticed no neurological complications and one case of late sepsis. Mean angular loss of correction was 6 degrees. The correction obtained depended on the type of kyphosis. We obtained a mean postoperative Cobb angle of 63 degrees in type I curves, 55 degrees in type II, and 45 degrees in type III. The new classification allows a better understanding of regular kyphosis and helps to define clinical and therapeutic approaches. An analysis of the resulting surgical correction can also be made by comparing homogeneous groups of patients.

Adolescent↗

Clinical outcome and radiographic results after surgical treatment of post-traumatic thoracolumbar kyphosis following simple type A fractures.

The surgical management of post-traumatic thoracolumbar kyphosis remains controversial. The need for combined procedures is subject to debate, especially for post-traumatic kyphosis after simple type A fractures. The aim of this retrospective study was to evaluate radiographic findings, patient satisfaction and clinical outcome after mono-segmental surgical treatment using an anterior procedure alone (group 1, n = 10 patients) and using a one-stage combined anterior and posterior procedure (group 2, n = 15 patients) for post-traumatic thoracolumbar kyphosis after simple type A fractures. The main indication for surgery was pain. There were no statistically significant differences between the patients in the two groups concerning age, cause of injury, time interval between trauma and surgery, preoperative kyphosis and preoperative back pain score. For all these 25 patients, complete follow-up data were available for retrospective evaluation. The median follow-up was 17 years in group 1 and 8 years in group 2. Radiographic documentation and classification was made on the basis of standing antero-posterior and lateral views and computed tomographic scans. Fractures were categorized according to the Magerl classification. Kyphotic deformity was assessed on lateral radiographs using the Cobb method. Kyphosis angles were measured preoperatively, directly postoperatively, and at final follow-up. For clinical evaluation, the back pain scoring system of Greenough and Fraser was used. Patients were requested to score their status prior to trauma, preoperatively and at follow-up. The Wilcoxon test was used for statistical analysis ( P < 0.05 is significant). In all cases radiographic union was achieved. Median kyphosis in group 1 was corrected from 23 degrees preoperatively to 12 degrees postoperatively ( P < 0.01) and was 11 degrees at follow-up. Median kyphosis in group 2 was corrected from 21 degrees pre-operatively to 12 degrees postoperatively ( P < 0.01) and was 12 degrees at follow-up. The median back score in group 1 changed from 66 points before the trauma to 23 points ( P < 0.01) preoperatively and 35 points at follow-up ( P < 0.01). The median back score in group 2 changed from 67 points before the trauma to 20 points ( P < 0.01) preoperatively and 38 points at follow-up ( P < 0.01). In group 2, four patients had complaints due to annoying prominence of the dorsal instrumentation. In all these cases the dorsal instrumentation was removed. Statistical analysis in this series of ten patients with anterior spondylodesis compared with 15 patients with combined one-stage spondylodesis did not reveal objective advantages of the combined procedure as far as the outcome of radiographic correction of kyphosis or patient outcome is concerned. It is therefore concluded that in cases of post-traumatic thoracolumbar kyphosis after simple type A fractures, mono-segmental correction using an anterior procedure alone, with spondylodesis, is the surgical procedure of choice.

Adolescent↗

Posterior instrumentation and anterior interbody fusion for tuberculous kyphosis of dorsal and lumbar spines.

STUDY DESIGN: Thirty-nine adults and five children with active spinal tuberculosis and resulting kyphosis of the dorsal and lumbar spine who had combined posterior instrumentation and anterior interbody fusion were observed to determine whether the corrected spinal deformity could be maintained until solid fusion. OBJECTIVE: To evaluate the effectiveness of the combined two-stage procedure for treating kyphosis due to active spinal tuberculosis. SUMMARY OF BACKGROUND DATA: Until 1970, with all methods of treatment, kyphosis due to active spinal tuberculosis tended to increase during therapy. Most of the patients treated with these methods were not happy with this residual kyphosis, even though their disease was arrested or cured. Kyphosis became their main concern regarding further treatment. METHODS: A combined two-stage procedure, under the cover of 18 months of triple chemotherapy, was used for all patients. For posterior stabilization, the Harrington distraction system, Rush nails or Steinmann pins and wires, and Texas Scottish Rite Hospital instrumentation were used. The diagnosis of successful interbody fusion was made if there was no loss of correction, no graft resorption or graft bed resorption, and if there was visible graft remodeling, such as trabeculation between the graft beds and graft and the graft hypertrophy. RESULTS: In the 39 adults, average preoperative, immediate postoperative, and last follow-up kyphosis angles were 37 degrees, 16 degrees, and 18 degrees, respectively. In four children, the average preoperative, immediate postoperative, and last follow-up kyphosis angles were 55 degrees, 28 degrees, and 31 degrees, respectively. The loss of correction did not exceed 3 degrees. For one-segment spondylodesis, the average fusion times were 4 months in adults and 3.5 months in children. For a two-segment fusion, the average fusion times were 6 months in adults and 6.3 months in children. CONCLUSION: Posterior instrumental stabilization and anterior interbody fusion were found helpful in arresting the disease early, providing early fusion, preventing progression of kyphosis, and correcting the kyphosis.

Adolescent↗

The surgical management of congenital kyphosis and kyphoscoliosis.

STUDY DESIGN: A retrospective study of surgery for congenital kyphosis and kyphoscoliosis. OBJECTIVE: To assess the effectiveness of different types of spine surgery in the management of congenital kyphosis and kyphoscoliosis. SUMMARY OF BACKGROUND DATA: Congenital kyphosis and kyphoscoliosis are much less common than congenital scoliosis but potentially more serious, because these curves can progress rapidly and Type I deformities can lead to spinal cord compression and paraplegia. No one operative procedure can be applied to all types and sizes of deformity. The method of surgical treatment depends on the age of the patient, the type and size of the deformity, and the presence or absence of spinal cord compression causing a neurologic deficit. METHODS: Sixty-five patients with a congenital kyphosis (n = 14) or kyphoscoliosis (n = 51) were treated by five different methods of spine arthrodesis: prophylactic posterior arthrodesis before age of 5 years (n = 11), posterior arthrodesis after age 5 years without instrumentation (n = 26) and with instrumentation (n = 12), combined anterior and posterior arthrodesis without instrumentation (n = 7) and with instrumentation (n = 9). Six patients had preoperative lower limb spastic paraparesis caused by spinal cord compression. The mean age at surgery was 9 years 6 months (range, 11 months to 25 years), and all 65 patients were observed for a minimum of 2 years (mean 6 years 6 months, range 2 to 18 years). Fifty-seven patients reached skeletal maturity. RESULTS: A posterior arthrodesis performed before the age of 5 years resulted in a gradual reduction of the kyphosis by a mean 15 degrees in 9 of the 11 patients, followed up for a mean of 11 years, whose initial kyphosis was less than 55 degrees. Patients treated after the age of 5 years by a posterior arthrodesis followed by cast application had poor correction and a high incidence of pseudarthrosis. This was not significantly improved by the addition of posterior instrumentation. For curves greater than 60 degrees, the most successful results were achieved by an anterior spinal release and arthrodesis with strut graft correction followed by posterior arthrodesis with instrumentation (if possible). CONCLUSION: All patients with a Type I or Type III congenital kyphosis or kyphoscoliosis should be treated by a posterior arthrodesis before the age of 5 years and before the kyphosis exceeds 50 degrees. A kyphosis that does not reduce to less than 50 degrees as measured on the lateral spine radiograph made with the patient supine requires an anterior release and arthrodesis with strut grafting followed by posterior arthrodesis with instrumentation (if possible).

Adolescent↗

Nonsurgical treatment of kyphosis.

An increase in thoracic kyphosis in children and adolescents is usually the result of postural kyphosis or Scheuermann's kyphosis. Although no structural deformity of the spine is observed in postural kyphosis, wedging of vertebral bodies and disk space narrowing are noted radiographically in patients with Scheuermann's kyphosis. Effective interventions for adolescents with postural kyphosis include exercises to relieve lower extremity contractures and strengthen abdominal musculature coupled with practiced normal posture in stance and in sitting. Skeletally immature patients with Scheuermann's kyphosis benefit from a similar exercise program but also require the use of a spinal orthosis. Bracing of the spine in patients with Scheuermann's kyphosis results in permanent correction of vertebral deformity, unlike bracing in patients with idiopathic scoliosis. The evaluation of children and adolescents with increased thoracic kyphosis is an important aspect of the decision process used to determine appropriate interventions.

Adolescent↗

Single stage decompression, anterior interbody fusion and posterior instrumentation for tuberculous kyphosis of the dorso-lumbar spine.

STUDY DESIGN: To evaluate the role of single stage decompression with anterior interbody fusion with posterior instrumentation and deformity correction of tuberculous kyphosis of the dorso-lumbar spine in patients with/without neurological deficit. OBJECTIVES: (1) To evaluate the amount of kyphosis correction with single stage surgery and its progression with time. (2) To evaluate the neurological recovery. (3) To evaluate the bony anterior interbody fusion. SETTING: King Edward Memorial Hospital, Bombay, India. METHODS: Twenty-eight patients with post-tuberculous kyphosis deformity averaging 64.3 degrees (range 17 to 105) were treated by a single stage posterolateral decompression, correction of kyphosis, anterior interbody fusion and posterior instrumentation. RESULTS: The mean kyphosis correction obtained was 62.5% with the mean post-operative kyphosis angle reducing to 24.1 (range 5-60). At a mean follow-up of 5.8 years (4-7 years) the mean kyphosis angle loss was 3.2 degrees (range 0-5 degrees ). Of the 23 patients with neurological deficit, recovery was seen in 21 cases (91.3%) while deterioration was seen in one case (4.3%). The remaining five patients were neurologically intact pre-operatively. Bony fusion was seen in all cases at 9 months. One patient with subpulmonary function died post-operatively (mortality 3.5%). CONCLUSION: The results of our series are encouraging. However single stage decompression with fusion and kyphosis correction is a very demanding surgery and should be performed after taking into account the risks and benefits involved. This surgery perhaps prevents progression of neurological deficit and recurrence of late onset paraplegia in these complex cases in developing countries.

Adolescent↗

Prediction of thoracic kyphosis using the Debrunner kyphometer.

The Debrunner kyphometer is an accepted tool for detecting and evaluating thoracic kyphosis. This prospective study was conducted to create a mathematical formula that provides, with high approximation, the roentgenographic angle of thoracic kyphosis (T4-T12) using only the kyphometer. Several clinical (kyphometer value, age, and sex) and radiographic (Cobb angle [T4-T12]) parameters from 90 consecutively screened adolescents (44 male and 46 female) were correlated using simple and multiple linear regression analyses. The reliability of measurement using the Debrunner kyphometer was high. The kyphometer value was strongly correlated with the roentgenographically measured thoracic Cobb angle (simple linear regression analysis; probability range, 0.0026 to 0.0002). There was no correlation between age or sex and thoracic kyphosis. The predicted kyphosis angle using the kyphometer and the mathematic formula was 44.66 degrees +/- 2.68 degrees, (range 27 to 62 degrees), and the real roentgenographic kyphosis angle was 47.5 degrees +/- 3.53 degrees, (range, 24 to 70 degrees). The kyphometer and formula were more reliable and accurate when kyphosis less than 50 degrees was measured. In this study, the authors constructed a mathematical formula that accurately provides the roentgenographic T4-T12 kyphosis angle in adolescents using only the Debrunner kyphometer with a deviation of less than 3 degrees. The authors recommend that all physicians engaged in kyphosis screening programs use the kyphometer combined with the recently constructed simple mathematic formula. This method will reduce the cost of school screening programs, overdiagnoses, and unnecessary exposure of adolescents to irradiation.

Adolescent↗

Kyphosis in active and sedentary postmenopausal women.

UNLABELLED: EAGAN, M. S., and D. A. SEDLOCK. Kyphosis in active and sedentary postmenopausal women. Med. Sci. Sports Exerc., Vol. 33, No. 5, 2001, pp. 688-695. PURPOSE: This study examined kyphosis in relation to self-reported activity level (sedentary, active) and activity type (weight-bearing land, nonweight-bearing water) in 61 postmenopausal women aged 60-78 yr. METHODS: Specifically, we measured kyphosis, muscle strength (defined as back extensor (BES) and grip (GS) strength), total calcium intake, body fat, height lost since age 30 (HtLost), current activity level for household, leisure and sport activities and their total, as well as occupational and physical activity history and their total. RESULTS: No significant differences (P > 0.05) were found for any variables when subjects were divided into sedentary (N = 18), land (N = 29), and water (N = 14) groups; exercisers (N = 43) and nonexercisers (N = 18); or between the top and bottom tertiles of lifetime active (N = 20) and inactive (N = 20) women. Stepwise multiple regression yielded body fat as the single best predictor of kyphosis accounting for 6.9% of the total variance (P < 0.04) with the resulting equation: kyphosis (degrees) = 22.919 + 0.627*body fat (%) + 0.852*HtLost (cm) + 2.881E-0.03*total calcium intake (mg) (r2 = 0.22, SEE = 7.7). Significant relationships (P < 0.05) included kyphosis with body fat (r = 0.26) and HtLost with age (r = 0.50). Relationships (P < 0.05) regarding muscle strength included: GS and BES with age (r = -0.38, -0.30), HtLost (r = -0.39, -0.36), and occupational activity history (r = 0.28, 0.35), as well as BES with household activity and total activity history (r = 0.28, 0.30). Physical activity history was related (P < 0.05) to current sport, leisure, and total activity history (r = 0.37, 0.42, 0.93, respectively). CONCLUSION: Women who are active when younger seem to be active and stronger as older adults. However, this does not seem to impact kyphosis. The measured variables accounted for a small proportion of kyphosis variance, suggesting that more potent causative factors of this spinal malformation exist.

Activities of Daily Living↗

Interrater and intrarater reliability in the measurement of kyphosis in postmenopausal women with osteoporosis.

STUDY DESIGN: A reliability study was performed using repeated random measurements involving three observers, 26 subjects and three instruments. OBJECTIVES: To determine the most reliable, cost-effective, noninvasive, and clinically feasible method of measuring spinal kyphosis. SUMMARY OF BACKGROUND DATA: The most clinically useful, noninvasive and reliable method of measuring postural deformity in spinal osteoporosis (kyphosis) remains unqualified. Despite traditional use of costly, invasive roentgenographs for the evaluation of spinal kyphosis, the reliability of this method remains questionable. METHODS: Twenty-six postmenopausal women with known bone mineral density and a diagnosis of osteoporosis were recruited from the Osteoporosis Program at Women's College Hospital, Toronto, Canada. Non-invasive measurements of thoracic kyphosis were obtained by three trained examiners using the DeBrunner's kyphometer and the flexicurve ruler. The intrarater and interrater reliability of and between each method was compared, using roentgenographic films obtained in the sagittal plane. Spinal posture was classified according to the method of Itoi (1990). Statistical computations were performed using SAS statistical software. RESULTS: Consistent measurements were obtained with the DeBrunner's kyphometer and the flexicurve ruler by each observer, according to the results of critical two-way analysis of variance (Intraclass Correlation Coefficient 2, 1). Measurements in two subgroups, healthy backs (n = 11) and rounded backs (n = 13), showed consistent use of each noninvasive instrument with some examiner preference for specific tools. There was marginally better intrarater and interrater reliability using the DeBrunner's kyphometer compared with that obtained with the flexicurve ruler. Two-way analysis of variance (Intraclass Correlation Coefficient 2, 1) of collapsed data showed no significant difference in the reliability of the kyphometer, flexicurve ruler, or roentgenographs in the measurement of thoracic kyphosis. CONCLUSIONS: The flexicurve ruler and DeBrunner's kyphometer had the closest agreement in the measurement of spinal kyphosis. The kyphometer demonstrated the least variation in intrarater and interrater reliability when compared with the flexicurve ruler and roentgenographs. The flexicurve ruler permits qualitative assessment of posture, however, and is the most cost-effective instrument. The results of this study challenge the traditional belief that roentgenographic analysis is the best method for evaluating spinal kyphosis. The DeBrunner's kyphometer and flexible ruler may represent viable, cost-effective and noninvasive alternatives to roentgenographic evaluation of spinal kyphosis.

Aged↗