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[Acute kidney failure due to kidney cortex necrosis. 2 clinical cases of surviving patients].

A 22 year old female developed preeclampsia with fetal death in utero. After cesarean section she developed uterine inertia and acute hemorrhagic anemia complicated by sepsis, disseminated intravascular coagulation and total anuria for 4 weeks. She was treated with hemodialysis. The second patient, a 49 year old man developed sepsis and intravascular coagulation after a dog bite. Acute renal failure with a 3 week total anuria followed. He was initially treated with peritoneo dialysis. Renal biopsy showed evidence of renal cortical necrosis in both patients.

Acute Kidney Injury

[Prevention of testosterone-vasopressin induced necrosis of the kidney cortex by cyproterone acetate].

After a ten days pretreatment with testosteron-propyonate administration of vasopressin induces bilateral cortical necrosis of kidneys in rats. When testosteron and cyproteron-acetate an androgen-blocking agent were given simultaneously vasopressin did not induce necrosis of the renal cortices. These findings suggest that androgen receptors of the kidney may take a part in eliciting this phenomenon.

Animals

Renal necrosis.

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Analgesics