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At least 19 recordsLinked to original sources
PubMed1985

Laryngeal perichondritis and abscess.

Primary infection of the laryngeal cartilages has become rare in the antibiotic era. However, trauma, irradiation, a foreign body, or cancer may initiate the infection, particularly in the immunocompromised patient. We encountered three cases of perichondritis and abscess associated with airway intubation, nasogastric intubation, and external beam radiotherapy. Laryngeal perichondritis and abscess remain serious potential causes of laryngeal deformity and dysfunction.

Abscess↗
PubMed1990

[The effect of local UHF hyperthermia and a fractionated radiation dosage on the incidence of perichondritis during the treatment of laryngeal cancer].

Perichondritis in patients treated by a continuous course were noted in 12.5 +/- 1.5%, in patients treated by a split method--in 4.6 +/- 1.2%, in chemoradiotherapy--in 5.75 +/- 1.3%, in thermoradiotherapy--in 3.0 +/- 2.9%, and after synchronization using 5-FU and large fractions--in 30.5 +/- 3.9%. Complications appeared mainly during the 1st year (85%), after 2-3 yrs.--in 8.4%, later on--in 6.6%. Local hyperthermia did not cause an increase in the number of complications.

Adult↗
PubMed1980

[Problems of laryngeal reconstruction following perichondritis of the larynx (author's transl)].

The surgical reconstruction of the larynx following laryngeal perichondritis is an uncommonly published subject. Three cases with special problems are presented. The main points of management to be remembered are that: 1. the complete removal of all necrotic tissue is essential for the success of surgical rehabilitation; 2. the restoration of respiration, deglutition and phonation can be achieved with use of regional skin and composite skin and cartilage flaps.

Adult↗
PubMed1992

[Laryngeal carcinoma with laryngeal abscess].

We had encountered 5 cases of laryngeal carcinoma associated with abscess. Four of them were advanced laryngeal cancer with abscess induced by mechanical injury, and one with post-radiation laryngeal perichondritis & abscess formation. Management included total laryngectomy in 3 patients, partial laryngectomy in 1 patient, and resection of post-radiation abscess in one. Laryngeal abscesses are seen rarely today. Endeavour should be made to decrease such complication. The authors had presented their experience in the management of laryngeal carcinoma associated with laryngeal abscess, together with a review of the history and some of the current ideas about this problem.

Abscess↗
PubMed1997

Laryngeal tuberculosis at the end of the 20th century.

Despite the dramatic reduction in the incidence of laryngeal tuberculosis after the 1950s, the topic has now gained new interest due to claims that the disease has changed its clinical pattern. In the past, the typical patient was 20-40 years old with ulcerated laryngeal lesions, perichondritis, and advanced cavitary lung disease. We studied nine cases of laryngeal tuberculosis confirmed by histological examination. The microlaryngoscopy revealed tumour-like lesions and/or chronic non-specific laryngitis. There were no significant ulcerations or signs of perichondritis. The patients' ages ranged from 48.5 years to 69.3 years (mean, 59.4 years). In three of our patients (33 per cent) we did not find any pulmonary involvement, thus suggesting primary laryngeal tuberculosis or haematogenous spread. In conclusion, the numerous physicians who deal with the various laryngeal symptoms and diseases should be aware of the existence of laryngeal tuberculosis and the changing patterns of the disease (at least in the developed countries).

Aged↗
PubMedDate not supplied

Perichondritis of the larynx following radiation.

In a retrospective study of 348 patients receiving radiotherapy as the primary treatment for carcinoma involving the laryngeal region, perichondritis developed in 52--an incidence of 15%. Of these 52 cases of clinically diagnosed perichondritis, 50% had residual or recurrent carcinoma. A controversy exists regarding the value of frequent and multiple biopsies in these patients; disease will be missed if this is not done, but perichondritis and cartilage necrosis may result from infection introduced by repeated laryngeal manipulation. On the basis of this study the authors recommend an aggressive approach with close follow-up and multiple frequent biopsies as the data indicate an incidence of 50% recurrent or residual tumor when perichondritis is present.

Humans↗
PubMed2003

Late laryngo-tracheal cartilage necrosis with external fistula 44 years after radiotherapy.

Major late complications, following radiotherapy of head and neck carcinomas, such as laryngeal oedema, perichondritis and chondronecrosis usually occur between three and 12 months after treatment. However, the present case displayed necrosis of the laryngo-tracheal cartilage and ulceration of anterior neck skin with a tracheal fistula 44 years after irradiation. The reasons for the long interval between irradiation and late complications may be explained by long-standing hypovascularity and/or infection of the irradiated area. Histological study revealed chondronecrosis without inflammatory cells in the laryngo-tracheal cartilage and bacterial colonization of subcutaneous tissue. Necrotic tissue was removed and tracheostomy was performed. The fistula was almost completely closed using a delto-pectoral cutaneous flap and the clinical course of patient has been good. This paper demonstrates the possibility of laryngo-tracheal necrosis in cases that had received radiation as long ago as 44 years.

Aged↗