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At least 19 recordsLinked to original sources

[Clinical evaluation on second stage reconstruction for laryngostenosis after partial laryngectomy for laryngeal cancer patients].

OBJECTIVE: To present a new method of decannulation for laryngostenosis patients after partial laryngectomy and extended partial laryngectomy, and restoration of the essential functions of larynx and normal neck appearance. METHODS: Nineteen cases of laryngostenosis after partial laryngectomy and extended partial laryngectomy were treated with second stage reconstruction. The patients had been treated by vertical laryngectomy (6/19) using extended vertical laryngectomy (11/19) and frontolateral laryngectomy (2/19). Among these patients, second stage reconstruction of larynx was performed by using rotary door myocutaneous flap (17/19). Stemohyoideus flap (1/19) and sternocleidomastoid flap (1/19). RESULTS: Three and five year-survival rates were 91.7% (11/12) and 3/5, respectively. Over-all decannulation rate was 84.2% (16/19), but 94.1% (16/17) in patients with rotary door myocutaneous flap and 0% (0/2) in both patients with sternohyoideus flap and sternocleidomastoid flap. There were 3 decannulation failures (15.8%). All patients resumed acceptable voice, 94.7% (18/19) enjoyed satisfactory phonation, but 5.3% (1/19) showed severe hoarseness. All except 2 patients returned normal swallow function. The latter 2 patients experienced mild abnormal swallow during eating fluid food in early stage of surgery, but had normal swallow function after 1-2 weeks. CONCLUSION: Functional laryngectomy is a radical operation in selected cases with advanced laryngeal cancer. The second stage reconstruction with bi-pedical rotary door myocutaneous flaps can help decannulation in patients who developed laryngostenosis after partial laryngectomy and extended partial laryngectomy, and restore the essential function of larynx and normal neck appearance.

Adult↗

[The causes and management of laryngostenosis in clinical stage I, II laryngeal cancer patients after decannulation].

OBJECTIVE: To investigate the causes and management of laryngostenosis in clinical stage I, II laryngeal cancer patients after decannulation. METHOD: The causes of seventeen cases laryngostenosis after decannulation were analyzed and various operations were carried out according to the causes. Two cases were treated by laser through fibrolarnygoscope, granulation tissue in laryngeal cavity were resected by selfretcuining laryngoscope in two patients. The laryngeal cavity scar was removed and the epiglotic flap, bi-pedicled myoperichondral flap, platysma myocutaneous flap were utilized to reconstruct the laryngeal functions in ten patients. Three patients were treated by total laryngectomy. RESULT: Except for three cases of total laryngectomy, thirteen cases were decannulated successfully after the second operation, decannulation rate was 92.86%. CONCLUSION: The scar hyperplasia and granulation tissue are the major causes of secondary laryngostenosis after decannulation in clinical stage I, II laryngeal cancer patients. Most of them regained own respiration, swallow and voice function.

Adult↗

[The use of the CO2 laser in the treatment of laryngostenosis and tracheostenosis].

The authors show the possibilities of using the laser CO2 in treatment of both laryngostenosis and tracheostenosis in 54 patients. In the article various forms of treatment of laryngostenosis and tracheostenosis as well as the results of the therapy have been presented. On the basis of the cases treated so far, the prospects of using the laser CO2 in this form of treatment have been found limited. The best results have been attained in treating the narrowings on a small surface. In case of complex laryngostenosis and tracheostenosis, the most effective treatment has been obtained by using the combination of the laser microsurgery performed on the larynx area along with the surgical resection of the narrowed segment of the trachea and the fusion "end to end". In some cases good results have been achieved by using the laser CO2 to remove postoperative scars of the larynx after partial laryngectomies.

Aged↗

Severe feeding problems and congenital laryngostenosis in a patient with 3q23 deletion.

UNLABELLED: Common clinical features of patients with 3q23 deletion include the phenotype of BPES (blepharophimosis, ptosis, epicanthus inversus and telecanthus syndrome), growth and mental retardation, microcephaly ear and nose dysmorphism and joint and digit abnormalities. We report on a 3-year-old girl with the phenotype of BPES, mental retardation, facial dysmorphism and camptodactyly. In addition, she had a congenitally small larynx and severe, chronic feeding difficulties. Chromosome studies revealed an interstitial deletion in the long arm of chromosome 3: del(3)(q23-q25). CONCLUSION: Congenital laryngostenosis and severe feeding problems may be part of the clinical syndrome caused by chromosome 3q23 deletion.

Abnormalities, Multiple↗

[Reconstructive surgery in laryngostenosis in children].

Methods of laryngoplasty with usage of costal cartilage autotransplant and segmental laryngeal resection were applied in 33 patients with laryngostenosis of various etiology. Decannulation of the patients during the first 4 months after beginning of the treatment was made in 75% patients with one-stage laryngoplasty. A new method of stenting in reconstructive operations on the larynx is proposed. The endolumen technique of silicon stent fixation isolated from tracheostome cannula is thought an optimal method of stenting. Surgery is optimal early after verification of the diagnosis. Early operations make it possible to optimize prognosis of one-stage treatment as they reduce the number of complications after long-term carrying of tracheostomic cannula as well as provide better socio-psychological adaptation of the patients.

Adolescent↗

[Long-term outcome of endoscopic CO2 laser surgery of cicatricial laryngostenosis in children].

Laryngeal scars were removed in 183 children 3 months to 15 years of age. A total of 538 endoscopic CO2-laser operations were made. Stents were inserted in 22 cases. Good and satisfactory follow up (1-8 years) results were obtained in 78 patients, unsatisfactory outcomes were recorded in 34 patients. Long-term results demonstrate that CO2-laser surgery of laryngostenosis is safe for children of different ages in that it does not hinder adequate development of the larynx.

Adolescent↗

[Indicators of immunologic reactivity in children with chronic laryngostenosis].

Immunological examinations of 40 children with papillomatosis and chronic cicatricial stenosis of the larynx included measurements of circulating immune complexes (CIC) and lysozyme in the saliva and serum as well as complement activity in serum. The examinations were performed regularly during treatment. It was found that immunobiological factors played an important part in the pathogenesis of papillomatosis and cicatricial stenosis of the larynx in children. It was shown that CIC and lysozyme concentrations in the saliva and serum as well as complement activity in serum increased. In the course of treatment all the groups displayed an increase of lysozyme in the saliva; patients with papillomatosis showed a decrease of the CIC concentration and those with cicatricial stenosis a decline of complement activity in serum. Involvement of the autoimmune component in the pathogenesis of the above diseases is discussed. Applicability of the results for controlling the therapeutic efficacy and predicting the outcome of diseases is considered.

Antigen-Antibody Complex↗

[Hyperbaric oxygenation in the postoperative treatment of children with cicatricial laryngostenosis].

Hyperbaric oxygenation (HBO) was used in the combined treatment of 20 children, aged 2 to 14 years, after reconstructive surgery of the larynx. All the patients had been exposed to tracheostomy. As a result, optimal regimens of compression and decompression of operated children were developed which were 0.025 ata/min and 0.04 ata/min, respectively. HBO was most effective when whole-body and regional hypoxia was applied simultaneously. The optimal pressure in an altitude chamber was 0.9 to 1.0 ata for as long as 40 to 50 min. HBO made it possible to shorten the degenerative-inflammatory process. Positive changes in pH of the wound were regarded as an indication of reductive aerobic metabolism there.

Adolescent↗