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Results for “Larva Migrans, Visceral”

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At least 19 recordsLinked to original sources
PubMed1979

Ophthalmic manifestations of visceral larva migrans.

Two patients had ocular manifestations of infestation with visceral larva migrans. In neither case did the eye involvement improve despite thiabendazole, local and systemic steroids, and cryotherapy. The lack of ocular response to treatment may be assumed to be because of organisms were already dead. Thiabendazole therapy is probably worth trying for early ophthalmic involvement with visceral larva migrans if the organism is still alive. In most cases the diagnosis of visceral larva migrans can be made with the help of the ELISA serum antigen determination so that enucleation of the eye will not be necessary for diagnostic purposes.

Child, Preschool↗
PubMed1978

Evaluation of serodiagnostic tests for visceral larva migrans.

Four serologic techniques for the diagnosis of visceral larva migrans caused by Toxocara canis, namely indirect hemagglutination (IHA), bentonite flocculation (BF), enzyme-linked immunosorbent assay (ELISA), and double diffusion in agar (Ouchterlony), were evaluated using sera sent to the Center for Disease Control from patients with a presumptive diagnosis of visceral larva migrans (VLM). Patients having 5-6 of the clinical or laboratory criteria for VLM were designated as cases while those with 0-2 criteria served as controls. The sensitivity of the ELISA was 78.3% compared to 18.2%, 25.8% and 65.2% for the IHA, BF, and Ouchterlony, respectively; the sepcificity of all four tests was greater than 92%. The predivtive value of positive test was greater than 85% for all tests except the IHA, while the predictive value of a negative test was greater than 85% only for the ELISA. The results of a ELISA were reproducible in different laboratories. Based on these findings, the ELISA using a larval antigen appears to be the serodiagnostic method of choice for VLM.

Adolescent↗
PubMedDate not supplied

[Visceral larva migrans].

The clinical records of patients with visceral larva migrans confirmed through laparoscopy and other tests are reviewed. This review was prompted by the admittance of two patients with this affection in the last years. Medical literature was reviewed, and conclusions are made.

Adolescent↗
PubMed1978

Visceral larva migrans and alveolar hydatid disease. Dangers real or imagined.

For both visceral larva migrans and alveolar hydatid diseases, it is the feces of companion animals that are the primary source of human infection. Clearly, whatever is done to reduce this form of environmental contamination and the prevalence of the parasites' infective stages will help to protect the health of the human population in the United States and Canada, particularly the children. Very important are appropriate anthelmintic treatment programs, especially for T. canis, and proper control of close associations between pets and people. Probably the known incidence of visceral larva migrans in humans and the range of its known pathogenicity will increase as better diagnostic methods become available. In addition, other animal helminths, for instance Toxocara cati and Toxascaris leonina, may become more substantially documented as causes of human visceral larva migrans. Until more is known of the geographical distribution and prevalence of Echinococcus multilocularis among animals in North America, it will be difficult to assess accurately the future significance of alveolar hydatid disease in the continent's human population. Another important advance would be the development of anthelmintics that are effective for somatic second stage larvae of T. canis, and others effective for adult or larval Echinococcus species. Meanwhile it is a most important responsibility of the veterinary profession to educate its clients thoroughly concerning these dangerous helminths.

Animals↗
PubMed1978

Visceral larva migrans. A review and reassessment indicating two forms of clinical expression: visceral and ocular.

Visceral larva migrans is a disease in which the larvae of animal parasites invade human tissues but do not complete their life cycles. The most frequent cause of this illness in children is the dog roundworm, Toxocara canis. A review of the literature, as well as our clinical experience, indicates that there are two forms of clinical expression: one, visceral, and the other, ocular. In general the clinical and laboratory abnormalities (hepatomegaly, recurrent pneumonia, eosinophilia, and hyperglobulinemia) usually associated with visceral disease are absent in children with ocular abnormalities. Conversely, there is a general lack of eye complications in patients with systemic disease. Reasons for these variations in clinical expression are unknown, but immune responses of the host and the antigenic composition of the parasite may be contributing factors.

Adrenal Cortex Hormones↗
PubMed1975

Anti-inflammatory activity of thiabendazole and its relation to parasitic disease.

In 6 differnet animal assays in the laboratory, thiabendazole had clear anti-inflammatory effect, though it was less potent than aspirin in all assays. These findings add support to clinical suggestions that the drug may have anti-inflammatory properties in man. Such properties may contribute to the clinical response observed following the use of thiabendazole in cases of trichinosis, cutaneous larva migrans, visceral larva migrans, dracunculosis and scabies. In parasitic infections in which corticosteroids are commonly used in clinical management, notably trichinosis, the fact that thiabendazole does not appear to have immunosuppressive activity may confer an added clinical advantage.

Animals↗
PubMed1976

The specificity of nematode allergens in the diagnosis of human visceral larva migrans.

Extracts of nematodes have been used as skin test antigens in the diagnosis of nematode infections for many years. Ascaris lumbricoides and Toxocara canis are two nematodes commonly involved in human parasitism, the latter being associated with the clinical condition of Visceral Larva Migrans. In vitro and in vivo experiments reported in this paper confirm experimentally, as well as clinically, the existence of cross-reacting antigens between T. canis and Ascaris spp., and probably between T. canis and other nematodes. These cross-reactions compromise the usefulness of skin tests in the diagnosis of such parasitic infections.

Allergens↗
PubMed1975

Dual infections of mice: visceral larva migrans and sublethal infection with Japanese encephalitis virus.

Experiments in 3 weeks old albino mice with Toxocara canis and sublethal infection with JE virus established a marked synergestic effect in dually infected mice. The results are discussed to indicate the possible role of visceral larva migrans in creating exploxive outbreaks of "acute encephalopathy syndrome" in individuals having simultaneous infection with a virus (es) which, alone, might produce only mild illness. The nature of the possible mechanisms involved yet remains to be understood.

Animals↗
PubMed1976

[Demonstration of antibodies during experimental toxocarosis using antigenic extract prepared from the adult parasit].

The detection of antibodies in subjects with visceral larva migrans syndrome caused by Toxocara canis is usually carried out with antigenic larvae, whose preparation presents some difficulties. Results obtained using extracts prepared from adult parasites show that such antigens are quite suitable for the detection of antibodies present in visceral larva migrans syndrome. This phenomenon is easily understood when one considers that there are numerous antigenic points in common between the different stages of the evolution of this parasite.

Animals↗
PubMedDate not supplied

[Capillaria hepatica. Report of the 2nd cased found in the Mexican Republic].

The 2nd. case of Capillaria hepatica seen in the Mexican Republic is reported together with clinical and laboratory findings of the visceral larva migrans syndrome, diagnosis which was made at the Hospital of Specialties of the Mexican Social Security Institute at Puebla, Pue. Mex. Same considerations are made regarding the biological cycle, its morphological characteristics and a review of the present state of the pathology, evolution and prognosis of the illness is made, focusing the attention to an immunological trend, as a close origin of the illness. Thus, it is concluded that an early recognition and diagnosis leads to an a adequate treatment that will be benifical to this kind of patients.

Capillaria↗