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At least 19 recordsLinked to original sources
PubMed1990

Prospective randomised trial of laser therapy only and laser therapy followed by endoscopic intubation for the palliation of malignant dysphagia.

Forty six consecutive patients admitted for the relief of malignant dysphagia were prospectively randomised to receive laser therapy only or initial laser therapy followed by endoscopic intubation. Twenty patients were treated in each group with six exclusions. The patients' swallowing ability was assessed before and during the remainder of their life on a 0-4 scale with 0 being normal swallowing and 4 total dysphagia. The patient's quality of life was measured at the same times, using a physician's assessment (QL index) and the patient's own assessment using a linear analogue self assessment (LASA). There was a significant correlation between all the QL index and the LASA scores collected (n = 126; rs = 0.594, p less than 0.001). The mean monthly dysphagia grade correlated with the QL index (rs = 0.433, p less than 0.001) and the LASA (rs = 0.272, p less than 0.002). There was no significant difference in the dysphagia grade before or after treatment in either group. Dysphagia fluctuated more in those treated with the laser only, however, than in those with a tube inserted. There was also no significant difference in the quality of life measured between the two groups of patients. The complication rate (laser only 10%, laser/intubation 40%, p less than 0.05) was significantly higher in intubated patients. The recurrent dysphagia rate (laser only 25%, laser/intubation 45%, NS) was higher in patients treated with intubation, but they required fewer endoscopic procedures. Overall both procedures were effective in relieving dysphagia and in maintaining quality of life. There was no procedure related mortality in either group.

Adenocarcinoma↗
PubMedDate not supplied

[The laser therapy and laser acupunture of patients with chronic recurrent aphthous stomatitis].

Laser therapy and laser acupuncture of the biologically active sites were administered to 24 patients with chronic recurrent aphthous stomatitis. The biologically active sites were selected individually with due consideration for the underlying somatic condition. Good results were achieved in the patients with the fibrous form of chronic aphthous stomatitis. Secretory and serum immunoglobulin levels were monitored over the course of laser treatment.

Acupuncture Points↗
PubMed1986

Endoscopic applications of laser therapy.

Lasers have provided a new surgical tool that has several distinct advantages: It is effective at a distance ("no-touch" technique). It can cut, coagulate, and vaporize depending on the wavelength, energy, and tissue characteristics. Laser energy can be carried through flexible fibers and so can be used in previously inaccessible sites. Endoscopic laser surgery can now be successfully used for control of bleeding, palliation of obstructing tumors, detection in microscopic stages, and possibly as definitive treatment of small malignant tumors. The indications for the use of lasers and their successful application will undoubtedly increase in the near future.

Aged↗
PubMed1988

Focal occlusion of the rabbit carotid artery by endovascular laser therapy.

Laser energy was fiberoptically transmitted into the carotid artery of a series of rabbits to induce an acute focal arterial occlusion. Temporary interruption of blood flow during the treatment was necessary to achieve an occlusion. The arterial occlusive effects of three wavebands of laser energy were compared and the violet band proved the most effective when using 0.3-0.5 Joules/second for 25-30 seconds. There was always the risk of vascular perforation during treatment when laser energy emission was from a bare-tipped optical fiber.

Animals↗
PubMed1989

[Palliative treatment of malignant stenoses of the esophagus and cardia: laser therapy versus laser + high-dose-rate Iridium 192 afterloading therapy. A prospective randomized study].

In order to compare the local efficiency of two different therapy modalities, 37 patients with advanced inoperable tumors of esophagus and cardia were evaluated hitherto in a prospective randomized study. Twenty patients received an exclusive laser treatment, 17 were additionally submitted to three high-dose-rate iridium-192 afterloading irradiations (single dose at the reference point 1 cm radially to the source: 7 Gy). In both groups, 15 patients died whose survival times were not different (125 versus 130 days), however, a beneficial influence was exerted by the afterloading therapy with respect to the duration of the palliative effect (67 versus 28 days) and the hospitalization time (25 versus 48 days).

Adenocarcinoma↗
PubMed1987

Prolonged survival and effective palliation in patients with squamous cell carcinoma of the esophagus following endoscopic laser therapy.

Endoscopic laser therapy provides effective symptomatic palliation for patients with squamous cell carcinoma of the esophagus. To investigate whether this treatment also prolongs survival, a retrospective case-control study was performed. Ten patients with squamous cell carcinoma of the esophagus, diagnosed between 1983 and 1985, were treated with the neodymium: yttrium aluminum garnet laser (Cooper Lasersonics, Model 8000, Santa Clara, CA). Twenty patients with the same diagnosis observed between 1979 and 1984 served as age-matched controls. There was no significant difference in sex, race, location of the cancer, prior treatment, or dysphagia scores for the two groups. Laser therapy produced a significant improvement in the mean dysphagia score. Life table analysis demonstrated a median survival of 17.5 months for the patients treated with endoscopic laser therapy compared with 5.7 months for the control subjects (P less than 0.05). One-year survival after laser treatment was 75%, compared with 20% in the control group (P less than 0.05). These results suggest that endoscopic laser therapy is effective for prolonging survival and improving the quality of life in patients with squamous cell carcinoma of the esophagus.

Actuarial Analysis↗
PubMed1992

[221 cases of laparoscopic laser therapy].

Laparoscopic laser therapy, using a Nd:YAG laser and an Olympus laparoscope, was performed in 221 cases. 0.5% dicaine spray was used intraperitoneally. The types of operations performed were tubal sterilization in 110 cases, vaporization of endometriotic lesions in 76 cases, lysis of pelvic adhesions in 13 cases, salpingostomy in 11 cases, salpingostomy for tubal pregnancy in 10 cases, and fenestration of cyst of Morgagni in one, the rate of success was 98.2% in tubal/sterilization. In 71 cases of endometriosis the pregnancy rate was 32.7% for R-AFS stage I-II, and 25.0% for stage III-IV cases. The advantages and techniques of the laparoscopic laser therapy were discussed.

Adult↗
PubMed1985

Practical considerations of endoscopic laser therapy.

Endoscopic laser therapy in an institution requires commitment to ongoing education and service. Cooperation of physicians and hospital administration, along with acceptance by the public, is essential. Planning for equipment, personnel, space, operational procedures, safety, and cost is vital. Requirements for a functional laser unit are discussed. The case distribution for the initial 7 months of operation in the Greenwich Hospital Laser Center is presented.

Adult↗
PubMed1987

Palliative laser therapy.

Endoscopic laser treatment has been tried for hemostasis, relief of stenosis and reduction of tumor volume in advanced upper gastrointestinal cancer. This form of treatment was found to be effective for each purpose, but success was usually only temporary. Thus, it was considered that endoscopic laser therapy for problems of advanced upper GI cancer could perhaps be improved by modifying the technique and/or developing new methods, such as the combination of the laser with other therapies.

Aged↗
PubMed1990

Indication and results of endobronchial laser therapy.

Endobronchial laser therapy will be carried out predominantly at obstructing bronchial carcinomas of the major airways. Concerning tumors distal of the bifurcation, corresponding pre-examinations (angiography, bronchography, fluoroscopy) should make it sufficiently probable that, after the recanalization of a bronchus, the patient will have a functional benefit. At non-completely obstructing tumors an occlusion of the bronchus may be prevented by an endobronchial laser resection. Only then is scarred stenosis suitable, if it concerns membranous changes; longer stenosis bring poor long-term results only. At a larger endobronchial bleeding the laser is not suitable for controlling the hemorrhage. The long-term results of the therapy for benign endobronchial lesions are good. The results of malignant changes depend basically on the localization and on the growth rate of the tumor. With a careful selection of patients very good immediate results may be obtained at nearly all endobronchial lesions.

Airway Obstruction↗
PubMed1989

Enhancing the carotenoid content of atherosclerotic plaque: implications for laser therapy.

Selective laser ablation of human atherosclerotic plaque is possible because endogenous carotenoid pigments found in atherosclerotic plaque confer a twofold preferential absorption of laser radiation at 450 to 500 nm. In this study, patients with carotid endarterectomy were pretreated with oral beta carotene to determine if the carotenoid content and therefore laser selectivity of plaque could be increased in vivo. Beta carotene-treated patients had a significant, nearly twofold increase in their plaque carotenoid concentration, which increased from 0.22 to 0.40 microgram beta carotene/mg cholesterol. These results suggest that selective ablation of atherosclerotic plaque may be enhanced by pretreating patients with doses of oral beta carotene for short periods of time.

Aged↗
PubMedDate not supplied

[Current possibilities and prospects of using gas lasers in medicine. Laser therapy].

Local laser radiation of human organism for therapeutical purposes can be looked upon as an efficient and controlled method of normalization of functioning of a number of organs. Laser units designed on the basis of industrial gas lasers are used on a large scale for treatment of vascular diseases and related ischemias in various parts of the human body.

Humans↗
PubMed1990

[Laser therapy in dust bronchitis].

Laser therapies of 43 dust bronchitis patients (4 cases in 1st stage and 39 cases in 2nd stage) were performed in comparison with routine therapeutic procedures of 28 patients (6 cases in 1st stage and 22 cases in 2nd stage). 14 acupuncture points were selected. A good therapeutic effect was attained in 16.3% sample group and 7.1% control group patients, satisfactory results--in respectively 58% and 42.9% cases, insignificant results--in 25.6% and 50% cases. Along with the favourable therapeutic effect, a positive influence of laser therapy on the immune system was established, particularly on the immunity T-system, in dust bronchitis cases. Laser therapy was recommended as part of complex treatment procedures for dust bronchitis patients.

Acupuncture Points↗
PubMed1990

[A comparative evaluation of the results of using a method for the endoscopic denervation of the corpus gastricum and for local laser therapy in the combined treatment of patients with duodenal ulcers].

The authors provide the results of the treatment of patients with duodenal ulcers using common conservative therapy, local laser therapy and endoscopic denervation of the body of the stomach. Inclusion of endoscopic treatment methods into multimodality treatment brought about the enhancement of the treatment efficacy, more pronounced with endoscopic denervation.

Adolescent↗