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Notes on the history of leprosy in Louisiana.

In the late 1880s it became apparent in Louisiana that leprosy was endemic in the southern part of the state. Initially, the intention was to establish a leprosy hospital in the city of New Orleans, close to medical facilities, and where the bulk of the patients were to be found. The establishment, instead, of an isolated leper colony at the run-down plantation at Carville, 85 miles up-river, was the result of community indifference, misunderstanding of the nature of the disease, and expected depreciation of property values. Fear of the disease was a secondary matter. The practice of locating residential facilities for the chronically ill at long distances from the centers of physician practice and medical research continues to this day. Interestingly, the arguments that permit this to happen have not changed appreciably from those of a century ago.

History, 19th Century

[Lesions of the auditory nerve in leprosy (author's transl)].

A study of 260 male patients in the Alexandria leper colony showed that 15% of them had uni- or bilateral perception deafness. The lesion was of the retro-cochlear type and has to be related to lesions of the peripheral nerves.

Adolescent

A sociological study of leprosy cases in the Gandhi Kusth Ashram, Jodhpur (Rajasthan).

A Sociological study was carried out in respondents of a Lepers Colony (Gandhi Kusth Ashram), Jodhpur. An attempt was made to study the knowledge about causation of Leprosy, age at onset, and treatment. The reason for leaving their original place of origin (South India) was enquired. A majority (95.2%) of patients were Hindus, had onset of leprosy in the age group of below 20 years to 30 years (80.94%) had a literacy rate of 6.3% only. A history of contact with a case of leprosy could be traced in 38% but within the family only in 11.9%. The infection as a cause of leprosy was recognised only by 3.57% patients but a majority had no idea about aetiology (70.24%) or thought it to be due to punishment for past sins (3.57%) or due to supernatural causation (1.19%). Most of them (70.2%) left home for fear of losing family prestige and to hide the disease (25.00%) or hatred of other family members (4.76%).

Adolescent

A bacteriological assessment of multibacillary cases in leprosy colonies after 4 1/2 years of multidrug therapy.

In this presentation we have devised a novel way of calculating the total bacterial quantum in 100 (78 LL and 22 BL) multibacillary leprosy patients living in leprosy colonies. The calculation is based on Ridley's logarithmic scale. We have also attempted to assess the reduction in the bacterial quantum as a result of intervention through multidrug therapy (MDT). 53% of the patients rendered bacteriologically negative within two years of treatment of MDT and 94% at 54th pulse dose i.e. at 54th month. The bacterial quantum in human source as leprosy patients was calculated thus--Average BI of the group X Number of patients in each group X Multiplication factor devised as per Ridley's Bacterial Index (BI). By applying this purely arithmetic formula, it was found that 99.8% of the bacterial load is harboured in leprosy patients having BI more than 3. The introduction of MDT initiated the reduction in total bacterial quantum "based on above arithmetic scale" was achieved very fast i.e., from 100% to 5% at 12 months and to 0.4% at 24 months. We believe that if one wants to achieve leprosy control through a reduction in total bacterial quantum within a specific period, leprosy cases with BI more than 3 should be treated on priority basis.

Colony Count, Microbial

Prevalence of leprosy in slums in Bombay including a leprosy colony.

Transmission of leprosy which is related directly to the total quantum of infection in the community as a whole is decided by the existence of patients suffering from progressive and infectious forms of leprosy and their movement from place to place. This information is of great importance in cities like Bombay to identify the priority areas as targets towards which control efforts should be directed. In this presentation an attempt has been made to compare the leprosy survey figures from three different situations in the city. Selection is arbitrary, not made on statistical basis. The data of particular importance is from a leprosy colony located in North Bombay representing a hyperendemic situation and a normal slum adjacent to this colony, movement of population between these two colonies being free. Age specific prevalence rates of leprosy after examining more than 80% of population from these colonies are compared with data derived from normal slums situated elsewhere in the city. The figures reveal varying prevalence rates marked by an increasing trend in the prevalence figures, leprosy colony representing the largest pool of infection. These figures indicate that wider statistically planned investigations on similar lines in urban areas may provide epidemiological data useful for planning control measures on a more rational basis.

Adolescent

A study of medico-social problems of the inmates of a leprosy colony in Mysore.

A study of the inmates of a leprosy colony in Mysore revealed that there were more male cases and that the deformities were also more common among the male patients. There was no cases among inmates below 20 years of age group 31-50 years. 93.2% of the inmates were illiterate and 96.6% of the patients were ignorant of the cause, spread, prognosis of the disease and prevention of disabilities. This indicated an urgent need of health education among the leprosy patients and their families. All the inmates, including the apparently healthy relatives reported loss of income due to disease and disabilities. Rehabilitation of the inmates by raising poultry, breeding sheep and sericulture activities must be encouraged.

Adult