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On the distribution of some genetic markers in libya.

On a sample of N equals 169 nonrelated blood donors from Libya several blood group, serum protein group and enzyme frequencies are within the range of those of other Caucasoid populations. However, the frequencies of cDe, Jk-a, Fy-c, Hp-1, Gc-1, aP-b and AK-1 show some greater differences and seem to indicate certain Negroid influence on the genetic composition of our Libyan sample. This assumption is conceivable considering the racial history of Libya.

Acid Phosphatase

A survey of ticks on farm animals in Libya.

Thirteen species of ixodid ticks and two species of argasid ticks were collected during a three-year survey of 58 farms in Libya. These included Boophilus annulatus, B. microplus, B. decoloratus, seven species of Hyalomma, Rhipicephalus sanguineus, Rh. evertsi, Rh. bursa, Argas persicus and Ornithodoros foleyi. This is the first recording of B. microplus, B. decoloratus and Rh. bursa in Libya. Of 20,391 animals examined by random sampling, 2020 (9.6%) had ticks; particularly common were Hy. dromedarii on camels, Hy. impeltatum on sheep and Hy. excavatum on cattle. The tick found most frequently overall was Hy. dromedarii.

Animals

Haemoglobinopathies in Libya.

Electrophoretic study of haemolysates from five hundred and forty-five subjects from the University of Garyounis, Benghazi, was carried out to find out the incidence of abnormal haemoglobins in Libya. Abnormal haemoglobins were encountered in 23 subjects of unrelated families, giving an overall incidence of 4.2 per cent. Sixteen of these subjects had Hb-AS trait (3.0%), Five subjects had Hb-AC trait (0.9%) and two subjects had Hb-AD trait (0.36%). Present study indicates that the incidence of abnormal haemoglobins in the indigenous population of Libya is low.

Anemia, Sickle Cell

The incidence of red-green colourblindness in the populations of Tripolitania, Cyrenaica and Fezzan in Libya, and of the Kikuyu, Kamba, Taita, Taveta and Luo tribes of Kenya.

The results of surveys of colourblindness carried out using the Ishihara test cards in Libya and Kenya, involving 384 and 504 individuals respectively, are reported. The Libyan samples, drawn from three geographically distinct regions of the country, are relatively homogeneous. The Kenyan samples, on the other hand, are heterogeneous, but in toto they display a markedly lower colourblindness percentage than do the Libyans. The Kenyan data are in broad accord with the other data available for sub-Saharan African populations. There are very few sets of comparative data available for North African populations, but the Libyan material displays a lower incidence of colourblindness than the values reported in European populations.

Color Vision Defects

Serological and clinical investigations of human hydatid case in Libya.

Fifty surgically confirmed cases of hydatid disease in Eastern Libya were investigated. Of these, 30 had cysts of the liver, five had extra-hepatic abdominal cysts and 15 had cysts in the chest, including the lungs. Ten cases of malignancy of the liver and five cases of malignancy of the lung were used as controls. Differential diagnosis of cancer was made by measuring the ESR and glycoprotein levels (elevated x 4 and x 3 respectively, in cancer cases). Serum bilirubin, SGOT, SGPT and serum alkaline phosphatase levels were also significantly raised in malignancy, while the total protein levels and eosinophilia were the same in both diseases. The intradermal test was positive in 88%, the haemagglutination test in 86% and the complement fixation test in 70% of cases. In the post-operative follow-up, complement-fixing antibodies disappeared somewhat faster than did the haemagglutinins. The positive skin test cases, however, remained positive throughout the 12-month follow-up period.

Blood Sedimentation

Pregnancy hepatitis in Libya.

The death-rate from hepatitis in pregnant women in Libya is high. Of 922 hepatitis patients treated during 1975, 377 were males and 545 were females. The case fatality-rate was 0.53% for males and 7-67% for females. In 293 pregnant women it was 12-97% compared with 1-6% in 252 non-pregnant women. In pregnant women deaths occurred mainly in the last trimester. Although 18-4% of the male patients and 15-2% of the women were hepatitis B surface antigen (HBsAg) positive, no patient shown to be antigen-positive died. The frequency of hepatitis in the second half of the year fell both in pregnant women and in the general population, suggesting a warning hepatitis-A epidemic. The exact cause of the high mortality in pregnant women is not clear, but it may have a nutritional basis.

Adolescent

A survey of mites on farm animals in Libya.

In 1985-1988, 2287 farm animals (cattle, camels, sheep, goats, horses, donkeys, dogs and rabbits) suspected of carrying parasitic mites were examined at 58 farms throughout Libya. Mites were identified on 1303 of these animals. The commonest parasites on cattle were Psoroptes and Chorioptes, on camels and sheep were Sarcoptes and Psoroptes, and on goats were Sarcoptes and Demodex. Infested horses carrier Psoroptes or Chorioptes, and one donkey carried Sarcoptes. Otodectes was common on dogs, but Sarcoptes was rare and no Demodex were seen. Rabbits often had psoroptic ear mange or sarcoptic body mange. Dermanyssus gallinae and Ornithonyssus bursa were seen on chickens, but no mites were found on pigeons, ducks or turkeys.

Animals

Impact of anti-tuberculosis legislation in Libya on the prevalence of primary and acquired resistance to the three main drugs at a majortuberculosis centre.

The effect of legislative actions taken in 1973 on the prevalence of primary and acquired drug resistance was studied from the records on the Regional Tuberculosis and Chest Diseases Centre in Benghazi during the period June 1971 to August 1976. There were available for analysis 771 culture-positive cases of newly diagnosed pulmonary tuberculosis in Libyan nationals, and 789 cases of both Libyan nationals and others with positive cultures during treatment. The legislative actions included screening of all foreign and local workers for tuberculosis before employment or in the course of employement for those already employed and strict control of the use of antituberculosis drugs, which were not made available to private practitioners, private pharmacies, general dispensaries and general hospitals. The proportion of newly diagnosed cases with resistance to one or more of the 3 drugs streptomycin, isoniazid, PAS (resistance to PAS was negligible, occurring in only 0.7% of the whole series) during the first 3 months of the survey was 16.6%. During the first 9 3-month periods there was a small decrease of 0.15% per quarter. However, after adoption of the antituberculosis measures in mid-1973 the rate of decline accelerated to 0.61% per quarter, a 4-fold increase over the earlier rates (P less than 0.001 for comparison of rates). If the rate of decline observed in the first 9 quarters had continued unchanged the expected proportion resistant at the end of the period would have been 13.5%, compared with the observed proportion of 8.6%. The proportion of patients under treatment from whom resistant cultures were isolated was 33.3% in the first quarter. It remained at about this level until the 14th quarter, approximately a year after the legislation came into force, when the proportion began to decline. By the end of the period it was only 14.7%.

Adolescent

Investigations into rhizosphere microflora of some plants in Libya.

The present investigation deals with the effect of raising Hordeum vulgare and Arachis hypogaea at two different stages on the microbial rhizosphere population. The studies were extended to reveal the microbiological occurrence in different horizons of a soil profile corresponding in length to root regions. Bacteria were most abundant, followed by actinomycetes while fungi were less abundant and more restricted in their distribution. The three groups of microorganisms varied markedly in the rhizosphere of the two plants under investigation. The plant age had a great influence on the frequency of occurrence of the different microorganisms. One strain of bacteria, six fungi and the members of the grey series of Streptomyces were dominant. Actinomycetes and fungi diminished with the depth of soil, while the bacterial counts increased.

Actinomycetaceae

HLA polymorphism in Israel. 6. North African Jews from Libya.

Phenotype and gene frequencies of antigens at the A and B HLA loci were determined in a sample of 89 random Libyan Jews now settled in Israel. Most antigens at the A locus are within the range found in European populations while, at the B locus, the frequencies differ from Caucasoid populations: B7 is usually rare (1%), Bw35 is frequent (14%) and Bw40 very common with more than 10%. Thirteen percent of Libyan women whose sera were screened for the presence of HLA antibodies gave positive results. Some of them are elderly women, about 15 years or more beyond their last birth.

Gene Frequency