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At least 19 recordsLinked to original sources
PubMed1977

Life graphs and life events.

The present study investigates changes in personal satisfaction over the whole life course by means of life graphs and their determinants. The life graphs were administered within a 4-year interval to 371 individuals (age 45-70). A modified version of the Holmes and Rahe life events scale, administered in the second interview, was used to ascertain the occurrence of four kinds of events: (1) children leaving home, (2) ill health, (3) death of family or friends, and (4) changes in work. Differences in height between the peak of the graph and the height at the current age is the measurement technique used with the life graphs. Events are found to play a different role at different stages of life and seem to be measured against an implicit schedule according to which the events are seen as traumatic or acceptable. Thus, the same event has different effects on perception of emotional state according to age.

Age Factors↗
PubMed1979

Life changes and perceptions of life and death among older men and women.

Although social scientists have suggested that feelings about life and death may be related, for the most part, theories of social gerontology have developed independently of conceptions of death and finitude. This study examines whether life changes are associated with concurrent life and death attitude types among older men and women. Data were analyzed from structured interviews conducted with 214 men and 354 women during the second phase of a longitudinal study of the aged in small towns. Individuals were identified as positivists, negativists, activists, and passivists. Controlling for sex and income, changes in four life areas were examined in relation to these perceptions of life and death. Some of the patterns varied by sex, suggesting that the same changes have different implications for the well-being of men and women in late life. In general, those who had experienced discontinuity were more frequently negativists or passivists, while continuity tended to characterize positivists and activists.

Aged↗
PubMed2026

Effect of Narrative-Based Palliative Care on Psychological Stress, Quality of Life, and End-of-Life Acceptance in Elderly Terminal Cancer Patients and Their Families.

ObjectiveThis study aimed to preliminarily evaluate the impacts of narrative-based palliative care on psychological stress, end-of-life acceptance, and quality of life in elderly terminally ill cancer patients and their family caregivers.MethodsThis single-center, small-sample randomized controlled study enrolled 50 elderly terminal cancer patients. Patients were randomly assigned to either the observation group or the control group (n = 25 each). The observation group received narrative-based palliative care, while the control group received routine standard care. Family psychological stress was assessed using the Relative Stress Scale (RSS), and patients' perceived stress was evaluated with the Perceived Stress Scale-10 (PSS-10). Caregiver satisfaction was measured using a hospital-developed questionnaire. Patients' quality of life was evaluated using the SF-36, Chinese Version of the Death Attitude Profile (DAP-C), and Pittsburgh Sleep Quality Index (PSQI), respectively.ResultsBaseline characteristics did not differ significantly between the two groups (P > .05). Post-intervention, the observation group demonstrated significantly lower psychological stress among family members and higher caregiver satisfaction (P < .05). Patients in the observation group reported better quality of life, improved sleep, and greater acceptance of death than those in the control group (P < .05).ConclusionAs a small-sample, single-center study, these findings offer preliminary evidence that narrative-based palliative care may reduce psychological stress in elderly terminal cancer patients and caregivers while enhancing patients' quality of life, sleep quality, and acceptance of death. However, the limited sample size, single-site design, and narrow inclusion criteria restrict generalizability. Larger multicenter trials are needed to confirm these results.

Humans↗
PubMed1977

Life events and schizophrenia. II. Impact of life events and symptom configuration.

This study investigates the impact of life events on symptom configuration in a group of 132 posthospitalized schizophrenics living in the community. Multivariate techniques were used to isolate specific dimensions of symptoms and to study the influence of life events, viewed in terms of number, the psychological control dimension, and qualitative nature, in contrast to other factors thought to determine symptoms. Life events exert their greatest influence on nonpsychotic symptoms such as anxiety, depression, and somatic concerns. Aspects of psychotic behavior such as gradiosity, delusions, and looseness of associations appear to be somewhat vulnerable to the impact of life events, particularly those events that are undesirable, social losses, and beyond individual psychological control. We discuss the findings in relation to the issue of causal effect in the study of life events and psychiatric impairment.

Anxiety↗
PubMed1978

Characteristics of the 'life spanning' phenomenon in Amoeba proteus. Independent nuclear and cytoplasmic ability to impose finite 'life span'.

Amoeba proteus given adequate food grows exponentially and clones of amoebae are normally immortal. After periods of food supply restriction to that necessary for maintenance, or food intake restriction by agitation, cells subsequently given a normal growth diet produce clones of finite life span. Reciprocal nuclear transfer between maintained and normal cells demonstrated that the nucleus and cytoplasm of maintained cells have acquired the independent ability to impose a finite life span on clones developing from cells whose other components are normal. In clones developing from maintained cells, inviable cell production is enhanced and inter-division times are prolonged. Inter-division times and clones mean doubling times do not show normal distribution.

Amoeba↗
PubMed1978

[Healthy nutrition - prerequisite for life enjoyment and quality of life].

Bad nutritional habits can cause or enhance various, especially chronic, diseases. The right amount of calories, an adequate composition and the distribution of the meals over the day are the basis of good nutrition. A coordinating office could improve the information of our population, since many different professions must cooperate. Nutritions education must be improved. Industry, professional organisations, nutritionists, consumer organisations and specialists for communication must cooperate to solve the difficult problem of nutritional habits and to demonstrate that good nutrition can--as the gastrotonomy of the future--help to enjoy life.

Adolescent↗
PubMed1979

Social interaction and life satisfaction: an empirical assessment of late-life patterns.

Problems of social and psychological adjustment in later life have been examined by numerous investigators. Some have found positive relationships between social interaction and personal adjustment, while others have found interaction and adjustment to be unrelated. The purpose of the research reported here was to examine how different ways of measuring interaction may affect its relationship with personal adjustment. Data were obtained in interviews with 218 noninstitutionalized persons aged 70 and older. Findings indicate that both the number of persons interacted with, and the frequency of this interaction, are of little importance for the adjustment of older people. We suggest that the quality, rather than quantity, of social interaction is crucial to understanding adaptations to old age.

Aged↗
PubMed2026

Shielding the First 24 Postnatal Months of Life: A Proposal for a Prospective Cohort Study of Early-Life Electromagnetic Exposure and Autism Risk.

BACKGROUND: Autism Spectrum Disorder (ASD) involves Mirror Neuron System (MNS) dysfunction, driving core social and imitative impairments. Systemic physiological alterations such as autonomic dysregulation, mitochondrial dysfunction and neuroinflammation are known to impair synchronization and plasticity of neuronal clusters. A less-evident environmental cofactor, coinciding with rising ASD prevalence, is the considerable world-wide increase in electromagnetic radiation (EMR) overall exposure among children. Experimental evidence shows how low-intensity EMR influences cellular processes, via voltage-gated calcium channels (VGCCs), oxidative stress, and mitochondrial metabolism. The Resonant Convergence framework, allow to predict how chronic EMR exposure during the first 24 postnatal months of life can act as a factor in ASD pathogenesis. The best candidate mechanism is chronic Ion Cyclotron Resonance (ICR) detuning the Ca2+-calmodulin pathway, thus disrupting MNS synchronization. METHODS AND ANALYSIS: A prospective observational pilot cohort study (24-month follow-up) proposes to enroll 1000 full-term newborns into two arms: an EMR-reduced cohort (n = 500, rest and sleep-phase Faraday shielding) and a standard exposure cohort (n = 500). Exposure is quantified via radiofrequency (RF)/extremely low frequency(ELF) measurements, proximity analysis, device inventories and wearable dosimetry. The primary endpoint is a continuous neurodevelopmental trajectory score (joint attention, language, electroencephalogram (EEG) mu-rhythm); binary ASD diagnosis (Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), Autism Diagnostic Interview-Revised (ADI-R)) is a secondary, exploratory endpoint. Moreover, an optional genomic screening will evaluate gene-environment interactions within extremely low-frequency electromagnetic field (ELF-EMF) vulnerable pathways, including ASD-associated genes upregulated by RF via bromodomain and extraterminal protein (BET)-mediated epigenetic mechanisms. Analyses will employ risk ratios, Fisher's exact tests and logistic regression adjusted for confounders; mixed-effects and Bayesian modeling will evaluate longitudinal outcomes and exposure reduction effects. Given a 2-3% baseline prevalence, approximately 20-30 ASD cases are expected. The study is therefore powered for exploratory signal detection rather than definitive causal inference, providing the critical baseline data required to justify and design future confirmatory trials. Sex-stratified modeling will address the 4:1 male-to-female prevalence ratio. ETHICS AND DISSEMINATION: Ethics committee approval is not yet sought; full protocol review and approval will be obtained prior to the study initiation, in strict accordance with the Declaration of Helsinki. Written parental informed consent will be mandatory for all participants prior to enrollment. Study findings and methodological milestones will be disseminated through peer-reviewed international scientific publications. This protocol provides a structured methodological framework for the first prospective investigation of sleep-phase EMR reduction as a potential modulator of ASD incidence during early neurodevelopment. Results will inform adequately powered confirmatory trials in electromagnetic neurodevelopmental epidemiology.

autism spectrum disorder↗
PubMed1979

Schedule shifts, life quality and quantity--modeled by murine blood pressure elevation and arthropod life span.

During the span from 50 to 100 days and beyond, the male stroke-prone Okamoto rat develops systolic blood pressure measures in excess of 200 mm Hg. In the course of developing such a marked elevation in systolic blood pressure mean, this intermittently handled male Okamoto rat exhibits a statistically significant circadian rhythm with large amplitude. This amplitude may represent, at least in part, a response to intermittent handling; it is several times larger than the amplitude for spontaneously mesor-hypertensive (but not stroke-prone) female animals of the same age.

Aging↗