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[Comparative anatomical studies on the Jacobson organs of Nycticebus coucang Boddaert, 1785 (Prosimiae, Lorisidae) and Galago crassicaudatus E. Geoffroy, 1812 (Prosimiae, Lorisidae). I. Nycticebus coucang].

The goal of this research was to study the macroscopic and microscopic anatomy of the vomeronasal organ in Nycticebus coucang. Based on numerous measurements in cross-sections of all parts of the organ, three-dimensional graphs of the vomeronasal cartilage, the organ and the system of blood-vessels, situated around the organ, were drawn. Nycticebus has a well developed vomeronasal organ exhibiting a well developed sensory epithelium. The oral end of the organ opens into the middle part of the nasopalatine duct, which has an open connection with the cavum nasi and the cavum oris. The cartilago paraseptalis is connected with the cartilago ductus nasopalatini by the sickle-shaped part of the cartilago paraseptalis. An "outer bar", which is present in the vomeronasal cartilage of Tupaia, is absent in Nycticebus. The oral part of the organ contains nonciliated, pseudostratified epithelium with secretory crypts and goblet cells. In the main part of the organ the dorso-lateral wall consists of nonsensory, nonciliated, pseudostratified epithelium, while the sensory epithelium is situated in the dorsolateral wall. Serous glands, which are situated dorsal to the organ, open into the organ at its dorsal margin. Caudal to this part there is a long part of the organ without sensory epithelium. At its caudal end the organ is branched. The sensory epithelium of the vomeronasal organ is thicker than the sensory epithelium of the nose. It contains a nucleus-free space between the nuclei of supporting cells and the nuclei of sensory cells. The sensory epithelium contains about 92 000 receptor cells/mm2. Capillaries could not be seen in the epithelia of the organ. The vessels, which accompany the organ, are veins and capillaries. The dorsal veins exhibit thicker walls and a wider lumen than the ventral ones and are therefore better suited for the pumping-mechanism, as suggested by BROMAN (1920). Connective tissue, surrounding the organ, aids the pumping-mechanism of the veins.

Animals

[Cytogenetics of two Lorisidae (Nycticebus coucang and Perodicticus potto). Comparison with the lemurs and the simians (author's transl)].

The karyotypes of two Lorisidae (Prosimians) Nycticebus coucang and Perodicticus potto have been studied, using many banding techniques. These karyotypes are compared with each other and also with those of Microcebus murinus (Lemur) and of Cebus capucinus (Simian, platyrrhine). The karyotype of M. murinus appears ancestral to the other. That of the Lorisidae cannot be an intermediatry stage between the karyotypes of the lemurs and of the simians. An important part (12 p. cent) of the genome of N. coucang is comprised of heterochromatin ; it and the juxta centromeric heterochromatin stain negatively with C-banding techniques. C-banding therefore is insufficient to delineate constitutive heterochromatin, late replication being the only universal criterion.

Animals

Scaling of growth and life history traits relative to body size, brain size, and metabolic rate in lorises and galagos (Lorisidae, primates).

A broad range of variation in body size, brain size, and metabolic rate occurs within the primate family Lorisidae, thus providing an opportunity to examine the relationship of these three parameters to variation in growth and life history traits. Data on adult body weight, gestation length, lactation length, age at first estrus, litter size, and growth parameters were collected from a captive colony of four lorisid species, Loris tardigradus, Nycticebus coucang, Galago crassicaudatus, and G. senegalensis. The data presented here constitute the most complete life history information available for these poorly understood prosimian species. Correlation and allometric analyses were performed to determine the relationships between variables. Among the lorisids studied, adult body weight, adult cranial capacity, and relative cranial capacity did not predict variation in life history traits. Adult basal metabolic rate predicted most of the variability in gestation length, lactation length, and growth parameters. Lorisines differ from similarly sized galagines in having lower basal metabolic rates, slower growth rates, slower developmental rates, and smaller litter sizes, resulting in reduced reproductive potential. This may be a consequence of lorisine adaptation to a diet of toxic insects. Metabolic rate and diet may be among the most important parameters to examine in any study of life history evolution.

Animals

A quantitative approach to cytoarchitectonics. IV. The areal pattern of the cortex of Galago demidovii (e. Geoffroy, 1796), (lorisidae, primates).

The boundaries of neo- and allocortical areas of Galago demidovii are analyzed with an automatic quantitative procedure using an image analyzer. The results are summarized in a cortical map and compared with a cortical map of Tupaia. Galago shows a highly differentiated temporal lobe and no homogeneous peristriate area comparable to the classical concept of Brodmann's Area 19. Primary motor, somatosensory, auditory, and visual areas are delineated and shown to be surrounded by distinct secondary areas.

Animals

Concentrating capacity of the kidney and nitrogen partition in the urine in Perodicticus potto (Prosimii, Lorisidae, Lorisinae).

The concentrating ability of the kidney in Perodicticus potto was investigated. As the relation between this capacity and the thickness of the medulla has been stressed by Schmidt-Nielsen & O'Dell, the size of the various layers in the kidney was measured. Based on our observation that the potto may excrete uric acid in fairly high concentrations, the partition of nitrogen in the urine was also explored.

Animals

Chromosomal evolution in "lemurs". VI. Chromosomal banding studies of Galago senegalensis, Galago alleni, Galago demidovii and Euoticus elegantulus.

The karyotype of four Galagidae (Galago senegalensis, G. demidovii, G. alleni and Euoticus elegantulus) are studied and compared with the aid of various banding techniques. Many common chromosome segments were found, and it was possible to reconstruct a hypothetical ancestral karyotype for the family. It was also possible to show the relation between the chromosomes of Galagidae with those of two Lorisidae. The general scheme of chromosomal evolution of the Lorisiforms can be proposed, resulting from a common populational evolution followed by an accumulation of translocations, mostly of the Robertsonian type. Several pericentric inversions have also occurred in the trunk of the Lorisidae, emerging from this common population. Then, Galagidae have evolved, each species independently, by an accumulation of translocations, mostly Robertsonian, whereas Lorisidae have accumulated pericentric inversions prior diverging.

Animals

Thermoregulation in the slender loris (Loris tardigradus).

Thermoregulatory characteristics of slender lorises largely resemble those of other slow-moving Lorisidae: Body temperature is slightly below the normal mammalian level and basal metabolic heat production is only about half of the mass-specific standard. During cold exposure only a rather small body core is kept at a high temperature level whereas large parts of the body are allowed to cool. Contrary to the findings in other Lorisidae slender lorises are more tolerant against high environmental temperatures, largely due to the ability of considerably increasing evaporative cooling.

Animals

Morphological changes in the cochlear nuclear complex in primate phylogeny and development.

The primate cochlear nuclear complex exhibits several characteristic morphological differences in the various primate families from Lorisidae through Hominidae. The most striking differences occur in the organization of the dorsal cochlear nucleus in which the laminar pattern becomes progressively obscured. Granule cells form an external granular layer as well as being intermixed within the molecular and pyramidal layers in slow lorises and squirrel and rhesus monkeys. Whereas a prominent external granular layer remains in chimpanzees, granule cells are scant in other portions of the nucleus. Human adults lack an external granular layer. A small number of granule cells occur but with inconstant distribution. Primates lack the linear array of pyramidal cells oriented perpendicularly to the epithelial surface as seen in cats. The granule cell layer exhibits similar regression in development of the human cochlear complex. The external granular layer is prominent in the fetus but rapidly decreases in size after birth. It achieves its adult form prior to 18 months. The data suggest that neuronal attrition, or programmed cell death, may be the major mechanism accounting for the alterations that occur in the human granule cell layer. Other differences in cytoarchitecture, within the great apes and humans, include decreases in the small and giant cell populations of the cochlear complex. These changes, in consort with the organizational changes and reduction of granule cells as noted above, suggest a trend towards reduced intranuclear integration at the level of the cochlear nucleus coupled with encephalization of the auditory system.

Adult

Three-dimensional analysis of the arterial pattern of the upper limbs in Lorisiformes (Prosimiae, Primates).

A study of the arterial patterns of the upper limbs in Lorisiformes (Prosimiae), especially those of the rete mirabile and their correlating arteries, was carried out by three-dimensional arteriographic analysis. The rete displayed at least two types of plexiform distribution: (1) a vascular bundle in Lorisidae, which consists of a division of the main artery into a principal trunk surrounded upwards by about 50 small arteries, and (2) a simple network pattern in Galagidae, which, at most, is composed of simple vascular networks of the nature of a few widely scattered anastomoses. The arterial patterns of the upper limb in Lorisiformes are basically the same, but the position of divergence and the number and size of the vessels in the rete differ. The arterial patterns of the upper limbs in Lorisiformes closely resemble the development of the vessels in the 21- to 23-mm stages of human embryonic growth. In this study, we observed some similarity in the patterns between the rete mirabile and the superficial brachial artery in man.

Angiography