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Results for “MOUTH MUCOSA”

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At least 19 recordsLinked to original sources
PubMed2002

[Eosinophilic ulcer of the mouth mucosa. Differential mouth ulcer diagnosis].

Eosinophilic ulcers of the oral mucosa represent a rare, self-limiting disease of unknown origin. Single lesions occur typically in the oral cavity or on the lower lip. Characteristically, they have a short history and resolve spontaneously. Diagnosis is verified by the histologic feature of a deep polymorphic inflammatory infiltrate with numerous eosinophils. The clinical aspect shows a usually nontender ulcer with a white or yellowish base and elevated indurated borders or a tumor with central ulceration. Lymphadenopathy is not found. Differential diagnoses include malignant tumors and the primary stage of syphilis. We present three cases recently diagnosed in our department to show the characteristics and the different appearances of the disease. A 74-year-old woman presented with an ulcer at the base of the tongue, a 59-year-old man had one on the lower lip, and in a 48-year-old man the lesion was atypically located at the edge of the mouth. Here we demonstrate the importance of knowledge of the disease, its course, and the characteristic histology to avoid troublesome diagnostic and therapeutic procedures.

Aged↗
PubMedDate not supplied

[Local hyperthermia by means of ballon-type electrodes in combined therapy of patients with locally spread cancer of the mouth mucosa and lower lip].

Modification of the standard chemo- and radiotherapy with local hyperthermia gives evident positive results in treatment of patients with local cancer of tunica mucosa of mouth and lower lip. Since this area having uneven complex surface needs to develop radiofrequency emitting special applicators. We have used catheters with ballons filled with hypertonic solution as electrodes to adapt the mouth cavity. An electric field creating between these ballons and high surface adjustability makes this system come in useful.

Adult↗
PubMed1989

[Primary reconstructive operations in cancer of the mouth mucosa and oropharynx].

An analysis of primary reconstructive surgical treatment of 254 patients with carcinoma of the mouth mucosa and oral pharynx was made. The character of operative procedures for different localizations of the tumour is described. The primary reconstructive surgical treatment was shown to reduce the amount of postoperative complications to 11.4%, to keep intact the natural ways of respiration and nutrition at the early postoperative period. If without recidivation, about 70% of the patients continued working.

Adult↗
PubMed1986

[Efficacy of radiotherapy of cancer of the mouth mucosa].

An analysis of 10-year experience of a radiological department (962 patients) indicated late admission of oral mucosa cancer patients for specialized treatment: 75-85% of the patients were admitted with Stage II-IV disease. The assessment of the efficacy of radiotherapy according to the 3 and 5-year survival rates showed that better results were obtained for buccal mucosa cancer and the worst for mouth fundus cancer. Three-year survival rates could be considered sufficient for the assessment of buccal cancer therapy whereas a 5-year period was necessary for the rest of the cancer sites. Therapeutic results and stage were well correlated; in all the sites the results were worse in patients with Stage III-IV disease. Regional metastases are a poor prognostic sign, particularly fixed metastases in patients with tongue and mouth fundus cancer. Combined therapy turned out to be the most effective in tongue cancer. In different variants of dose delivery in time the most favorable results were obtained with small fractionation (a conventional course). However it should be noted that a split course was usually applied to weak elderly patients with advanced stages of disease.

Carcinoma, Squamous Cell↗
PubMed2003

[Experimental study of contraction loss effects of mouth mucosa by ethanol injection].

We began treating patients with simple snoring and obstructive sleep apnea syndrome (OSAS) with the coblator radiofrequency generator in our outpatient clinic from April 2001. Good clinical results have been obtained, but we noticed a contractile effect on mucosa from ethanol, which possesses marked sclerotic degenerative action on tissue as well as radiofrequency energy. We conducted a series of experiments in a guinea pig model to investigate the efficacy of local ethanol injection in contracting mouth mucosa. To examine the influence on respiration of liquid injection, physiological saline was gradually injected in decrements into the arch of the palate mucosa. We found that the safe dosage that did not bring about edema and subsequent dyspnea was under 10 microliters. Based on this finding, ethanol in concentrations of 50%, 70%, and 100% at volumes of 1, 2, 4, 8, and 10 microliters was injected into the arch of the palate mucosa in guinea pigs and changes in local field mucosa were observed daily. In the 50% ethanol injection, no clear contractile effect on mucosa could be observed at any dosage. In contrast, the 100% ethanol injection led to strong tissue impairment that caused extensive necrotic collapse of the local field mucosa, even when the dosage was down to the minimum of 1 microliter. We found that, injection of 70% ethanol at 1 or 2 microliters, however, resulted in formation of a local field mucosa wound of lesser degree that healed completely within a few days, associated with moderate contraction of mucosal tissue. We concluded that in moderate dosage, 70% ethanol seems to have the potential for the treatment of endermosis, such as uvuloptosia (elongated uvula) and hypertrophy of palate mucosa, as a useful mucosa contractile agent.

Animals↗