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At least 19 recordsLinked to original sources

Penetration of antibiotics into the normal and diseased maxillary sinus mucosa.

A micro-method was developed for determination of the concentrations of antibiotics in the mucous membranes of the maxillary sinus in man. At different times after the administration of antibiotics (potassium phenoxymethylpenicillin, lymecycline and bacampicillin) the concentration was determined in serum and in pieces of maxillary sinus mucosa obtained at operation. It was found that the concentrations in the mucosa varied within wide ranges during the first 60 minutes after the operation but in samples taken at 90 minutes the fluctuations between the individuals were within the standard error of the method. Concentrations well above the MIC values for the majority of bacterias found in sinusitis were registered in the peaks. Six hours after the administration considerable amounts of active antibiotics were still detected in the maxillary sinus mucosa.

Acute Disease

The mucociliary activity of the upper respiratory tract. III. A functional and morphological study on human and animal material with special reference to maxillary sinus diseases.

Local mucociliary activity (mucociliary wave frequency) was recorded in vivo and in vitro in maxillary sinus diseases. Activity was fairly normal even in cases with chronic purulent sinusitis. Scanning electron microscopy (SEM) sometimes showed a quantitative reduction of cilia. The mucociliary wave frequency was mostly about 1000 waves/min, and there was no in vivo/in vitro discrepancy. Antral mucosa was compared to adenoids, nasal polyps and healthy rabbit trachea. The mucociliary wave frequency was about the same in all materials.

Adenoids

Liability of ultrasound in maxillary sinus disease.

For the first time liability of of ultrasonography in diagnosing paranasal sinus disease was controlled in 256 patients with acute maxillary sinusitis as compared to irrigation findings and in 150 patients with persistent maxillary sinus disease using x-rays, sinoscopy and sinumanometry as controls. Confidence in diagnosing the presence of discharge ranges up 90%. In cases of total opacity of the sinus, ultrasonography helps differentiating mucosal swelling, tumor and discharge.

Acute Disease

Comparison of panoramic radiography and Water's projection in the diagnosis of maxillary sinus disease.

Pantomograms and Water's views were independently reviewed by two radiologists with regard to detection of maxillary sinus abnormalities. Panoramic radiography was found to be a better radiologic approach than the Water's projection for the detection of cystlike densities in the maxillary sinus. Cloudiness of the maxillary sinus and sclerotic change of adjacent bony structures were better demonstrated on the Water's view. These two techniques supplement each other and both should be used in order to obtain a more accurate diagnosis of maxillary sinus disease.

Humans

Maxillary sinusitis mimicking malignant disease.

The diagnostic features of both maxillary sinusitis and neoplastic disease of the antrum are described. In most cases the clinical and radiographic evidence will lead to the correct diagnosis. However, in the two cases presented here, the clinical and radiographic evidence of neoplastic disease of the maxillary sinus was not confirmed by biopsy and histologic examination. The significant fact that radiographic evidence of bone destruction of the antral walls can occur in maxillary sinusitis is discussed. This sign, together with a unilateral epistaxis, must always be considered as evidence of neoplastic disease of the maxillary sinus. Where there is any doubt, biopsy must be performed.

Aged

[Diagnosis, classification and therapy of cysts in the maxillary sinus region].

Cysts in the vicinity of maxillary sinuses pose special problems. In diagnosing them, it must be considered that pathophysiological processes must be considered common to both. The therapy demands knowledge of the physiology of the same anatomical sector plus considerations pertaining to the later necessary seat of the maxillary prosthesis. Methods of diagnosis and therapy are shown.

Cysts

[Dystrophy and necrosis following radiotherapy for maxillary cancer (author's transl)].

About 10% of patients developed severe sequelae following radiotherapy, which had been associated with surgical treatment, even though they were, or appeared to be cured. Complications affected the skin and soft tissues (causing skin retraction, loss of substance, and sometimes trismus) and bone (necrosis required surgical treatment, and when there was associated cutaneous dystrophy, resulted in exposure of the bone and severe functional and esthetic problems). A critical study of the radiotherapeutic techniques used suggests that the dose given should be reduced, the fields modified, and Cobalt used in preference to electrons in most cases.

Face

Predominant of exclusive orbital and facial involvement in infantile cortical hyperostosis (de Toni-Caffey's disease). Report of four cases and a review of the literature.

Four patients who presented with predominant or exclusive face and orbital involvement by de Toni-Caffey's disease are reported. Facial manifestations of infantile cortical hyperostosis may be the first and sometimes the only manifestion of the disease. A mandibular involvement is almost always present and its characteristic appearance leads to the diagnosis of de Toni-Caffey's disease.

Female

Maxillary African histoplasmosis mimicking malignant jaw tumour.

An account is given of an unusual presentation of solitary Histoplasmosis duboisii of the jaw simulating a malignant neoplasm. This report is of interest for two reasons; firstly, the rarity of such a presentation and secondly, the extensive search of the literature which has failed to produce another case. The rationale for our treatment is also briefly discussed.

Adolescent

Aneurysmal bone cysts of the jaws.

Two cases of aneurysmal bone cyst are recorded. In the first there is clinical evidence to suggest that the lesion had been present for an unusually long period while incomplete clinical records of the other also indicate an unusual history. Histologically both lesions show a paucity of giant cells. It is not possible to make significant observations on aetiology other than support the theory that the lesion arises as a result of altered haemodynamics.

Adult