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At least 19 recordsLinked to original sources
PubMed1977

The missed menstrual period.

The most likely cause of a missed menstrual period in a woman of childbearing age is pregnancy, stress, or the effects of the pill. If fear of pregnancy is the basis of the problem, simply reassuring the patient that menstrual extraction is available may bring spontaneous resolution.

Abortion, Induced↗
PubMed1979

[Results of a long-term clomiphene citrate therapy in women with normogonadotropic menstrual disturbanes (author's transl)].

A total of 72 pregnancies was achieved in 59 women with menstrual cycle disturbances (WHO Type II) by administration of clomiphene. 27 of these pregnancies (34.7%) occurred only after more than three courses of cloimphene. A secondary classification of the patients was based on the symptomatic severity of the menstrual disturbance. Clomiphene (100 mg) was administered on the fifth day after the onset of menstruation for five days, whereby in one or two cases up to 19 courses had to be given. The group consisted of women who had rejected HMG-HCG therapy because of the possibility of multiple pregnancy. 59 pregnancies went to full term; 2 tubal pregnancies and 11 cases of miscarriage were recorded. The commencement of pregnancy was evaluated and the time of ovulation and the length of the luteal phase determined in women requiring up to three courses of clomiphene and those requiring over three courses. The investigation demonstrates that clomiphene therapy can be successful even after more than six courses of the drug. Side effects are minimal.

Adult↗
PubMed1978

The effect of ibuprofen on the intrauterine pressure and menstrual pain of dysmenorrheic patients.

In 12 dysmenorrheic patients we examined the therapeutic action of the Prostaglandin-synthesis inhibitor: Ibuprofen, a non-steroidal analgesic agent. Ibuprofen highly significantly reduced the resting pressure (P less than 0.001), active pressure (P less than 0.001) and frequency (P less than 0.05) of cyclic activity of the uterus, as well as menstrual pain (P less than 0.001). Since these effects occurred after a single oral dose of 800 mg Ibuprofen, without side effects or complications, extensive field trials are recommended with this and other PG-synthesis inhibitors, to assess their therapeutic benefits.

Administration, Oral↗
PubMed1975

Evaluation of d-norgestrel 1.0 mg as a post-coital contraceptive.

Two hundred and ninety-eight women were followed for 2578 months (2739 'bleeding intervals') of treatment with d-Norgestrel 1.0 mg given as a post-coital oral contraceptive. Fourteen pregnancies were recorded (general failure rate, 6.5 per 100 woman/years); at least 6 of these patients did not miss any tablet (corrected failure rate, 2.8). The acceptability rates (life table method) were 0.58 and 0.40 after 6 and 12 months of follow-up. The most important medical reason for drop-out was cycle irregularities. The cycle pattern is deeply disturbed by this method of oral contraception.

Adolescent↗
PubMed1979

10-year survey of 485 sterilisations. Part I--Sterilisation or hysterectomy?

A survey was made of all sterilisations performed in an obstetric and gynaecological unit in Dunfermline in 1965-74 to determine the outcome and complications. Altogether 547 women were sterilised by the modified Pomeroy method, and 485 (88.7%) were interviewed and examined. No sterilisation was followed by serious complications, and the incidence of even minor complications was low (4.12%). There were no subsequent pregnancies. Altogether 57 women had to be referred for gynaecological operations in the years after sterilisation but only 18 of these had to have hysterectomies. At interview 59 women were found to have gynaecological symptoms (menstrual disorders in 46), and examination showed that 83 women had a gynaecological condition, which was in most cases unsuspected by the patient. Most of these conditions were minor but three women had carcinoma-in-situ of the cervix. Although 46 women suffered menstrual disorders after sterilisation 104 had done so at some time before the operation. These results therefore offer little support for the wider use of hysterectomy as a form of sterilisation.

Adult↗
PubMed1977

Dysfunctional uterine bleeding in adolescence.

Dysfunctional uterine bleeding is one of the most frequent urgent gynecologic problems of the adolescent. Its diagnosis is by exclusion. Dysfunctional bleeding is managed expectantly with the anticipation of ovulation, individualization of therapy and continuous observation. In severe cases, hormal hemostasis and 3 months of cyclic therapy are indicated. In a small percentage of patients dysfunctional bleeding may persist and be associated with serious chronic disturbances.

Adolescent↗
PubMed1977

Bromocriptine for induction of ovulation in normoprolactinaemic post-pill anovulation.

19 women with anovulation after discontinuing oral contraceptive agents and with normal plasma-prolactin concentrations were treated with bromocriptine. Ovulation and menstruation were restored in 9 of the 13 amenorrhoeic and 5 of the 6 oligomenorrhoeic patients. The success-rate (74%) indicates that bromocriptine is an effective treatment for post-pill anovulation in normoprolactinaemic women.

Adolescent↗
PubMed1979

[Comparative clinical investigation of oral contraceptives with different doses (author's transl)].

The investigation of four oral contraceptives with different doses in adolescent girls showed that bleeding disturbances occur more frequently with low-dose preparations at the beginning of treatment. Nevertheless, these disturbances should be considered indicative of lesser central suppression. For this reason adolescent girls -- especially those with still immature cycles -- should be treated chiefly with preparations having only a low inhibitory effect on the central endocrine system in order not to disturb the maturation of the cycle.

Adolescent↗
PubMed1977

Vascular changes in traumatic amenorrhea and hypomenorrhea.

Pelvic angiography was performed in 12 cases of amenorrhea and hypomenorrhea which developed following curettage of abortion and in the puerperium. Six cases of similar age and obstetric history with normal menstrual cycles served as control. Pelvic angiography revealed widespread vascular occlusion of myometrial arteries, in seven of the twelve cases. These findings account for the small amount of endometrium removed on diagnostic curettage in these cases as well as the greatly reduced menstrual loss. The poor obstetric history of the cases studied may well be due to this excessive vascular damage.

Adult↗