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Meaning, memory structure, and mental processes.

Although people experience little difficulty in recognizing printed words and comprehending sentences, they cannot do it instantaneously. Experimental psychologists have recently measured the speed of these mental processes by applying a reaction-time method. The method provides new data concerning the organization and retrieval of familiar semantic information in human memory. It has been found that close relations between the meanings of words help people to recognize and pronounce the words faster, especially when the words are hard to see because of visual distortions. Close relations between word meanings also facilitate the comprehension of some sentences, as indicated by how long a person takes to decide whether the sentences are true or false. The facilitation is not universal, however. When the relation between the meanings of two words must be analyzed carefully, their proximity may actually inhibit mental processing. These results, along with additional findings, support the hypothesis that human memory includes a semantic network that represents various categories of objects at distinct locations linked to specify their relations with each other. The memory structure probably influences a number of different mental processes that use it. One possible access route to the network is through a set of detectors designed to accumulate sensory information and signal the presence of particular words. There also appear to be processes for searching and comparing pieces of knowledge after a person finds the memory locations of designated categories. Further research using the reaction-time method may provide a more detailed inventory of what facts are retrieved directly from memory and what are computed from other stored information (36).

Humans

[Effect of caffeine on motor reactions and visual-mental processing time].

The effect of coffee without and with caffeine (200 mg) on the performance of "awake" respectively "fatigued" subjects was proved. 5 females and 7 males (22 to 32 years) were chosen for the cross-over double-blind study. Motor reaction time, visual-mental processing time, reading-speed and reading-errors were recorded. Further experiments under aggravated conditions were carried out. In the morning ("awake") caffeine increases the efficiency of all parameters excepted the reading errors. At night ("fatigued") the increase by caffeine is insignificant. Even in some subjects caffeine decreases the speed of reading and increases the number of errors. Under test-conditions, which were aggravated by strong acoustical disturbance, caffeine does not improve efficiency, compared with caffeine-free coffee. Overriding into the range of decreasing performance in spite of increasing central activity was not found under any test-condition.

Adult

Electrophysiological evidence for temporal overlap among contingent mental processes.

A series of studies assessed perceptual-motor transmission of stimulus information by measuring lateralization of movement-related brain potentials in a choice reaction task with no-go trials. When stimuli varied in shape and size, lateralized potentials on no-go trials suggested that easily recognized shape information was used to initiate motor preparation and that this preparation was aborted when size analysis signified that the response should be withheld. This indicates that movement preparation can begin once partial perceptual information about a stimulus becomes available, contrary to an assumption of fully discrete models of information processing. By contrast, when stimuli varied only in size, no evidence for preliminary response preparation was obtained, contrary to an assumption of fully continuous models but consistent with asynchronous discrete coding models (Miller, 1982, 1988).

Adult

[Clinico-experimental study of mental processes in men with HIV infection].

A total of 55 males aged 19.5 to 62 years who were infected with HIV were examined psychopathologically+ and neuropsychologically by A.R. Luria's methods. Twenty-one of these patients were homosexuals. Syphilis was recorded in 34.7% in this group. Lymphadenopathy was the major clinical sign of HIV infection. Symptoms of organic involvements+ of the central nervous system were revealed by a psychopathological method. Neuropsychological studies detected dysfunction of the right cerebral hemisphere, particularly in a group of homosexuals suffering from syphilis.

AIDS-Related Complex

An alternative view of the neurobiology of dreaming.

The author critiques the recently proposed activation-synthesis hypothesis about the origin and formation of dreams. Many findings do not support the new hypothesis that specific pontine physiological processes, rather than mental processes, instigate dreams and produce their distortion. First, dreaming often occurs in the absence of the pontine processes. Second, forebrain activity (which can have mental correlates) is crucial to the instigation and maintenance of dreaming sleep. Finally, activity of the proposed pontine dream generator, which is claimed to cause dream distortion, is not reliably accompanied by dream distortion.

Diencephalon

[Lateralization of mental functions at the subcortical level (according to material from stereotaxic surgery)].

In 26 patients with expressed signs of parkinsonism the authors studied the state of higher cortical functions prior to and following stereotaxic operations. The results of such studies point to a distinct connection between the changes of certain mental processes and the side of the operation. It was demonstrated that the subcortical structures of the left and right hemisphere participate in the mnestic function in different ways. The specificity and different directions of postoperative changes in the higher cortical functions may in the opinion of the authors speak in favour of a certain specificity in the contributed organization of mental processes on behalf of the subcortical structures.

Adult

Psychosomatic medicine--past, present, and future.

"Psychosomatic" is not part of the average person's vocabulary, and most educated laymen know the meaning of "psychophysiological" and "somatopsychic." Without having words for the process, everyone senses that mental processes can influence bodily functioning and, certainly, that the sick body can produce a sick mind. Many explanations have been offered for the mechanisms underlying these processes--theories ranging from the irrational and religious to the philosophical and scientific. Scientific interest in these processes has been a relatively recent development, originating perhaps a few decades ago. It is time to take inventory, to review and consider the scientific history of psychosomatic medicine and the current status of the field. It is also fascinating to speculate on the developments and ramifications of psychosomatic medicine in the future.

Forecasting

Language comprehension processes of mentally retarded children.

The strategies for sentence comprehension employed by a group of 18 severely retarded children were compared with those of a group of nonretarded children matched on MA. Using toys, the children acted out a series of simple active- and passive-voice sentences describing events that were either probable, improbable, or neutral with respect to semantic expectations. The retarded children tended to rely more on semantic expectations than did the nonretarded children. Retarded children whose MAs were less than 3 years did not take word order into account, but those of higher MA did use a word-order strategy. They assumed that the first noun in the sentence corresponded to the actor in the external situation.

Adolescent

The psilocybin-induced "state of drunkenness" in normal volunteers and schizophrenics.

The effects of the psilocybin, a psychomimetic substance, on mental junctioning were investigated in normal volunteers as well as in schizophrenics. The disturbances induced constitute a psychoneurotoxic syndrome--"a state of drunkenness"--of about four hours duration which develops in three distinct phases. The basic mental symptoms of this syndrome consist of disturbances of the apperception, sensory perception and emotion. A moderate impairment of egofunctioning or reality appraisal and an inability to integrate different mental processes are observed. The psychomotor behavior is mainly harmonized to the prevailing emotional state and to the experiences caused by perceptual alterations, in a lesser degree. These changes, according to our observations, are more severe and more "psychotic-like" in schizophrenics rather than in normals. Psychopathological analysis of these changes proves that the whole syndrome cannot be considered as related to the spontaneously triggered functional psychoses or to the organic ones and, therefore, the term "model-psychosis" according to our opinion, is unsatisfactory.

Attention

Erythrocyte ITP pyrophosphohydrolase deficiency in a psychiatric population.

A higher incidence of erythrocyte ITP pyrophosphohydrolase deficiency was found among a psychiatric population when compared to a nonpsychiatric group of subjects. Although the incidence was highest among schizophrenics, particularly those diagnosed as paranoid, the majority of the patients did not show such deficiency. The parallelisms between ITP pyrophosphohydrolase and hypoxanthine-guanine phosphoribosyl transferase deficiencies, both characterized by the lack of availability of IMP, and correlated to behavioral disorders, suggest that irregularities of hypoxanthine nucleotides may be implicated in abnormal mental processes.

Erythrocytes