[Mesocolonic liposclerosis: isolated lesion of the mesocolon?].
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A case of solid and papillary neoplasm of a mesocolonic ectopic pancreas in a 13-yr-old girl is presented. An 8-cm, well-encapsulated, and partly calcified tumor which protruded from the mesocolon was resected surgically. Histologically, the tumor showed either solid sheets or papillary arrangements (around the vascular core) of uniformly small cells with alpha 1-antitrypsin-positive cytoplasm. Some of the tumor cells had zymogenlike granules, suggesting acinar cell differentiation. At the base of this tumor, small pancreatic tissues (islet, acinar, and ductular cells) were detected in the mesocolonic tissue. Incidences of both ectopic pancreas outside the gastrointestinal wall and solid and papillary neoplasm of the pancreas are rare, and this is the first case reported in the literature.
A case of inflammatory malignant fibrous histiocytoma of the mesocolon is reported. The lesion presented as a right lower quadrant abdominal mass, located at the mesocolon, with obstructive symptoms and accompanied by a severe infestation by Trichuris trichiura. It had a benign histologic appearance and was considered initially as an inflammatory and necrotic process with severe tissue eosinophilia secondary to the severe parasitosis. The tumor relapsed 13 months later at the anastomotic site and the patient died. Diagnostic, prognostic and therapeutic aspects of this rare tumor are discussed.
Primary mesenteric liposarcoma is a rare neoplasm. We experienced a case of liposarcoma of transverse mesocolon. In our case, the examination of ultrasonography and CT scan revealed the tumor was solid and encapsulated. Preoperatively we suspected the tumor was malignant by the angiographic findings. Laparotomy revealed that the tumor was located in the transverse mesocolon and it could be removed easily. The histopathological diagnosis was myxoid type liposarcoma. It is said generally that liposarcoma is liable to recur after simple resection, therefore, we reconsider that we should have excised more extensively for this case. The patient is doing well without evidence of recurrence for 17 months after operation.
The authors report a case of mesenchymoma of the transverse mesocolon and analyse 50 cases of tumour of the transverse mesocolon found in the literature. They emphasise the diagnostic difficulties, the pathological characteristics and consider the surgical problems raised by these tumours.
Intramural perforation of the colon proximal to the rectosigmoid is a rare complication of the barium enema examination. We present a case in which air and barium entered the wall of the transverse colon, and then dissected through the transverse mesocolon during double-contrast barium enema in an asymptomatic patient with no known underlying colonic disease.
The tumor-promoting activity of the anthraquinone laxative danthron was studied by giving 3 groups of male rats a single subcutaneous injection of the colon tumor-inducing agent 1,2-dimethylhydrazine (DMH). After 1 week, the animals were fed diets containing 0, 600 or 2400 ppm of danthron for 26 weeks. Two other groups of rats were included in the study; one received no treatment while the other was given danthron only. Altogether 9 tumors were observed among animals given DMA with or without danthron. The incidence of colon tumors was higher in animals receiving DMH and danthron than in those given DMH only (5/60 vs. 0/30), but this difference was not statistically significant. The kidneys and lymph nodes of mesocolon were enlarged and showed a yellowish-red and brown discoloration, respectively. The pigment mostly displayed a PAS-positive reaction but contained no lipid as determined by several staining procedures. The available evidence suggests that the pigment is drug-derived.
A pediatric patient with malignant melanoma of the transverse mesocolon is reported. No cases of malignant melanoma occurring from the mesenterium have been previously reported in the literature.
Two cases of abnormal collection of fat in the abdomen are reported. One involved the omentum, the other involved the mesocolon. Both patients had few symptoms with strikingly similar radiological findings of increased radiolucency due to fat surrounding the small bowel.
A 14 yr old girl presented with a large cystic mass in the transverse mesocolon which was completely excised. Cystic lymphangioma was diagnosed, based on the specific histologic, immunoperoxidase and ultrastructural findings.
The authors discuss the literature data and analyse three personal cases. They show that inflammatory pseudotumors of the abdominal cavity, especially those arising from the mesocolon, are distinguished with great difficulty from true malignant tumors macroscopically. In none of their personal cases was the correct diagnosis established during surgery and extended or combined operations were carried out. The authors claim that interventions of a lesser volume can be undertaken only when skilled emergency biopsy of different areas of the new growth yields negative results.
The frequency of liver metastasis was analyzed in 1,558 patients with primary colorectal carcinomas. The highest frequency of liver metastasis occurred in carcinomas of the transverse colon (17%) and the sigmoid colon (15%), when compared to the other segments, such as the cecum (10%), ascending colon (9%), descending colon (6%), rectum (9%) and anal canal (0%). It would appear that carcinoma located in those segments of the human colorectum containing any portion of the mesocolon are more prone to metastasize into the liver.
Clear cell carcinoma was found in the sigmoid mesocolon of a 54-year-old woman, 6 years after the removal of all ovarian tissue. This tumor is of müllerian origin. In addition to the müllerian structures proper--the fallopian tubes, uterus, cervix, and upper vagina--a "secondary müllerian system" is present diffusely throughout the pelvis and lower abdomen. This case represents a tumor of the secondary müllerian system.
The association of polyposis coli, osseous and dental abnormalities with fibrosis of mesentery, mesocolon and retroperitoneal tissues is described in a black male. The prognostic significance of this association, rendering colectomy impossible, is stressed.
A solid and papillary neoplasm of a mesocolonic ectopic pancreas, 6 cm of diameter, was found by chance in a woman age 33 and resected surgically. The histologic study showed a well delimited tumor made up of uniform eosinophilic cells forming papillae, with solid and cystics areas. Pancreatic tissue was detected in the periphery of the neoplasm. The presence of ectopic pancreas with a solid and papillary tumor is extremely rare. We have only found one case in the literature (5).
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