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At least 19 recordsLinked to original sources

Carpal tunnel syndrome leads to significant bone loss in metacarpal bones.

The present study was designed to determine bone density modifications at the forearm and metacarpal bones in patients with carpal tunnel syndrome (CTS). Bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry at the one-third distal end and for the total of the radius-ulna, together with the third and fourth metacarpal bones, in 48 clinically and electrophysiologically diagnosed (18 unilateral and 15 bilateral) affected extremities in 33 premenopausal women (mean age 38.9 +/- 6.5 years) with CTS. BMD values for non-affected extremities were used as controls for comparison with affected extremities. Bone mass was decreased approximately 7% in the forearm region (P < 0.02) and 18% in metacarpal bones (P < 0.01) of the thenar atrophy associated group compared with controls. A significant correlation was observed between disease duration (mean duration 3.2 +/- 2.7 years) and the decrease in metacarpal bone density (r = 0.43; P = 0.004). This is the first clinical report of quantified bone loss in affected extremities in patients with CTS, and the results suggest the need for further studies to assess the clinical significance and morbidity of this pathology, especially in patients with thenar atrophy.

Adult↗

Osteonecrosis and spontaneous fractures following renal transplantation. A longitudinal study of radiological bone changes and metacarpal bone mass.

Seventy-seven renal transplant (RT) recipients were studied radiologically with regard to bone lesions and metacarpal bone mass, at the time of and after renal transplantation. An increased incidence of rarefaction of the spine, a reduced metacarpal bone mass and an increased frequency of subperiosteal erosions were found at the time of transplantation in RT patients who subsequently developed osteonecrosis or spontaneous fractures as compared with RT patients who did not develop these bone complications. During the years after RT an increase in rarefaction of the spine, in subperiosteal erosions, in soft tissue calcifications and a decrease in metacarpal bone mass were found in all patient groups.

Adolescent↗

Age-related changes in cortical bone in women: metacarpal bone mass measurement study.

The mechanism of age-related cortical bone loss was investigated in 229 Japanese women, 41-94 years of age, by metacarpal bone mass measurement. While no significant correlation was found between bone width and age, a significant increase in bone marrow width, and significant decreases in cortical bone density and total bone mass were observed in association with aging (P < 0.0001). There was a significant negative correlation between total bone mass and bone marrow width (r = -0.239; P < 0.0005), and significant positive correlations between both total bone mass and cortical bone density (r = 0.539; P < 0.0001) and cortical bone width (r = 0.839; P < 0.0001). The findings suggested that age-related cortical bone loss in middle-aged and elderly women resulted from two different factors; a decrease in cortical bone density caused by progression of intracortical porosity, and a decrease in cortical bone width as a result of bone loss on the endosteal surface. The latter had a greater influence on an age-related cortical bone loss than the former.

Absorptiometry, Photon↗

[Giant benign osteoblastoma of the first metacarpal bone. Late results of its removal together with the whole metacarpal bone].

A case that is a recurrence of the localization of the first described case: within the first metacarpal bone, has been presented in detail. The tumor was of enormous size, eliminating grip function of the hand. It was removed surgically together with the whole first metacarpal bone, which original borders could not be determined. In the place of the removed tumor, freeze-dried cortical-spongy bone was inserted. The follow-up at 5 years after operation revealed full healing of the graft, without any symptoms of tumor metastasis and excellent hand function.

Adult↗

Age-related changes in cortical bone in men: metacarpal bone mass measurement study.

Metacarpal cortical bone mass was measured in 507 healthy Japanese men aged 40-95 years, using a microdensitometer to determine age-related changes in cortical bone in these middle-aged and elderly men. Total bone mass showed a significant negative correlation with age (r = -0.281; P < 0.0001). While bone width showed no significant correlation with age, bone marrow width showed a significant positive correlation (r = 0.210; P < 0.0001), and cortical bone width and cortical bone density showed a significant negative correlation with age (r = -0.265; P < 0.0001; r = -0.268; P < 0.0001, respectively). On the other hand, cortical bone width and cortical bone density showed a significant positive correlation with total bone mass (r = 0.814; P < 0.0001; r = 0.474, P < 0.0001, respectively). These findings suggest that cortical bone mass decreases significantly with aging in middle-aged and elderly men, perhaps as a result of two factors - decreased cortical bone width, ie, cortical bone thinning due to bone loss at the endosteal side of the cortex, and decreased cortical bone density due to progression of intracortical porosity. Cortical bone thinning may influence age-related cortical bone loss more than decreasing cortical bone density.

Adult↗

[Quantitative evaluation of the relation between bone mass of the metacarpal bone and bone mineral content of the forearm in normal persons and patients with chronic renal failure before and after kidney transplantation].

Twenty-seven healthy normal subjects, 30 non-dialyzed patients with chronic renal failure, 25 hemodialyzed patients on chronic hemodialysis, and 54 renal transplant recipients were evaluated simultaneously with regard to a correlation between the bone mineral content of the forearm and the total cortical thickness and area of the second left metacarpal bone. A significant correlation was found between bone mineral content of the forearm and the cortical bone mass of the metacarpal bone in normal subjects and in the patient groups.

Adult↗

Evaluation of a tapered-sleeve transcortical pin to reduce stress at the bone-pin interface in metacarpal bones obtained from horses.

OBJECTIVE: To evaluate stiffness and bone-pin interface stress for a transcortical tapered-sleeve pin (TSP) that incorporates bilateral tapered sleeves over a transcortical pin. SAMPLE POPULATION: 14 third metacarpal bones (MCIII) collected from adult horses of various breeds. PROCEDURE: Each MCIII was cut in half to provide 2 test specimens. Pins (conventional and TSP) of 3 diameters (6.35, 7.94, and 9.50 mm) were inserted in specimens (3 specimens for each diameter and each type of pin). The test fixture simulated a typical sidebar-span skeletal fixation device for horses. Single cycle load-deflection tests were performed. Cyclic fatigue tests of TSP were performed to evaluate fatigue characteristics and stress conditions at the bone-pin interface. Maximum stress and strain were calculated, and results were compared with existing data on fatigue characteristics of bone. RESULTS: Significant increases in stiffness (load-deflection) and higher loads at yield point were detected for the TSP (stiffness for conventional 9.50mm pins, 4,500 N/mm; stiffness for TSP, 19,988 N/mm). Results of cyclic tests revealed a close correlation with existing data on fatigue characteristics. CONCLUSIONS AND CLINICAL RELEVANCE: The TSP described here is stiffer than conventional transcortical pins, and stress across the bone-pin interface is more evenly distributed. Use of this TSP should minimize major problems encountered during external fixation associated with the transcortical pin and bone-pin interface (ie, bone necrosis, infection of the pin track, pin loosening, and bone failure).

Animals↗

Indexes of bone mineral content on second metacarpal bone roentgenogram analyzed by digital image processing: a comparison with other bone mass quantifying methods.

A new photodensitometric technique (digital image processing, DIP) was performed to assess the bone mineral content of the metacarpal bone as a screening test for bone loss in 340 healthy or osteoporotic women as well as 35 steroid-dosed patients and 46 patients with chronic renal failure on hemodialysis. This procedure was compared with single photon absorptiometry and dual photon absorptiometry in terms of clinical value. Two bone mineral indexes, metacarpal index and sigma GS/D (the integrated bone mineral density of cortical and trabecular bone on a cross section in the middle of the second metacarpal bone), were equal to other methods in the quantification of decreases in bone mineral content due to aging in healthy or osteoporotic women. In addition, sigma GS/D was sensitive enough to detect decreases in bone mineral content in patients with vertebral fractures, on steroid therapy, and with chronic renal failure. Thus, sigma GS/D measured by DIP was shown to have clinical value as a tool in screening for decreased bone mineral content.

Absorptiometry, Photon↗

[Aneurysmal bone cyst of the fourth metacarpal bone--a case report].

Aneurysmal bone cysts of the hand skeleton are rare (only 3 to 4 % of all ABC; Tillmann and v. Torklus 1966 ) and require a differentiated treatment. In the presented case, the fourth metacarpal bone of the right hand was affected (Enneking stage 3). On account of its rapid growth, radical excision was performed and the resected metacarpal bone was replaced by a bicortical iliac crest graft. The bone graft healed in without complications, the functional result is satisfactory. On twelve-month follow-up there were no signs of relapse.

Adult↗

A fundamental study of a computed X-ray densitometry system for bone mineral measurement in the second metacarpal bone.

The effect of radiographic exposure factors such as the photographic film density, X-ray tube voltage, and focus-film distance on the indices of bone mineral obtained by computed X-ray densitometry (CXD), a newly developed X-ray microdensitometric system, was investigated. sigma GS/D, which corresponded to the bone mineral density divided the integrated bone mineral by the bone width of the second metacarpal bone, was influenced by these exposure factors, whereas MCI, which represented the ratio of the cortical bone to whole bone, was independent of them. Present results indicated that the focus-film distance between 85 and 115 cm, the X-ray tube voltage in 45-60 kV, and a photographic density of lower than 1.82-1.86 of the screen-film combination should be used to assess quantitatively bone mineral of the second metacarpal bone using the CXD system.

Absorptiometry, Photon↗

[Stabilized arthroplasty of the 5th metacarpal bone. A therapeutic proposal for the treatment of old fractures-luxations of the 5th metacarpal bone].

The goals of the surgical treatment of fracture-dislocations of the fifth ray are length restoration of the fifth metacarpal, release of impingement and preservation of the carpo-metacarpal mobility. Our technic of "stabilised arthroplasty" satisfies theoretically to these three goals. It consists in resection-arthroplasty of the base of the fifth metacarpal associated with stabilisation by arthrodesis between fourth and fifth metacarpal.

Adult↗

Comparison of alveolar bone loss, alveolar bone density and second metacarpal bone density, salivary and gingival crevicular fluid interleukin-6 concentrations in healthy premenopausal and postmenopausal women on estrogen therapy.

BACKGROUND: Osteoporosis is an age-related metabolic bone disease characterized by decreased mass and increased susceptibility to fracture. The literature suggests a relationship between oral bone loss and skeletal osteoporosis; however, most studies have produced conflicting results. The purpose of this study was to determine if a relationship exists among alveolar bone loss, alveolar bone density, second metacarpal density, salivary and gingival crevicular fluid interleukin 6 (IL-6), and IL-8 concentrations in premenopausal and postmenopausal healthy women receiving estrogen therapy. METHODS: Twenty-eight healthy women (aged 23-78) were evaluated for this study. A vertical bitewing and hand radiographs were taken, and the subjects were evaluated for the presence of active periodontitis. The bitewing and hand radiographs were digitized, and measurements were made from the cemento-enamel junction to the alveolar crest from both arches. Bone density was evaluated in the maxillary and mandibular alveolar process and at the mid-shaft of the second metacarpal. Percent cortical area and the moment of inertia measurements were also determined. Stimulated whole saliva was collected for a 5-min period using a cube of paraffin as a stimulant and was analyzed for total protein by a colorimetric reaction and IL-6 and IL-8 by ELISA. RESULTS: The results of the study showed that postmenopausal women on estrogen therapy had more alveolar bone loss, more missing teeth, and reduced alveolar and second metacarpal bone density than premenopausal women. In addition, postmenopausal women on estrogen therapy had higher salivary IL-6 concentrations than premenopausal women. Alveolar bone densities were also strongly correlated to second metacarpal densities. CONCLUSIONS: The results of the study suggest that changes in alveolar bone density and levels of bone resorptive cytokines in saliva may be secondary to changes in menopausal status. These changes may predispose loss of alveolar bone with resultant loss of teeth.

Adult↗

[Features of the structure of the metacarpal bones of athletes in different specialties].

Metacarpal bones have been examined in hand X-ray photos of 125 sportsmen at the age of 17-18 years who go in for swimming (dynamic loading on the hand) and competitive gymnastics (static loading on the hand). Under the effect of systematic trainings, which are connected with an increased loading on the hand, a number of morphological changes take place in the metacarpal bones. A prolonged loading of the dynamic character delays the synostosis process in the distal parts of the forearm bones and contributes to lengthening the I, III and IV and to widening the I-V metacarpal bones. As demonstrate decreasing indices of compactness in the swimmers, the widening diaphisis of the metacarpal bones occurs at the expense of dilatation of the medullary cavity. The static loadings result in a greater delay of the synostosis processes in the upper extremity parts mentioned, in a greater width of the I-III, V metacarpal bones in boy-gymnasts. The increased index of compactness demonstrates that the widening diaphysis of the metacarpal bones takes place at the expense of thickening of the compact substance and narrowing of the medullary cavity.

Adolescent↗

[Mini-invasive osteosynthesis in injuries of the metacarpal bones in children].

Injuries of the metacarpal bones in child and adolescent age are much less frequent than in adult age. Most frequently the IVth and Vth metacarpal bone are affected where paradoxically in the distal area metaphyseal fractures predominate over injuries of the physes. During the period between 1994-1998 on account of this injury in our department a total of 11 patients were treated by the method of miniinvasive osteosynthesis. In 7 instances treatment by means of a Kirschner wire was used in injuries of the base of the 1st metacarpal bone, incl. four cases where a physeal separation of the Salter-Harris II type was involved, once a physeal fracture of the Salter-Harris III type and twice a metaphyseal injury. In four patients the subcapital fracture of the metacarpal bone was transfixed. In all instances one implant was used. A total of 11 excellent results were recorded. In one injury of the 1st metacarpal bone slight restriction of movements in the metacarpophalangeal joint occurred. Miniinvasive osteosynthesis, if indicated, is a reliable and simple method with excellent results. A thin Kirschner wire which should be always inserted, avoiding adjacent joints, is a satisfactory implant.

Adolescent↗

[External stabilization of the metacarpal bones II to V. Anatomic-clinical study].

The four ulnar metacarpal bones are connected to each other at their proximal and distal ends by strong ligaments. The second and fifth metacarpal bones are the frame of the metacarpus. Surgically, this is of great importance. A fracture of these two bones often requires stabilization, whereas a fracture of the third and fourth metacarpal bones with intact ligaments seldom requires surgery except in cases of severe fragment dislocation. Using external fixation for these purposes it seems to be of utmost interest to define secure pintracks through the soft tissue. In an anatomical study using formalin fixed specimen it clearly could be demonstrated that the second and fifth metacarpal bones are best suited for external fixation. The second metacarpal bone should always be fixed from the radial side because the fixator pins can be inserted within a wide range of angles without the risk of violating the extensor tendons. Variations of tendons and ligaments are seldom located on the radial side of the second metacarpal bone and therefore, finger movement is unhindered after pin application. A similar consideration is true for the fifth metacarpal bone which should be fixed from the ulnar side. With respect to the extensor tendon which covers the entire dorsal surface of the fifth metacarpal bone, the angle of the pins should be 40 to 90 degrees from the dorsal side. For the third metacarpal bone, fixation from the radial side is preferable taking topographical and biomechanical considerations into account. The radial corridor to the fourth metacarpal bone is smaller than the ulnar corridor, but there is much less morphological variability of the extensor tendons than on the ulnar side where strong fibres often cross the fourth intermetacarpal space. Because in the proximal fourth of the metacarpal bones the tendons are located very close to each other, a small skin incision and preparation to the bone surface is advisable to exclude violation of the tendons when inserting fixator screws into the third and fourth metacarpal bones. Using formalin-alcohol fixed cadaver specimens for the research gives an idea of the anatomical situation in the dorsal metacarpus but cannot answer the question whether the tendons in the lax subcutaneous tissue of the living will automatically slip aside when the fixator pin approaches. This should be item to subsequent studies in fresh frozen specimens and follow-up studies in a larger amount of patients treated with external fixation.

External Fixators↗