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At least 19 recordsLinked to original sources
PubMed1976

A minicomputer-automated array spectrometer for liquid-chromatographic detection of metabolites.

A third-generation multiwavelength array spectrometer was developed as a detector for the high-resolution liquid-chromatographic characterization of metabolites. Components include a PDP-8/e minicomputer, matched pair of linear photodiode arrays, holographically-ruled gratings, fiber optics, flow cells, and high intensity xenon light source. The wavelength range is 256 nm differential with 1-nm resolution and can be adjusted from 200 to 800 nm. The system is capable of storing 20 spectra per second (200-456 nm) in a dual-beam mode. Special features include minicomputer-driven signal enhancement via integration as a function of signal strength. The display output includes presentation of the total absorption chromatogram vs. elution time in both real and post-run time as well as selectable single absorption band vs. elution time (post-run time). Application of this dedicated system is illustrated by the separation and charcterization of the metabolites of a carcinogen, 4-ethylsulfonyl-1 napthalenesulfonamide.

Animals↗
PubMed1986

Some remarks on computer-aided clinical electromyography based on experience with the Polish ANOPS minicomputer.

The author evaluates the application of the Polish minicomputer Analyser of Noise of Periodic Signals (ANOPS) in practical electromyography (EMG) and compares the diagnostic yield of ANOPS with that of manual quantitative EMG. The advantages of ANOPS--at least in the past--include speed, large samples, new data, reduced examiner bias, quantified evaluation of maximal effort record and online recording. The most important limitations of ANOPS are absence of complex potentials due to distortion of signals, loss of phase evaluation, and lack of comparability of amplitude with other methods. ANOPS is compared with other automated methods applied to evaluation of interference pattern and parameters of single motor unit potentials (MUPs). Most of the latter are based on pattern recognition. ANOPS does not meet all of the criteria which an automatic method should meet to be accepted in EMG practice. The most important problem is the distortion of properties of the EMG signal. Further search for computer-aided EMG methods and their careful testing in practice are necessary.

Computers↗
PubMed1988

Evaluation of a microcomputer-based clinical laboratory data acquisition system linked with a minicomputer-based patient data management system.

We describe a microcomputer-based clinical laboratory data acquisition system linked with a minicomputer-based patient data management system and report on its performance. The system consists of a microcomputer and six laboratory analyzers: a blood gas analyzer, a flame photometer, a plasma osmotic pressure meter, a chloride ion titrator, a blood sugar analyzer, and a hemoglobin concentration and saturation meter. With the addition of a previously developed microinterface unit to each laboratory analyzer, data from each analyzer can be automatically transmitted to the microcomputer through a communication network. These data are then automatically transmitted to the patient data management system and thereby become part of that data base. Performance of this system was evaluated in two ways: (1) by comparing the turnaround time from an anesthetist's order for a laboratory analysis to receipt of the analysis with the time required in a control situation and (2) by comparing the number of steps a laboratory technician is required to walk to obtain and deliver the laboratory result with the number of steps required in a control situation in which no system was used. The turnaround time and the number of steps walked using this system were 552 +/- 41 seconds (n = 19, P less than 0.001) and 197 +/- 31 steps, respectively (n = 19, P less than 0.001), contrasted with 622 +/- 52 seconds and 374 +/- 87 steps without the system.

Clinical Laboratory Information Systems↗
PubMed1979

Automated nerve fiber counting using an array processor in a multi-minicomputer system.

It has been suggested that recovery of motor and sensory function in the site distal to a peripheral nerve lesion should be improved if the nerve bundles (fasciculi) are matched and individually sutured. Three parameters are proposed to provide quantitative data: the count of the nerve fibers that regenerate, the number of functional regenerated nerve fibers, and a measurement of end organ reinnervation. A thin cross section of a transected and repaired sciatic nerve of a mongrel cat is fixed, stained, photographed, and digitized through a microscope 6 months following nerve repair. The data arrays are then subjected to four basic processing routines: edge enhancing, thresholding, template matching, and peak detection. Finally, the peaks are counted and provide an estimate of the number of nerve fibers in the nerve under study. Comparing counts of nerve fibers proximal and distal to the transection site of the nerve provide data on the proportion of regeneration present at various times. The content of this paper is, to a large extent, describing the implementation of the needed image-processing algorithms for automated counting on the Multi-MiniComputer System (MMCS). Optimal use of the AP-120B array processor and the pipeline processing provided by using the Eclipse 200s and the Nova 3 make a marked improvement in overall throughput.

Animals↗
PubMed1990

Adding a microcomputer bar-code network to a minicomputer-based radiology information system.

A bar-code terminal network under software control of a microcomputer was added to the minicomputer-based radiology information system at the Medical College of Georgia in Augusta. The bar-code network was specifically installed to address the inherent inaccuracies occurring when procedure information was entered at the time of registration before procedures were actually performed. Technologists now enter procedure data into bar-code terminals after procedures are performed, substantially reducing database errors. This approach allowed us to take advantage of a microcomputer product without the necessity of completely converting our highly customized information system software from mini-to microcomputer.

Electronic Data Processing↗
PubMed1985

A minicomputer approach to consultation-liaison data basing: Pedagog-Admin-CLINFO.

Minicomputer systems have been designed for researchers who have no prior computer experience and, therefore, require no computer training, that is, programming knowledge. Such systems allow immediate access to the data, their retrieval, reduction, and analysis, and the retention of direct control over the data base by the researcher. In addition, CLINFO offers a wide range of calculations and statistical procedures. The three-dimensional, time-oriented data-base format of CLINFO allows for a longitudinal study of a particular variable, and its repeated measure over time in the same patient. This system has been adapted for use in the consultation-liaison setting to provide pedagogic, research, and administrative functions from a field-tested data base.

Computers↗
PubMed1986

Analysis of fetal activity and maternal and fetal heart rate using a laboratory minicomputer.

Using a PDP-11 minicomputer, a system was developed for real-time acquisition of fetal breathing, body movement, and heart rate data. Analogue event pulses were input electronically to a DR-11 16 channel A/D, D/A interface and the event times were measured using an AR-11 real-time clock. Event times were stored for comprehensive off-line analysis and useful data summaries were also provided on-line. The on-line printouts enabled investigators to examine the quality of the data at the time of the study. The system has resulted in faster data acquisition and analysis and greater accuracy of measurement.

Computers↗
PubMed1990

[Determination of virus concentration using a minicomputer].

Described in this paper is a physical method by which to determine virus concentrations, including ultracentrifugation of a sample through a saccharose gradient and subsequent analysis of tubule content by means of a flow photometer. Here before, the curves thus obtained used to be graphically evaluated by means of stencil plates. Direct recording and processing of the extinction-time curve by means of a KC 85/1 minicomputer have substantially improved accuracy of results. Time consumption has been reduced, and reading as well as calculating errors have been entirely ruled out. Repetition of determinations confirmed that virus concentrations could be determined at an accuracy of four to seven percent.

Animals↗
PubMed1985

[Active rhinomanometry with a minicomputer and printer].

A rhinomanometer is described which is coupled with a minicomputer and printer. The experimental results can be presented on a monitor and printed out via the printer. Besides plottings of rhinomanograms it is also possible to print out V1.5 values, the side difference, the decongestion effect, and other data of the patients in tabular form. Several measurements of the same patient, e. g. before and after decongestion, can be plotted and compared simultaneously. A nozzle system or a mask can be used. The advantages for the clinical application of this automatic computer system are described.

Adult↗
PubMed1979

[Quantitative echocardiography using a minicomputer (author's transl)].

Echocardiography should not remain merely qualitative but every effort should be made to make it quantitative, providing the clinician with numerical values. Three items are necessary: a graphic table, a minicomputer and an electronic reprograph, all small in size. The tracings obtained in TM technique are digitalised using the graph table, and the computer provides the results in the form of listings and graphs. The latter are of two types: --some are used for the analysis of the respective chronology of the various phenomena: left ventricular diameter and its normalised derivative, apexocardiogram or carotid pulse, movement of the greater cusp of the mitral valve, thickness of the myocardium, heart sounds; --the others are used for study, with the aid of an X-Y representation in the form of loops, of variations in one phenomenon in relation to the other. Deformation of such loops makes it possible to detect poor synchronisation between 2 phenomena.

Computers↗
PubMed1975

Operant conditioning and behavioral analyses using a minicomputer.

An operant conditioning and data analysis software system was developed for use on a PDP-12A minicomputer. The operant software functions in quasi time-sharing fashion to control and acquire data from any peripheral device that operates in the binary mode. In addition to independently running different experiments in near simultaneous fashion, the program also provides information on the current status of each experiment using a cathode ray-tube display. Response data from each experimental subject is stored on magnetic tape and analyzed, off-line, by the data analysis portion of the software system. A discussion of the operation of this system is given for one possible application: visual discrimination training.

Animals↗
PubMed1978

A minicomputer system for display and rate analysis in vectorcardiography.

A system has been constructed for recording vectorcardiographic signal with a FM taperecorder. Off-line AD-conversion and analysis of rates and magnitudes of partial vectors are made with a minicomputer. The reason for studying particularly initial vectorrates is that according to our hypothesis these contain valuable information for classification of certain cardiac arrythmias according to supraventricular or ventricular impulse focus. Preliminary results confirm the hypothesis. In vectorcardiography one difficulty is to give an easily comprehensible presentation of the vectorloop. In this study a method for '3-dimensional' display has been developed, using a graphic display processor and varying intensities of the beam. The system is to a high degree man-machine interactive.

Arrhythmias, Cardiac↗
PubMed1978

An approach for physiological signal processing by laboratory minicomputer.

Physiological signal-processing instrumentation including the digital oscilloscope is becoming more dependent upon the microprocessor. Minicomputer software has been developed which demonstrates data-processing approaches that should be considered for incorporation into the firmware of digital oscilloscopes. This core-resident software called DATAC operates in an interpretive mode and provides such features as digital signal editing, filtering, and basic processing including differentiation and integration.

Computers↗
PubMed1979

[Results of employing single crystal gammacamera and minicomputer in the first tracer passage to determine left-ventricular ejection fraction and wall motion (author's transl)].

Single crystal gammacamera and minicomputer were employed in 71 patients to determine left-ventricular ejection fraction (EF) (17 mCi 99mTc-HSA; 30 degrees RAO projection) by means of the first tracer passage. In 30 out of these patients, ventricular wall motion could be analyzed additionally because later on the gammacamera was equipped with a converging collimator. Comparison with cineventriculographically determined EF values revealed a good correlation (r = 0.91), not depending on left-ventricular wall motion pattern. Hereby, with first transit, high EFs were computed somewhat lower and low EFs were found somewhat higher. This non-limiting discrepancy is closely related to the influence of paracardiac "background"-radioactivity. Comparative analysis of segmental wall motion demonstrated agreement in 83% of the 90 segments examined. Therefore, it can be confirmed that performance of the first tracer passage for a evaluating segmental wall motion must not mandatorily be done with a multicrystal camera.

Adult↗
PubMed1975

Optimization of dose distributions in moving-strip therapy using a minicomputer.

Optimized 60-Co dose distributions for the moving-strip technique were calculated for 3 patients using a PC-12 minicomputer program which corrects for field obliquity and changes in patient thickness. Beam profiles were measured using an ionization chamber in a water phantom. A Masonite phantom was constructed to simulate a patient and used to measure optimized and unoptimized midplane dose distributions by thermoluminescent dosimetry. Measured midplane doses agreed with computer-calculated doses within experimental error. The computer optimization technique improved dose uniformity, reducing the midplane dose variation from plus or minus 12-13% to plus or minus 3-4%.

Cobalt Radioisotopes↗
PubMed1979

A study of the multiple pinhole coded aperture and the application of the minicomputer in image decoding.

Research has been done on optically reconstructed imaging employing the Multiple Pinhole Coded Aperture (hereafter abreviated as MPCA) in radioisotope tomographic imaging. However, problems remain in the optically reconstructed image method. Therefore, we employed a minicomputer (hereafter abbreviated as CPU) and developed the software for decoding and managing the radioisotope tomographic image. Combining the MPCA and the CPU system, we were able to decode and manage the radioisotope tomographic image. 1) In comparison to the optically decoded MPCA image, various input commands are possibly in the CPU method according to the dialogue between the CPU and the on line typewriter. In addition to this, decoded tomographic images of unrestricted depth are readily attainable. 2) In the CPU method noise elimination and other aspects of image management can be easily performed.

Computers↗