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[Mitral valve insufficiency due to ballooning. A surgical series of 70 cases].

The authors report 70 cases of mitral regurgitation due to ballooning. For the surgeon this is the most frequent cause of degenerative mitral regurgitation in patients around 60-years-old. The aetiology still remains unknown. There are two opposing theories--the congenital and the acquired. The appearances at operation are characteristic--a localised or diffuse ballooning of one or both cusps with elongation of the chordae attached to the ballooned portion. Two histological features are noted--myxomatous degeneration of the cusp and the absence of any inflammatory process. Ballooning may be asymptomatic and bening for a long time before evolving progressively or suddenly into important mitral regurgitation. The pre-operative diagnosis is aided by left ventricular angiography and echocardiography. Surgical treatment, guided by the findings at operation, usually involves mitral valve replacement or, less frequently, mitral valve repair.

Adult

[Echocardiographic diagnosis of rheumatic mitral valve insufficiency].

Echocardiography was used for the examination of 45 patients with rheumatic mitral valve insufficiency. Echocardiographic data were found to permit making the diagnosis of mitral valve disease and differentiating within the group of mitral valve disease as such. A mitral disease with prevailing insufficiency is characterized on an echocardiogramme by a unidirectional diastolic movement of thickened mitral cusps, by an increased general excursion of the mitral valve, dilatation of the left ventricular cavity, increased systolic excursion of the ventricular septum, and a significant dilatation of the left atrial cavity. "Pure" mitral insufficiency is characterized by a dilatation of the left heart, vari-directional movements of the mitral cusps during the diastole, and a marked lack of their closure during the systole.

Adolescent

[Echocardiographic diagnosis of mitral valve insufficiency].

Seventy-two persons with various forms of mitral insufficiency of rheumatic and non-rheumatic etiology and 17 healthy individuals (control group) were examined. The results of echocardiography in 35 patients were compared with operative (mitral commissurotomy, valve plastics) findings. Several typical variants of a mitral echogram in patients with "pure", predominant and concomitant mitral insufficiency were distinguished. The predominantly "valvular" mechanism of mitral insufficiency in patients with rheumatic disease and the predominant role of "subvalvular" pathology in nonrheumatic insufficiency were revealed. The diagnostic value of determining the indices of cardiac activity and the size of the left parts of the heart by means of echocardiography is confirmed.

Echocardiography

[Cytochrome system of myocardial mitochondria in patients with mitral valve insufficiency].

The content of cytochromes in the mytochondria of the papillary muscles and auricles of the left atria was studied by means of differentiated spectrophotometry in patients operated on for mitral valve insufficiency. A significant reduction of all cytochromes was noted in the papillary muscles of the left ventricle that depended on the stage of circulatory insufficiency. In cases of a protracted course of the disease a tendency towards a reduction in the content of all cytochromes, especially the a + a3 cytochrome, was noted in the papillary muscle. When the content of cytochromes in the myocardium was reduced, the number of cardiac complications in the postoperative period was much higher. A moderately expressed activity of the rheumatic process had no significant effect upon the content of cytochromes in the heart muscle.

Adolescent

[Atrial spetal defects of the ostium secundum type with mitral valve insufficiency. Apropos of 31 cases].

31 cases of ASD with mitral incompetence have been reviewed. The aetiology of the mitral incompetence is most frequently congenital, contrary to the classical view. The usual mitral defect is a combination of gaping of posterior commissure with a narrow valvular opening. The usual angiocardiographic picture is one of prolapse of the mitral valve. One of the characteristic findings, which has already been reported in the literature, is of redundant valve tissue, with myxomatous degeneration (one case confirmed histologically). Surgery is indicated in every case. Conservative mitral surgery gives satisfactory results in the mid-term.

Angiocardiography

[Analysis of the hemodynamics in patients with artificial mitral valve insufficiency].

Hemodynamic disorders which developed in 12 patients with artificial mitral incompetence were studied. A method developed in the clinic of analysing the findings of catheterization and cine-angiocardiography was used. The method of analysis of single-plane ventriculograms makes it possible to estimate the volume of blood regurgitated into the left atrium to an accuracy of several millilitres. The degree of artificial incompetence is determined from the relative regurgitation which is estimated by dividing the volume of returned blood flow by the total volume of ventricular ejection. It is concluded that the "malignancy" of the course of artificial incompetence is determined by a sharp reduction of the effective cardiac output (to 33--50% of the normal volume) against the background of rapid rapid exhaustion of the left ventricular myocardum.

Cardiac Catheterization

[Indices of left venticular performance and evaluation myocardial quality in mitral valve insufficiency, chronic aortic valve insufficiency and stenosis].

132 patients with pure mono-valvular cardiopathies (mitral incompetence, aortic stenosis and aortic incompetence) were classified into two groups according to the values of the systolic work index/myocardial mass ratio (SWI/MLV). Normal values of the ejection function (EF) and mean velocity of circumferential fibre shortening (VCF) for each cardiopathy were so obtained. Only patients with aortic stenosis of group I (SWI/MLV greater than or equal to 0.75 gm . g-1) had normal EF. All the other patients had EF and VCF values below normal although this did not always imply impaired myocardial function. Therefore the myocardial mass should also be considered in the evaluation of myocardial function and it would seem desirable to take this parameter into account in the management of these patients.

Adult