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At least 19 recordsLinked to original sources

Effect of race and musculoskeletal development on the accuracy of air plethysmography.

PURPOSE: The purpose of this study was to determine the effect of race and musculoskeletal development on the accuracy of estimates of body fatness (%fat) via air displacement plethysmography (AP). METHODS: Estimates of %fat were made via AP, hydrostatic weighing (HW), dual-energy x-ray absorptiometry (DXA), and the criterion, a four-component model (4C) in 64 black (B) and white (W) men, who were either resistance trained (RT) or served as controls (C). RESULTS: Based on a three-way ANOVA, there were no statistically significant three-way or race x musculoskeletal development interactions. There was no main effect of race on the validity of estimating %fat by AP; the mean bias between %FatAP and %Fat4C was similar for B (3.6% body fat) and W (3.7%). In addition, the density of the fat-free mass (Dffm) for B (1.098 +/- 0.002 g x mL) was not different than 1.10 g x mL. There was a significant effect of musculoskeletal development on the validity of the estimation of %fat from AP; the mean difference in %fat between %FatAP and %Fat4C was less in RT (1.5% body fat) than in C (5.3%), but a large SEE of 5.5% was observed for RT. A significant (P < 0.05) correlation was found between the mean bias between methods and body volume (-0.44) and mesomorphy (-0.55). CONCLUSIONS: Race does not affect the accuracy of estimating %fat by AP. Race-specific equations estimating %fat via densitometry (e.g., AP, HW) such as the Schutte are not justified, because Dffm is not greater than 1.10 g x mL. Estimation of %fat via AP is more accurate in larger individuals with high musculoskeletal development as a group, but individual results are highly variable.

Absorptiometry, Photon↗

Effect of musculoskeletal development on the prediction of body density in females.

The purpose of this study was to determine if musculoskeletal development had a significant effect on the prediction of body density in females. Subjects consisted of 156 females aged 17 to 44 years. Subjects were divided into three groups on the basis of musculoskeletal development as determined by the Heath-Carter Anthropometric Somatotype mesomorphy rating. Anthropometric measurements included eight skinfold measures (tricep, subscapula, chest, midaxillary, abdomen, suprailiac, thigh, and calf), body diameters of the humerus and femur, and circumferences at five locations (waist, forearm, upper arm, calf, and gluteal). Residual lung volume was determined by the closed circuit oxygen dilution method prior to the measurement of body density by hydrostatic weighing. A regression equation was developed to predict body density from the sum of seven skinfolds, sum of seven skinfolds squared, age, and mesomorphy rating. A similar regression equation was developed using the sum of three skinfolds, sum of three skinfolds squared, and the other variables. Results indicated that mesomorphy rating did not contribute significantly to the prediction of body density in females. It was concluded that musculoskeletal development did not have a significant effect on the prediction of body density in females.

Adolescent↗

Profiles of musculoskeletal development in limbs of college Olympic weightlifters and wrestlers.

To investigate the event-related profiles of musculoskeletal development in weight-categorized athletes, we measured the cross-sectional areas (CSA) of bone and muscle in the forearm, upper arm, lower leg and thigh, using a B-mode ultrasound apparatus, in college Olympic weightlifters (OWL, n = 19) and wrestlers (WR, n = 17) and untrained men (UM, n = 24), whose body masses were within the range from 55 kg to 78 kg. Both bone and muscle CSA at all sites were significantly correlated to the two-thirds power of fat-free mass (FFM(2/3)) with correlation coefficients of 0.430-40.741 (P < 0.05) and 0.608-0.718 (P < 0.05), respectively. Moreover, there were significant correlations between bone and muscle CSA at all sites (r = 0.664-0.829, P < 0.05). Even when bone and muscle CSA were expressed relative value to FFM(2/3), both OWL and WR showed significantly greater values than UM at all sites except for the lower leg. Furthermore, the comparison of the lean (bone + muscle) CSA ratio from site to site indicated a higher distribution of lean tissues in the upper extremities in OWL and WR compared to UM. While there was no significant difference between the two athlete groups in FFM(2/3), OWL showed significantly larger values than WR in the bone CSA of the upper arm and thigh and in the muscle CSA of the lower leg and thigh. However, lean CSA ratios of the upper extremities to the lower ones were significantly higher in WR than in OWL. Thus, the present results indicated that, compared to UM, OWL and WR had a greater lean tissue CSA in limbs, especially in the upper extremities, even when the difference in FFM was normalized. Moreover, the relative distribution of lean tissues in limbs differed between the two weight-categorized athletes in spite of there being no difference in FFM, which may be attributable to their own training regimens and/or competition style.

Adult↗

Fetal programming of body composition and musculoskeletal development.

The prevalence of obesity, sarcopenia and osteoporosis is rising and there is increasing interest in determinants operating in early life. Fetal programming is the phenomenon whereby alterations in fetal growth and development in response to the prenatal environment have long term or permanent effects. Evidence for fetal programming of body composition and musculoskeletal development comes from epidemiological studies, investigation of the role of early undernutrition and preliminary findings on underlying mechanisms. Low birth weight and poor prenatal nutrition are associated with changes in adult body composition including altered fat distribution, reduced muscle mass and strength, and low bone mineral content. The mechanisms include a direct effect on cell number, altered stem cell function and resetting of regulatory hormonal axes. The next stage is translation of these findings into testable preventive strategies to maintain optimum body composition and minimize the risk of obesity, sarcopenia and osteoporosis in later life.

Body Composition↗

Musculoskeletal development: a review.

The early development of the limbs, the skeletal and muscular systems, and the joints and early changes in joint mobility are reviewed. The musculoskeletal system is vulnerable to failures of specific morphogenetic processes in the embryonic period. Congenital anomalies and postural deformities also may arise in the fetal period. Awareness of prenatal and postnatal events and their timing will assist health care workers in management of pediatric clients.

Fetal Movement↗

Developing musculoskeletal education programs for physicians and the general public: findings from a needs assessment.

OBJECTIVE: To assess the educational needs and learning preferences of primary care physicians and the general public in receiving musculoskeletal health education. METHODS: Prospective surveys were mailed simultaneously to 2,250 primary care physicians and 2,250 members of the general public. The surveys included questions about demographics, motivation for attending programs, and preferred education program formats. RESULTS: The 68 responding physicians attend continuing medical education programs mainly based on topics, speakers, and timing. They prefer lectures and find question and answer sessions least helpful in supporting learning. The 96 responding members of the general public attend programs mainly based on topics, speakers, and fees. The general public stated that question and answer sessions best support learning in programs. A large percentage of responding physicians provide health education to their patients, but a small percentage of the general public respondents stated that they receive health education from physicians. DISCUSSION: Responses from physicians and the general public were generally not surprising but revealed interesting contrasts between learning preferences. While physicians and the general public both value speakers and topics, the physicians want to increase their knowledge about disease, whereas the general public wants practical information. Physicians and the general public also appear to take different approaches to learning. The contrast between availability and provision of health education is also striking. We cannot generalize our results with absolute confidence because the return rates for the surveys were so low. Nonetheless, we support the need to educate physicians and the general public in ways that match their preferred learning methods and educational needs.

Adult↗

Are occupational drivers at an increased risk for developing musculoskeletal disorders?

STUDY DESIGN: This study analyzed the role of exposure to driving and other covariates in reports of back, neck, and shoulder pain and resultant disability. Cohorts in Sweden and the United States were compared. OBJECTIVES: To establish the effect of mechanical and psychosocial factors in reporting back, neck, and shoulder pain and work loss. SUMMARY OF BACKGROUND DATA: There are numerous reports of a positive relationship between back pain and driving. However, exposure data are minimal. The influence of job satisfaction has not been assessed. METHODS: The physical factors affecting reports of back, neck, and shoulder pain were investigated in a two-country cohort study of bus and truck drivers and sedentary workers. Vibration exposure was obtained by directly measuring the vibration imposed on the driver during a typical work day. Lifting exposure was attained by questionnaire. Cumulative exposure was computed based on work history. Musculoskeletal health information was based on a modified nordic questionnaire, and other questionnaires recorded the physical and psychosocial aspects of the work environment. RESULTS: Of the sample, 50% reported low back pain, with no difference between countries. The highest risk factors (odds ratios) for back and neck pain were long-term vibration exposure, heavy lifting, and frequent lifting. A combination of long-term vibration exposure and frequent lifting carried the highest risk of low back pain. Work loss from low back pain was influenced by perceived job stress. CONCLUSIONS: Vibration (resulting from driving) and lifting cause back, neck, and shoulder pain, whereas inability to work seems affected by stress at work.

Adult↗

[Ergonomic analysis of nursing activities in relation to the development of musculoskeletal disorders].

Musculoskeletal disorders are frequent among nurses. The literature so far focused mainly on back pain while paying little attention to disorders of the upper and lower limbs. Back pain is associated to patients' handling, but we know very little on the effect of awkward postures due to frequent bending and twisting and of work organisation which could also be involved in the genesis of these disorders. The pain localised to the musculoskeletal apparatus, including the presence of multiple complaints, was studied in a group of 70 nurses, with Estev and Vistat questionnaires, together with the possible association to work conditions. An ergonomic analysis of nursing activities (the postures and cognitive workload) was carried out to uncover associations to the risk of developing musculoskeletal disorders. Results show an involvement of all musculoskeletal sites and a high prevalence of multiple pain complaints (54% of the nurses). Ergonomic analysis highlighted the adoption of awkward postures for prolonged times. Moreover, nurses are frequently interrupted and their working pace is under continuous time pressure. Cognitive workload and work organisation should also be addressed, besides the postures, as factors which could compromise the health of nurses and influence the quality of care.

Ergonomics↗

Aging, long-distance running, and the development of musculoskeletal disability. A controlled study.

Four hundred ninety-eight long-distance runners aged 50 to 72 years were compared with 365 community control subjects to examine associations of repetitive, long-term physical impact (running) with musculoskeletal disability and medical service utilization in a cross-section study. Runners had less physical disability than age-matched control subjects (p less than 0.01) and maintained more functional capacity (p less than 0.001) as measured by a modified Health Assessment Questionnaire Disability Index. Runners sought medical services less often, but one third of the visits that they did make were for running-related injuries. No differences were found between groups in conditions thought to predispose to osteoarthritis and musculoskeletal disability. Ligamentous laxity and family history of arthritis were similar in both groups. Runners demonstrated better cardiovascular fitness and weighed less. Differences persisted after adjustment for age, occupation, and sex, and after inclusion or exclusion of subjects with major medical problems. Musculoskeletal disability appeared to develop with age at a lower rate in runners (0.003 units per year versus 0.028) than in community control subjects, and the decreased rate was observed with both lower extremity and upper extremity functions. These data suggest positive effects of systematic aerobic running activity upon functional aspects of musculoskeletal aging.

Aged↗

Working hours as a risk factor in the development of musculoskeletal complaints.

The length of daily working hours as a risk factor for the development of musculoskeletal complaints was studied by comparing the sick leave statistics of 408 sewing machine operators on full-time schedules (8 h working day) with 210 operators on part-time schedules (5 h working day). Working part-time was shown to postpone the occurrence of sick leave due to musculoskeletal disorders by approximately half a year. There was no lasting effect on the reduction in working hours on sick leave due to shoulder-neck complaints, but a reduction in low back complaints was indicated. It is suggested that any reorganization of work activities to counteract musculoskeletal injuries from repetitive work should aim to break up the muscular activity patterns over time periods considerably shorter than the 5 h working day of the part-time workers in the present study.

Absenteeism↗

Density of the fat-free mass and estimates of body composition in male weight trainers.

The purpose of this study was to determine whether the assumed density and composition of the fat-free mass (FFM) and estimates of percent fat (%Fat) from body density by use of the Siri equation (%Fatd) are valid in weight trainers with high musculoskeletal development. Measures of body density by underwater weighing (Db), body water by deuterium dilution, and bone mineral by whole body dual-energy X-ray absorptiometry were obtained in young white men: 14 weight trainers with high musculoskeletal development and 14 non-weight-training controls with average musculoskeletal development. %Fatd was significantly higher (P < or = 0.05) than %Fat estimated from body density, water, and mineral (%Fatd,w,m) by use of a four-component model in weight trainers (17.3 +/- 4.6 vs. 13.2 +/- 5.1%) but not in controls (14.8 +/- 3.1 vs. 14.2 +/- 3.6%). The greater discrepancy between %Fatd and %Fatd,w,m was explained by lower density of fat-free mass (Dffm) in weight trainers (1.089 +/- 0.005 g/ml) than in controls (1.099 +/- 0.007 g/ml). The lower Dffm in the weight trainers was due to higher water (74.8 +/- 1.2 vs. 72.6 +/- 20%) and lower mineral (5.3 +/- 0.6 vs. 5.9 +/- 0.4%) and protein (19.9 +/- 1.4 vs. 21.5 +/- 1.9%) fractions of the FFM. We conclude that, in young white men with high musculoskeletal development, Dffm is lower than the assumed value of 1.1 g/ml and %Fat is overestimated from Db by use of the Siri equation.

Adult↗

The health of the human skeletal system for weight bearing against gravity: The role of deloading the musculo-skeletal system in the development of musculoskeletal injury.

Musculo-skeletal disease is a major health problem which continues to increase in developed countries. A mechanism related hypothesis is presented to explain why most musculo-skeletal injury has an insidious onset and is not linked to a single traumatic event. The hypothesis predicts a close link between a dysfunction in the antigravity muscle system, which protects joints from injury, and the development of musculoskeletal disease patterns.

Journal Article↗

Future and new developments in musculoskeletal ultrasound.

Improvements in high-resolution gray-scale imaging and clinical expertise performing musculoskeletal ultrasound will undoubtedly continue. Development of digital beam formers, two-dimensional arrays along with exploitation of nonlinear techniques to achieve higher resolution and use of ultrasound contrast to improve flow sensitivity will all contribute to the utility of ultrasound in the musculoskeletal system. It behooves the radiologic community to become familiar with these techniques, not only for economic reasons, but also because of the rich complement of future applications of this modality. The few potential applications mentioned here may only scratch the surface of what is possible. In addition to improved images of tissue morphology, ultrasound may play a role in functional and quantitative assessment of soft tissues. It may likewise play a role in the evaluation of prosthetic implants, bone mineralization, and cartilage integrity. Thus, the role of this modality in future musculoskeletal applications may significantly impact clinical diagnosis and therapy.

Humans↗

Muscularity and the density of the fat-free mass in athletes.

The purpose of this study was to use estimates of body composition from a four-component model to determine whether the density of the fat-free mass (D(FFM)) is affected by muscularity or musculoskeletal development in a heterogenous group of athletes and nonathletes. Measures of body density by hydrostatic weighing, body water by deuterium dilution, bone mineral by whole body dual-energy X-ray absorptiometry (DXA), total body skeletal muscle estimated from DXA, and musculoskeletal development as measured by the mesomorphy rating from the Heath-Carter anthropometric somatotype were obtained in 111 collegiate athletes (67 men and 44 women) and 61 nonathletes (24 men and 37 women). In the entire group, D(FFM) varied from 1.075 to 1.127 g/cm3 and was strongly related to the water and protein fractions of the fat-free mass (FFM; r = -0.96 and 0.89) and moderately related to the mineral fraction of the FFM (r = 0.65). Skeletal muscle (%FFM) varied from 40 to 68%, and mesomorphy varied from 1.6 to 9.6, but neither was significantly related to D(FFM) (r = 0.11 and -0.14) or to the difference between percent fat estimated from the four-component model and from densitometry (r = 0.09 and -0.16). We conclude that, in a heterogeneous group of young adult athletes and nonathletes, D(FFM) and the accuracy of estimates of body composition from body density using the Siri equation are not related to muscularity or musculoskeletal development. Athletes in selected sports may have systematic deviations in D(FFM) from the value of 1.1 g/cm3 assumed in the Siri equation, resulting in group mean errors in estimation of percent fat from densitometry of 2-5% body mass, but the cause of these deviations is complex and not simply a reflection of differences in muscularity or musculoskeletal development.

Adipose Tissue↗

[Evaluation of individual predisposition to development of musculoskeletal system diseases].

A technique was worked out on the basis of studying of physiological indices of the main and medical aid appealability concerning musculoskeletal system diseases (MSD), physical examination of workers. It will allow for certain determine the character of individual predisposition to the development of the disease and in 84% of the cases rather sooner predict the disease if a worker has high individual predisposition and in 55.2% of other cases. Combination of tension and pain sensitivity indices measuring up 21-80 and 1.1 mm and more; 81-160 and 1.0 mm and more; 161-220 and 0.9 mm and more; 221-300 and 0.8 mm and more; 301 and more, 0.7 mm and more accordingly characterize high individual predisposition; less 50 and 0.5 mm--tolerance to the disease. A risk of the development of musculoskeletal system diseases conditioned by individual predisposition from the mathematical analysis happened in 16.2%. Application of the method before receiving the job can both reveal individual predisposition to musculoskeletal system diseases and prevent from harmful industrial conditions. It will decrease a risk of the development of MSD, keep sound health and prolong professional activity.

Disease Susceptibility↗

Wnts and wing: Wnt signaling in vertebrate limb development and musculoskeletal morphogenesis.

In the past twenty years, secreted signaling molecules of the Wnt family have been found to play a central role in controlling embryonic development from hydra to human. In the developing vertebrate limb, Wnt signaling is required for limb bud initiation, early limb patterning (which is governed by several well-characterized signaling centers), and, finally, late limb morphogenesis events. Wnt ligands are unique, in that they can activate several different receptor-mediated signal transduction pathways. The most extensively studied Wnt pathway is the canonical Wnt pathway, which controls gene expression by stabilizing beta-catenin in regulating a diverse array of biological processes. Recently, more attention has been given to the noncanonical Wnt pathway, which is beta-catenin-independent. The noncanonical Wnt pathway signals through activating Ca(2+) flux, JNK activation, and both small and heterotrimeric G proteins, to induce changes in gene expression, cell adhesion, migration, and polarity. Abnormal Wnt signaling leads to developmental defects and human diseases affecting either tissue development or homeostasis. Further understanding of the biological function and signaling mechanism of Wnt signaling is essential for the development of novel preventive and therapeutic approaches of human diseases. This review provides a critical perspective on how Wnt signaling regulates different developmental processes. As Wnt signaling in tumor formation has been reviewed extensively elsewhere, this part is not included in the review of the clinical significance of Wnt signaling.

Animals↗

Musculoskeletal ultrasound--a state of the art review in rheumatology. Part 1: Current controversies and issues in the development of musculoskeletal ultrasound in rheumatology.

As we begin the 21st century, musculoskeletal ultrasound (MSUS) is routinely used by an increasing number of rheumatologists throughout Europe and there is a growing interest in the application of MSUS in rheumatological practice in the UK. MSUS allows high-resolution, real-time imaging of articular and periarticular structures and has the advantages of being non-radioactive, inexpensive, portable, highly acceptable to patients and repeatable. There are a number of critical issues that need to be addressed in order to develop the role of MSUS within rheumatology. These include issues of equipment costs, training and certification and the relationship of rheumatologists and radiologists in advancing the field of MSUS. Rheumatologists must demonstrate the relevance of MSUS in their clinical practice through high-quality research. Emerging technologies such as power Doppler and 3D imaging will further improve imaging capabilities and the range of clinical applications of MSUS systems. This paper reviews how MSUS in rheumatology has evolved and the controversies and issues that rheumatologists must now address in developing MSUS as an indispensable, everyday clinical tool.

Clinical Competence↗