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Interventional musculoskeletal radiology.

Interventional procedures constitute a significant proportion of musculoskeletal radiology. Percutaneous needle biopsy is the ultimate diagnostic technique for the evaluation of musculoskeletal neoplasms and infections. The procedure is accurate, rapid, and safe. It is ideally suited for the diagnosis of metastatic disease and round cell neoplasms. Several needle procedures have been used for the diagnosis and treatment of low back pain. Diskography is primarily a diagnostic test used to determine the symptomatic disk level when multilevel disk disease is present and also to diagnose internal disk disruption. Nerve block with local anesthetic is also used to locate the symptomatic level in patients with multilevel abnormalities. Epidural steroid injection is a therapeutic procedure that commonly is used in patients with low back pain and has been shown to be most effective in patients with disk herniation. Facet joint injection with local anesthetic and steroid is performed to diagnose and treat the facet syndrome. Other needle procedures in the musculoskeletal system include sacroiliac joint aspiration and injection, prosthetic joint aspiration to evaluate potential infection, distention arthrography, and injections of the coccyx for coccydynia.

Adrenal Cortex Hormones↗

Current status of musculoskeletal interventional radiology.

This article details many of the latest developments in the field of musculoskeletal interventional radiology. Some of the topics included in this discussion are percutaneous biopsy of musculoskeletal lesions, automated percutaneous discectomy, facet joint arthrography, percutaneous vertebroplasty, and percutaneous drainage of abscesses.

Biopsy, Needle↗

Magnetic resonance--guided musculoskeletal interventional radiology.

As an imaging modality, magnetic resonance (MR) guidance has great potential to direct diagnostic and therapeutic procedures performed in the musculoskeletal region and influence patient management. MR-guided interventional procedures involving bone, soft tissue, intervertebral discs, and joints are safe and sufficiently effective for use in clinical practice. This article discusses and illustrates the procedural characteristics and techniques when performing MR-guided musculoskeletal interventions. Biopsy procedures are similar to other modalities for bone and soft tissue lesions. MR guidance is advantageous if the lesion is not visible by other modalities and for regions adjacent to hardware and implants, subselective targeting, intra-articular locations, and periarticular cyst aspiration. MR guidance has also been used for a host of spine injections and pain management procedures such as sacroiliac joint injections, discography, transforaminal epidural injection, selective nerve block, sympathetic block, celiac plexus block, and facet joint cryotherapy neurotomies. Future directions of clinical applications include tumor ablation and multimodality procedure suites. MR-guided musculoskeletal procedures will continue to be a growth area particularly for the diagnosis and treatment of bone and soft tissue neoplasia.

Humans↗

New Trends in Musculoskeletal Interventional Radiology: Percutaneous, MR_Guided Skeletal Biopsy.

Several different types of magnetic resonance (MR) scanners that allow access to the patient during image acquisition and thus permit MR-guided biopsies have been introduced. A variety of MR-compatible biopsy needles and a prototype coaxial drill system, powered either by hand or an optional motor, are presently available for sampling skeletal lesions. In a small study population of 28 patients in our hospital who required a biopsy of a skeletal lesion, all but five biopsy procedures could be completed within the MR unit. In one patient who required a transpedicular approach to a lumbar vertebra, we decided to switch to computed tomography (CT) guidance. Four patients needed general anesthesia, which is currently not available in our interventional MR suite. Those procedures were also performed under CT guidance. In 18 of the 23 MR-guided cases, the samples were sufficient and the histopathologic diagnoses were confirmed by surgery or the clinical course. Three biopsies contained an adequate volume in the sample, but the contents were either unrepresentative of the final pathology or distorted beyond recognition by the biopsy drill. Two others revealed insufficient material. No procedural complications occurred. Percutaneous biopsy of skeletal lesions performed under MR guidance seems to be a safe procedure and reasonably accurate given the fact that it is still in an early stage of development. MR imaging may be used as an alternative to CT, but its role vis-vis CT has yet to be ascertained.

Journal Article↗

Interventional radiology and the musculoskeletal system.

Imaging-guided interventional procedures are becoming increasingly important in clinical rheumatology, since arthrocentesis of peripheral joints and the spine, as well as soft tissue injections, have a high rate of para-articular localisation when performed as blind techniques. Ultrasound-guided needle placement is the method of choice for interventional procedures on peripheral joints and for soft tissue injections. Fluoroscopy and computed tomography (CT) are not recommended for these indications due to the application of ionising radiation and the high procedural effort. By contrast, CT and magnetic resonance imaging are preferred for a variety of percutaneous procedures on the spine and sacroiliac joints. The increasing use of these methods for interventional purposes should improve both technical and procedural quality, thus ensuring cost-effectiveness and patient safety.

Humans↗

Interventional radiology with laser in bone and joint.

Laser energy is able to ablate, coagulate, and vaporize tissues. Its transmissibility in thin optical fibers makes it an ideal tool for use in percutaneous procedures. This article describes two applications in interventional musculoskeletal radiology. In percutaneous laser disc decompression the laser source is used to vaporize a small portion of the nucleus pulposus. In interstitial laser photocoagulation of osteoid osteoma the laser energy is used to coagulate and destroy the tumor by direct heating.

Adolescent↗

Interventional radiology techniques in musculoskeletal disease.

It is likely that, over the next few years, the rapid technological advancements in ultrafast magnetic resonance imaging and ultrasound resolution improvements, coupled with a drive towards minimally invasive surgery, will further enlarge the scope of imaging guided interventional procedures. Such innovations should increase diagnostic accuracy for optimized treatment regimes as well as probably replace an increasing number of conventional 'open' operative procedures.

Humans↗

Where is imaging going in rheumatology?

Four new approaches to imaging are now becoming available. First is filmless radiology, with flat detectors that 'permit access' to PACS, the picture archiving communication system, and teleteaching. Second is ultrasonography (US), involving three-dimensional volume, harmonic Doppler energy and digital technology techniques, with contrast agents and biopsy needles. Next is computer tomography (CT), using volume acquisition multislices, spiral reconstruction and solid detectors, as well as multidetectors. Finally comes magnetic resonance imaging (MRI). A low magnetic field with an open MRI scan permits interventional radiology in musculoskeletal disease. High magnetic fields are mainly used for clinical research and permit rapid examination, in approximately 10 minutes. In interventional radiology, many procedures can be performed with the guidance of digital radiography, US or MRI. Two areas of localization have to be considered: the spine and the peripheral joints, particularly the shoulder, wrist and foot. Guidelines contribute to good medical practice, but there are other considerations, such as machine accessibility, the nature of the treatment, the personality of the patient and the role of the hospital. Overinvestigation has to be avoided for four reasons: an increase in patient anxiety, the cost of health-care management, the risk of irradiation and sometimes the lack of diagnostic value of these procedures. In rheumatoid arthritis, MRI can detect lesions at an earlier stage of their development and identify subtle lesions and synovitis. Imaging (using x-rays, MRI and US) is important in the assessment of the effectiveness of slow-acting drugs in rheumatoid arthritis, especially since joint damage can progress in spite of a clinical improvement in joint inflammation. In the future, teletransmission, by the Internet or intranet and using PACS, will change our approach to the diagnosis of musculoskeletal disease. Future developments therefore include PACS, filmless radiology, the Internet and intranet, harmonic US, multidetector CT scanning and open MRI on the technical side, as well as the study of cartilage and international radiology on the clinical side.

Arthritis, Rheumatoid↗

Gelified ethanol for percutaneous sclerotherapy of bone lesions: a systematic review of clinical applications and outcomes.

PURPOSE: To systematically review the available evidence on the feasibility, safety, and clinical effectiveness of percutaneous sclerotherapy using radiopaque gelified ethanol (RGE, Discogel®) for bone lesions. METHODS: A systematic search of MEDLINE, Embase, Web of Science, and Cochrane CENTRAL was performed. Primary studies reporting clinical, technical, and safety outcomes following RGE sclerotherapy for bone lesions were included. Data on patient characteristics, lesion type, procedural details, and outcomes were extracted and synthesized descriptively. RESULTS: Six retrospective studies involving 55 patients (mean age 22.2 ± 20.4 years; range 3-65; 26 females) with 56 lesions and 119 procedures were included (mean 2.16 procedures per patient). Aneurysmal bone cysts (80%) and aggressive vertebral hemangiomas (18%) were the main indications. Technical success was reported in 100% of procedures. Pain outcomes were available for 28 patients, with complete resolution in 64.3% (18/28), partial reduction in 32.1% (9/28), and persistence in 3.6% (1/28). Radiological follow-up (50 lesions) demonstrated complete response in 96% and partial response in 4%. No major adverse events were reported according to CIRSE (≥ 4) or CTCAE (≥ 4) criteria. One SIR grade 3 vertebral fracture occurred without confirmed causal association to RGE. Subsequent surgery was required in 3.6% of lesions. CONCLUSION: Although limited to small retrospective series, current evidence suggests that RGE sclerotherapy is a safe and effective minimally invasive option for selected benign bone lesions. Prospective comparative studies with longer follow-up are warranted.

Humans↗

Treatment of musculoskeletal vascular anomalies.

The treatment of musculoskeletal vascular anomalies can be accomplished by means of challenging image-guided interventional techniques. Most patients benefit clinically from these procedures. Careful planning, appropriate training, and adequate patient care during and after the procedure are important to achieve optimal results and to minimize procedure-related risks.

Angiography↗

A perspective on radiology residency curriculum guidelines: results of the 1995 survey of program directors.

RATIONALE AND OBJECTIVES: The development of curriculum guidelines for radiology residency has been found to be favored by 80% of program directors (PDs) nationwide. I surveyed PDs to develop a consensus of opinion concerning minimum training requirements in the subspecialty rotations. METHODS: A survey developed by members of the Ad Hoc Curriculum Committee of the Association of Program Directors in Radiology was mailed to all U.S. PDs. RESULTS: One hundred forty-one (82%) completed responses were received. There was agreement among the PDs about the minimum length of training needed in the various subspecialties. Seventy-four percent of the PDs supported the concept of developing educational objectives and goals in each subspecialty and of specifying procedures in which residents should be trained. Only a minority of PDs thought that the training guidelines should specify minimum numbers of procedures. CONCLUSION: The consensus of PDs is that the radiology residency curriculum should include a minimum of 3 months in each of the following categories: chest radiology, gastrointestinal radiology, musculoskeletal radiology, pediatric radiology, cardiovascular and interventional radiology, sonography, and body computed tomography (CT) scanning. In neuroradiology, inclusive of neuroangiography, neuro CT scanning, and neuro magnetic resonance (MR) imaging, a resident should spend 4 months. At least 2 months should be devoted to each of the following: uroradiology, mammography, body MR imaging, and emergency radiology. A majority of PDs also favored developing educational objectives for each of the subspecialty rotations.

Curriculum↗

Speech processing in radiology.

The goal of this study was to evaluate the recognition rate, learning potential and amount of time needed to complete a report with the Philips speech recognition system SP 6000 (Philips, Best, The Netherlands). Four radiologists dictated reports of interventional radiology, MRI examinations of the musculoskeletal system and CT examinations of the thorax and abdomen with the Philips system using the German language. The recognition rate of each report and improvement rate after each learning phase of the Philips system was assessed. The time needed to complete a report using the Philips system was then compared with the time needed to complete a report using the tape-based system via a time analysis. The average recognition rate for the four radiologists using the Philips system was 79.6 %, which improved to 92.5 % after the third adaptation. Initially, the average time demand to dictate and correct one report was approximately 16.8 min, but this time decreased to 8.1 min after the third adaptation. In contrast, only 3. 6 min were needed to dictate and correct one report using the tape-based system. However, with the speech recognition system, dictation, correction and transcription of the report can be completed within 15 min, whereas with the tape-based system, it takes nearly 1 day. With the Philips system, speech recognition can reach as high as 95 % since each adaptation of the system improves the recognition rate by approximately 5 %. While the Philips system is associated with longer dictation times than the tape-based system, turn-around time for a complete report is substantially shorter with the Philips system than the tape-based system.

Computer Communication Networks↗

Role of radiology in occupational medicine.

This review discusses the contribution of radiology to occupational medicine as well as work-related problems in radiology departments. Research issues are emphasized. Radiology has been used especially when diagnosing occupational respiratory and locomotive system problems and solvent-induced encephalo- and hepatopathy. The aim of research in these areas is usually to characterize occupational diseases and to identify physico-chemical hazards in the work place by comparing between groups of workers and non-exposed controls. Radiological imaging allows an objective characterization of the disease, and it may clarify the pathogenesis of the process and provide a useful epidemiological tool. Advanced statistical methods are often needed to adjust analyses for confounding variables. As the diagnostic requirements are increasing, more sensitive and sophisticated radiological methods, such as high-resolution computed tomography, magnetic resonance imaging and magnetic resonance spectroscopy, may be required for the early recognition of occupational health risks. This necessitates good cooperation between occupational health units and well-equipped imaging departments. Considering occupational problems in radiology departments, the increasing use of digital radiology requires ergonomic measures to control and prevent locomotive problems caused by work with computers. Radiation protection measures are still worth concern, especially in interventional radiology.

Cumulative Trauma Disorders↗

[Surgical therapy concept in primary hyperparathyroidism].

INTRODUCTION: Primary hyperparathyroidism is a relatively rare disease caused in 80-85% of cases by solitary adenoma of the parathyroid glands. The laboratory findings are hypersecretion of PTH and hypercalcaemia. We distinguish between asymptomatic and symptomatic primary hyperparathyroidism. 25 patients of our clinic who underwent surgery in 1996 and 1997 are presented to illustrate our surgical concept of therapy. METHODS: 7 patients were asymptomatic and 18 symptomatic with regard to primary hyperparathyroidism. Preoperative localisation was facilitated by ultrasonography of the neck, which was used in all cases. Bilateral exploration of the neck under general anaesthesia similarly to thyroidectomy was the gold standard. Monitoring the inferior laryngeal nerve helped to protect it. In 6 cases intraoperative parathyroid hormone monitoring (rapid PTH assay) was applied. RESULTS: More than a third of the symptomatic group of patients had neurological or psychiatric diseases, followed by symptoms of the musculoskeletal and urological systems. Possible reasons for surgical intervention were persistent hypercalcaemia, age over 50, radiological findings of kidney stones or decreased kidney function. In 17 patients the preoperative ultrasonographic localisation was consistent with the intraoperative clinical findings. The sensitivity of this method was 68%. Intraoperative pathology showed 17 patients with a solitary adenoma, 4 ectopic, 2 cases had double adenoma, and 2 others hyperplasia with enlargement of all glands. After resection of the pathological parathyroid glands there was a decrease of parathyroid hormone in intraoperative hormone monitoring of approximately 60%. The preoperative hypercalcaemia (mean 2.99 mmol/l) usually normalised 4 hours postoperatively. There was no severe intraoperative bleeding and the inferior laryngeal nerve was preserved in all cases. All patients were monitored at 3-month intervals for parathyroid hormone and serum calcium during the first year after operation. One patient had persistently elevated parathyroid hormone without clinical findings. DISCUSSION: Parathyroidectomy is an efficient and safe operation with excellent normalisation of serum calcium and parathyroid hormone and a high rate of patient satisfaction. In this study assessment of ultrasonography was the preferred method of locating enlarged parathyroid glands before operation. However, this method is not based on unilateral exploration of the glands. Therefore, we prefer to locate all four glands, an approach based on the literature [1, 2]. Intraoperative monitoring of parathyroid hormone facilitates assessment of the operative result [3]. Normalisation of calcium in serum and the effectiveness and safety of the surgical method are confirmed in other publications [4-8]. In 24 of our patients normocalcaemia resulted within 12 hours after operation and in one patient within 4 days. One year after operation and endocrinological checkup all 25 patients were asymptomatic and normocalcaemic, while one patient had persistently high parathyroid hormone of unknown origin.

Adenoma↗

Radiological review of accident and emergency radiographs: a 1-year audit.

AIM: To assess the impact and cost effectiveness of a system of radiological review of accident and emergency (A&E) plain films. MATERIALS AND METHODS: Review documentation was studied retrospectively over a 1-year period. Six hundred and eighty-four actual or suspected errors in the initial radiological interpretation by A&E staff were highlighted by radiologists in training. These selected 'red reports' were then further reviewed by a musculoskeletal radiologist and a more senior member of the A&E team. RESULTS: Three hundred and fifty-one missed or strongly suspected fractures were detected, with ankle, finger and elbow lesions predominating. Other errors included 11 missed chest radiograph abnormalities and 24 A&E false-positives. Radiologists in training tended to over-report abnormalities with an 18% false-positive rate when compared to the subsequent musculoskeletal radiology opinion. Following review, further action was taken by A&E staff in 286 (42.6%) of cases. No operative intervention was required in those patients with a delayed or missed A&E diagnosis. Consideration is given to the cost of providing this form of review and the impact of medico-legal factors. CONCLUSION: Compared with the large numbers of patients seen and radiographed in a busy A&E department, the number of radiological errors was small. There were even fewer changes in management. Despite this, concern over litigation, clinical governance and future work patterns in A&E make this form of review a useful means of risk reduction in a teaching hospital.Williams, S. M. (2000). Clinical Radiology55, 861-865

Cost-Benefit Analysis↗