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A double blind study of pimozide versus chlordiazepoxide in anxiety neuroses.

Eighteen patients diagnosed as anxiety states were treated under double blind conditions for a four week trial period with pimozide and chlordiazepoxide after randomisation. No significant differences could be demonstrated between chlordiazepoxide and pimozide as far as therapeutic efficacy or toxicity were concerned. Pimozide administered in a single daily dose was as effective as chlordiazepoxide administered in divided daily doses for the relief of anxiety symptoms.

Adolescent↗
PubMed1986

Anxiety neuroses and DSM-III.

The relationship between ICD-9 anxiety states, phobic states, obsessive-compulsive disorder and DSM-III anxiety disorders is discussed. Data are presented which show that one third of ICD-9 anxiety states are diagnosed as affective disorders by DSM-III. Research concerning cases with a concurrent affective and anxiety disorder is discussed. It is finally concluded that while DSM-III has unsolved hierarchial problems, the identification of the two disorders, panic disorder and generalized anxiety disorder, seems advantageous and the inclusion of obsessive compulsive disorder, among the anxiety disorders, reasonable.

Agoraphobia↗