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At least 19 recordsLinked to original sources
PubMed1976

Detection of plasmacytoma of the nasal cavity by immunoelectrophoresis of nasal washing fluid.

A patient with a solitary IgG-lambda plasmacytoma of the nasal cavity is described. Immunoelectrophoresis of the nasal washing fluid showed the presence of the same paraprotein. After radiotherapy the tumour and the paraprotein disappeared. Recurrence of the tumour after 6 months was again associated with the presence of the paraprotein in the nasal washing fluid. Immunoelectrophoresis of nasal washings may offer an easy method in detection and follow-up of localized plasmacytomas of the upper respiratory tract.

Aged↗
PubMedDate not supplied

Microbiology of the canine nasal cavities.

The microbiota of both nasal cavities were investigated in 37 dogs by both aerobic and anaerobic techniques. The predominant microorganisms were composed of enterococci and staphylococci. A surprisingly high incidence (46%) of Gram-negative rods was noted from the inferior portion of the nose. Microorganisms from the superior region of the nose, as obtained with a surgical approach, differed both qualitatively and quantitatively from the respective transnasal cultures. Thus, it appears that different bacterial populations are present within various anatomic regions of the nose and a routine transnasal culture cannot accurately reflect the microbiology of the entire nasal cavity.

Animals↗
PubMed1977

[Development of the nasal cavity and formation of the nostrils in human embryogenesis].

The development of nasal cavity was traced in human embryos. The identity in the primitive formation of the mouth cavity and that of the nasal cavity is stated. During embryogenesis, the primitive nasal cavities are demonstrated to change their position concerning the mouth cavity. Epithelial "cluster" formation in the area of the nostrils is examined: it appears in embryos of 16-19 mm long, is mostly prominent in embryos of 50-55 mm long, is absent in fetuses of 5.5 months old. By comparing the terms and dynamics in the development of epithelial adhesion in the larynx an the nostrils, the importance of these temporal structures for protecting the respiratory tract of the embryo from amniotic fluid is demonstrated.

Female↗
PubMed1977

Non-epithelial tumors of the nasal cavity, paranasal sinuses and nasopharynx: a clinicopathologyic study. VIII. Adipose tissue tumors (lipoma and liposarcoma).

In a study of 256 non-epithelial neoplasms involving the nasal cavity, paranasal sinuses and nasopharynx, only two lesions were classified as adipose tissue tumors (one lipoma and one liposarcoma). The lipoma was found incidentally when tissue removed from the maxillary sinus was studied histologically, the patient having been treated with a Caldwell-Luc procedure for maxillary sinusitis. The liposarcoma produced a large mass involving the nasal cavity, maxillary sinus, ethmoid area, hard palate and maxillary, temporal and sphenoid bones. The tumor extended into the cranial cavity and eventually led to the patient's death. The problems involved in histologically differentiating liposarcomas from other lesions are discussed. Even though adipose tissue tumors are among the most common soft tissue neoplasms, these lesions rarely occur in the nasal cavity, paranasal sinuses and nasopharynx.

Adult↗
PubMed1978

Surgical approach to tumors of the nasal cavity.

In the past there has been a general reluctance among rhinologists to remove the entire lateral nasal wall for fear of causing drastic disturbances of nasal physiology. It has been our observation that the physiological disturbances are fairly minimal if the patient, following surgery, uses nasal saline irrigations daily. Sometimes a nasal siphon or water pik is required to prevent crusting. It has also been noted that when the septum is removed, a chronic antritis on the contralateral side will usually occur. It has been our practice to do an antrostomy on the uninvolved side when the septum has been removed for any reason. Ophthalmologists have shown some reticence to having the entire bony support of the medial wall of the orbit and half the floor removed. This does necessitate transecting the lacrimal duct at its neck. We have, however, seen no trouble with epiphora following this provided the sac was allowed to drain in to the open nasal cavity. The trochlea is by necessity deprived of its support; however, the periostium seems to provide adequate support here and we have noticed no troublesome permanent problems with function of this muscle. The periorbita, which has been robbed of its osseous support, quickly epithelializes with nasal mucosa and becomes a part of the nasal cavity. Requirements for intranasal douching with saline have varied; however, we have had no problems with bothersome crusting following b.i.d. nasal irrigations. In cases where a small portion of the inferior turbinate could be preserved, there was always extreme hypertrophy of this remnant which usually brings the nasal physiology back to a nearly normal state which seldom requires any special care whatever. This paper presents primarily a method of approaching tumors of the sinonasal area, especially when there is difficulty in determining whether the lesion arises from the septum or lateral wall of the nose.

Aged↗
PubMed1977

Malignant teratoma of the nasal cavity.

A case of malignant teratoma of the nasal cavity in an adult is presented. Histologically, the tumor consisted of mesenchymal malignant structures in addition to entodermal and ectodermal malignant elements. Whereas surgical treatment of the primary tumor has been generally considered preferred, this patient was given a full course of radiation therapy alone to the primary lesion. There is no clinical evidence of tumor 5 years following diagnosis. Three years following treatment of the primary tumor, neck lymph node metastasis appeared contralaterally. Management of this problem was with radical neck dissection followed by postoperative radiotherapy. Function of the eyes, nose, and paranasal sinuses remains normal. A review of the literature suggests that radiotherapy is of little value in the management of malignant teratomas. This case demonstrates an opposite point of view.

Ethmoid Sinus↗
PubMedDate not supplied

Chondrosarcoma of the nasal cavity, paranasal sinuses, and nasopharynx.

Thirteen patients, six men and seven women, were seen at the Mayo Clinic with chondrosarcomas of the nasal cavity, paranasal sinuses, or nasopharynx in a 25-year period. Nasal obstruction, discharge, and bleeding were the major symptoms and a nasal mass was the most common sign. The typical chondrosarcoma is low in grade but malignant and it arises in the nasal cavity as a large, pale, glistening mass. Local excision was employed initially in seven patients and five had local recurrence. Definitive block excision cured four of six patients and the two others had a protracted clinical course and ultimately died of the disease. Long-term follow-up shows that chondrosarcomas are insidious, locally progressive tumors. Radiotherapy, used for palliation after recurrence, failed to produce any cures. Lateral rhinotomy and block excision are advocated as the primary treatment.

Adolescent↗
PubMed1979

Late effects on the eye of conformation radiotherapy for carcinoma of the paranasal sinuses and nasal cavity.

Sixty patients with carcinoma of the paranasal sinuses and nasal cavity were treated with conformation radiotherapy technique (an improved moving-field technique). Only 28 were suitable for long-term follow-up with regard to eye complications. All patients receiving more than 5,800 rads in 6 weeks (1,700 reu in cumulative-radiation-effect dose) had strong panophthalmia with corneal ulceration within 2 years of radiotherapy. Of 21 eyes receiving 800--1,700 reu (2,800--5,400 rads in 6 weeks), 18 experienced visual disturbance from radiation cataracts and 3 equivocal changes at postirradiation intervals of 5 years. No patient receiving less than 800 reu (2,800 rads in 6 weeks) showed such complications.

Cataract↗
PubMed1979

[Malignant tumors of the nasal cavity and paranasal sinuses (author's transl)].

Therapeutic results from 134 cases with malignant tumors of the nasal cavity and paranasal sinuses are reported. Retrospective classification based on clinical and roentgenological findings was possible in 121 cases. 49 patients underwent primary radiation treatment by 60Co-teletherapy, 46 were exposed to postoperative irradiation. The mean 2-year survival rate considering all stages and all kinds of malignant tumors amounts to 52%, the 5-year survival rate to ca. 32%. The 5-year survival rate obtained by means of curative tumor doses was 59%. Recurrences of the tumor appeared in 58 cases (43%), most of them in the course of a year. The therapeutic control of local tumor disease and the possibilities of an early detection of recurrences, improved with the help of new diagnostic methods, must therefore be regarded as the essential problems. No generally approved clinical classification of tumors of the nasal cavity and paranasal sinuses is available as yet, and the comparison of therapeutic results from different authors thus is difficult.

Adolescent↗
PubMed1979

Cancer of the nasal cavity and ethmoid/sphenoid sinuses.

During the period from October 1964 to September 1975, 32 patients were treated at the University of Florida for a variety of malignant tumors of the nasal cavity and ethmoid/sphenoid sinuses. All were treated with radical irradiation, 6091 to 7972 rad, in 6 to 9 weeks, cobalt-60. Pretreatment work-up revealed evidence of orbital invasion in 7 patients and involvement of the cranial contents, base of skull, or nasopharynx in an additional 15 patients. Local control was achieved in 95% of nasal cavity cases and 71% of ethmoid/sphenoid sinus cases at 2 years or more. The 5-year actuarial survival rate was 59%, and 5-year survival without evidence of disease was 50% (13/26). Patterns of extension in advanced lesions are clues to potential undetected extension in early cases which must be included in the treatment volume. Eye complications were minimal when it was possible to avoid treatment of the entire eye, but developed in all cases requiring treatment of the entire orbit. Acute and chronic complications involving the eye, ear, central nervous system, sinuses, and nose were reviewed and correlated with initial tumor extent, dose, and radiation treatment technique.

Blindness↗
PubMed1979

Lateralisation of tumours of the nasal cavity and paranasal sinuses and its relationship to aetiology.

Lateralisation was studied in 601 cases of carcinoma of the nasal cavity and paranasal sinuses. Squamous and anaplastic carcinomata and adenocarcinoma had a pronounced left-sided predominance in the ethmoid and to a much lesser extent in the nose. The results of a study of 298 cases of septal defection are invoked in support of the hypothesis that squamous and anaplastic carcinomata, as well as adenocarcinoma, are caused by exogenous factors.

Adenocarcinoma↗
PubMed1978

Primary neoplasms of the nasal cavity, paranasal sinuses and nasopharynx in the dog. A report of 16 cases from the files of the AFIP.

Sixteen cases of primary neoplasms of the nasal cavity, paranasal sinuses and nasopharynx in the dog were reviewed from the files of the Armed Forces Institute of Pathology (AFIP). The mean age of affected dogs was 9.5 years. The presenting clinical signs were epistaxis, nasal discharge or facial swelling. Eleven of the affected dogs were purebred. Three of these were Collies and two German Shepherds. The nasal cavity was involved most often. All neoplasms were malignant (11 carcinomas and five sarcomas), and there was invasion of the adjacent bony structures in most dogs. Tumors were classified according to prominent cell type and degree of differentiation into respiratory epithelial carcinoma (four), adenocarcinoma (one), squamous cell carcinoma (one), mucoepidermoid carcinoma (two), undifferentiated carcinoma (three), chondrosarcoma (three) and undifferentiated sarcoma (two).

Adenocarcinoma↗
PubMed1979

CT anatomy of the nasopharynx, nasal cavity, paranasal sinuses, and infratemporal fossa.

Analysis of anatomical features of the nasopharynx, nasal cavity, paranasal sinuses, and infratemporal fossa was carried out by retrospective review fo 50 CT scans. Conventional and axial anatomy are discussed, and normal size limits of selected structures are proposed on the basis of a series of measurements. Examples of early and advanced disease are shown.

Humans↗
PubMedDate not supplied

[Pituitary neoplasms extending into the nasal cavity and their needle biopsy cytodiagnosis].

In 5.5% of 126 patients treated for hypophyseal tumors at the Burdenko Institute of Neurosurgery, AMS USSR for 12 months, spread of the new growth to the nasal cavity was revealed. The tumor was usually located in the posterosuperior parts of the nose and was discovered on anterior rhinoscopy only after the nasal mucosa had been carefully anemized, particularly with the use of a nasal dilator with a lamp on its end specially designed by us. Spread of a hypophyseal tumor to the nasal cavity was encountered when the tumor was very large and grew regularly in all directions or when it was marked by selective infrasellarg growth in the direction of the sphenoidal sinus. Cytologic examination of the punctate made it possible to determine the presence of the hypophyseal tumor and its character (benign, malignant) and differentiate it from other new growths and from c.s.p. cysts.

Adenocarcinoma↗
PubMedDate not supplied

Hemangiopericytoma of the nasal cavity.

Only 12 cases of nasal hemangiopericytoma have been reported in the literature. Ten additional cases are presented herein. Surgical excision is the recommended treatment; cryosurgery was used in one of our patients. Four of the tem patients had recurrences, one of which proved to be malignant (with distant metastases to the lung) and was ultimately fatal.

Adult↗
PubMed1979

[Headache caused by deformation of the nasal septum and by deviation disorders of the nasal cavity].

In case of uncertain pain of the frontal, nasal and maxillary area one must search for disturbed ventilation of the nose or its communications. Particularly so, if no radiological evidence is found. Anatomical changes may cause a primary irriation of the mucosa, when ventilation is distirubed or when there is direct contact between septum and conchal mucosa. As a reaction to such primary disturbance, ventilation to the maxillary sinuses may be inhibited, thus causing a secondary irriation. Thus a recidivating acute maxillary pain may occur without a real sinusitis, because of a hypoxia of the sinus. Rhinoscopy resp. nasal endoscopy will clear up anatomical primary causes. Conchal contact should be eliminated by lateroposition or by pinching. The septum deviation should be corrected if by nasal drops or spray the pains may be eliminated. Sinus obstruction may be diagnosed by rhinomanometry and sinuscopy and may be simultaneously treated by a small drainage tube.

Headache↗