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At least 19 recordsLinked to original sources
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[Treatment of patients with malignant neoplasms of the nose and paranasal sinuses].

The author analyzes and discusses characteristic features of the results of combined treatment in 260 patients with malignant tumours of the superior maxilla, nose and accessory sinuses. The majority of patients were from 40 to 60 years old (81.5%). These were 158 men and 102 women. Epithelial tumours were diagnosed in 91.5%, sarcomas in 8.5% cases. The flattened-cell form of cancer with or without keratosis was diagnosed in 82.7%; other forms of cancer-in 17.3% cases. Sarcoma in women was diagnosed 3.5 times as often as in men. Tumours of the I stage were found in 12, of the II stage in 34. of the III stage in 146, of the IV stage in 73 patients. All patients were subjected to combined treatment-telegammatherapy and resection of the tumour with an electroknife. Patients with cancer of the I stage were first operated on with the electroknife and then subjected to radiotherapy with a focal dose of 3000-4000 rad. The 34 patients with cancer of the II stage underwent preoperative radiotherapy with a focal dose of 4500 to 5000 rad, then surgical intervention followed in 2-5 weeks. Preoperative radiotherapy was practiced in the 146 patients with cancer of the III stage, the total dose per focus being 5000-6000 rad, surgical intervention followed in 3-5 weeks. The 73 patients with cancer of the IV stage were operated on after radiotherapy with a focal dose of 6500-700 rad. Early and remote results of combined treatment in 260 patients were favourable. The length of life was up to 3 years in 119 (45.77%), up to 5 years in 74 (28.46%), up to 10 years in 48 (18.5%), over 10 years in 22 (8.5%) patients.

Adolescent↗
PubMed1975

Cytology of bronchial washings: a study of patients with malignant neoplasms of the head and neck.

Among 18 patients with locally advanced malignant neoplasms of the head and neck region, bronchial washings failed to reveal tumor cells despite the demonstration of exfoliated tumor cells in washings from the region of the primary tumor in 13 (72 percent) of the patients. Among 17 patients with bronchogenic carcinomas, however, tumor cells were isolated from the bronchial washings in 14 (82 percent). These results indicate that, in patients with malignant neoplasms of the head and neck, tumor cells found in bonchial washings probably are not from the primary head and neck neoplasms. Thus, cytologic examination of bronchial washings may be validly employed in the differential diagnosis of the pulmonary tumors in patients with malignant neoplasms of the head and neck region.

Bronchi↗
PubMed1977

High-energy photon and electron beam.

The optimum radiation treatment plan for any given clinical situation can be achieved by combining various irradiation modalities and beam energies. The availability of equipment that provides photon and electron beams of energies from 4 MeV to 25 MeV permits optimal dose distribution throughout the treatment volume. Since no difference in the biological effectiveness of electrons compared with megavoltage photons has been demonstrated in laboratory studies, there is no hesitation in combining electrons with photons. The selection of the various energies, the combination of electrons with photons, and the ratio of the given doses of each beam depend on the location of the tumor and the maximum depth to be treated. With the use of one beam alone, a combination of 25 MeV and 4 to 6 MeV photon beams, or a combination of photons and electrons, the most effective treatment plan with the available beams can be designed for any clinical situation.

Adult↗
PubMed1978

Nonepithelial tumors of the nasal cavity, paranasal sinuses and nasopharynx. A clinicopathologic study. IX. Plasmacytomas.

Plasmacytomas occasionally may arise in extraosseous sites, of which the upper respiratory tract is the most common. In our series of 256 nonepithelial tumors involving the nasal cavity, paranasal sinuses and nasopharynx, 10 (4%) were apparently primary extramedullary plasmacytomas. Of our patients with adequate follow-up information, four died of disseminated disease 2, 4, 5 and 6 years after the initial diagnosis. One was alive 6 years after diagnosis with locally persistent tumor. Another was living without recurrence 12 years later. Based on our findings and on the cases reported in the literature, extramedullary plasmacytomas arising in the head and neck area may evolve into one of several different patterns. 1) Some patients have localized disease which is apparently controlled (by surgery, radiotherapy or both) and which never recurs locally or becomes disseminated. 2) In some cases, the tumor recurs locally and is controlled by further therapy. 3) Other patients have a locally persistent and aggressive lesion which cannot be eradicated and which eventually leads to the patient's death by uncontrolled local growth. 4) Still other patients eventually develop evidence of plasma cell neoplasms elsewhere in the body and/or multiple myeloma.

Adult↗
PubMed1979

Nonepithelial tumors of the nasal cavity, paranasal sinuses and nasopharynx: a clinicopathologic study. X. Malignant lymphomas.

In our series of 256 nonepithelial tumors involving the nasal cavity, paranasal sinuses and nasopharynx, 21 were apparently primary malignant lymphomas, including 17 ordinary lymphomas and 4 cases of "midline malignant reticulosis." Of the 15 patients who had ordinary lymphomas and had adequate follow-up, 8 died of lymphoma, 4 were living with disseminated disease, 1 died of other causes with persistent lymphoma and only 2 (13%) had no evidence of recurrence at 8 and 9 years after diagnosis. The tumor was controlled in its primary site by radiotherapy in 13 of 14 patients; however, all but 2 of these patients eventually developed disseminated disease. Of the 3 patients who had midline malignant reticulosis (MMR) and had adequate follow-up, all died of disease. MMR represents an unusual variant of malignant lymphoma and often produces the clinical picture of lethal midline granuloma.

Adult↗
PubMed1975

Head and neck cancer manpower study.

1. Approximately 40,000 cases of cancer of the head and neck (excluding skin) are diagnosed each year. 2. Approximately 20,000 of these cases and 30,000 cases of skin cancer are treated by 366 head and neck cancer surgeons. 3. Ninety per cent of the cases are treated by 63 per cent of the surgeons. 4. Fifty-eight per cent of the surgeons care for between 50 and 300 cases per year. 5. While 2,759 new board-certified surgeons of all specialties are recruited annually to maintain a work force of 46,000 board-certified surgeons (3), apparently 730 potential head and neck cancer surgeons are being prepared to maintain a work force of approximately 450 head and neck cancer surgeons. 6. These findings indicate the need for in-depth study of the manpower needs in head and neck cancer surgery by all who are responsible for the training of surgeons in this field.

General Surgery↗
PubMed1976

Clinical staging of cancer of the head and neck: a new "new" system.

A revised clinical staging system for cancers arising in head and neck sites has been prepared. It utilizes a uniform N classification for cervical node metastases. The T classifications describing the extent of the primary tumor are generally similar but differ in specific details for each site. Although the present system makes use of past field trials and more recent clinical studies, it cannot be considered final. Clinicians managing cancer in head and neck sites are encouraged to test the system with their own patient data to elicit further areas for improvement.

Head and Neck Neoplasms↗
PubMed1977

Computed tomography of the paranasal sinuses and their adjacent structures.

Forty-five computed tomographic examinations were performed on 34 patients with diseases of the paranasal sinuses and their adjacent structures. Coronal sections were obtained in addition to transverse axial tomographic sections. Evaluation was made whether CT could provide more informations compared with plain roentgenography and whether there were additional informations on coronal sections. CT showed soft tissue abnormality and its extension to better advantage. Especially, involvement of the orbits, pterygoid fossa, nasopharynx, skull base and brain were shown well. Coronal sections were useful in evaluation of superior and inferior extension of the tumors such as involvement of the superior and inferior orbital walls and skull base as well as intracranial extension. Since CT has the ability to better define the total extent of the lesion, this technique should be added to the conventional roentgenologic techniques preferably with the use of coronal sections.

Bone Diseases↗
PubMed1977

Epithelial (inverted) papilloma: a correlated radiological--histological study.

The radiological and pathological features in 14 cases of epithelial papilloma are described. The typical radiological findings are a mass in the nares and sinus opacification, usually on the same side. Occasionally, extension of the mass into the nasopharynx is observed. Bone destruction may be present in epithelial papilloma, possibly due to pressure erosion. In the presence of carcinoma, bone destruction may be due to direct invasion.

Adult↗