SEARCH · PubMed Health
Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
Thrombocythemia is characterized by an increase in platelet numbers coupled with abnormal function. Three cases diagnosed after referral to an oral surgeon are presented. In each case the reason for referral concerned excessive dental hemorrhage. Thrombocythemia should be included in the differential diagnosis in cases of oral hemorrhage.
Follow-up examinations is mandatory with periodontal therapy in order to check the risk of recurrence. It comprises periodic check-ups, in which, at first, gingival inflammations and plaque causing such inflammation are evaluated together with the patient. Still in the same session, this is followed by conservative therapy. Apart from exact supra- and subgingival scaling, it is important to control and reinstruct the patient in personal oral hygiene. Interdental hygiene and the adjuncts selected according to the width of the inter-dental space play an important role in preventing inflammation. The time required for follow-up examinations in patients with periodontal disease calls for auxiliary personnel, especially the fully qualified dental hygienist.
Explore the source record for details and available documents.
Patients undergoing cancer chemotherapy often suffer from oral complications as a result of their disease and its treatment. The effects of the chemotherapy on the bone marrow and oral mucosa, coupled with the patient's immunosuppressed state and altered oral microbial flora, predispose these patients to oral mucositis, infection, and hemorrhage. The oral mucosa appears to mirror the effects of the chemotherapy on the bone marrow, as there appears to be a direct relationship between the changing peripheral blood counts and the status of the oral mucosa.
Explore the source record for details and available documents.
Gingival bleeding is not of decisive importance in diagnosticating periodontal diseases, since various endogenous causative factors and exogenous conditions may enhance its occurrence. In the absence of periodontal disease, gingival bleeding might be a symptom of a systemic disease. Because gingival bleeding is in most cases the first sign of an affection of the tooth-supporting structures that the patient observes, it should be, for all the difficulties its substantivation, be considered in history taking and for self-control.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A novel gingival tonometer is introduced with which definable pressures from 8.2-196.7 p/mm2 on the gum can be exerted. Bleeding from the gum can be produced by definable pressure, relating the inflammatory condition to the pressure insult and so achieving objective measurements. In 53 cases of periodontitis marginalis the results of treatment with a mouthwash containing chlorhexidine was tested. The gingivitis was so far improved by one week's treatment with the rinsing combination that in 1287 periodontitis cases the pressure had to be doubled before bleeding was produced.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Among 56 cases who presented to Kanto-Teishin Hospital complaining of bloody diarrhea or considerable hematochezia of acute onset, 8 cases (14.3%) were considered due to colitis associated with oral ampicillin therapy. The bloody diarrhea, often with abdominal cramps, began 2-7 days after starting the treatment. The dosage of ampicillin taken ranged from 2.0 to 4.5 g. Early total colonoscopy and biopsy revealed marked mucosal hemorrhage with minimal or no inflammatory changes mainly in the right colon. Rectum and sigmoid colon are completely normal except in one case. Symptoms rapidly resolved after the endoscopy. At follow-up colonoscopy, performed 4-12 days later, the mucosal changes had cleared completely. There was no evidence to support a hypersensitivity reaction of the colonic mucosa to ampicillin. We believe that right-sided hemorrhagic colitis is one of the common forms of colitis associated with ampicillin. Its differentiation from other kinds of acute colitis and the importance of early total colonoscopy are discussed.
Explore the source record for details and available documents.
An experimental clinical trial design is described in which the onset of gingival bleeding was used as an indicator of early gingivitis. Twenty-nine dental students participated in a double-blind crossover trial utilising chlorhexidine as a known plaque inhibitor. The onset of gingival bleeding was assessed in three ways, one of which yielded a statistically significant difference in favour of the active mouthrinse (P = 0.02). The method has a role in screening agents believed to be active against gingivitis.
Gingival bleeding is a difficult parameter to assess in experimental trials. The Confirmed Bleeding Day was recently developed as a measurement for this purpose. It was observed that considerable variations existed between the measurements made in a pilot study and an experimental trial, and these variations were subjected to a statistical analysis. The reasons for the variations are discussed, and recommendations made for the design of experimental trials involving gingival bleeding.