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Results for “PAKISTAN”

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At least 19 recordsLinked to original sources

PubMed2005

Prevalence and predictors of smoking in Pakistan: results of the National Health Survey of Pakistan.

OBJECTIVE: We analysed data collected during a nationwide cross-sectional household survey to estimate the prevalence of and identify factors associated with smoking in Pakistan. DESIGN: Population-based, cross-sectional survey [National Health Survey of Pakistan (NHSP) 1990-1994]. METHODS: A population-based survey was carried out in Pakistan during 1990-1994. A nationally representative sample of 18,135 individuals aged 6 months and older was surveyed. We restricted this analysis to individuals aged 15 years or older (n=9442). The main outcome measure was self-reported smoking. Smokers were defined as individuals who reported current smoking and having smoked at least 100 cigarettes or 'beddies' during their lifetime. RESULTS: Overall prevalence of smoking was 15.2% [95% confidence interval (CI), 14.5-15.9%]. It was 28.6% (27.3-29.9%) among men and 3.4% (2.9-3.9%) among women. The highest prevalence was reported in men aged 40-49 years (40.9%). The independent predictors of smoking identified in the multivariate logistic regression analysis included age, male gender, ethnicity and illiteracy. CONCLUSIONS: One out of every two to three middle-aged men in Pakistan smoke cigarettes. Our findings suggest that ethnically sensitive smoking control programmes that include measures for improving literacy rates are needed in Pakistan.

Adolescent↗

PubMed2007

Causes of blindness and visual impairment in Pakistan. The Pakistan national blindness and visual impairment survey.

OBJECTIVE: To determine the causes of blindness and visual impairment in adults (> or =30 years old) in Pakistan, and to explore socio-demographic variations in cause. METHODS: A multi-stage, stratified, cluster random sampling survey was used to select a nationally representative sample of adults. Each subject was interviewed, had their visual acuity measured and underwent autorefraction and fundus/optic disc examination. Those with a visual acuity of <6/12 in either eye underwent a more detailed ophthalmic examination. Causes of visual impairment were classified according to the accepted World Health Organization (WHO) methodology. An exploration of demographic variables was conducted using regression modeling. RESULTS: A sample of 16 507 adults (95.5% of those enumerated) was examined. Cataract was the most common cause of blindness (51.5%; defined as <3/60 in the better eye on presentation) followed by corneal opacity (11.8%), uncorrected aphakia (8.6%) and glaucoma (7.1%). Posterior capsular opacification accounted for 3.6% of blindness. Among the moderately visually impaired (<6/18 to > or =6/60), refractive error was the most common cause (43%), followed by cataract (42%). Refractive error as a cause of severe visual impairment/blindness was significantly higher in rural dwellers than in urban dwellers (odds ratio (OR) 3.5, 95% CI 1.1 to 11.7). Significant provincial differences were also identified. Overall we estimate that 85.5% of causes were avoidable and that 904 000 adults in Pakistan have cataract (<6/60) requiring surgical intervention. CONCLUSIONS: This comprehensive survey provides reliable estimates of the causes of blindness and visual impairment in Pakistan. Despite expanded surgical services, cataract still accounts for over half of the cases of blindness in Pakistan. One in eight blind adults has visual loss from sequelae of cataract surgery. Services for refractive errors need to be further expanded and integrated into eye care services, particularly those serving rural populations.

Adult↗

PubMed2006

Prevalence of blindness and visual impairment in Pakistan: the Pakistan National Blindness and Visual Impairment Survey.

PURPOSE: To determine the prevalence of blindness and visual impairment in adults aged 30 years and older in Pakistan and to assess socio-demographic risk factors. METHODS: Multistage, stratified (rural/urban), cluster random sampling, with probability proportional-to-size procedures, was used to select a nationally representative, cross-sectional sample of adults 30 years of age or older. Each subject was interviewed; had visual acuity measured (logMAR; logarithm of the minimum angle of resolution); and underwent autorefraction, biometry, and fundus-optic disc examination. Those with less than 6/12 acuity in either eye underwent a detailed ophthalmic examination, including corrected distance visual acuity measurement and dilated ophthalmoscopy. RESULTS: A nationally representative sample of 16,507 adults (95.5% of those enumerated) was examined. The age- and gender-standardized prevalence of blindness was 2.7% (95% confidence interval [CI], 2.4%-2.9%). It has been estimated that there are 1,140,000 (962,000-1,330,000) blind adults in Pakistan (2003 statistics). Blindness prevalence varied throughout the country, being highest in the provinces of Punjab and Baluchistan and lowest in the North West Frontier Province. Rural areas had a higher prevalence of blindness than did urban areas (3.8% vs. 2.5%, P < 0.001). Increasing age and being female were significantly associated with presenting visual acuity of <6/60 (odds ratio [OR], 2.5; 95% CI, 2.3-2.7 and 1.3; 95% CI, 1.1-1.5, respectively). Educational status was also associated with presenting visual acuity of <6/60. Subjects who had attended primary school were 60% (P < 0.001) less likely to have acuity of <6/60 than were subjects who had never been to school. CONCLUSIONS: This comprehensive survey provides reliable estimates of the prevalence of visual impairment and blindness in Pakistan. A significant excess of visual impairment was found among the elderly and the uneducated. After adjustment for age differences, women were found to have a significant excess of severe visual impairment and blindness. Regional variations in the prevalence of blindness were also identified.

Adult↗

PubMed1998

Antimicrobial resistance and clinical effectiveness of co-trimoxazole versus amoxycillin for pneumonia among children in Pakistan: randomised controlled trial. Pakistan Co-trimoxazole Study Group.

BACKGROUND: Co-trimoxazole is widely used in treatment of paediatric pneumonia in developing countries, but drug resistance may decrease its effectiveness. We studied the effectiveness of co-trimoxazole compared with that of amoxycillin in pneumonia therapy, and assessed the clinical impact of co-trimoxazole resistance. METHODS: We recruited 595 children, aged 2-59 months, with non-severe or severe pneumonia (WHO criteria) diagnosed in the outpatient wards of two urban Pakistan hospitals. Patients were randomly assigned on a 2:1 basis co-trimoxazole (n=398) or amoxycillin (n=197) in standard WHO doses and dosing schedules, and were monitored in study wards. The primary outcome was inpatient therapy failure (clinical criteria) or clinical evidence of pneumonia at outpatient follow-up examination. FINDINGS: There were 92 (23%) therapy failures in the co-trimoxazole group and 30 (15%) in the amoxycillin group (p=0.03)-26 (13%) versus 12 (12%) among children with non-severe pneumonia (p=0.856) and 66 (33%) versus 18 (18%) among those with severe pneumonia (p=0.009). For patients with severe pneumonia, age under 1 year (p=0.056) and positive chest radiographs (p=0.005) also predicted therapy failure. There was no significant association between antimicrobial minimum inhibitory concentration and outcome among bacteraemic children treated with co-trimoxazole. INTERPRETATION: Co-trimoxazole provided effective therapy in non-severe pneumonia. For severe, life-threatening pneumonia, however, co-trimoxazole is less likely than amoxycillin to be effective.

Amoxicillin↗

PubMed2006

Outcomes of cataract surgery in Pakistan: results from The Pakistan National Blindness and Visual Impairment Survey.

AIM: To evaluate the outcomes of cataract surgery in Pakistan. METHODS: Cross-sectional, nationally representative sample of 16 507 adults (aged >or=30 years). Each underwent interview, logarithm of the minimum angle of resolution visual acuity (VA), autorefraction, examination of optic disc. Those with <6/12 VA on presentation underwent best-corrected VA and dilated biomicroscopic ocular examination. RESULTS: 1317 subjects (633 men) had undergone surgery in one or both eyes. Of the 1788 operated eyes, 1099 (61%) had undergone intracapsular cataract extraction (ICCE) and 607 (34%) extracapsular surgery with an intraocular lens (ECCE+IOL). Presenting VA: 275 (15.4%) eyes: 6/12 or better; 253 (14.1) <6/12 >or=6/18; 632 (35.3%) 6/18 to 6/60; 85 (4.8%): 6/60 to 3/60; 528 (29.5%): <3/60. With "best" refractive correction, these values were: 563 (31.5%), 332 (18.6%), 492 (27.5%), 61 (3.4%), 334 (18.7%), respectively. Of the 1498 eyes with VA or=4 years before the survey. CONCLUSION: Almost a third of cataract operations result in a presenting VA of <6/60, which could be halved by appropriate refractive correction. This study highlights the need for an improvement in quality of surgery with a more balanced distribution of services.

Adult↗

PubMed1999

Pakistan National Diabetes Survey prevalence of glucose intolerance and associated factors in North West at Frontier Province (NWFP) of Pakistan.

AIM: To estimate the prevalence of non-insulin dependent diabetes mellitus (NIDDM) and impaired glucose tolerance (IGT) and their relationship with age and obesity in a population based survey in the rural areas of NWFP, Pakistan. SETTING: Three villages, Pawakai, Reghi and Jhagra in NWFP were the target areas. METHODS: Cluster sampling of 1035 adults aged 25 years and above (207 men, 828 women) was done. Oral glucose tolerance tests were performed and the diagnosis of diabetes and IGT was made according to WHO criteria. Height, weight and waist hip ratio of the study population were recorded. The Chi Square test was used to measure the association among the different variables. Basic demographic information from the subjects was collected by a physician using a standard questionnaire. RESULTS: The overall prevalence of NIDDM and IGT in both sexes was 11.1% and 9.4%. The sex-specific prevalence of diabetes was 9.2% in men and 11.6% in women. Advanced age, positive family history of diabetes and obesity were associated with higher rates of diabetes. In both sexes high Waist Hip Ratio (WHR) was more closely associated with diabetes than was high Body Mass Index (BMI). CONCLUSION: The prevalence of diabetes mellitus in rural areas of NWFP is high and almost similar to that of Sindh and Baluchistan.

Adult↗

PubMed1965

CHOLERA IN EAST PAKISTAN FAMILIES, 1962-63. PAKISTAN-SEATO CHOLERA RESEARCH LABORATORY.

The families of 85 cholera patients hospitalized during 1962-63 in Dacca District, East Pakistan, were studied in order to determine the relationship between familial and individual characteristics and the spread of the disease. Details of the circumstances, personal characteristics and medical history of the family members were recorded, and daily visits were made over a two-week period by a team of physicians and sociologists. Secondary cases were observed in 33 of the 85 families. Secondary attack rates were higher among children than adults. Spread of cholera within these families was suggested by the distribution of intervals between primary and subsequent cases, by the relationship between lengthy home stay of index cases and increased numbers of secondary cases, and by the effect of family structure on secondary attack rates.

Adult↗

PubMed1988