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Plant poisoning and oto-rhino-laryngology. Poisonous plants, growing or used in Europe and the United States.

Poisoning often affects the ear, nose, mouth and throat. Sialorrhea, stomatitis, oropharyngeal dryness, a burning sensation in the mouth, rhinitis and nasal septal perforation, hearing loss and vestibular disturbances can be the result of intoxications by poisonous plants, growing or used in Europe and the United States. This article has not the intention to be exhaustive, but to give a synopsis of this topic.

Hearing Disorders↗

Poisonous plants affecting livestock in Brazil.

Plant poisoning, together with rabies and botulism, are the main causes of death in adult cattle in Brazil. Estimates indicate that about one million head of cattle die annually through plant poisoning in this country. There are approximately 75 plants of practical importance to animal husbandry that have had their toxicity confirmed by experiments with the animal species affected under natural conditions. The great majority of these plants only occur in Brazil and neighbouring countries. A few of them are forage plants that can become toxic under certain conditions. In this review the poisonous plants of interest to animal husbandry of Brazil are divided according to the clinical-pathological picture they cause in cattle; only cyanogenic plants, plants that cause nitrate/nitrite poisoning and the ones that cause oxalate poisoning, are grouped according to their toxic principles. Plants and their toxic principles, or of which possible toxic compounds have been isolated, are listed.

Animal Diseases↗

Plant poisonings in children in the Czech Republic, 1996-2001.

Ingestion of or exposure to potentially poisonous plants is a relatively common presenting complaint in hospital paediatric departments, especially amongst toddlers. We present a retrospective study conducted to review the hospital admissions following acute childhood poisoning with plants in the Czech Republic over a 6-year period from 1996 to 2001. Six university hospital paediatric departments and two local hospital paediatric departments were involved in the study. Information and complete data on the cases were collected on the basis of all hospital medical records and internal hospital database outcomes. A total of 174 plant exposures were analysed to tabulate the list of top species involved in plant poisonings. The aims were to provide classification according to agent frequency, clinical presentations, severity of symptoms expressed, affected age groups and gender of patients and to evaluate the treatment according to patient outcome. The most frequent ingestions were of thorn apple seeds (14.9%), followed by dumb cane exposures (11.5%) and common yew (9.8%). Thorn apple, dumb cane, golden chain and raw beans caused the most serious symptoms. There were no fatalities reported out of the reviewed medical records. Complete data on plant poisoning in children from all over the territory of the Czech Republic are not available; however, we believe that the frequency of causes and the rank of plant species commonly involved are properly reflected in our study.

Adolescent↗

Plant poisoning in livestock. Management strategies for prevention.

Poisonous plants are a principal cause of economic loss to the US livestock industry. These losses are due to such things as deaths of livestock, abortions, photosensitization, debilitation and birth defects. Additionally, livestock producers and land managers are faced with such problems as fencing, loss of forage, altered grazing programs, and, in some instances, supplemental feeding programs and veterinary fees. Much can be done to prevent these losses if those involved know the poisonous plants growing on their ranges and the conditions under which the animal may be poisoned.

Animals↗

[Plant poisoning].

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Plant Poisoning↗

Poisonous plant vouchers.

Every published report of plant poisoning, whether experimental or accidental, should document plant identification. The essential elements are: complete botanical Latin name including species, specific epithet and author(s); name of the collaborating botanist who identified the plant; and herbarium and collection number of a voucher specimen from the exposure lot. Additional information to aid identification might include plant photographs, drawings, and descriptions.

Humans↗

Retrospective searching for poisonous plant vouchers.

Few published reports of plant poisoning, whether experimental or accidental, document vouchers. This can be rectified by retrospective location of vouchers through determination of a collaborating botanist or herbarium of deposit. An absolute voucher is referenced in the toxicology report. For a probable voucher the report does not identify an herbarium specimen, but the report and the specimen label or sheet agree on plant name, collector's name, collection date and place. A possible voucher is perhaps from the exposure lot, but was collected by the collaborating botanist at a somewhat earlier or later date than the exposure date. On the other hand, a supporting specimen was collected by the collaborating botanist but is not from the exposure lot. Vouchers and supporting specimens for some species of Asclepias tested for toxicity by CD Marsh and coworkers were found in the US National Herbarium at the Smithsonian Institution, Washington DC.

Data Collection↗

Economic impact of poisonous plants on the rangeland livestock industry.

Poisonous plants on rangelands cost producers and consumers upwards of $250 million annually in the U.S. These costs are attributable not only to livestock deaths and diminshed productivity related to plant poisoning, but also to the management costs associated with usage of forage in areas infested with poisonous plants. At present, even relatively small losses from plant poisoning can cause financial and economic impacts that threaten range enterprises, particularly those using public lands.

Animal Feed↗

Acute plant poisoning and antitoxin antibodies.

Plant poisoning is normally a problem of young children who unintentionally ingest small quantities of toxic plants with little resulting morbidity and few deaths. In some regions of the world, however, plant poisonings are important clinical problems causing much morbidity and mortality. While deaths do occur after unintentional poisoning with plants such as Atractylis gummifera (bird-lime or blue thistle) and Blighia sapida (ackee tree), the majority of deaths globally occur following intentional self-poisoning with plants such as Thevetia peruviana (yellow oleander) and Cerbera manghas (pink-eyed cerbera or sea mango). Antitoxins developed against colchicine and cardiac glycosides would be useful for plant poisonings--anti-digoxin Fab fragments have been shown to be highly effective in T. peruviana poisoning. Unfortunately, their great cost limits their use in the developing world where they would make a major difference in patient management. Therapy for some other plant poisonings might also benefit from the development of antitoxins. However, until issues of cost and supply are worked out, plant antitoxins are going to remain a dream in many of the areas where they are now urgently required.

Acute Disease↗

History of USDA poisonous plant research.

Research on poisonous plants was instituted by the United States Department of Agriculture (USDA) as a result of serious livestock poisoning by plants as the pioneers moved west in the mid-to-late 1800s and early 1900s. Historical records indicate the USDA began poisonous plant research in 1894 under the direction of Mr. V. K. Chestnut, a botanist (Table 1 briefly summarizes those who have directed poisonous plant research from the inception to the present). Mr. Chestnut's responsibility (1894-1904) was primarily administrative, although he did extensive field work in Washington and Montana. Temporary field stations were set up to study specific poisonous plant problems. These included field stations at Hugo and Woodland Park, Colorado, and Imperial, Nebraska (1905-1909), to study locoweed; Gunnison, Colorado (1910-1912), to primarily study larkspur; and Greycliff, Montana (1912-1915), to study the poisonous plants of the Yellowstone Valley. Dr. Rodney True replaced Mr. Chestnut in 1904 and in 1905 hired Dr. C. D. Marsh (1905-1930) to establish the temporary field stations listed above. In 1915 a permanent facility was established at Salina, Utah, under the direction of C. D. Marsh who remained in charge until 1930 when he retired; he was followed by A. B. Clawson until 1937 when Dr. Ward Huffman was placed in charge. Research on poisonous plants was located at the Salina Experiment Station until 1955 when the station was closed and the laboratory moved to the campus of Utah State Agricultural College at Logan, Utah, where it is currently located. Dr. Wayne Binns was hired as the director of the laboratory in 1954 and retired in 1972. In 1972 Dr. Lynn F. James, who joined the PRPL staff in July 1957, was appointed as Research Leader and presently directs the research at the Poisonous Plant Research Laboratory.

Academies and Institutes↗

Poisonous plants of Brazil.

Poisonous plants are a serious problem for cattle breeding in Latin America. Owing to the extensive pastural agriculture it is not possible to exterminate such plants. Apart from the considerable financial loss to individual farmers and the national economy owing to dead animals, there is the important question of how far the meat and milk of chronically poisoned animals are a health risk for humans. The toxins of the most important toxic plants from Brazil are described.

Animals↗

Plant poisonings in children.

1. Plant poisonings comprise 5% of all hospitalizations due to poisonings in children and plant inquiries to Poison Information Centre consist about 28% of calls concerning children. 2. A search of 71 cases of hospitalization due to plants in a 5 year period obtained from two children's hospitals in Helsinki were reviewed and 105 plant inquiries concerning poisonings among children to the Poison Information Centre in a 6 month period were studied. 3. The most frequent plant poisonings involved lily-of-the-valley, dumb cane and cotoneaster plant. Only 11% of the cases treated in hospital were evaluated to be unequivocal poisonings. 4. Mezereon, snowberry, cotoneaster plant, honeysuckle, and woody nightshade caused the most serious symptoms. Symptoms in mezereon poisoning were increased saliva excretion, haematuria and diarrhoea in a 1.2-year-old girl. Snowberries caused a semicomatose state and difficulty in urination, cotoneaster caused severe stomach ache, honeysuckle abudant gastrointestinal symptoms and muscle cramps, and nightshade led to prolonged high fever and sweating. 5. It appears that almost all plant poisonings could be treated with medical charcoal. Gastric evacuation is seldom required.

Child↗