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The occurrence of Poland and Poland-Moebius syndromes in the same family: further evidence of their genetic component.

The combination of Moebius and Poland anomalies is rarely described in the literature. Some authors believe that this association is an independent syndrome, while others propose that Poland, Moebius and Poland-Moebius are a spectrum of the same condition. Here we report a family where a child has Poland-Moebius syndrome and an aunt is affected with Poland anomaly. This probably represents the second report of possible autosomal dominant transmission of Poland-Moebius syndrome. The presence of contralateral triphalangeal thumb in the proband and in other members of the family can be explained by chance alone or, alternatively, by a pleiotropic expression of this gene.

Adolescent↗

Studies on the morphology of colonies of bacilli of BCG-Poland substrain. I. The influence of iron on the type of BCG-Poland colonies.

The influence of iron concentration in Sauton's medium solidified with agar on the type of colonies of BCG-Poland substrains, BCG-Rio de Janeiro, BCG-France, BCG-Denmark and BCG-Japan substrains has been examined. Of all the studied BCG substrains only the BCG-Poland substrain formed rough (R) and smooth (S) colonies. In the investigated substrains rough colonies became smaller with the decrease of iron concentration but they retained their characteristic surface roughness. The smooth colonies which in the same conditions appeared only in BCG-Poland substrain did not display such dependency on iron concentration. When the incubation period was prolonged secondary rough colonies appeared among the smooth ones, regardless of the iron concentration in the medium.

BCG Vaccine↗

Pectoralis major defect and Poland sequence in second cousins: extension of the Poland sequence spectrum.

We report on a patient with congenital absence of the left pectoralis major muscle, whose second cousin had the full Poland sequence. This suggests that isolated pectoralis major muscle defect should be included in the spectrum of anomalies characterized as the Poland sequence, postulated to result from disruption of blood supply in the embryonic subclavian and vertebral arteries, the site and degree of obstruction determining the sites and severity of the resulting anomalies. Very few cases are familial; in these the family pattern is compatible with an autosomal dominant mutant gene with reduced penetrance or delayed mutation.

Humans↗

Poland-Moebius syndrome in a boy and Poland syndrome in his mother.

A 4 4/12-year-old boy with the Poland-Moebius syndrome, whose mother had the POland syndrome, is presented. This is the first report of the occurrence of both syndromes in the same family, suggesting that they are expressions of the same autosomal dominant gene.

Adolescent↗

[Treatment in XIIth c. Poland according to medical writings of Nicholas of Poland].

The authors present the person of Mikolaj of Poland, a thirteenth century doctor, connected with the Princes of Pomerania and Greater Poland, educated in France, and known from his two major writings, Antipocras (Anti-Hypocrates) and Experimenta. On the background of medieval medicine, the methods of healing he suggested appear as unusual and unconventional. He healed with amulets, mud, dung, river and sea water, frogs, moles, vipers, flies and worms. Using them, he produced powders, pills, ointments and oils which were to have outstanding healing results. They were to be used in lithiasis, skin irritations, nephritis, hepatitis, deafness, epilepsy, and toothache. Women might use them as cosmetics, too. Considering thirteenth century medicine, Mikolaj with no doubts represents medieval medical "empiry", creating an interesting alternative against official standards binding doctors of that time.

History, Medieval↗

[Trauma and poisoning in children and adolescents in Poland from 1980-1985 in the light of data on hospitalization. I. Hospitalization of children and adolescents in Poland for trauma and poisoning according to demographic features].

The frequency of hospitalization of children and adolescents for traumas and intoxications in Poland in the years 1980-1985 was analysed on the basis of data obtained from the All-Polish Study of General Morbidity. Trauma and intoxications were the causes of about 16% of all hospitalizations in the age group 0-19 years. In the age group 15-19 years they were the most frequent causes of hospital stay. In all age groups the indices of hospitalization of children and adolescents in Poland were lower than in other countries. The most frequent causes of hospitalization for trauma and intoxication were in boys superficial lesions and contusions, and in girls--intoxications. In both sex groups fractures of extremities, cranial trauma and burns were frequent causes of hospitalization. Boys were hospitalized more frequently than girls, and this difference increased with age. No significant differences were found between children and adolescents from urban and rural areas in the total hospitalization rates, but some differences were noted between these areas in groups with various diagnoses.

Adolescent↗

Studies on the morphology of colonies of bacilli of BCG-Poland substrain. II. Dissociation of BCG-Poland substrain on Löwenstein-Jensen egg medium.

The dissociation of colonies of the substrain BCG-Poland on Löwenstein-Jensen medium has been studied. It had been stated previously (Lipińska and Rzucidło, 1974) that BCG-Poland substrain undergoes a process of dissociation which manifests itself in the appearance of smooth colonies alongside typical rough colonies. Attempts have been made to obtain pure culture of both colony types. Pure cultures composed of smooth or rough colonies respectively were obtained. The morphology and diameter of the smooth colonies depended on the size of the seed inoculum spread on the medium.

BCG Vaccine↗

Epidemiology of childhood bacterial meningitis in Poland. Incidence of bacterial meningitis with special reference to Haemophilus influenzae type b among children 0-59 months old in the former Kielce and Bydgoszcz districts in Poland in 1998-1999.

Population based surveillance was undertaken to assess the incidence of meningitis caused by Haemophilus influenzae type b in children 0-59 months old in Kielce and Bydgoszcz districts in Poland in 1998 and 1999. The cases were prospectively identified in pediatric and neuroinfection wards of local hospitals where all cases of children with suspected meningitis are referred in both districts. The mean annual incidence of meningitis caused by Haemophilus influenzae type b in children 0-59 months old in Kielce district during the study period was estimated at 3.1 per 100,000 per year (10.3% of cases of bacterial meningitis with confirmed etiology). In Bydgoszcz district, the annual incidence was 9.7 per 100,000 (50% of confirmed cases). These estimations are lower than reported in most Western European countries before the immunization against Hib was introduced. Small numbers of Hib vaccinations reported from both districts do not seem likely to have influenced the data significantly.

Child, Preschool↗

Síndrome de Poland. Presentacíon de un caso. [Poland's syndrome. A case report].

A case of Poland's syndrome in a 19-year-old male is briefly described. This syndrome is characterized by congenital absence of the pectoralis major and minor muscles as well as homolateral brachysyndactyly. The etiology is unknown. Surgical repair is aimed at constructing a functional hand. Chest deformities usually does not require surgery except in cases of lung herniation or breast hypoplasia.

Adult↗

[Trauma and poisoning in children and adolescents in Poland from 1980-1985 in the light of data on hospitalization. II. Territorial differences in hospitalization of children and adolescents in Poland for trauma and poisoning].

The differences between various provinces in the frequency of hospitalizations of children and adolescents in Poland in the years are presented. The data were obtained from the All-Polish study of General Hospital Morbidity. The provinces with the highest hospitalization rates included those of Wałbrzych, Jelenia Góra, Suwałki, and the lowest rates were in the Province of Gdańsk and Province of Rzeszów. A relationship was noted between the number of hospitalized patients and the duration of hospital stay--with longer hospitalization in the areas with low number of such cases.

Adolescent↗

[Trauma and poisoning in children and adolescents in Poland from 1980-1985 in the light of data on hospitalization. III. Hospital mortality of children and adolescents in Poland from trauma and poisoning].

The hospital mortality of children and adolescents hospitalized for traumas and intoxications in Poland in 1980-1985 is discussed. Only 20% of deaths due to these causes occurred in hospitals, the remaining deaths were on the scene of accident or in the home of the patient. The hospital mortality was similar in boys and girls although the frequency of hospitalization for trauma and intoxication was twice as high in boys as in girls. The main causes of death in hospital were cranial trauma, spinal fractures, internal organ injuries, burns and poisoning. With the exception of poisoning these causes produced a higher mortality in hospital of young individuals from rural areas than those from urban centres. Without respect to the place of residence nearly 40% of hospital deaths occurred on the first day in hospital.

Adolescent↗

[Promotion program for breast feeding in Poland. II. Analysis of the breast feeding situation in Poland].

Assessment of breast-feeding situation in Poland was based on three kinds of nation-wide surveys conducted in 1988: newborn feeding and breast feeding routines in maternity wards epidemiology of breast-feeding and other feeding methods in first six months of infant life KAP study among MCH professionals The major findings of the surveys were: conflicting with lactation maternity wards routines especially: very initiation of breast-feeding, administration of liquids and formulas, rigid feeding schedule, separation of newborns from the mothers too early supplantation of breast-feeding lack of current breast-feeding knowledge among MCH professionals.

Breast Feeding↗