PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “POULTRY DISEASES”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources

Vaccines for List A poultry diseases: emphasis on avian influenza.

Various vaccine technologies have been shown experimentally to be effective for immunization against avian influenza (AI) virus and include conventional inactivated oil-based whole AI virus, vectored virus, subunit protein and DNA vaccines. Vaccine-induced protection is based upon antibodies produced against the surface glycoproteins, principally the haemagglutinin, but also the neuraminidase. This protection is specific only for individual subtypes of haemagglutinin (H1-15) and neuraminidase (N1-9) proteins. AI vaccines protect chickens and turkeys from clinical signs and death, and reduce respiratory and intestinal replication of a challenge virus containing homologous haemagglutinin protein. Many of the vaccines are effective if given as a single injection and provide protection for greater than 20 weeks. Protection has been demonstrated against both low and high doses of challenge virus. Furthermore, subtype H5 AI vaccine has been shown to provide protection against heterologous H5 strains with 89.4% or greater haemagglutinin deduced amino acid sequence similarity and isolated over 38 years. Currently, inactivated whole AI virus vaccines and a fowl pox-vectored vaccine with AI H5 haemagglutinin gene insert are used commercially in various countries of the world. These vaccines have some disadvantages associated with the labour requirements for parenteral administration. However, an experimental recombinant Newcastle disease virus vaccine with an AI haemagglutinin gene insert shows some promise as a low cost, mass administered aerosol vaccine. A critical issue for the use of vaccines in the field is the need to differentiate vaccinated birds from those infected with the field virus. Differentiation is necessary for outbreak surveillance and trade. The use of AI vaccines varies with individual countries and for different AI virus subtypes.

Animals↗

National surveillance of poultry diseases in Lebanon.

From 1992 to mid-1996, a national survey of poultry diseases in Lebanon was conducted. This surveillance included meat breeder, layer breeder, commercial layer and chicken broiler flocks. The history, signs, lesions and laboratory tests of poultry were used in the diagnosis of prevalent poultry diseases. Culture techniques were used to screen for bacterial diseases; serological techniques and, to a lesser extent, culture techniques were used to diagnose viral diseases; and both serological and culture techniques were used to diagnose Mycoplasma infections. The outbreaks of diseases detected in broiler breeder flocks and the number of such flocks experiencing these diseases were as follows: femoral head necrosis (6), egg-drop syndrome (3), reovirus-associated malabsorption syndrome (3), synovitis (Mycoplasma synoviae infection) (7), swollen head syndrome (SHS) (3), tenosynovitis (viral arthritis) (1), lymphoid leukosis (3), avian encephalomyelitis (1), fowl pox (1) and aortic rupture (1). The disease outbreaks detected in layer breeders were as follows: SHS (2), bumble foot (2), egg-drop syndrome (3) and avian infectious bronchitis (IB) (1). The disease outbreaks detected in commercial layer flocks were as follows: egg-drop syndrome (5), avian infectious laryngotracheitis (2), avian IB (nephrogenic strain) (1), malabsorption (1), avian tuberculosis (Mycobacterium avium) (1), Marek's disease (1), fowl pox (1), Salmonella enterica subsp. enterica Enteritidis infection (1), salpingitis (1) and Heterakis gallinae infestation (1). The disease outbreaks detected in broiler flocks were as follows: colibacillosis (40), infectious bursal disease (Gumboro disease) (15), malabsorption syndrome (8), avian infectious laryngotracheitis (8), paratyphoids (salmonellosis) (7), femoral head necrosis (8), SHS (6), avian mycoplasmosis (Mycoplasma gallisepticum infection) (6), synovitis (7), avian IB (6), botulism (1), avian encephalomyelitis (1) and gangrenous dermatitis (1). Diseases which occurred and which were reported for the first time in Lebanon were as follows: bumble foot, femoral head necrosis, avian IB (nephrogenic strain), malabsorption syndrome and SHS. This surveillance helped to establish baseline data concerning the predominant poultry diseases in Lebanon. Such information is a prerequisite for future regional and international collaboration to identify the source of the aetiological agents and to control their spread to neighbouring countries.

Adenoviridae Infections↗

Gordon Memorial Lecture. Problems and crusades: a history of poultry disease research in the United Kingdom.

1. Poultry disease research in the UK began recognisably in the 1920s, in consequence of the development of a national poultry industry of economic importance. 2. Increasing disease problems during the 1930s revealed the need for more research, resulting notably in the growth of the Poultry Department of the Central Veterinary Laboratory and the establishment of Houghton Poultry Research Station. 3. Continued growth of the egg industry and the introduction of the broiler industry in the 1950s stimulated increased disease research, much of it publicly funded, during the following two decades. 4. Changing government attitudes to agricultural research in the 1980s brought about far-reaching changes to the funding, organisation, nature and amount of disease research conducted. Arrangements for such research continue to evolve.

Agriculture↗

Molecular typing of isolates of Clostridium perfringens from healthy and diseased poultry.

The bacterium Clostridium perfringens can cause both clinical and subclinical disease in poultry. To study the pathogenesis and epidemiology of disease caused by C. perfringens, methods for typing its various strains need to be evaluated. C. perfringens isolates from healthy and diseased poultry from different parts of Sweden were analysed by polymerase chain reaction (PCR) in order to establish the presence of alpha-, beta-, beta2-, epsilon -, iota- and enterotoxin genes. In order to subtype C. perfringens isolates, the two methods amplified fragment length polymorphism (AFLP) and pulsed field gel electrophoresis (PFGE) were compared on 21 C. perfringens isolates from 10 different farms. In a second study, 32 isolates of C. perfringens type A from three broilers from a healthy flock reared without ionophorous anticoccidials were subtyped by PFGE. All 53 isolates analysed with PCR belonged to the toxin type A of C. perfringens, with the gene coding for alpha-toxin production. Two isolates possessed the beta2-gene as well, but none had the other toxin genes. Both AFLP and PFGE differentiated 21 strains into 10 different subtypes. This differentiation correlated closely with the origins of the isolates. Unique subtypes were isolated from seven farms. Only isolates from birds of one farm demonstrated more than one subtype of C. perfringens. The subtyping of the isolates from a healthy flock showed that each bird carried two to three different subtypes and two different subtypes were found in the same kind of tissue sample in four cases. Three of the four different subtypes found in this study were new, compared with the first study. AFLP and PFGE were found to be equally suitable for subtyping of C. perfringens isolates. The wide variation in subtypes in the healthy broilers could be the result of the antibiotic-free rearing of these birds.

Animals↗

Rapid serological profiling by an immunocomb-based dot-enzyme-linked immunosorbent test for three major poultry diseases.

An immunocomb-based dot-ELISA, employing specially designed apparatus, was used to measure the antibody status for the three major poultry diseases--Newcastle disease, infectious bursal disease and infectious bronchitis--in single test sera. Positive samples could be classified into strong, moderate and weak positives by comparison with the colour reaction given by known strong and weak positive serum controls. The simultaneous dot-immunobinding assay gave reproducible results and allowed considerable savings on the cost of reagents compared to liquid ELISA. The antigen-coated immunocomb can be stored under refrigeration and the test can be performed rapidly under field conditions by trained personnel.

Animals↗