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At least 19 recordsLinked to original sources

[Preventive effect of dipropylacetamide in bipolar manic-depressive psychoses].

Dipropylacetamide (DEPAMIDE) was administered to 60 patients with bipolar manic-depressive psychoses. The dosage was 900 mg per day, administered orally. In 5 (8%) of the patients gastrointestinal disorders were observed. Administration of lithium carbonate results in undesirable side-effects in 50% of the cases. Our clinical experience shows dipropylacetamide to have a considerably slighter toxic effect on the human organism than lithium carbonate. We regard Dipropylacetamide (DEPAMIDE) as a valuable and significant addition in the prophylaxis of affective disorders, notably bipolar manic-depressive psychoses.

Anticonvulsants↗

[Factors influencing the clinical picture, course and effectiveness of therapy in patients with manic-depressive psychoses].

The long lasting (5-8 years) clinical observations of 496 patients suffering from manic-depressive psychoses had allowed the authors to distinguish some factors which influence (in a positive and negative way) the clinical features and therapeutic effectiveness as well as to follow the origin of psychoses. The attached specification of these factors is not complete, further tests and investigations are needed.

Adolescent↗