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At least 19 recordsLinked to original sources

Nonlinear filters applied on computerized axial tomography: theory and phantom images.

New nonlinear image processing techniques, in particular smoothing based on the understanding of the image, may create computerized tomography (CT) images of good quality using less radiation. Such techniques may be applied before the reconstruction and particularly after it. Current CT scanners use strong linear low-pass filters applied to the CT projections, reducing noise but also deteriorating the resolution of the image. The method in this study was to apply a weak low-pass filter on the projections, to perform the reconstruction, and only then to apply a nonlinear filter on the image. Various kinds of nonlinear filters were investigated based on the fact that the image is approximately piecewise constant. The filters were applied with many values of several parameters and the effects on the spatial resolution and the noise reduction were evaluated. The signal-to-noise ratio of a high-contrast phantom image processed were compared with the nonlinear filter, with the SNR of the phantom images obtained with the built-in CT linear filters in two scanning modes, the normal and the ultra high resolution modes. It was found that the nonlinear filters improve the SNR of the image, compared to the built-in filters, about three times for the normal mode and twice for the UHR scanning mode. The most successful filter on low-contrast phantom image was applied and it also seems to lead to promising results. These results seem to show that applying nonlinear filters on CT images might lead to better image quality than using the current linear filters.(ABSTRACT TRUNCATED AT 250 WORDS)

Humans

Image segmentation in digital mammography: comparison of local thresholding and region growing algorithms.

Local thresholding and region-growing algorithms are developed and applied to digitized mammograms to quantify the parenchymal densities. The algorithms are first evaluated and optimized on phantom images reflecting varying image contrast, X-ray exposure conditions, and time-related changes. The difference between the segmentation results of the two techniques is less than 6% on the phantom images and 11% on the mammograms. The agreement between the computerized procedures and a manual one is in the range of 74-98%, depending on the breast parenchymal pattern and segmentation algorithm. The results show that computerized parenchymal classification of digitized mammograms is possible and independent of exposure.

Algorithms

Preliminary evaluation of a digital system for rotational panoramic radiography.

A prototype system for direct digital panoramic radiography has been evaluated with respect to density, contrast, magnification, distortion, resolution, and overall image quality. Density and contrast depend on detector calibration and may be modified by the display system or by digital processing of the captured image. Variation of magnification in the horizontal and vertical dimensions gives rise to distortion phenomena that are identical to those encountered in film-based systems. Resolution in the vertical dimension is determined by the pitch of the detector elements. In the horizontal dimension, resolution is limited by the effective width of the detector elements. To evaluate the clinical acceptability of the images, radiologists and general practice residents were asked to assess the perceptibility of important radiographic landmarks in film-based and digital images of both a radiographic phantom and a patient. The digital system performed on a par with film in the representation of normal morphologic structures of the clinical human subject whereas more differences were apparent in the phantom images. The general practice residents consistently rated the digital images higher than their radiologist counterparts did. No consistent trends were found to indicate any inherent deficiencies of the digital system in the depiction of any one area. The results indicate the promise of direct digital acquisition as a method of panoramic imaging.

Evaluation Studies as Topic

Whole-body single-photon emission computed tomography using dual, large-field-of-view scintillation cameras.

A whole-body single-photon emission computed tomography system (SPECT) consisting of two large-field-of-view scintillation cameras mounted on a rotatable gantry, a minicomputer and a display station has been designed, constructed and evaluated. In its usual mode of operation, eleven contiguous transverse sections, each 12.5 or 25 mm thick, are reconstructed from projection data acquired during a single, continuous 360 degree rotation lasting from 2 to 22 min. A generalised filtered and weighted backprojection algorithm is used to reconstruct data obtained with conventional parallel-hole collimators in the case of body scanning, or with specially designed fan beam collimators in the case of centrally positioned organs. A simple, yet effective, correction is used to compensate for the effects of gamma ray attenuation within the patient. In addition to providing transverse section images, the system is capable of simultaneous acquisition of opposed conventional scintigrams, the reconstruction of longitudinal section images, and the acquisition of gated cardiac transverse sections. Resolutions in the reconstructed images are typically 15 mm for body scans and 11 mm for brain scans, with only slight variations in sensitivity and resolution within the image. Phantoms and clinical data demonstrate that the SPECT system generates high quality section images while maintaining most of the flexibility of normal scintillation cameras, with the added advantage of dual heads.

Tomography, Emission-Computed

Demonstration of megavoltage and diagnostic x-ray imaging with hydrogenated amorphous silicon arrays.

Flat-panel imagers consisting of the first large area, self-scanning, pixelated, solid-state arrays made with hydrogenated amorphous silicon (a-Si:H) are under development by the authors for applications in diagnostic x-ray and megavoltage radiotherapy imaging. The arrays, designated by the acronym MASDA for multi-element amorphous silicon detector array, consist of a two-dimensional array of a-Si:H photodiodes and thin-film transistors and are used in conjunction with scintillating materials. Imagers utilizing MASDA arrays offer a variety of advantages over existing technologies. This article presents initial megavoltage and diagnostic-quality x-ray images taken with several such arrays including the first examples of anatomical-phantom images. The external readout electronics and imaging techniques required to obtain such images are outlined, the construction, operation, and advantages of the arrays briefly reviewed, and the future potential of this new technology discussed.

Diagnostic Imaging

Relative properties of tomography, K-edge imaging, and K-edge tomography.

The properties of tomography, K-edge imaging, and K-edge tomography are discussed in relation to the imaging of small concentrations of elements such as iodine and xenon and are compared by means of phantom images. It is demonstrated that the complementary selectivities provided by depth and energy subtraction are combined in K-edge tomography. Using a three-spectrum subtraction technique, the iodine difference signal predicted by computer calculations is on the order of 8000 times that of an equal concentration fo bone. The corresponding ratio in tomography without energy subtraction is 20:1. It is argued that K-edge tomography can successfully eliminate artifacts due to tissue inhomogeneities which presently enable 0.6% variations in tissue attenuation to mimic minimum detectable iodine signals in conventional computed tomography. Various instrumentation possibilities and energy subtraction techniques are discussed.

Models, Structural

Phantom evaluation of imaging modalities for silicone breast implants.

RATIONALE AND OBJECTIVES: Recent concern regarding possible adverse effects from silicone breast implants has increased the role of radiologists in assessing augmented breasts. The authors compare the commonly available imaging modalities in evaluating the intact silicone implant as well as free silicone in the adjacent tissue. METHODS: A contrast resolution phantom and breast of veal phantom were tested. Fat was used as a reference material. The phantoms were imaged with xeromammography, film-screen mammography, ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI). Proton MRI spectroscopy also was performed on fat, silicone, water, and water/gelatin samples. The consensus of two radiologists determined whether free silicone was present. RESULTS: CT and MRI provided the best images of the implant and the free silicone. Several features of MRI were useful: spin-density scans and the fast low-angle shot (FLASH) and fast imaging with steady-state precision (FISP) techniques provided excellent resolution, a consistent chemical shift artifact appeared around the silicone, and frequency selective pre-saturation techniques resulted in marked suppression of the silicone. CONCLUSION: Additional testing in a more realistic setting, breast coil design, and improvement of various MRI techniques, particularly the frequency selective pre-saturation techniques, all appear promising in evaluating breast implants, the presence of free silicone, and the adjacent tissues.

Breast

Discrimination of phantom hand sensations elicited by afferent electrical nerve stimulation in below-elbow amputees.

The necessity for a sensory feedback system that would enhance patient acceptability of motorized hand prostheses is now generally acknowledged. Afferent electrical stimulation of the nerves in the amputation stump can convey sensory feedback from prostheses with the advantage of eliciting sensations in the phantom image of the lost hand. Experiments with percutaneous nerve stimulation of the amputation stump in below-elbow amputees showed that with stable electrode conditions, amplitude modulated stimulation was better than frequency modulated stimulation in terms of accuracy, delay, and transinformation both with intermittent and uninterrupted stimulation. With unstable electrode conditions, different results were noticed, since amplitude modulated stimulation is very sensitive even to minor changes in electrode position. It is concluded that afferent electrical nerve stimulation with adequate training and stable electrodes had characteristics of accuracy, transinformation and delay which are good enough to make it a suitable method of conveying information in a prosthesis feedback system.

Adult

Tomogram degradation due to eye shielding and collimation.

Phantom-image, line-pair resolution and anterior eye exposure have been measured to determine the optimum collimation and eye shielding for petrous temporal tomography. Small round collimation and 0.5-1.0-mm lead equivalent eye shields are recommended. This reduces eye exposure to 10% of the usual dose without changing line-pair resolution.

Eye

[Fracture of skull-comparative study of conventional and computer-assisted roentgenological examination (author's transl)].

Using a skull like phantome imaging characteristics of conventional x-ray technique and computerized tomography are compared. The contrast transfer function of x-ray films proofs to be superior, whichis due to overrange artefacts found in computerized tomography. Only 8 out of 50 skull fractures diagnosed by plain film technique were identified on computer-tomograms. Even though CT technique is excellent for the detection of intracranial lesions, fractures are more easily seen on conventional films. This is especially important for analysing size and site of impression fractures.

Humans

Essential knowledge about pitfalls in tomography.

Tomographic cut is not synonymous to a roentgenogram of an anatomic cut. Blurring is inherent in the tomogram, and the edges do not appear as sharp as in the conventional roentgenogram. Part of the contrast is lost in tomography. Therefore, when tissue contrast is low, or when we intend to see an entire structure in one cut, zoneography is preferred. On the other hand, when many details are crowded in a small area and/or when the tissue contrast is high, a thin section tomography is indicated. Proper knowledge of the level of area of interest (focal plane) and proper spacing of the cuts decrease radiation and expenses. The Law of Tangent, namely, "The edge of a structure should be momentarily parallel to the beam at the focal plane, in order to show on the film," is an essential part of every tomographic study. The Law of Tangent applies equally to spheres and other curved surfaces. The effective tomographic angle is the angle described by the tube during exposure. The thickness of the cut depends on the effective tomographic angle. Prior viewing of conventional roentgenogram and proper knowledge of the mechanism of parasitic and phantom images help us to avoid mistaking these images as real structures.

Axis, Cervical Vertebra

A physiologic regurgitant cardiac valve phantom for magnetic resonance imaging or color Doppler ultrasound study.

Noninvasive imaging has proven successful in the evaluation of valvular heart disease; primarily with magnetic resonance imaging (MRI) and color Doppler ultrasound (CFM). However, the relationship between the morphology of regurgitant flow in MRI and CFM, as a function of hemodynamic parameters (chamber pressure difference, lesion size, compliance, etc.) is not understood. The goals for this work were: 1) to develop a computer-controlled regurgitant cardiac valve phantom, compatible with artifact-free CFM and MR imaging, 2) to create regurgitant lesions in the phantom which appear similar to those detected clinically, 3) to produce and measure physiologic pressure differences between chambers, compliances, and regurgitant fractions as seen in mild, moderate, and severe regurgitation. Mean chamber pressure differences ranged from 43-142 mmHg over the range of diseases simulated. Similarly, regurgitant flow rates ranged from approximately 0.54-18.6 L/min. Compliance values ranged from 0.83 to 21.95 cc/mmHg. No coherent or incoherent artifacts were observed in MRI or CFM images. Images show a high degree of similarity to regurgitant lesions detected with each modality, confirming that all design goals were met. The system should allow extensive comparative analysis of Doppler ultrasound and MRI flow jets under a wide range of controllable hemodynamic conditions in future experiments.

Aortic Valve Insufficiency

Influence of matrix size, vessel shape, vascular diameter, flow velocity, course of vessels on MR angiography.

Basic experiments were done to examine the influence of the extent of curve, direction of flow, vascular diameter, velocity of flow, and course of vessels on MR angiography. In the first experiment, two phantoms were constructed of vinyl tubing, a hairpin type and one with tubes bent to varying degrees. These phantoms were imaged in two matrices, different FOV, and of various velocities with a 1.5 Tesla system. Images of a normal volunteer were also obtained. In studies of the hairpin phantoms, a low intensity artifact appeared at the curve position, and the edge became fuzzy when the flow was perpendicular to the phase encoding direction. These phenomena were more apparent with a smaller matrix, smaller FOV, more gentle angle, larger diameter, and faster flow; in other words the component along the direction was dominant. In the phantom that used bent tubes, another low intensity artifact appeared on the medial side of the outflow portion. The results obtained from the volunteer corresponded well to those from the basic experiments. It was thought that the profile of flow was not well demonstrated due to the coarse matrix. In the second experiment, water flowed at various speeds through three-dimensional phantoms that were made of vinyl tubes of various diameters and directions. The phantoms were imaged with two- and three-dimensional time of flight and phase contrast angiography. The lower limits of detection of the phase contrast method were almost the same. In the coronal plane, the lower limit decreased to 2.5 mm for arteries and 9.5 mm for veins.(ABSTRACT TRUNCATED AT 250 WORDS)

Blood Flow Velocity

[Development of a gel phantom for dose distributions by MR imager].

We reported a method of determining spatial dose distributions in tissue-equivalent phantoms using nuclear magnetic resonance imaging. To make a gel phantom, a cross-linked dextran gel (Sephadex G-200) was used as fixation agent of a ferrous sulphate solution. Although high quality images are obtained, the cost is very expensive to make the gel. We developed a new gel which is combined with an extra water absorbent polymer (Sumikagel N-100) and Sephadex G-200. The gel permits the determination of dose distributions for three dimensional treatment planning.

Ferrous Compounds

X-ray scatter data for diagnostic radiology.

The ratio of the scattered to the total X-ray fluence (scatter fraction) at the centre of the image plane for X-rays transmitted through polystyrene phantoms has been measured for X-ray energies of 32 and 69 keV, X-ray beam diameters from 4 to 40 cm, phantom thicknesses from 5 to 30 cm and phantom-to-image-plane separations from 0.3 to 40 cm. The experimental values for this ratio have less than a 10% variation for these two X-ray energies and the experimental data show good agreement with Monte Carlo calculations and available experimental results for low atomic number materials. Based on these results, simple curves are generated which give estimates (+/- 10%) of the scatter fraction for all combinations of the geometric parameters encountered in diagnostic radiology.

Models, Biological