Results for “Phytotherapy”

Conservative therapy of benign prostatic hypertrophy comprises the administration of oestrogens, gestagens, androgens and anti-androgens. Phytodrugs, which contain an extract of Sabal serrulatum or Pygeum Africana as active substance are without side effects and are, therefore, being used increasingly. 74 patients with irritable or obstructive bladder symptoms due to benign prostatic hypertrophy were treated with a phytodrug (Sabal serrulatum) or with testosterone throughout a period of three months. In group one (20 patients given phytodrugs and 10 patients given testosterone) clinical symptoms and measurements of residual urine, residual urine quotient, bladder capacity, micturition pressure and maximum urethral closure pressure were recorded at the beginning and at the end of therapy. In group two 28 patients were treated with the phytodrug in the first and third months with an intervening placebo trial lasting four weeks and 16 patients were given testosterone. Clinical symptoms and uroflow and residual urine only were charted in this group. None of the patients in either group showed an improvement in the urodynamic parameters of obstruction, but all patients felt a subjective alleviation of their symptoms.

Aged↗

PubMed1976

[Folk medicine, experience therapy, a component of modern therapeutics?].

Empirical medicine has three main supporting pillars: physical treatment, dietetics and phytotherapy. In this area of medicine, a number of therapeutical methods have been evolved which stand up to investigations employing scientific criteria, and which, in consequence, have become officially recognized by medical science. Examples are: diet rich in bulkage, digitalis, products of Papaver somniferum (Poppy) and salicylates. The acceptance of phytotherapeutic agents into the drug armamentarium of scientific medicine presupposes the availability of test methods suitable to demonstrate their effectiveness. Quite a number of remedies that have always been firmly anchored in empirical medicine, but which was applied regularly only by the nature healer, have suddenly, in the light of new test methods, been shown to be effective medicines; thus, for example, onions and garlic are good for thrombotic processes and hyperglycaemia, carminatives for sphincter spasms in the gastrointestinal tract, and alcohol is an appetite-stimulating stomachic. This fact, the limited applicability of the information obtained from animal experiments, and the further fact that even test results obtained in human subjects cannot be applied on a world-wide basis, exhort us to take care not to subscribe to an all-too apodictic classification of therapeutic measures into effective and noneffective. A further point for consideration is that the administration even of what is only a supposed remedy, can trigger or promote healing simply on the strength of the action of the physician. Scientific thinking is an indispensible precondition of the physician's activity--to consider it as the beginning and end of all things medical, however, is simply to demonstrate a narrowness of outlook.

Asthma↗

PubMed1976

[Treatment of primary chronic polyarthritis in special cases].

Empirical medicine has three main supporting pillars: physical treatment, dietetics and phytotherapy. In this area of medicine, a number of therapeutical methods have been evolved which stand up to investigations employing scientific criteria, and which, in consequence, have become officially recognized by medical science. Examples are: diet rich in bulkage, digitalis, products of Papaver somniferum (Poppy) and salicylates. The acceptance of phytotherapeutic agents into the drug armamentarium of scientific medicine presupposes the availability of test methods suitable to demonstrate their effectiveness. Quite a number of remedies that have always been firmly anchored in empirical medicine, but which was applied regularly only by the nature healer, have suddenly, in the light of new test methods, been shown to be effective medicines; thus, for example, onions and garlic are good for thrombotic processes and hyperglycaemia, carminatives for sphincter spasms in the gastrointestinal tract, and alcohol is an appetite-stimulating stomachic. This fact, the limited applicability of the information obtained from animal experiments, and the further fact that even test results obtained in human subjects cannot be applied on a world-wide basis, exhort us to take care not to subscribe to an all-too apodictic classification of therapeutic measures into effective and noneffective. A further point for consideration is that the administration even of what is only a supposed remedy, can trigger or promote healing simply on the strength of the action of the physician. Scientific thinking is an indispensible precondition of the physician's activity--to consider it as the beginning and end of all things medical, however, is simply to demonstrate a narrowness of outlook.

Antacids↗

PubMed1978

Reporting adverse reactions to herbal ingestants.

Explore the source record for details and available documents.

Aged↗

PubMed1978

Voluntary heart rate changes and the marihuana "high".

Investigated the interaction of psychological and physiological measures of the marihuana intoxicated state. The subjective measure of intoxication was the "How High" Scale, a rating of percentage of the S's usual "high." The objective measure was pulse rate, which has been found to be the most consistent physiological indicator of marihuana intoxication. By means of biofeedback techniques, Ss in the experimental group were taught to increase voluntarily pulse rate when intoxicated. A control group attended to feedback, but did not manipulate pulse rate. Group comparisons of the dependent measures demonstrated that while both groups experienced a similar subjective "high", the experimental group demonstrated a significantly higher pulse rate. This discrepancy between objective and subjective measures demonstrates the complexity of the intoxicated state.

Adult↗

PubMed1975

The analgesic properties of delta-9-tetrahydrocannabinol and codeine.

The administration of single oral doses of delta-9-tetrahydrocannabinol (THC) to patients with cancer pain demonstrated a mild analgesic effect. At a dose of 20 mg, however, THC induced side effects that would prohibit its therapeutic use including somnolence, dizziness, ataxia, and blurred vision. Alarming adverse reactions were also observed at this dose. THC, 10 mg, was well tolerated and, despite its sedative effect, may analgesic potential.

Analgesics↗

PubMed1976

Effects of marijuana extract and tetrahydrocannabinol on electroencephalographic sleep patterns.

Marijuana extract, given in daily doses containing 70 to 210 mg delta-9-tetrahydrocannabinol (THC), induced effects on sleep that were virtually identical to those produced by the same doses of relatively pure (96%) THC. Both drugs reduced eye movements density with some tolerance developing to this effect. Stage 4 tendend to increase with drug administration. Abrupt withdrawal led to extremely high densities of eye movement, increased rapid eye movement (REM) durations, and a sharp but transient fall in stage 4 to baseline levels. These effects may be useful in the elucidation of the pharmacology of sleep. The effects on sleep of THC administration (but not withdrawal) closely resemble those induced by lithium. For this reason, we suggest further studies of THC in affective disorders. Evidence available thus far suggests that THC produces dysphoric symptoms in unipolar but not in bipolar depressed patients; these differences in response may prove of diagnostic value. An adequate therapeutic trial of THC in bipolar depressed patients has not yet been carried out.

Administration, Oral↗

PubMed1976

Breast cancer and use of rauwolfia and other antihypertensive agents in hypertensive patients: a nationwide case-control study in Finland.

Two nationwide registers, the Finnish Cancer Registry and a register of persons entitled to free drugs for hypertension, were linked in a case-control study of the association of breast cancer and use of rauwolfia. Cases were all hypertensive patients in whom breast cancer was diagnosed in 1973. To test the association specifically with rauwolfia, controls were hypertensive women matched with the cases for age and geographic area and approximately matched for duration of treatment for hypertension. There were 109 case-control pairs. Use of any physician-prescribed drugs during the year prior to diagnosis of breast cancer was ascertained from original prescriptions. In the first set of analyses the patients were classified according to the drug used during most days of the year ("main antihypertensive agent"). In the second set a person qualified as a user of the respective drug regardless of the amount taken. The relative risks in the use of rauwolfia, methyldopa, another synthetic antihypertensive or a diuretic as main antihypertensive agent all ranged between 0.90 and 1.11. The results based on use of a drug in any amount were similar. Next, pairs in which duration of treatment for hypertension was different for cases and controls were excluded. The relative risk associated with use of rauwolfia as main antihypertensive agent then increased from 1.00 to 1.30 and the risk associated with use of any amount of rauwolfia from 1.16 to 2.14. Simultaneously, the relative risk in the use of digitalis was raised from 1.33 to 2.67 and of nitroglycerin from 1.00 to 1.71. Cases also used more types of antihypertensive agents simultaneously than controls. There was no association between rauwolfia-use and breast cancer in analyses limited to pairs in which neither case nor control used digitalis. Thus, there was not a consistent drug-specific association between rauwolfia-use and breast cancer in hypertensive patients. An underlying association of hypertension, heart disease or its treatment (digitalis) and breast cancer may have confounded some of the results of this and earlier studies. In conclusion, it is unlikely that use of rauwolfia increases the risk of breast cancer.

Adult↗