PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Polyarteritis Nodosa”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources

Ischemic pseudomembranous colitis with perforation due to polyarteritis nodosa.

Polyarteritis nodosa is a multisystem disease that involves the gastrointestinal tract in more than 50% of patients at some time during its course. Clinically apparent ischemic disease of the small bowel is the frequent site of involvement. The colon is less commonly involved, particularly as the initial presentation. We present a patient with polyarteritis nodosa noteworthy for prolonged nonbloody diarrhea, ischemic colitis with perforation, and pseudomembrane formation who had histological documentation of polyarteritis nodosa.

Colon↗

Duodenal necrosis as the presenting manifestation of polyarteritis nodosa.

Polyarteritis nodosa involves necrotising vasculitis of small and medium-sized arteries. Multiple organ systems are involved. A non-specific and slow course of disease is common. Gastrointestinal involvement is characterised by abdominal pain, nausea and vomiting. Bowel infarction and perforation, cholecystitis and hepatic infarction are well known complications. However, bowel infarction as the presenting symptom of the disease is rare. The case of a 20-year-old male with necrosis of the duodenum heralding polyarteritis nodosa is reported. The patient made a slow recovery after extensive abdominal surgery and a stormy course. The postoperative management and treatment of polyarteritis nodosa are discussed. A high index of suspicion and prompt multidisciplinary approach are needed in order to improve survival in these rare but potentially fatal conditions.

Adult↗

Polyarteritis nodosa.

Polyarteritis nodosa is one of the earliest forms of systemic vasculitis described. It is characterized by segmental necrotizing arterial lesions affecting medium-sized and small-sized arteries. Active necrotizing lesions are frequently associated with chronic reparative lesions. Current convention would exclude patients with necrotizing glomerular lesions from this category. An aneurysm may form when the arterial wall is sufficiently weakened by the necrotizing process. Any organ may be affected; however, pulmonary involvement is very uncommon. Significant potential exists for end organ injury resulting from ischemia, infarcts, and hemorrhage. A variety of other primary systemic vasculitidies, secondary forms, such as connective tissue disease associated, and organ limited forms, have been identified that may exhibit similar arterial lesions including aneurysm formation. Establishing a definitive diagnosis of polyarteritis nodosa is therefore challenging, and mandates dialogue between the pathologist and the clinician primed with pertinent clinical and laboratory data. Fortunately, with early diagnosis and aggressive treatment with cytotoxic agents, the prognosis of polyarteritis nodosa has substantially improved.

Arteries↗

Isolated ovarian polyarteritis nodosa.

Polyarteritis nodosa is a rare disorder and a form of systemic vasculitis. A 48 year-old female was admitted to the hospital because menorrhagia and pelvic pain in February 1993. The patient underwent exploratory laparotomy resulting in a total hysterectomy and bilateral salpingo-oophorectomy for myoma of uterus and a right adnexal cystic mass. Histopathologic examination revealed left ovarian periarteritis nodosa. Further investigation and 9 months follow-up failed to show any systemic involvement. To our knowledge the isolated ovarian polyarteritis nodosa is the first case in the literature.

Arteries↗

Care provided by a nurse managed center: polyarteritis nodosa.

Polyarteritis nodosa is a form of necrotizing vasculitis involving small and medium size arteries. Nursing care provided by baccalaureate nursing students in a nurse-managed center at San Jose State University's (CA) School of Nursing focuses on monitoring symptoms, preventing complications, and supporting patients and families affected by polyarteritis nodosa.

Aged↗

[Spontaneous perirenal hemorrhage in patients with polyarteritis nodosa].

Polyarteritis nodosa is a necrotising vasculitis of small and medium-sized arteries. All coats of these vessels are involved easily resulting in aneurysm formations. It is an immunologic disease owing to immune complexes deposits. Kidney affection is over 80%. Polyarteritis nodosa may be complicated by perirenal hematoma, hemobilia, intrahepatic hemorrhage, epidural hematoma. Spontaneous perirenal hematoma can be the initial manifestation of this disease. Abdominal ultrasonography can provide a quick diagnosis of complicating disease and embolization by interventional radiology may be considered a therapeutic alternative to surgery.

Diagnosis, Differential↗

Multiple spontaneous visceral hematomas revealing polyarteritis nodosa.

Polyarteritis nodosa is a rare life-threatening disease characterized by necrotizing vasculitis of small and median arteries. We describe the exceptional case of a 28-year-old man with successive spontaneous visceral hematomas of the kidney, bladder, and liver. Arteriography was performed for a recent spontaneous hepatic hematoma and a microaneurysm was detected, allowing the diagnosis of polyarteritis nodosa and prescription of appropriate treatment.

Adult↗

Polyarteritis nodosa.

Polyarteritis nodosa is a systemic necrotizing vasculitis of small and medium-sized arteries affecting multiple organ systems. Typical findings are illustrated.

Foot↗

Urologic manifestations of polyarteritis nodosa.

Polyarteritis nodosa is an unusual condition that infrequently presents with signs and symptoms essentially confined to the urinary system. Such a case necessitating bilateral nephrectomy owing to hemorrhage is described. The pathologic findings, pathophysiology and etiology of the condition as well as treatment by renal transplatation are discussed.

Adult↗

Extracranial head and neck circulation aneurysms in a case of polyarteritis nodosa.

Polyarteritis nodosa (PAN) is a rare systemic necrotising medium vessel vasculitis. The hallmark of this condition is aneurysms which are seen in visceral arteries. Aneurysms of extracranial neck and head vessels are rare. We describe a case of PAN who had such aneurysms together with characteristic aneurysms in the mesenteric circulation.

Adult↗

Spontaneous perirenal hematoma: a complication of polyarteritis nodosa.

Polyarteritis nodosa is a rare cause of perirenal hematoma owing to rupture of 1 of the aneurysms. Eleven cases have been reported previously in the English literature, including 5 with a preoperative angiographic diagnosis. Our case, which was diagnosed angiographically before a successful conservative operation, is the first report of a patient who survived 3 years. The pathology is discussed.

Adult↗

[Polyarteritis nodosa].

Polyarteritis nodosa (PAN) is the systemic necrotizing vasculitis on small and median muscular vessels. Recent studies reveal that PAN consists of classical PAN and microscopic polyangitis (MPA). MPO-ANCA, which is one of anti-neutrophil cytoplasmic antibody (ANCA), is involved in the pathogenesis of MPA. In future, by the progress of research of ANCA, the definition or criteria of systemic vasculitis including PAN or MPA will be changed.

Antibodies, Antineutrophil Cytoplasmic↗

Stroke-induced cardiovascular changes: a rare cause of death from polyarteritis nodosa.

Polyarteritis nodosa (PAN) is an uncommon but well documented cause of subarachnoid haemorrhage (SAH). We report a case of SAH in a patient with PAN causing death indirectly from the effects of resultant cardiovascular changes upon other manifestations of PAN. Clinicians should be aware of the systemic effects of SAH in patients with known vasculitides.

Aortic Rupture↗

Hemobilia as presenting manifestation of polyarteritis nodosa.

Polyarteritis nodosa (PAN) is a multisystem necrotizing inflammatory vasculitis of medium-sized muscular arteries. Hepatobiliary complications secondary to thrombosis or aneurysm formation in PAN are rare and are associated with poor outcome. We describe an 18-year-old man with PAN who presented with hemobilia secondary to rupture of a hepatic artery aneurysm, which was successfully managed with coil embolization followed by immunosuppressive therapy.

Adolescent↗

Ulcerative necrosis of the glans penis resulting from polyarteritis nodosa.

Polyarteritis nodosa (PAN) may be systemic or isolated in distribution and may involve virtually any organ or tissue in the body. We report an unusual case of PAN with the clinical features of both penile and renal involvement in a 21-year-old man diagnosed incidentally by pathologic examination of the nephrectomized left kidney. Systemic and surgical therapeutic procedures were applied and his symptoms resolved within 6 weeks. Penile ulceration is a rare but serious manifestation of PAN that needs prompt and aggressive treatment.

Adult↗

Diagnostic value of renal arteriography in polyarteritis nodosa.

Polyarteritis Nodosa (PAN) is a rare disease in childhood. No single pattern of clinical presentation characterizes this disease, but abdominal pain, central or peripheral nervous system disease, arthritis, myalgia and skin lesions occur at some time during the course of the illness. In this case a 16-year-old boy who presented with abdominal pain, elevated sedimentation rate associated with hypertension, and a high level of renin, all of which were detected during his hospitalization, suggested the diagnosis of PAN, and renal angiography was performed. Characteristic renal aneurysms were visualized and the diagnosis was confirmed.

Adolescent↗

Acute pancreatitis with pseudocyst formation in a patient with polyarteritis nodosa.

Polyarteritis nodosa (PAN) is a term that includes patients with necrotizing inflammation of medium sized arteries, and excludes those with microscopic vessel involvement. Its manifestations are protean and include constitutional symptoms such as fever, malaise, weight loss, myalgia, peripheral neuropathy, rash, and gut and renal involvement. Although gastrointestinal manifestations have been noted in up to a third of patients with PAN, clinical presentation with pancreatic involvement has been reported only rarely. We describe a patient with PAN who developed acute pancreatitis with pseudocyst formation as well as infarcts in the spleen and liver.

Acute Disease↗