Urban health disorders, spatial analysis, and the economics of health facility location.
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Epidemiologic studies of Creutzfeldt-Jakob disease (CJD) in countries throughout the world have consistently shown higher urban than national disease frequencies, but this finding has usually been ascribed to case-finding artefact. A detailed analysis has now been completed of annual mortality rates of CJD in France, based on a systematic study of 255 consecutive cases dying during the period 1968-1980, of whom 85 resided in the paris metropolitan area. In the country as a whole, the frequency of CJD increased from rural, through urban, to the Paris region; and in the Paris region, the frequency increased from the lowest to the highest density areas. The magnitude of this positive correlation between population density and the frequency of CJD is not explained by differences in age distribution of the various population groups, and suggests a role for random inter-human spread, either direct or indirect, in natural disease transmission.
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The distrubution of the reciprocal of von Neumann's ratio is considered under the random walk model, x(t+1) rwis;d xt + et, and it is shown how this quantity can be used to test for density dependence in animal populations. Another test is described which is robust under superimposed errors of measurement. The methods are used to analyze data on Canadian fur-bearing mammals.
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An estimate of the numbers of adults of the predacious mosquito Toxorhynchites brevipalpis was made in a 1-ha biotope in Dar es Salaam, Tanzania, where the population of its larval prey Aedes aegypti was high, by means of the mark-release-recapture method. Two months after the end of the rainy season, the number of adults was estimated to be 3 500-about 6 times the number of adult A. aegypti in the biotope.
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