[Baron de Lenval Institute of Child Hygiene. History, objectives, organization ond progress report. III. Progress report].
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Ambulatory Care Facilities↗
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Results for “Progress Report”
Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.
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Advanced detection of viral nucleic acids in the central nervous system: a progress report.
A progress report. We have helped to standardize an advanced in situ hybridization technology to detect viral nucleic sequences in formalin fixed paraffin embedded brain tissue with high sensitivity and specificity as well as good preservation of cytomorphology. It is our belief that if the inflammation in the multiple sclerosis central nervous system is associated with persistent virus this technique should reveal it. Technical reasons are given why we are continuing to search for measles virus in multiple sclerosis brain tissue.
Base Sequence↗
Diagnostic markers in human neurooncology. A progress report.
In this progress report, some of the most commonly used antibodies are discussed in regard to their immunohistochemical application to human neurooncology. The importance of determining the spectrum of antibody immunoreactivity in a wide panel of normal, reactive, and neoplastic tissues is stressed. in atypical and aberrant cases, immunopositivity needs to be interpreted with caution and in the context of all other available data. The demonstration of a well-characterized, cell type-specific marker in a tumor reflects not so much its cytogenesis as its differentiation potential and its capacity for metaplasia. The relation of an abnormal or aberrant expression of antigenic determinants to the process of neoplasia raises a number of intriguing questions to which research in the next few years will likely provide answers.
Antigens, Differentiation↗
Preventive cardiology: a progress report.
The progress to the current era of preventive cardiology covers a period of more than 40 years, beginning with epidemiological studies on coronary heart disease and other forms of atherosclerotic disease and related factors and progressing through prevention trials and community demonstration projects to the actual implementation of preventive measures by combined population and high-risk strategies. The scientists of the United States have played a leading role in the data collection which forms the scientific basis for preventive cardiology and the fruitful collaboration in the United States between the scientists and governmental, as well as nongovernmental, organizations in the implementation of preventive cardiology has served as a good example for other countries. The Section on Epidemiology and Prevention of the International Society and Federation of Cardiology and the Cardiovascular Diseases Unit of the World Health Organization, working in close liaison, have had key roles in the worldwide promotion of preventive cardiology. The rapid progress in preventive cardiology during the past 4 years, since the 1st International Conference of Preventive Cardiology, has been dominated by a "snowballing" movement toward more intensive application of cholesterol-lowering measures at both the population and the individual level. Promising progress has also been made in the field of nonpharmacological control of elevated blood pressure.
Adult↗
Should it be parietal cell vagotomy or selective vagotomy-antrectomy for treatment of duodenal ulcer? A progress report.
This is a progress report of a prospective, randomized study involving 200 consecutive patients treated electively with either parietal cell vagotomy (PCV) or selective vagotomy and antrectomy (SV-A). Both groups comprised patients with pyloric, prepyloric, or duodenal ulcers. There was no operative mortality in either group. Patients were examined at 2, 6, 12 months, and every 12 months thereafter for 8-10 years. The two operations produced no statistical difference in the frequency of diarrhea. Dumping (p less than 0.0005) and weight loss (p less than 0.0005-p less than 0.05) were statistically less after PCV than after SV-A. There were two recurrent ulcers (2.2%) after SV-A. One was treated successfully by medical therapy and one patient suspected of having gastrinoma had total vagotomy. Nine patients had recurrent ulcers in the PCV group for an accumulated recurrence rate of 10.1% at 10 years by life-table analysis. There was a significant difference (p less than 0.033) between the curves for recurrent ulcers in the two groups of patients. The recurrent ulcer rate after PCV was 21% for patients with pyloric and prepyloric ulcers and 6% for patients with duodenal ulcer. There was no significant difference between the recurrent ulcer rate for PCV and SV-A if the patients with pyloric and prepyloric ulcers were withdrawn from the study. Of the nine patients with recurrent ulcers in the PCV group, three had an inadequate vagotomy and four had a pyloric or prepyloric ulcer before operation. Three patients were successfully treated with antrectomy. Five patients were treated successfully by medical therapy and remained healed for long periods without recurrence. One patient had five recurrences. He declined operation and remained free of symptoms for 3 years after his last recurrence. Poor gastric emptying necessitated gastroenterostomy in five patients in the SV-A group and in one patient in the PCV group. Patients' clinical results were evaluated according to a simple Visick grading scale. A significantly (p less than 0.0005) greater number of patients were in Visick I category after PCV than after SV-A. The clinical results obtained with PCV make this the operation of choice for the elective surgical treatment of duodenal ulcers even though the results obtained with SV-A were good.
Adult↗
Effects of noinionizing radiation on the central nervous system, behavior, and blood: a progress report.
This paper presents a progress report on the U. S. research which has been designated as collaborative research with the Soviet Union to study the biological effects of nonionizing radiation on the central nervous system, behavior, and blood. Results of investigations to study the effects of microwaves on isolated nerves, synaptic function, transmission of neural impulses, electroencephalographic recordings, behavior, and on chemical, cytochemical and immunological properties of the blood are presented. Specifically, the effects of microwave exposure on chick brain and cat spinal cords, on EEG patterns of rats, on behavioral of neonatal rats exposed during development, on behavior of adult rats, on behavior of rhesus monkeys and on the pathology, hematology, and immunology of rabbits will be reported in a summary format. Much of the information is new and has not been published previously.
Action Potentials↗
Effects of intraoperative progress reports on anxiety of elective surgical patients' family members.
The purpose of this experimental study was to examine the effects of intraoperative progress reports on family members' state anxiety level (STAI S-Anxiety), mean arterial pressure (MAP), and heart rate during elective surgical procedures. Family members of randomly selected surgical patients were eligible to participate. Control group family members (n = 50) received usual care. Family members in the experimental group (n = 50) received a 5- to 10-minute progress report protocol about halfway through a surgical procedure. Families' STAI S-Anxiety scores, MAP, and heart rates were compared between the control and experimental groups using multivariate analysis of variance (MANOVA). Family members in the experimental group reported lower STAI S-Anxiety scores (p < .001), and had significantly lower MAP and heart rates than did the control group (p < .001). Progress reports appear to be a beneficial nursing intervention for reducing anxiety in family members during the intraoperative period.
Adolescent↗
Progress report on the anorectic effects of dexfenfluramine, fluoxetine and sertraline.
This progress report on the anorectic effect of serotoninergic indirect antagonists compares the action of D-fenfluramine, fluoxetine and sertraline and their N-dealkylated metabolites. Brain levels of drugs and their metabolites were measured after equi-active anorectic doses. Fluoxetine and sertraline inhibit 5-HT uptake in vitro with a potency which is at least one order of magnitude higher than for D-fenfluramine while all three drugs release 5-HT from synaptosomes and the active concentrations are closer to the brain concentrations reached after anorectic doses. However, a number of differences have been observed between D-fenfluramine and fluoxetine regarding the mechanisms of 5-HT release. Furthermore fluoxetine affected storage of 5-HT in vesicles much more than D-fenfluramine did. The anorectic effect induced by fluoxetine was not antagonized by antiserotoninergic drugs. No evidence of an involvement of CCK in the anorectic effect of D-fenfluramine was found when food intake was determined in rats previously submitted to food deprivation.
1-Naphthylamine↗
Use of National Health Service operating theatres in England. A progress report.
Following very shortly after the Bevan Report the National Audit Office has published a progress report on the utilisation of operating theatres in England. The report revisits Bevan in a number of areas, which emphasises the importance placed on the recommendations made in that report.
England↗
The concept of mainstream medicine for all Californians. Fifth progress report of Committee on Role of Medicine in Society. 3.
This Fifth Progress Report is being printed in three parts in California Medicine. Following the appearance of Part III the report will be bound in a pamphlet which may be ordered at $1 a copy from 693 Sutter Publications, Inc., 693 Sutter Street, San Francisco, California 94102.
Bibliographies as Topic↗
Second annual progress report on introduction and use of investigational anticancer agents in Australia, 1984-1985. Anticancer Subcommittee of the Australian Drug Evaluation Committee.
Since the publication of its first report, the Anticancer Subcommittee of the Australian Drug Evaluation Committee (ADEC) has provided advice to ADEC and to the Commonwealth Department of Health on investigational anticancer agents in all stages of development. This second report outlines the progress in 1984-1985.
Antineoplastic Agents↗
Bloom's syndrome. VII. Progress report for 1978.
The Bloom's Syndrome Registry was published in this journal in 1977. Now, in the first in a series of progress reports, recent accessions to the Registry are recorded, new instances of neoplasia are listed, and recent clinical observations and experimental results of general interest are cited.
Abnormalities, Multiple↗
Meeting the 1990 hypertension objectives for the nation--a progress report.
The National High Blood Pressure Education Program (NHBPEP) effort got underway in 1972 following hypertension research findings and continues to be influenced and, when necessary, redirected, by further findings. Its coordinating committee is composed of representatives from 32 national organizations, and the program itself includes several Federal agencies, all State health departments, and more than 2,000 community-based programs. The goals of NHBPEP and the 1990 prevention objectives for the nation center around the same basic theme: high blood pressure is a serious condition leading to major diseases and premature death. It can be easily detected and effectively brought under control. In the summer of 1984, Admire and co-workers provided a general review and status report of the 1990 Hypertension Objectives and the progress made in meeting those objectives. In the remarkably short period of time since that review, there is even more progress to report. There is good evidence of progress in preventing disease and premature death from hypertension, in bringing hypertension under long term control, and in giving Americans a better understanding of the consequences of uncontrolled high blood pressure. There is also evidence in the fact that while visits to physicians generally have increased only slightly, hypertension visits have increased more markedly. And there is evidence that stroke mortality continues to decline in an almost linear fashion.
Adult↗
Progress report from the International Bone Marrow Transplant Registry.
The International Bone Marrow Transplant Registry receives and analyses detailed information contributed by more than 200 transplant teams worldwide. This collaborative research program has grown rapidly; there are now more than 15,000 cases in the database. This progress report summarizes the current status of bone marrow transplantation, the results of recent investigations and studies planned for the coming year.
Anemia, Aplastic↗
Diabetogenic activity of the anterior pituitary (a progress report).
The exact nature of the diabetogenic activity of the anterior pituitary gland remains a mystery. While growth hormone (GH) fractions clearly can produce a diabetogenic effect, there is increasing evidence that GH itself does not exert this effect. Several new theories that purport to explain the nature of diabetogenic activity are discussed. The current evidence supports the view that the activity is the result of a GH fragment or some other closely related protein such as the one ("diabetogenic protein") first described by LOUIS and CONN. A progress report of the research on this new "diabetogenic protein" is given.
Adipose Tissue↗
Porcine enteroviruses: a serologic comparison of thirty-eight Pennsylvania isolates with other reported North American strains, Teschen, Talfan, and T80 serums--a progress report.
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Animals↗
Progressive familial heart block. Part II. Clinical and ECG confirmation of progression--report on 4 cases.
Two types of progressive familial heart block controlled by a single gene have been described; 4 cases show that type I is progressive and that the pathogenesis is still unknown.
Adult↗
Development of antiretroviral therapy for the acquired immunodeficiency syndrome and related disorders. A progress report.
We review the rationale for, and progress in, the development of antiviral therapy for the acquired immunodeficiency syndrome (AIDS). A consideration of the replicative cycle of the human immunodeficiency virus (HIV) can lead to the identification of several steps that represent potential targets for antiretroviral therapy, and several substances that can inhibit the replication of HIV in vitro have already been identified. The 2',3'-dideoxynucleosides are a class of nucleoside analogues in which the 3'-hydroxy group is modified so that it cannot form phosphodiester linkages for nucleic acid chains. Some are potent in vitro inhibitors of HIV replication, possibly acting as chain terminators of viral DNA during reverse transcription. One of these dideoxynucleoside analogues, 3'-azido-2',3'-dideoxythymidine (AZT), has now been administered for up to 18 months to patients with AIDS. The drug has been shown to improve immunologic function, to reverse, at least partially, HIV-induced neurologic dysfunction in some patients, and to improve certain other clinical abnormalities associated with AIDS. The principal toxic effect associated with AZT is dose-dependent suppression of bone marrow, resulting particularly in anemia and leukopenia; however, most patients in whom this toxic effect occurs can subsequently tolerate a lower dose of the drug. The demonstration that AZT can be beneficial in patients with AIDS has removed some of the uncertainty about the rationale for an antiretroviral intervention in HIV infection.
Acquired Immunodeficiency Syndrome↗