PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Pulmonary Heart Disease”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources
PubMed1977

Digitalis in pulmonary heart disease (cor pulmonale).

The use of digitalis in pulmonary heart disease has been a topic of great interest for a number of years. The physician's decision to use or not to use digitalis in pulmonary disease has often been an emotional rather than a reasoned one. The diagnostic difficulties from a clinical point of view in separation of pulmonary from cardiac symptoms and findings have also been confusing. The fact that small doses of digitalis may have an inotropic effect on the cardiac muscle has been a difficult concept for many physicians to adopt. On the other hand, the larger doses of digitalis that are often necessary to control the ventricular response in supraventricular arrhythmias sometimes gives rise to confusion. We shall attempt to review the subject in detail and examine indications, contraindications, toxicity, dosage, assessment of benefit, and role of digitalis serum levels in patient management.

Arrhythmias, Cardiac↗
PubMed1979

Pulmonary heart disease: pathophysiology, diagnostic signs, and therapy.

The anatomy and physiology of the pulmonary vasculature has been described with emphasis on several types of pulmonary hypertension and their pathophysiology. Treatment of pulmonary hypertension may be successful, especially when disease is related to emboli which respond to anticoagulant therapy. Relief of mitral valve obstruction is usually beneficial. Patients with abnormalities of blood PO2 and pH (especially in chronic obstructive lung disease) may be spared increased pulmonary pressure or may reverse existing pulmonary hypertension by giving up smoking, learning more efficient ventilatory methods, and when indicated, using supplemental oxygen, bronchodilators, digitalis, diuretics, or a combination of these.

Electrocardiography↗
PubMed1975

Cor pulmonale (pulmonary heart disease): present-day status.

In reviewing the present-day status of cor pulmonale, it is clear that considerable progress has been made in almost all instances of the disease. It is clearly a preventable form of heart disease in most cases and it is treatable and curable in its most common form, i. e., in COPD. One must agree with Petty, that today we have effective means of caring for the majority of respiratory cripples. Therapy for lung disease now appears even to have reduced the expected rate of pulmonary function deterioration in some patients. Surely with improved gas exchange and early detection of respiratory insufficiency the outlook for patients with respiratory diseases leading to cor pulmonale is better today than it was 30 years ago.

Adult↗
PubMed1975

[Early electrocardiographic signs of chronic pulmonary heart disease].

Early electrocardiographic diagnosis of chronic cor pulmonale was attempted in the study of 312 patients with chronic pneumonia and in 251 normal individuals. In comparing the mean values of several ECG indices in chronic pneumonia, Stage 1, some signs with significant differences were revealed (amplitude of the PaVF wave, ratio of the hight of the PII and TII Waves, are of the PII wave). These signs appeared to be most informative. The following groups were singled out: 38 patients with chronic pneumonia, Stages 1 and 2 with signs of bronchospasm, and 53 persons with the same stages of the disease, but free of bronchial patency disorders. The ECG of these groups of patients was evaluated by means of the tables of electrocardiographic diagnosis of right atrial hypertrophy. The signs of overloading of the right atrium were revealed with statistical significance more often in patients with bronchospasm. The possibility of using this table for revealing early electrocardiographic signs of chronic cor pulmonale was also established; these signs include the amplitude of the PII wave greater than 2 mm and PaVF 1.5 mm, ratio of the hight of the PII and TII waves less than 0.75, the are of the PII wave greater than 0.09.

Adult↗
PubMed1979

Comparison of the size of the arterial vascular bed to the right ventricular mass in patients with chronic obstructive pulmonary disease.

Hearts from patients dying with severe chronic obstructive pulmonary disease were examined for right ventricular mass and coronary arterial vascular bed size. Normal hearts obtained from patients dying of other causes were also examined for comparison. The relationship between the size of the vascular bed and ventricular mass was examined and a definite but low correlation was found. Severe obstructive coronary artery disease was excluded, and chronic hypoxemia did not alter the results. The arterial vascular bed supplying the right ventricle of male patients with severe chronic obstructive pulmonary disease appears to undergo a compensatory increase in size as the ventricular mass enlarges, but this is highly variable and incomplete.

Blood Gas Analysis↗
PubMed1977

[Misleading pulmonary emboliu].

The authors report 12 cases of pulmonary embolism with misleading signs and discuss the difficulty in diagnosis: 1) the frequency of incomplete forms; 2) lack of specificity of the clinical and paraclinical picture of pulmonary embolism which may simulate pulmonary or heart disease; 3) difficulties in interpretation of the signs of pulmonary embolism in cases of prior heart or pulmonary disease.

Aged↗
PubMed1977

Fibrin thrombosis in monocrotaline pyrrole-induced cor pulmonale in rats.

Investigations were carried out to determine the lung lesions responsible for the development of pulmonary heart disease, cor pulmonale, in rats treated with monocrotaline pyrrole or monocrotaline. Animals with right ventricular hypertrophy showed microscopic lung alterations consisting of alveolar edema; fibrin thrombi with partial to complete occlusion of arteries, arterioles, capillaries, and veins; connective tissue proliferation of alveolar septae; cellular hyperplasia of septae; and medial hypertrophy of arterioles. Due to the high incidence of fibrin thrombi in animals with right ventricular hypertrophy, we believe that formation of fibrin thrombi plays a decisive role in the development of chemically induced cor pulmonale.

Animals↗