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Results for “Raynaud Disease”

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At least 19 recordsLinked to original sources
PubMed1979

[The blood-flow in hands with Dupuytren's contracture and Raynaud disease: functional and morphological studies (author's transl)].

Concerning the question whether a correlation between the vasospasm and morphological changes in the neuro-myo-arterial glomerular (Hoyer-Grosser-Organ) exists also in Dupuytren disease, a series of 18 patients with Dupuytren and 5 patients with Raynaud disease were studied by finger venous occlusion plethysmography and finger tip biopsies. No typical histological changes were found in Dupuytren's Contracture, particularly none in the 13 cases (70%) which had a latent vasospasm and none in the 5 cases (30%) which had a normal plethysmogram, whereas in all the patients with Raynaud disease the typical morphological changes of wall, lumen and morphometric counts of the "Suquet-Hoyer" canals were found in correspondance to the abnormal plethysmogram. According to these results the vasospasm of Dupytren and Raynaud disease seems to be pathogenetically different.

Blood Circulation↗
PubMed1979

Biofeedback as therapy in Raynaud's disease.

The following dimensions of Raynaud's disease are reviewed: (a) etiological factors, particularly those of a psychological nature, (b) proposed biological mechanisms of vasospastic episodes, (c) efficacy of pharmaceutical and surgical interventions, and (d) use of biofeedback as therapy. Emotional stress appears to be wholly sufficient to induce vasopastic episodes in victims. Some authors further hypothesize that suppressed anger may be involved in the phenomenon. Vehicles proposed to account for the symptoms include local vascular pathology, sympathetic discharge, and biochemical phenomena. Sympathectomy does not produce permanent remission and vasodilator medications tend to have undesirable side effects even when successful. Documented success with feedback techniques is sparse but encouraging. Published outcome studies are often confounded by the use of additional treatment modes such as relaxation training and hypnosis. The study of Raynaud's disease has enormous potential for the understanding of psychosomatic illness in a holistic fashion. Stresses induce immediate physiological responses, and corrective conditioning is easily implemented and monitored.

Adult↗
PubMed1978

Reserpine treatment of Raynaud's disease.

Six patients with primary Raynaud's disease were investigated with magnification hand arteriography, measurement of finger systolic pressure and response to a newly devised local cooling test. They were treated with reserpine 0.5 mg injected into the brachial artery, and the clinical effects were followed by a scoring system and by the change in digital arterial tone during local cooling. The latter was registered as the change in systolic finger blood pressure measured indirectly by a finger-plethysmograph during stepwise decrease in finger temperature, until at a critical temperature complete closure of the digital arteries occurred. Shortly after injection the clinical condition improved, and closure of the digital arteries during local cooling was impeded. But within a week the cooling test showed a transient deterioration with closure of the digital arteries at the same or a somewhat higher temperature than before the reserpine injection. The clinical score followed this trend. According to animal experiments the shortlasting vascular effect of reserpine on primary Raynaud's disease might be due to depletion of the sympathetic nerve terminals for norepinephrine.

Adult↗
PubMed1978

Pathophysiology of capillary circulation: Raynaud's disease.

Despite the frequency of Raynaud's disease in cold climates, the etiology of the condition remains uncertain. This report reviews the literature since Raynaud's original description and Lewis and Pickering's addition to the concept, and several recent observations which add to our understanding of the disease are discussed. We investigated the effect of posture and a vasodilator drug on the digital capillary circulation; digital blood flow increases as the body moves from a recumbent, through a sitting, ti an upright position. Bradilan, a vasodilator drug, increases the circulation in the recumbent and sitting positions, but has no effect in standing patients, despite symptomatic relief.

Blood Circulation↗
PubMed1978

Plasmapheresis in Raynaud's disease.

Understanding of the pathogenesis, clinical course, and treatment of Raynaud's disease is confused and unsatisfactory, and no success in treatment can be promised. Five patients with severe Raynaud's disease, who had not responded to other forms of treatment, were treated by plasmapheresis, which produced a striking improvement. Ultrasonic velocimetry showed that segments of digital arteries which had been thought to be permanently occluded became patent and remained patent after plasmapheresis.

Adult↗
PubMed1978

Treatment of Raynaud's disease: evaluation of a behavioral approach.

Eight patients with Raynaud's disease were treated with a behavioral program which included skin temperature biofeedback, relaxation training and protocol individualization based on the investigators' psychological understanding of each patient. Three patients improved clinically, although only one learned self-control of skin temperature. Anxiety reduction, brought about by relaxation or changes in the program to suit individual needs, appeared to be an important aspect of the treatment program.

Adult↗
PubMed1979

[Functional diagnosis by directional doppler-ultrasound in patients with Raynaud's disease (author's transl)].

7 patients with primary and 3 patients with secondary Raynaud's disease were studied by directional Doppler-ultrasound. Flow curves were registered of radial and ulnar artery in rest and during reactive hyperemia following ischemia and muscle work before and under medical treatment. Flow at rest and after provocation was much less than in normal persons. Effect of treatment could be demonstrated, so that this method seems to be very helpful in followup studies of patients with Raynaud's disease.

Adult↗
PubMed1978

Behavioral treatment of Raynaud's disease.

In order to assess the efficacy of a behavioral intervention in the treatment of idiopathic Raynaud's disease, 30 female patients were trained to control their digital skin temperature using autogenic training or a combination of autogenic training and skin temperature feedback either in the laboratory or at home. All trained subjects demonstrated a significant ability to maintain digital skin temperature in the presence of a cold stress challenge and reported significant reductions in both frequency and intensity of vasospastic attacks. The addition of skin temperature feedback to autogenic training did not provide additional clinical benefit.

Adult↗
PubMed1979

[Misdiagnosis: Raynaud's disease].

Within a few hours a patient developed necrosis of two finger tips. A provisional diagnosis of Raynaud's disease was made and an arteriogram was performed. This showed considerable hypervascularisation of the affected fingers. After 48 hours, the typical clinical picture of an acute infection became evident. The differential diagnosis and pathogenesis are discussed.

Angiography↗
PubMed1978

Treatment of Raynaud's disease with temperature biofeedback.

A 40-year-old white woman who for 15 years had had Raynaud's disease--a vascular disorder characterized by poor blood circulation and coldness in the extremities--was treated with temperature biofeedback. In treatment sessions over a 13-month period she was provided with continuous, moment-to-moment information about the rise and fall of fingertip temperature. Gradually she was able to learn to raise her peripheral temperature and to gain some volitional control over a highly complex physiologic response.

Adult↗
PubMed1979

Pregnancy in a patient with Raynaud's disease.

We report a patient who, at the time of her third pregnancy at the age of 35, had had Raynaud's disease for 18 years. Her first pregnancy (during which she took Marcumar, an anticoagulant) ended in a miscarriage at three months gestation. The second pregnancy ended in fetal death due to placental insufficiency. The third pregnancy was also complicated by placental insufficiency which became evident during the second trimester. The patient was observed carefully and allowed to continue to 37 weeks gestation when a Caesarean section was done for late fetal heart rate decelerations during early labour of spontaneous onset. The baby had a low birth weight but developed normally. The placenta showed certain abnormalities which are described.

Adult↗