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At least 19 recordsLinked to original sources
PubMed1985

[Incidence of lipid changes in rhegmatogenous retinal detachment, retinal vein occlusion and primary chronic glaucoma].

Several studies suggest that vascular factors may play a role in the pathogenesis of rhegmatogenous retinal detachment, retinal vein occlusion and primary chronic glaucoma. We explored the lipoprotein abnormalities in three groups of 45 patients suffering from each of these diseases compared to three control groups. We did not find significant abnormalities of cholesterol, cholesterol lipoproteins, nor Apolipoprotein B. The only significant abnormality was the presence of a higher rate of hypertriglyceridemia in the retinal vein occlusion and primary chronic glaucoma groups in comparison with their control group. In these two affections, hypertriglyceridemia should be systematically researched and treated.

Apolipoproteins B↗
PubMed1992

Retinal detachment.

Retinal detachment is a separation of the neurosensory retina from the retinal pigment epithelium. Most retinal detachments are rhegmatogenous, and identification of risk factors and predisposing lesions are important aspects of patient management. Retinal detachment is relatively rare, but can pose a significant threat to vision if there is macular involvement. Prompt diagnosis combined with patient education and appropriate intervention often can avert irrevocable visual impairment. This paper presents an overview of the categories of retinal detachment, discusses the pathogenesis of the various types of detachment, and provides recommendations for primary care of patients with predisposing factors and high-risk characteristics.

Choroid↗
PubMed1987

Glial fibrillary acidic protein increases in Müller cells after retinal detachment.

Retinal detachment, separation of the neural retina from the retinal pigment epithelium (RPE), initiates a series of changes in the eye which result in loss of vision if the retina is not rapidly reattached to the RPE. Many of the complex effects of this separation on the cell biology of the retina have yet to be determined. We report here a change in the amount and location of a specific cytoskeletal protein, glial fibrillary acidic protein (GFAP), within Müller cells after retinal detachment. Cat neural retina and RPE were separated by injecting fluid into the extracellular space between the retina and RPE. Normal retinas and retinas detached for 30 days were fixed and embedded for conventional electron microscopy or immunocytochemistry, or homogenized and processed by SDS-PAGE for immunoblot analysis with anti-GFAP. In normal retinas and in attached retinal regions of eyes with retinal detachment, GFAP was detected only in the end feet of the Müller cells as 10 nm diameter filaments and as a diffuse component over the cytoplasm. By contrast, in regions where the retina was detached from the RPE, GFAP was localized throughout the Müller cells in both of these forms. Immunoblots revealed a significant increase in anti-GFAP labeling of a 51,000 MW band from the detached retina.

Animals↗
PubMed1975

Myopia-aphakia. I. Prevalence of retinal detachment.

Retinal detachment after cataract extraction occurred in nine out of 136 eyes with myopia of 6 or more dioptress (6-7 per cent), during a follow-up period of 1 1/2-9 1/2 years. Five of the nine detachments occurred within 3 months of cataract extraction. All patients with retinal detachment were under the age of 63 years. Relatively young patients with high myopia bear a special risk of developing retinal detachment after lens extraction. The possible reason for this is discussed.

Age Factors↗
PubMedDate not supplied

Subretinal nematode. An unusual etiology for uveitis and retinal detachment.

Retinal detachments are usually divided between rhegmatogenous and exudative. Many causes for exudative retinal detachments are described in the literature. Subretinal nematodes are a rare but well-known etiology for severe exudative retinal detachments and endophthalmitis. The case presented represents the first known infestation of human ocular tissue by the nematode Porrocaecum or Hexametra. Described are the presenting symptoms and medical and surgical management, including pars plana vitrectomy, retinotomy, and air-fluid exchange to salvage the eye.

Adult↗
PubMed1992

[Retinal detachment].

Retinal detachment can be successfully treated today in over 90% of patients. For a good functional prognosis early diagnosis and appropriate initial treatment remain crucial. Symptoms of incipient retinal detachment are those of acute posterior detachment of the vitreous body with "mouches volantes" and/or photopsia. At risk and thus to be examined urgently if such symptoms occur are patients with previous history of detachment, severe myopia, aphakia or pseudophakia. Prophylactic treatment of degenerative retinal lesions that can be interpreted as precursors of detachment is highly controversial and only indicated in patients with particular risk factors. Research in surgical treatment of retinal detachment focuses on improvement of functional result by improved instruments and standardized operative techniques.

Humans↗
PubMed1989

Changes in the expression of specific Müller cell proteins during long-term retinal detachment.

Retinal detachments were produced in domestic cats by injecting fluid between the retinal pigment epithelium and neural retina. Retinas were allowed to remain detached for 30 or 60 days at which time the animals were killed. Tissue areas from detached and attached retinal regions from the same eye were processed for correlative biochemical and structural analysis, i.e. SDS-PAGE and Western blots of tissue homogenates were correlated with tissue processed for postembedding immunoelectron microscopy. Antibodies to six proteins were used as probes. Glial fibrillary acidic protein in Müller cells has previously been shown to increase after retinal detachment; here we show that vimentin, another intermediate filament protein present in Müller cells, also increases after detachment. In contrast, cellular retinaldehyde binding protein, cellular retinol binding protein, glutamine synthetase, and carbonic anhydrase C--all normally found in Müller cells--decrease after detachment. The results of this study indicate that retinal Müller cells dramatically alter their expression of proteins in response to retinal detachment.

Animals↗
PubMed1986

The use of retinal tacks in the repair of complicated retinal detachments.

Retinal tacks that can be easily placed and removed allow precise intraocular control of retinal fixation in the repair of complicated retinal detachments. We used this technique in 41 consecutive cases of complicated retinal detachment. In 37 cases follow-up was six months or more. We achieved reattachment of the posterior pole, including the macula, in 22 patients after six months or more of follow-up. Postoperative visual acuities were 1/200 or better in 15 patients and 5/200 or better in six.

Humans↗
PubMed1977

Phacoemulsification and retinal detachment.

Retinal detachment is not eliminated nor decreased to a rare complication after PE. There were 94 eyes with retinal detachments after PE examined and the majority operated. The fundus view might be hampered and some areas of the retina obscured by this form of lens extraction. There are, however, some cases where the small incision and relative clarity of the media, soon after cataract surgery, offer an advantage.

Adolescent↗
PubMed1978

Phacoemulsification and retinal detachment.

Retinal detachment is not eliminated nor decreased to a rare complication after phacoemulsification. There were 94 eyes examined with retinal detachments after phacoemulsification and the majority were operated upon. The fundus view might be hampered and some areas of the retina obscured by this form of lens extraction. There are, however, some cases where the small incision and relative clarity of the media, soon after cataract surgery, offer an advantage.

Adolescent↗
PubMed1989

[Retinal detachment].

Retinal detachment is a rare but serious disease with potential socio-professional repercussions. Its prevention rests on information of medical practitioners and patients and on photocoagulation with argon laser. Nowadays, the curative treatment of retinal detachment is surgical. When applied at an early stage and correctly performed, it should normally give satisfactory functional results.

Humans↗
PubMed1988

Effects of laser wavelengths on experimental retinal detachments and retinal vessels.

We studied the effects of the yellow (577 nm), orange (595 nm) and red (630 nm) dye lasers, the argon blue-green (488, 514.5 nm) and green (514.5 nm) lasers, and the krypton red (647 nm) laser on experimentally produced serous and hemorrhagic retinal detachments and on retinal vessels in rabbits. Retinal detachments were created by either injecting balanced saline solution or partially hemolyzed blood under the retina. All laser wavelengths except the argon blue-green bypassed the sensory retina and produced no damage on either the sensory retina or the underlying retinal pigment epithelium with serous retinal detachment. Each laser wavelength, however, produced a specific effect on the detached retina with hemorrhagic fluid. Blue-green, green, yellow and orange wavelengths damaged the sensory retina more severely than the red wavelengths. Laser coagulation of the retinal vessels with the blue-green, green and orange wavelengths produced vasospasms.

Animals↗
PubMedDate not supplied

Retinal detachment and retinal holes in retinitis pigmentosa sine pigmento.

Retinal detachment and retinal holes in two family members with retinitis pigmentosa sine pigmento are reported. We believe these are the first such cases reported in the literature. We describe the presenting symptoms and management, including cryotherapy, scleral buckling procedure, and sulfur hexafluoride injection (SF6), resulting in stable visual acuity in one case and retinal reattachment and improved visual acuity in the other case.

Adult↗
PubMed1979

Rhegmatogenous retinal detachment with retinal telangiectasia.

A 34-year-old man with unilateral retinal telangiectasia developed a bullous retinal detachment. A horseshoe retinal tear was found at 12 o'clock. The detachment resolved with placement of an encircling scleral buckle. The prompt and permanent resolution of subretinal fluid supported our belief that this was a rhegmatogenous retinal detachment.

Adult↗
PubMed1985

Giant retinal tears, retinal detachment and retinitis pigmentosa.

A patient with retinitis pigmentosa and sensorineural deafness presented with bilateral giant retinal tears and a unilateral retinal detachment. The peripheral visual field loss could have been erroneously ascribed to the primary retinal dystrophy. A retinal detachment must be considered in patients with a sudden loss of visual acuity or field even if they have a primary retinal dystrophy.

Adolescent↗
PubMed1990

[Visual acuity and binocular vision following surgery of extreme retinal detachment].

Retinal surgery with implantation of silicone oil was performed in 33 patients presenting with idiopathic or traumatic proliferative vitreoretinopathy. Following removal of the oil patients were on average followed-up for 6 to 29 months (14 months). Sixteen patients had had buckling procedures prior to endosurgery. Improvement of vision up to 4 rows of optotypes was noted in 21 patients following silicone oil removal. Three cases showed a large, organic, central scotoma. Ten patients suffered from diplopia; 3 of whom were known to have had a preexisting strabismus. Suppression of the visual impression of the operated eye was seen in 4 cases. Eye muscle surgery was necessary in 4 cases. Sixteen patients demonstrated normal binocular vision as far as possible taking the visual acuity into account.

Adolescent↗
PubMed1985

Retinal detachment in retinitis pigmentosa.

Three cases of retinal detachment occurring in patients with retinitis pigmentosa are presented and three previously reported cases reviewed. All the detachments were rhegmatogenous. One patient had a horseshoe tear, one had oral bay tears, two had dialyses, one a giant tear and in one case the break was not specified. Three patients were high myopes. All the patients were young males. The five operable cases all responded satisfactorily to conventional surgery. Histologically apparent adhesions between retinal pigment epithelium and neuroretina have been described in advanced cases of retinitis pigmentosa in older patients and may not be present in younger patients with less advanced disease. Until these adhesions occur patients with retinitis pigmentosa may have no additional protection against retinal detachment.

Adolescent↗