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At least 19 recordsLinked to original sources
PubMed2026

The complete chloroplast genomes of Rhamnus arguta Maxim. and R. parvifolia Bunge (Rhamnaceae).

The genus Rhamnus L. (Rhamnaceae) has high medicinal, ecological, and ornamental value, but its infrageneric classification remains unclear. Here, we sequenced, assembled, and annotated the complete chloroplast genomes of Rhamnus arguta and R. parvifolia using Illumina sequencing. Both plastomes exhibit the typical quadripartite structure, with lengths of 160,566 bp and 161,243 bp, containing 128 and 129 genes, respectively. Phylogenetic analyses support the monophyly of Rhamnus and its close relationship with Frangula. This study provides genomic resources for further phylogenetic and comparative studies within Rhamnaceae.

Chloroplast genome↗
PubMed1994

Rhamnetin 3-p-coumaroylrhamninoside from Rhamnus petiolaris.

From the berries of Rhamnus petiolaris a new acylated flavonol glycoside was isolated and identified as rhamnetin 3-O-[3""-O-(p-coumaroyl)-alpha-L-rhamnopyranosyl(1-->3)- alpha-L-rhamnopyranosyl(1-->6)]-beta-D-galactopyranoside. Additionally, five known flavonol glycosides, rhamnetin, rhamnazin, quercetin and kaempferol 3-rhamninosides, and quercetin 3-rhamnoside were isolated.

Carbohydrate Sequence↗
PubMed1986

Hypotensive effect of Rhamnus lycioides extracts.

Intravenous administration of a lyophilized hot water extract and various organic solvent extracts of Rhamnus lycioides to normotensive anesthetized Wistar rats produced a lowering of systemic arterial blood pressure. Acute toxicity of the lyophilized extract was studied in mice by intraperitoneal injection. The phytochemical analyses revealed the presence of steroids-triterpenes, catechin tannins, flavonoids, sugars and resins.

Animals↗
PubMed1990

A hypotensive procyanidin-glycoside from Rhamnus lycioides ssp. lycioides.

A lyophilized hot water extract of the aerial parts of Rhamnus lycioides L. (Rhamnaceae) produced a lowering of systemic arterial blood pressure in normotensive anaesthetized Wistar rats. An activity-guided fractionation of the methanolic extract led to the isolation of a tetrameric procyanidin-glycoside which produced a clear dose-dependent hypotensive response (1.5-6 mg/kg i.v.). This principle was characterized using acid hydrolysis, thiolytic degradation and spectroscopic methods. It consisted of four flavanol units with a 2,3-cis configuration and with a O-beta-d-glucosylpyranoside function on the epicatechin terminal unit. The interflavan linkage was (4-8).

Animals↗
PubMed1991

Flavonol and anthraquinone glycosides from Rhamnus formosana.

Two new flavonol triglycosides, and a new anthraquinone glycoside, have been isolated from the roots of Rhamnus formosana. These compounds have been characterized as rhamnazin 3-O-[alpha-L-rhamopyranosyl(1----4)-alpha-L-rhamnopyranosyl(1----6 )]-beta-D-galactopyranoside (rhamnazin 3-isorhamninoside), rhamnocitrin 3-O-isorhamninoside and 1,6,8-trihydroxy-3-methylanthraquinone 1-O-rhamnosyl(1----2)glucoside, respectively.

Anthraquinones↗
PubMed1989

[Studies on isolation, purification and structure of NLC-A of Rhamnus heterophyllus].

A water-soluble glucan, NLC-A, from the roots of Rhamnus heterophyllus Olive was obtained as a homogeneous component as determined by HPLC. NLC-A was shown to compose of D-glucose, and its MW was estimated to be 1.2 x 10(4). Methylation analysis, peroxidation analysis, Smith degradation and reaction with I2-KI showed that NLC-A is a (1----4) linked alpha-D-glucan to which are attached glucosyl side chains at 0-6 of the glucosyl residues of the main chain.

Chemical Phenomena↗
PubMed1993

Frangulin B, an antagonist of collagen-induced platelet aggregation and adhesion, isolated from Rhamnus formosana.

Emodin and its glycoside frangulin B were isolated from the plant Rhamnus formosana. Emodin inhibited the aggregation of rabbit platelets induced by arachidonic acid and collagen, without affecting that by ADP or PAF, while emodin acetate had no any antiplatelet effect. Frangulin B inhibited selectively and concentration-dependently collagen-induced aggregation and ATP release in rabbit platelets, without affecting those induced by arachidonic acid, ADP, PAF and thrombin. Frangulin B also inhibited the platelet aggregation induced by trimucytin which was reported to be a collagen receptor agonist isolated from Trimeresurus muscrosquamatus snake venom. The aggregability of platelets inhibited by frangulin B could be recovered after washing the platelets. Frangulin B also selectively suppressed the thromboxane B2 formation caused by collagen, but not those by arachidonic acid and thrombin. Similarly, the formation of inositol phosphate caused by collagen was also suppressed by frangulin B, while that of PAF or thrombin was not affected. In the presence of PGE1, frangulin B also decreased Mg(2+)-dependent platelet adhesion to collagen. It is concluded that frangulin B may be an antagonist of collagen receptor in platelet membrane.

Amino Acid Sequence↗
PubMed1991

Antihypertensive action of a procyanidin glycoside from Rhamnus lycioides.

The antihypertensive action of a procyanidin glycoside isolated from Rhamnus lycioides aerial parts was studied in spontaneously and renal hypertensive rats. This compound, like 20 micrograms/kg i.v. of captopril, produced a very clear in vivo inhibition of angiotensin I converting enzyme when given at a dose of 3 mg/kg i.v.

Angiotensin-Converting Enzyme Inhibitors↗
PubMed1993

Studies on the constituents of Turkish plants. I. Flavonol triglycosides from the fruit of Rhamnus thymifolius.

Two new flavonol glycosides have been isolated from the fruit of Turkish Rhamnus thymifolius (Rhamnaceae) and their structures were elucidated as kaempferol-3-O-alpha-L-rhamnopyranosyl(1-->3)-(4-O-acetyl)-O-alpha-L- rhamnopyranosyl-(1-->6)-O-beta-D-galactopyranoside and kaempferol-4'-O-alpha-L-rhamnopyranosyl(1-->3)-O-alpha-L-rhamnopyranosyl (1-->6)-O-beta-D-galactopyranoside based on spectral and chemical evidence.

Carbohydrate Sequence↗
PubMedDate not supplied

Tumor inhibitors. 114. Aloe emodin: antileukemic principle isolated from Rhamnus frangula L.

A systematic fractionation of an ethanol-water (1:1) extract of the seeds of Rhamnus frangula L., guided by assays for tumore-inhibitory activity, led to the isolation of aloe emodin (1). This compound was found to show significant antileukemic activity against the P-388 lymphocytic leukemia in mice. A note-worthy vehicle-dependence of the testing results is reported. In the light of this vehicle-dependence, the re-examination of other anthraquinone derivatives is recommended.

Aloe↗