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[Research on intestinal parasitic diseases in dogs of the city of Rome].

A survey on the diffusion of intestinal parasites of dogs in the town of Rome. The results of a survey on the diffusion of cestodes and nematodes in a hundred dogs in Rome are reported. The dogs were subjected to fecal examinations --- using both the flottation method and the McMaster method -- and to the post-mortem examination of the intestine. At post-mortem examination 25 dogs were found parasitized by one or more species of nematodes, 19 by one or more species of cestodes and 12 both by cestodes and nematodes for a total of 56 animals parasitized. The parasites were identifed with the following frequency: Dipylidium caninum 28 per cent, Toxocara canis 17 per cent, Uncinaria stenocephala 15 per cent, Trichuris vulpis 10 per cent, Toxascaris leonina 9 per cent, Taenia pisiformis 4 per cent, Echinococcus granulosus 2 per cent, Ancylostoma caninum, T. hydatigena and Mesocestoides lineatus 1 per cent each. The most frequent parasite found in stray dogs was U. stenocephala (33.3 per cent) while among the dogs with owners the most frequent one was D. caninum (31.8 per cent) which was also identified most frequently in dogs over a year of age (31.1 per cent). The dogs under one year of age were more often affected by T. canis (43.7 per cent). In the paper a review of similar Italian surveys is also given.

Animals

Total mercury levels in whole blood, hair and fingernails for a population group from Rome and its surroundings.

Whole blood, hair and fingernails of 80 representative subjects from the Province of Rome were analysed for total mercury. The mean value for whole blood was 0.020 mg/kg, for hair 0.51 mg/kg and for nails 1.08 mg/kg. Correlations were found (except for hair) between mercury levels and the number of fish meals, mercury amalgam dental fillings and residence (urban or rural) of the subjects examined. The levels found in hair appear to be influenced by external and individual pollution factors and thus unsuitable for any direct determination of the distribution in other organs of the human body.

Adult

Excess mortality from influenza in a large urban population, Rome, Italy, 1956--76.

Influenza activity was studied in the Rome population from 1956 to 1976 by analysis of mortality from respiratory causes and from all causes. During cold weather months, type A influenza virus was associated, as a rule, with epidemic excess deaths at two year intervals while type B virus was prevalent twice during isolation data were also compared with epidemic excess mortality during four consecutive years. The evidence obtained indicated that influenza virus isolation alone does not represent a reliable index of epidemic influenza activity in this population. The proportion of deaths attributed to respiratory causes consistently increased in every epidemic, the most pronounced increases occurring during large epidemics. The break-down by age of deaths from respiratory causes in the course of two epidemic periods showed that the percentage distribution of deaths was essentially the same as in non-epidemic periods. This evidence indicates that the same factors influencing the age-related distribution of mortality from respiratory causes during non-epidemic periods, probably affect the fatal outcome of influenza during epidemics.

Absenteeism

Prevalence in the Rome healthy population of antibodies to a human Polyoma - virus (BK - strain).

A serological study of determine the prevalence of infections caused by human Polyoma-virus (BK strain) among the healthy population of Rome has been performed. Such virus was originally isolated from a patient undergoing a kidney transplantation, and later found in patients undergoing immunosuppressive therapy. Previous serological studies showed high incidences of infections, caused by this virus, in human populations. Other viruses, antigenically related, were found in patients suffering from progressive multifocal leukoencephalopathy. Serum samples coming from 482 healthy subjects classified by age and 100 cord blood serum samples were analyzed for antibody titers using haemoagglutination-inhibition and complement fixation tests. High incidence of infection caused by BK virus in the Roman population was found: specifically the haeomagglutination-inhibition test resulted positive in 65.2% of the samples. A remarkable similar trend between the results obtained with both the techniques was observed, although differences in antibody serum levels were present. The infections, which are not transmitted during the intrauterine life, are first noted at about two years of age. The Authors finally briefly discuss the possible epidemiological meaning of the spreading of this infection.

Adolescent

[New measurements of noise from road traffic in Rome carried out during 24 hours (author's transl)].

A new series of noise measurements in 10 points of the central zone in Rome, corresponding to residential areas with commercial activity, to parks, to hospitals, and to a subway, have been carried out. Investigation has been protracted during 24 hours and each measure has lasted 20 minutes. For the survey a mobile acoustic unity of the Environmental Hygiene Laboratory, Department of Sanitary Engineering, of Istituto Superiore di Sanità has been employed. The unity is fitted with instruments for statistical analysis of noise in connection with a minicomputer. The used program has allowed to calculate L1, L10, L50, L90, standard deviation, Leq, LNP, TNI. On the basis of such measurements Leq 24, Ldn, CNEL, have been calculated. Collected data have been compared with limits of stated rules and with noise levels measured in other seven Italian towns.

Automobiles

[Serological studies of influenza viruses in a sample of the population of Rome].

Haemagglutination inhibiting antibodies (H.I.A.) to influenza viruses A/Victoria/3/75, A/Victoria/112/76, B/Hong Kong/8/73 and A/New Jersey/8/76 were titrated in 1110 serum specimens collected in Rome in the period between March-May 1977 and obtained from subjects 0-60 years old. The H.I.A. protective level (greater than or equal to 1 : 40) found in 21.7% of the sera against A/Victoria/3/75 is such that it does not avoid a possible diffusion of this strain in the successive epidemic season. Moreover this finding suggests that there will be probably no antigenic change (4) in the same period. The age group 0-20 showed the higher titer H.I.A. Low protective levels were found against the virus A/Victoria/112/76 and B/Hong Kong/8/73, while the H.I.A. to virus A/New Jersey/8/76 showed a percentage of protective level increasing with the age.

Adolescent

[The estimated risk of coronary heart disease in four working population groups: the Rome Project of Coronary Heart Disease Prevention (author's transl)].

Within four middle-aged population groups enrolled in the Rome Project of Coronary Heart Disease Prevention, a theoretic estimation of coronary heart disease (CHD) incidence in 5 years has been made on the basis of some risk factors (age, systolic blood pressure, serum cholesterol, smoking habit, physical activity at work, body mass index), employing four different solutions of the multiple longistic function (MLF) derived from previous population studies and a simple risk score adopted by the WHO European Collaborative Group to which this study belongs. The use of different MLF solutions provides rather different levels of estimated incidence, but the ranking and the relative risk between population groups are substancially constant and little dependent on the different solutions. Moreover, an acceptable similarity has been found in terms of estimated risk between the pool of the treatment and that of the control population groups (ratio between 0.97 and 1.09). A reasonable hypothesis indicates that in the absence of preventive action the annual incidence of severe CHD (hard criteria) should be around 6 per 1,000. The estimation of the relative risk within single population groups allows to identify strata of people with different risk, which suggests, again in the absence of any preventive action, a concentration of 25-30% of all new cases of disease in a 10% of the population and about 40-45% in a 20% of the same.

Adult

[Investigation of drug users reported to the juvenile court of Rome].

After illustrating the new set of rules in matter of stupefacient and psychotropic drugs, introduced in Italy on December 1975, and the duties assigned by the law to the judicial power, the findings are set forth here of an investigation carried out on 40 youths whose addiction to the use of drugs had been reported to the juvenile court of Rome up to April 30, 1977. Anamnestic, social, judicial and clinical data on such subjects were obtained. Even with the obvious reservations resulting from the extremely small sample, some findings are observed that appear to be significant: a considerable portion of the minors addicted to the use of drugs was the recipient of other interventions by the juvenile court in the civil, administrative and criminal sphere; for the males, the prevailing anamnestetic and social data correspond to the characteristics of the other subjects, with whom the court usually deals at the "re-educational" or criminal level, while, with regard to females, the picture is remarkably different. The use of heroin seems to be wide-spread among the males, where also prevail previous hospitalizations caused by the use of drugs. The Authors advocate a new and more extensive verification, to be carried out after a period of time.

Adolescent

On the Road to ROME: Defining Tissue-Liquid Concordance in Precision Oncology.

A growing body of evidence has established liquid biopsy as a promising, noninvasive platform for genomic profiling. In this commentary, we build on findings from the multicenter, randomized phase II ROME trial and interrogate the challenges and opportunities of tissue-liquid profiling concordance in improving personalized cancer treatment and survival outcomes. See related article by Botticelli et al., p. 45.

Humans

[The experience in cardiac pacing at the Cardiology Department of St. Camillo Hospital (Rome) (author's transl)].

The experience of the Cardiac Electrostimulation Center of S. Camillo Hospital in Rome on 1503 patients treated with permanent pacemakers for an 11 year period is referred. The Authors analyze the increase of the activity of the Center during these years and some events that caused it. 94.5% of the patients were more than 50 years old; the dominant pathology has been ischemic and idiopathic cardiopathy, which together include 94.7% of the totality. The indication to the implant has been A-V block in 70% of the patients; intraventricular block in 20%; sick sinus syndrome in 10%. In the last years the prophylactic indication has increased (from 0.4% to 4.4%). 2459 pacemakers have been used, of which 79.5% was QRS-inhibit. The mercury prosthesis have been progressively substituted with the lithium ones. 1642 catheters (implant and reimplant) have been used; principally endocardic (95%) and monopolar (85%). The substitution of the catheter has been necessary in 9% of the totality; in 2.6% of the endocardic and in 15.9% of the epimyocardic. Among 50 electrodes, after a period of observation of about 7.7 years, 36 are still in function. The percentage of the complications has been 17.1%; the most important complications have been: dislocation (6%), microdislocation (1.5%), late high threshold (2.1%), failure of catheter (1.2%), generator malfunction (2.3%). The total mortality has been 15.4%; 0.2% caused by deficit of the implant; 2% sudden deaths and 13.2% not depending from the implant; 243 patients (16%) are not to be found. The frequency of out-patients controls has decreased in the last 2 years (from 3.8 controls per years to 1.8).

Aged

Drinkers and alcoholics in ancient Rome.

The history of wine making and wine drinking by the ancient Romans from earliest times to the fall of the Empire is reviewed. The drinking patterns as reflected in the works of contemporary authors indicate five periods of wine use and attitudes toward drinking.

Agriculture