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At least 19 recordsLinked to original sources

Surgical pathology of intramedullary spinal cord neoplasms.

The surgical pathology of intramedullary spinal cord neoplasms is most accurately based on radical resection specimens rather than on small biopsies, which may be highly misleading. A review of the neuropathology files at NYU Medical Center revealed 294 surgical specimens of intramedullary cord lesions examined between January 1, 1991 and December 31, 1998. Of these 117 were from children (age less than 21 years) and 177 were from adults (21 and over). While most types of central nervous system tumors known to occur in the brain also occur in the spinal cord, the different proportions of these tumors by histologic type, and the differences in the proportions of tumor types in children compared to adults, are both significant. In adults ependymomas are the predominant tumor type (93 total) while in children astrocytomas and mixed neuronal-glial tumors are virtually equally common and outnumber ependymomas. In this period no cord Primitive Neuroectodermal Tumors were identified. Among the astrocytic neoplasms and other gliomas, high grade tumors were distinctly uncommon in children and only slightly more common in adults, in sharp contrast with the brain, where the majority of adult intra-axial tumors are high grade.

Adult↗

Vascular malformations presenting as spinal cord neoplasms: case report.

Three cases of adult patients with subacute courses of progressive caudal spinal cord disease are presented. Computed tomography, magnetic resonance imaging, and myelographic studies were interpreted preoperatively as representing a spinal cord neoplasm in each case. No evidence of enlarged or abnormal surface vessels was observed by neuroimaging or intraoperatively. Biopsy specimens from each spinal cord lesion showed the typical histopathological features of a spinal vascular malformation. We conclude that vascular malformations of the caudal spinal cord can appear as isolated intramedullary lesions with apparently normal surface vessels and that these lesions may be difficult to distinguish from spinal cord neoplasms.

Aged↗

Cervical spinal cord neoplasm in a patient with an implanted cervical spinal cord stimulator: the controversial role of magnetic resonance imaging.

OBJECTIVE: To discuss the diagnostic relevance and safety concerns of performing magnetic resonance imaging (MRI) in the presence of an implanted spinal cord stimulator (SCS). CASE REPORT: A 39-year old man with CRPS I and major depression fell and fractured his humerus. A cervical SCS had been placed several years earlier. After the fall, he developed progressive lower extremity weakness. Eventually, he became wheelchair dependent and required assistance with transfers. These symptoms were attributed to CRPS and deconditioning. He was admitted to an inpatient rehabilitation unit for functional restoration. At presentation, he reported developing neck and upper thoracic pain, which started several months before the fall - a pain that was distinct from his total body pain. A contrast-enhanced CT scan of the neck was normal, except for the spinal cord stimulator induced artifact. Our pain service was consulted. After performing a neurological exam, cervical myelopathy was suspected. An MRI of the spine demonstrated a mass compressing the cervical spinal cord. The patient tolerated the MRI, despite the presence of a neurostimulator. The mass was identified as an extramedullary, intradural schwannoma and was completely excised during surgery. The patient made a profound neurological recovery. CONCLUSION: The diagnostic value of MRI may outweigh the potential dangers of using this imaging modality when a patient with a neurostimulation device presents with a new-onset neurological deficit. Thorough informed consent and close physician monitoring of these patients during the MRI is imperative.

Journal Article↗

Hanging head sign as a presenting feature of spinal cord neoplasms: a report of four cases.

A series of four patients presented with a common but unique finding: inability to hold the head in an upright position. Each complained of pain with attempts at passive extension of the neck. All subsequently were diagnosed with spinal cord neoplasms. The literature indicates that the more classic symptoms of spinal cord tumors are often slow to develop and exist for months before being accurately diagnosed. The "hanging head sign" may provide an earlier diagnosis of spinal cord lesions.

Astrocytoma↗

[Rehabilitative treatment of patients with primary and secondary spinal cord neoplasms].

The Authors present their studies concerning rehabilitation treatment in primary and secondary spinal cord tumors. They examine the problems inherent in this complex pathology. Rehabilitation was initiated in the acute phase of the illness with the aim of preventing secondary and tertiary damage that could jeopardize successive functional recuperation. The Authors believe that rehabilitation treatment, when used early enough, improves the day life for patients with spinal cord tumors.

Activities of Daily Living↗

[Effectiveness of surgical treatment in metastases of spinal cord neoplasms: on the basis of the authors' own material].

The authors present 11 patients operated on for metastatic tumours of the vertebral canal. The main symptom was pain lasting for from 3 weeks to 8 months prior to the development of spinal cord compression. The primary focus was diagnosed and treated primarily surgically in only 2 patients. In all cases laminectomy was done for removal of the epidural or intravertebral body part of the tumour and in 3 patients posterior spondylodesis was done additionally. The fate of 3 patients is unknown. Three patients died. The results of the treatment of 5 patients were assessed from 3 to 40 months after operation. The authors review in the light of the pertinent literature the modern methods of management which depend mainly on the location of the tumour.

Adult↗

[Spinal deformations as a cause for the clinical signs of spinal cord neoplasm].

An attempt was made to explain the unusual clinical manifestations at the example of an observation of a spinal-marrow tumor, which had the neurological lesion symptoms only below the upper-thoracic level. Scoliosis with a minor spinal deformation at the level of the fourth thoracic vertebra was a tumor symptom. It is suggested that the spinal scoliosis, having a mechanical impact on the spinal marrow and on its provision with blood in the minor-deformation location, was the reason of impaired sensitivity and movements, which is indicative of the spinal-marrow lesion not only in the mentioned locations but also in the total length of tumor localization. Since scoliosis can be, for some time, a single sign of the spinal-marrow lesion, the authors believe it advisable to make the magnetic-resonance therapy (MRT) in all patients with persistent scoliosis for the purpose of an early detection of a spinal-marrow neoplasm, thus, ensuring better treatment results.

Adolescent↗