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Results for “STAPHYLOCOCCAL TOXOID”

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At least 19 recordsLinked to original sources
PubMed1981

[Experimental study of the possibility of passage of staphylococcal toxoid from mother to fetus].

After the immunization of pregnant rats with purified adsorbed staphylococcal toxoid the antigen could be detected 2-48 hours later in the parenchymatous organs (the liver, the spleen), but not in the blood serum and the amniotic fluid. The rats immunized at an early period of pregnancy showed the presence of the antigen in their placenta and fetuses, while after the immunization at a late period of pregnancy the antigen could be only seldom detected in the placenta and practically never in the fetuses. There are grounds to believe that staphylococcal toxoid does not pass from the mother to the fetus through the completely formed placenta.

Animals↗
PubMed1980

[Immunoleukolysis test results in women immunized with staphylococcal toxoid].

The results of the immunoleukolysis test in 699 women on the 32nd week of pregnancy are presented. Of these, 48 women were examined 1 month and 6 months after the third injection. In this test staphylococcal allergen and E. coli allergen were used. Staphylococcal toxoid was found to have desensitizing action in persons with enhanced initial allergic state. The authors conclude that the immunoleukolysis test may ensure differential approach to the immunization of pregnant women with staphylococcal toxoid.

Allergens↗
PubMedDate not supplied

[Clinical and immunological changes in atopic dermatitis patients treated with purified staphylococcal toxoid].

32 patients with atopic dermatitis (AD), complicated by pyoderma, were treated with purified staphylococcal toxoid (PST). Changes in clinical and laboratory characteristics in the course of treatment were evaluated. PST was shown to produce a satisfactory therapeutic effect, arresting the symptoms of local staphylococcal infection. An increase in the levels of alpha- and gamma-interferons and decreased content of CD25+ lymphocytes were found. Thus prospects appear for using this preparation as an interferon inductor, as well a for the immunotherapy of AD patients sensitized to Staphylococcus aureus.

Adolescent↗
PubMedDate not supplied

[Correction of immune response using purified staphylococcal toxoid and likopid in the secondary immunodeficiency induced by Coxsackie virus B3].

The action of immunomodulators, purified staphylococcal toxoid (PST) and lycopid, on secondary immunodeficiency state developing during infection caused by Coxsackie virus B3 was studied. This defect was manifested by delayed hypersensitivity to sheep red blood cells (SRBC) and the suppression of neutralizing antibodies to poliomyelitis virus. Depending on the scheme of the experiment, PST normalized the defects of immune response to SRBC or poliovirus, increased suppression or showed no activity. Lycopid corrected the defects of humoral response to SRBC. The combination of PST and lycopid was found to produce no increase of suppression. The suggestion was made on the expediency of combination of two (and probably more) immunomodulators for increasing the efficiency of correction of secondary immunodeficiency.

Acetylmuramyl-Alanyl-Isoglutamine↗
PubMedDate not supplied

[Effect of purified staphylococcal toxoid preparation on the in vitro production of interferon by leukocytes from patients with atopic dermatitis].

The impact of purified staphylococcal toxoid (PST) on the in vitro production of interferon (IFN) by blood leukocytes was evaluated. PST was found to produce a stimulating effect on the production of alpha-IFN in patients with atopic dermatitis (AD): in 88% of cases a two-fivefold increase in IFN production was observed in AD patients in comparison with healthy donors. In addition, the incubation of leukocytes obtained from atopic and nonatopic patients with PST was shown to stimulate the production of gamma-IFN by these leukocytes fivefold, on the average. These results give theoretical basis for use of PST (as an inducer of endogenic IFN) for AD patients treatment.

Cells, Cultured↗