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Results for “SURFACE ACTIVE SUBSTANCES”

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At least 19 recordsLinked to original sources
PubMed1993

Effect of surface-active substance on nasal mucociliary clearance time: a comparison of saccharin clearance time before and after the use of surface-active substance.

Mucociliary clearance measured by saccharin clearance time is depending on ciliary function and on the physiological characteristics of mucus. The aim of this study was to determine whether the application of surface-active substances changed the mucociliary transport time. Twenty healthy persons were manually sprayed with surface-active substance in one of their nose cavities. The saccharin clearance time was measured before spraying and statistically compared with saccharin clearance time after spraying. Saccharin clearance time was significantly shortened immediately after spraying with surface-active substances. This difference was not found 2 h later. Our assay indicates that surfactant increases the rate of mucociliary transport in the upper respiratory tract.

Adult↗
PubMed1977

[Intensification of the action of antibiotics with cationic surface-active substances].

The antimicrobial effect of cationic surface-active substances, such as cetylpyridinyi chloride, alkylmethylbenzylammonium chloride ("roccal" and "catamine AB") and chlorhexidine was studied in vitro. The above compounds had a high bactericidal activity against poly-resistant staphylococcal strains. In non-bactericidal concentrations they significantly increased the efficacy of antibiotcs with different modes of action, i.e. penicillins, tetracyclines, amino-glycosides, macrolides. The effect of the cationic surface-active substances increasing the antibiotic activity against staphylococci did not depend on the resistance type, i.e. chromosomal or extrachromosomal. This was mainly associated with impairement of the function of the bacterial cytoplasmic membrane by these compounds. The cationic surface-active compounds were poor inhibitors of the specific enzyme of Bac. licheninformis 749/C, i.e. penicillinase. A marked inhibition of the enzyme was observed only at concentrations above the bactericidal ones and those damaging the cell membrane of staphylococci.

Anti-Bacterial Agents↗
PubMed1978

[Increase in tetracycline activity by using surface-active substances].

The antimicrobial effect of cationic and anionic surface-active substances, i.e. catamine AB and sulphonol NP-3 respectively was studied in vitro with respect to gramnegative bacteria. In non-bactericidal concentrations catamine AB significantly increased the efficacy of tetracyclines, while the anionic compound had no such effect. The increase in the tetracycline activity was due to the antibiotic increased absorption (14C-oxytetracycline as an example) on the treatment of gramnegative bacteria with catamine AB and staphylococci with catamine AB and sulphonol NP-3, which was mainly associated with impairement of the cell membrane permeability by the surface-active substances.

Drug Resistance, Microbial↗
PubMed2005

Influence of surface active substances on bubble motion and collision with various interfaces.

Bubble motion as a function of distance from a point of its detachment and phenomena occurring during the bubble approach and collision with liquid/gas and liquid/solid interfaces in pure water and solutions of various surface active substances are described and discussed. It is showed that presence of surface active substance has a profound influence on values of the terminal velocity and profiles of the local velocity. At low solutions concentrations there are three distinct stages in the bubble motion: (i) a rapid acceleration, (ii) a maximum velocity value followed by its monotonic decrease, and (iii) attainment of the terminal velocity, while at high concentrations (and in pure water) there are only stages (i) and (iii). It is showed that the bubble terminal velocity decreases rapidly at low surfactant concentration, but there can be found some characteristic concentrations (adsorption coverage's) above which the velocity almost stopped to decrease. Immobilization of the bubble surface resulting from adsorption of the surface active substances (surface tension gradients inducement) causes over twofold lowering of the bubble velocity. Presence of the maximum on the local velocity profiles is an indication that a stationary non-uniform distribution of adsorption coverage (needed for immobilization the bubble interface) was not established there. When the rising bubble arrives at liquid/gas interface or liquid/solid interface there can be formed either foam or wetting film or three-phase contact (TPC). It is showed that prior to the foam and/or wetting film formation the bubble colliding with the interfaces can bounce backward and simultaneously its shape pulsates rapidly with a frequency over 1000 Hz. It is rather unexpected that even in the case of the free surface the bubble's shape and consequently its surface area can vary so rapidly. It shows straightforward that on such a rapidly distorted interface the adsorption coverage can be very different from that at equilibrium. This fact should be taken into account more appropriately in the discussion of the mechanism of formation and stabilization of various dispersed systems (e.g. foams, emulsions). Bubble collision with solids and formation of the three-phase contact is a necessary condition for flotation separation. It is rather common understanding that immediate attachment should occur in the case of hydrophobic surface, while there should be no attachment in the case of the hydrophilic ones. It is reported that even in the case of such hydrophobic solid surface as Teflon, the bubble attachment did not need to occur at first collision and in distilled water the bubble can bounce a few times without attachment. Presence of frother facilitates the bubble attachment to hydrophobic solid surface. Time scale of the TPC formation is very short, of an order of single ms. It was observed that presence of a micro-bubble at the solid surface facilitated drastically an attachment of the colliding bubble. Roughness of Teflon surface increases probability of the bubble attachment-most probably-as a result of higher probability of micro- and/or nano-bubbles presence at the solid surface.

Adsorption↗
PubMed1989

[Hygienic problems in irrigating agricultural lands with sewage containing surface-active substances].

Due to wide production and use of surface-active substances (SAS)-detergents in various branches of economy, they became spread chemical factors of environment. A scheme was worked out of possible migration of SAS in environmental objects in conditions of irrigation of agricultural land by sewage waters. It is suggested that detailed studies should be directed with the purpose of reducing of contamination of human environment.

Agriculture↗
PubMed1992

[The toxicological-hygienic characteristics of surface-active substances used in the technological processes of the oil-producing industry].

The authors suggest two stages of ecological and hygienic evaluation of surface active substances widely used in oil extraction. Stage 1. Toxicological-hygienic evaluation of these substances. Stage 2. Ecological-hygienic aspects of surface active substances (migration into soil, phytotoxicity, effect on the water quality and oth.). It was established at stage 1 that proxanol, proxamin, diproxamin are compounds of minor hazard (class 4 hazard). These substances belong to local skin-irritating substances. Proxanol produces skin-resorptive effects which is confirmed by clinical signs of intoxication, reduction of weight of the experimental animals.

Amines↗
PubMed1998

[Cytotoxic properties of pancreatic ribonuclease, modified by the surface active substance oxanol KD-6].

Pancreatic RNase modified by the surface active substance oxanole KD-6 (OxRNase) was studied in respect to its cytotoxic action on cells. The studies included in vitro and in vivo tests with intravital staining of the cells by neutral red and the 3H uridine label, as well as the test with the preparation action on fusion of lysosomes and phagosomes. It was shown that in all the tests the hydrophobised RNase had a higher cytotoxic action versus the native enzyme. The analysis of the experimental data suggested that the cytotoxicity of the hydrophobised RNase was due to its action on the cell membrane structures including the lysosome membranes.

Animals↗
PubMed1989

[Directed screening of bacteria--destructive agents of surface-active substances].

A procedure for detection of bacteria destructing cationic surface active substances (CSAS) was developed. The procedure is based on changing colour of pyrocatechin violet, an organic dye from geen-blue in the presence of a CSAS to red-brown in its absence. After application of pyrocatechin violet to bacterial macrocolonies grown on a synthetic medium with a CSAS as the only source of C red-brown zones developed around the colonies which was probably indicative of the CSAS biodestruction. 55 strains of bacteria destructing undecylpyridinium bromide, a CSAS were isolated from water of sewage purification plants. The study of their spectrum with respect to CSASs of different chemical structure revealed 6 bacterial strains capable of destructing all the nine test preparations. It was shown that biodestruction of the CSASs was associated with the long carbon chain and depended on the presence of the substitute in the aromatic ring and branching in the side chain. Therefore, the procedure provides screening of microbes destructing CSASs and may be used for rapid determination of biodestruction of CSASs with different chemical structures.

Bacteriological Techniques↗
PubMed2001

[Analysis of surface-active substances in Sapindus mukurossi by high performance liquid chromatography-mass spectrometry].

A high performance liquid chromatography-atmospheric pressure ionization mass spectrometry method has been developed for the analysis of surface-active substances (hederagenin saponins and sesquiterpene oligoglycosides) in the extracts of the pericarp of Sapindus mukurossi. The method consists of the separation of surface-active substances using C18 HPLC column, followed by detection using a diode-array detector at 210 nm and then on-line mass spectrometry. Hederagenin saponins and sesquiterpene oligoglycosides were characterized as [M - H]- or [M + Na]+. Based on the relative molecular mass, established by mass spectrometry and the structure induced by in-source CID technology, three components that had not been reported in Sapindus mukurossi before were identified. Several surface-active substances were obtained by means of semi-preparative HPLC. Their structures were further confirmed by NMR spectrometry as mukurozi-saponin Y2, mukurozi-saponin X, mukurozioside I a and mukurozioside II a.

Chromatography, High Pressure Liquid↗
PubMed1991

[Hygienic significance of surface-active substances in the conditions of soil contamination with chemical substances].

Urgent problems of the interaction of surface-active substances (SAS) with other ingredients under the conditions of chemical soil pollution are discussed, in particular, under the conditions of irrigation of agricultural fields with treated municipal sewage containing detergents. Before the beginning of the irrigation season the content of anion SAS in the arable layer of the soil is 2.02-2.66 mg/kg. In the middle of the vegetation period the quantity of detergents is increased 3-4 times fold. The authors suppose, that SAS may influence translocation of heavy metals from soil into plants. However, this question should be studied more carefully in the conditions of field experience with various SAS concentrations in soil.

Agriculture↗
PubMedDate not supplied

[The ecological and hygienic aspects of the use of surface-active substances in oil-producing regions of Ukraine].

Use of surface-active substances (SAS) in the oil-extracting regions of the Ukraine should consider the fact that this is a rather small territory, densely populated, with environmental water and soil problems, significant contamination of several areas by pesticides, mineral fertilizers and complicated by the Chernobyl accidents sequels. SAS may influence the ecological-hygienic balance of the environment, they may enhance migration of many ingredients, increase their toxicity. The authors propose several measures aimed at improving the quality of preventive and actual state inspection over the oil enterprises.

Accidents, Occupational↗
PubMedDate not supplied

[The determination of the water-migration index of the harmfulness of a complex of pollutants: the anionic surface-active substance PO-1D, hexachlorocyclohexane and ammonium nitrate].

Some aspects are studied of migration of the complex of priority soil contaminants anionic detergents, hexachlorocyclohexane (HCCH) and nitrogenous fertilizers. The anionic surface-active substance [symbol: see text] favours migratory properties of nitrates, HCCH. Permissible load of anionic surface-active substances on the black earth soil that comes up to 17 kg/ha is validated.

Fertilizers↗
PubMed1986

[Effect of cationic polymers and surface-active substances on bacterial resistance to kanamycin].

The effect of cationic polymers and surface active substances (SAS) on sensitivity of Klebsiella aerogenes 600, Escherichia coli 154 and Proteus vulgaris 7470 to kanamycin was studied. A decrease in the resistance of the above organisms to kanamycin on its use in combination with cationic polymers and SAS was observed. It was shown that such substances inhibited the activity of the enzymes inactivating kanamycin. Their effect was suggested to be due to changes in the lipid surrounding of the enzymes.

Bacteria↗