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[Choice of a scleroplasty method in progressive myopia in children].

Dynamic analysis of the results of sclera-fortifying interventions (scleroplasty and sclera-fortifying injection) in children aged 8 to 12 has demonstrated that in many cases myopia stabilized but temporarily after sclera fortification in children with progressive myopia. Repeated sclera-fortifying interventions reduced the rate of postoperative myopia progress approximately twofold, the myopia stabilization period lasting for 1 to 2 years; in some cases myopia progress ceased after a repeated intervention. In 67% of patients myopia on the second eye did not progress for 6 months after sclera-fortifying injection and for a year after scleroplasty on the first eye. Sclera fortification in the paired eye is advisable within these periods. Analysis of the results from the viewpoint of the general mechanisms of scleroplasty effect has lead the authors to a conclusion that sclera-fortifying therapy of children with high progressive myopia should be carried out in several stages. A system of sclera-fortifying treatment of progressive myopia has been developed, and the continuity of methods used for this purpose validated. Effects of this treatment scheme on refraction and status of the fundus oculi are estimated.

Age Factors↗

[Peripheral segments of the fundus oculi in highly myopic patients after scleroplasty].

Prolonged (3 to 9 years) follow-up of 219 patients with high rapidly progressing myopia, treated with scleroplasty, has demonstrated an inhibiting effect of this surgery on the development and progress of peripheral vitreochorioretinal dystrophies: a negative time course on the fundus oculi periphery of the operated on eye was observed in 21.5 percent of patients and that of the intact eye in 35.1 percent of patients. Scleroplasty, carried out at the age of 9-11 and 15-17, was found the most effective from the viewpoint of preventing the peripheral vitreochorioretinal dystrophies. Reduced incidence of such dystrophies on the operated on eyes may be explained by the favorable effect of surgery, i.e. scleral distension arrest or delay, improved hemodynamics and trophics of ocular tissues. The results helped define the indications to scleroplasty with due regard for the patient's age and fundus oculi status.

Adolescent↗

[Long-term results after perforating corneo-scleroplasty in a case of acute unilateral superior pellucid marginal corneal degeneration].

PURPOSE: This case report shows the long-term results after perforating corneo-scleroplasty in a rare case of superior pellucid marginal corneal degeneration with acute hydrops due to rupture of Descemet's membrane. PATIENT: In the left cornea of a 20-year-old patient with peripheral stromal thinning from 9 to 3 o'clock a rupture in Descemet's membrane occurred followed by lamellar splitting of the mid-stromal region. Due to the decrease in visual acuity and pain from corneal edema a surgical treatment was performed consisting of a perforating/lamellar corneo-scleroplasty protecting the anterior chamber angle. RESULTS: The status has remained stable for 17 years after surgery with nearly clear graft, best corrected visual acuity of 0.8 and no signs of recurrence or progression of the disease. Central astigmatism is regular, the endothelial cell count is 1250/mm2 in the central cornea, the central corneal thickness is 540 microm and only a mild vascularised superficial pannus and slight opacities in the predescemetal layer of the graft are found. There are no anterior synechia. On the right eye visual acuity is 0.8 due to slight amblyopia. There are no corneal changes which would indicate bilaterality of the disease. CONCLUSIONS: Our findings must be interpreted as an atypically localised superior pellucid marginal corneal degeneration with rupture of Descemet's membrane followed by acute corneal hydrops. When reduction of visual acuity or pain occurs a surgical treatment by perforating/lamellar corneo-scleroplasty can be performed stopping the progression of the disease and achieving a stable optical rehabilitation and absence of pain even after decades.

Adult↗

[Scleroplasty surgery. II. Results in adults].

The authors give an account of the results assembled in 181 patients (350 eyes) where scleroplasty in Pivovarov's modification was performed. 81.4% of the operations were indicated in myopia gravis, 91% in myopia progressiva and 5.1% in combination of myopia gravis and cataract. Of four implantation materials used the irradiated human sclera proved best. Scleroplastic operations had a favourable effect on the subsequent course of myopia gravis and myopia progressiva (followed up to four years). In both these diagnoses during the postoperative period a statistically significant improvement of visual acuity was observed, while the correction changed only slightly. Scleroplasties are a suitable surgical procedure in adults who suffer from progressing or severe myopia and give them real hope of preservation of visual functions.

Adult↗

[Retrospective evaluation of eyes with high progressive myopia in children and youth ten years after Snyder and Thompson's scleroplasty].

PURPOSE: Of the study was, to assess the safety and efficiency of scleral reinforcement after Snyder and Thompson surgery. MATERIAL AND METHODS: The scleroplasty was performed on 129 eyes of 75 children with progressive myopia from 6 to 10 years of age. The control study group included 40 eyes of 25 children with similar age, mean eyeball axial length and refraction. In the control study group scleroplasty was not performed. The main indication criteria for surgery included: severe myopia more than -6.0 D, and the increase in refraction error more than -1.0 D per year. We evaluated the eyeball axial length in all subjects, before time of surgery and ten years after surgery, using Ultrasound Alcon Imaging System. The visual acuity, tonometry, visual field were evaluated as well. RESULTS: In the study group the mean eyeball axial length measured before surgery was 25.95 mm +/- 0.62 mm. Ten years after surgery the length of the eyeball was 26.97 mm +/- 0.64 mm. The average increase was 1.03 mm +/- 0.29 mm. In the control group, at the time when study group children were operated, the mean eyeball axial length was 25.91 mm +/- 0.48 mm, and ten years later it was 28.06 mm +/- 0.59 mm. The average increase in the eyeball length was 2.13 mm +/- 0.3 mm. There was statistically significant difference between the eyeball axial length progression in the study group and the control group, where surgery was not performed. In the study group no serious complications after surgery were reported. CONCLUSIONS: Scleral reinforcement is an effective and safe surgery, that can stabilize the progression of severe myopia in children.

Adolescent↗

[The late results of Murmamedov-Atameredova's modified scleroplasty in children].

Late results (a follow-up of 3 to 4 years) of 87 scleroplastic interventions according to Nurmamedov-Atameredova are analyzed. Scleroplasty in the authors' modification was carried out in children with progressive myopia aged 8 to 14. The technique is simple and low-traumatic. The process was stabilized in 39 (44.8%) eyes, in the rest eyes (n = 48, 55.2%) myopia still progressed after surgery with an average rate of 0.7 diopters a year; this progress was most frequent after high myopia or in children whose both parents suffered from myopia. Such scleroplasty technique is therefore not recommended for this patient population.

Adolescent↗

[Effectiveness of posterior scleroplasty in progressive myopia in children].

The authors evaluated the long-term results of posterior scleroplasty in a group 51 children (74 eyes) with progressive myopia followed up 2-4 years after surgery. Stabilization of myopia developed in the axial length of the bulbus in 78% of the children and in objective refraction in 85% patients. In 15-22% of the patients myopia progressed but only by 0.4 D per year. No serious complications were observed or after operation. The authors draw attention of ophthalmic surgeons to scleroplasty because in has a marked effect on the preventive of progressing severe myopia and thus for the long term preservation of satisfactory visual functions.

Adolescent↗

[Comparative evaluation of the results of various methods of scleroplasty in progressive myopia].

Six methods of scleroplasty are compared. A total of 476 operations on 423 eyes of 224 patients were carried out. The advantages of the technique suggested by the authors--fortification of the eyeball posterior pole with an auto-cartilage plate of the concha of the auricle 15 X 10 X 1 (1.5) mm in size--were revealed: both the immediate and late results of surgery were good, the surgery was low traumatic, no allergic reactions were recorded, the unpleasant sensations of the patients were the minimal; possible complications of scleroplasty, such as optic nerve and vorticose vein compression or perforation of thinned sclera, became less threatening.

Adolescent↗

[A combination of scleroplasty with intrascleral revascularization in myopia].

A combination of scleroplasty after Pivovarov-Pristavko with revascularization of the sclera in the author's modification was used for treatment of myopic disease with expressed dystrophic changes in the eye fundus (stages III-V). For revascularization, the Tenon's capsule is used. It is introduced and sutured in the intrascleral pocket in the superexternal quadrant of the eye ball. The operation was used in 31 patients (35 eyes). No complication was recorded. Remote observations, from 1 to 3 years, over 21 patients (23 eyes) have shown stabilization of dystrophic processes and preservation or rise of visual acuity in 21 eyes (91%). The effectiveness of the operation is explained by improved blood circulation in the eye coats on account of both scleroplasty and revascularization of the sclera by the Tenon's capsule.

Adolescent↗

[The morphological characteristics of the take of synthetic transplants following experimental scleroplasty].

The morphology of taking in of synthetic transplants after scleroplasty is studied in 24 eyes of chinchilla rabbits. Polytetrafluorethylene-based materials (composite filtration fluoroplast membrane--Teflon) and polyester jersey with reticular structure (scleracod) were used for transplantation. Study of two materials showed common processes and differences in the grafts taking in. Implants made of both materials are characterized by good biocompatibility, which prompts further investigation of their probable use in sclera-fortifying treatment of progressive myopia.

Animals↗

[The morphological changes in different grafts in scleroplasty].

In the paper experimental and morphological investigations of cadaveric aorta wall and dura mater grafting for scleroplasty are analysed. The experiments were performed of 20 chinchilla rabbit eyes. The investigations have shown the processes of aortic allotransplants replacement by recipient tissues. Histological peculiarities of the sclera structural regeneration in the conditions of the aorta and dura mater grafting have been established.

Animals↗

[Plasma-modified silicone graft for scleroplasty in progressive myopia].

Plasma-chemical modification of synthetic transplant material (proliferous silicone) intended for scleroplasty in progressive myopia was theoretically substantiated, developed in the experiment and tested in practice. This treatment was shown to enhance the biocompatibility of a graft which tightly joins the sclera through the connective tissue intergrown from the surrounding capsule into the graft. The efficacy of the proposed plasma-modified grafts in stabilizing progressive myopia in 18 patients operated on (33 eyes) aged 6 to 49 years (spherical equivalent myopia degree 3.0-28.0 D) during 3- year followup was 97%. There was an elevation of uncorrected and corrected visual acuity, are active course of the postoperative period.

Adolescent↗

[Scleroplasty surgery. I. Results in children].

The authors give an account on the results of scleroplastic operations (according Pivovarov) in 159 children (298 eyes). They describe in detail the surgical procedure, the mechanism of action of the operation, the fate of the implanted material. The most suitable material for scleroplastic operations in children is the irradiated human sclera which caused the minimal incidence of complications. Most frequently eyes with the diagnosis myopia progressiva 57.7% were operated, another large group were eyes with the diagnosis of myopia gravis -35.2%. The mean age at the time of operation was 11.3 +/- 3.3 years. In myopia progressiva the correction was three years after operation the same or lower in 53.3% of the operated patients, the vision was equal or better in 80% of the operated patients. In children with myopia progressiva who were operated at the age of 10-15 years, after three years no difference in vision was recorded as compared with the finding before operation; the correction changed on average only by 0.27 dioptres. This result is very satisfactory, as indication for operation was progression of myopia by at least 1 dioptre per year before operation. In myopia gravis the correction was three years after operation equal or lower in 68.4% of operated eyes, the vision was equal or better in 81.6% of the operated eyes. Reinforcement of the sclera--scleroplasty--is at the moment the only rational therapeutic method of progressing and severe myopia.

Adolescent↗

Scleroplasty in progressive myopia--selection of materials.

Scleroplastic surgery is known to encounter the pathogenetical agent when the progressive myopia develops. In the first part, the implemented surgical approaches as well as up-to-date surgical techniques are presented. The experimental part is reserved for the selection of material which is necessary to perform scleroplasties. Both the allogenic and xenogenic grafts have been studied for histocompatibility on 20 rabbits. Following materials were used: 2 types of collagenic sponge, native and deproteinated human sclera, modified dura mater as well as both the native and devitalized sclera from rabbits. The best results were obtained with allogenic sclera, deproteinated xenogenic sclera and collagenic sponge. The application of other materials is discussed.

Animals↗

[Long-term results of scleroplasty surgery in children].

The authors presents results of scleroplastic operations in 411 children (773 eyes) followed up to 7 years after surgery: Most frequently eyes with the diagnosis myopia progressiva (397 = 51.4%) and myopia gravis (330 = 12.7%) were operated. The mean age at the time of operation was 12.2 +/- 3.0 years myopia progressiva and 10.8 +/- 3.9 years in myopia gravis. The difference was statistically significant (p = 0.0002). The visual acuity was on average better throughout the follow-up period in both main diagnoses, as compared with initial values. The progression of myopia (subjective refraction) slowed down markedly after surgery and was 0.26 D/year in myopia progressiva and 0.23 D/year in myopia gravis. The authors recommend scleroplasty to prevent significant progression of myopia and for longterm preservation of visual functions.

Child↗

Long-term results of scleroplasty operations in children.

The authors refer results of 773 scleroplasty operations performed in 411 children, mean age was 11.3, S.D. 3.6 years. Irradiated human sclera proved to be the best material for scleral reinforcement. Mean myopia progression was 0.26 D/year in myopia progressiva and 0.23 D/year in myopia gravis. Mean visual acuity was better in all intervals after surgery (p = 0.0000 one and four years after, 0.0002 six years after in myopia progressiva, in the same intervals in myopia gravis it was 0.0009, 0.0027, 0.0002). Scleral reinforcement can positively influence myopia progression.

Child↗

[Scleroplasty results in congenital myopia].

The author analyzes late results of scleroplasty carried out in progressive congenital myopia and the relationship of these results with the initial status of the anatomo-optic elements of the eye in patients aged 7 to 22. Surgical treatment according to E. S. Avetisov and E. P. Tarutta was carried out in all the patients. The efficacy of surgery was found to directly depend on the status of the anatomo-optic elements of the eye and the patient's age.

Adolescent↗

[Scleroplasty surgery in the treatment of progressive myopia in children].

The authors evaluate the results of 257 scleroplastic operations performed in 145 children with progressive myopia in 1989-1995. The age range of the operated children was 5-17 years. The mean age at the time of operation was 10.4 +/- 3.9 years. The children were followed up for at least two years before and two years after operation. All children met the condition of progressive myopia, minimal refraction -6.0 D and progression of at least 1 D per year during the last two years before surgery. The authors investigated the axial length of the bulbus by biometry, objective and subjective refraction, the best corrected visual acuity before and after surgery. The mean progression of myopia two years after the scleroplastic operation declined to a mean value of 0.29/year. No serious complications were recorded. Scleroplasty can be considered a safe surgical method which can help to improve the unfavourable development of progressive myopia.

Adolescent↗