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At least 19 recordsLinked to original sources
PubMed1979

[Microcirculatory bed of serous membranes in rats with spontaneous genetic hypertension].

The microvasculature (MV) of serous membranes was compared in rats with spontaneous genetic hypertension (SHR) and in normotensive Wistar rats. The study showed that in hypertension MV lesions had a systemic distribution, as structural changes were present in every MV component (arterioles, precapillaries, capillaries, postcapillaries, venules, lymphatic capillaries, and postcapillaries, nerve fibers); these lesions were generalized, as similar alterations could be found in all serous membranes studied. A close resemblance observed between MV of serous membranes in SHR and in patients who died of hypertensive disease confirms the concept suggesting the existence of MV changes which were relatively specific for hypertension, along with those of the nonspecific nature. Specificity of the hypertensive process is manifested in severe vascular lesions of a peculiar type, while the nonspecific phenomena are represented by a combination of intravascular, perivascular, and minimal vascular alterations represented by a universal MV response to various stresses.

Animals↗
PubMed1975

[Morphologic changes in the lymph microcirculation of serous membranes in rheumatism and systemic lupus erythematosus].

Microcirculation consists of two elements--hemomicrocirculation and lymphomicrocirculation, the both being closely interrelated with each other. Lymphomicrocirculation was studied on the serous membranes taken from dead people who had died of rheumatism and systemic lupus erythematosus (SLE). The microcirculatory bed in the serous membranes was identified by V. V. Kupriyanov's method. The results of the studies showed that in serous membranes in rheumatism there occurred gradual emptying of lymphomicrocirculation and at the same time--compensatory-adaptive and regeneratory processes, the latter being manifested in formation of blind projections of capillaries, in broadening of the lumen. In SLE the lymphatic link actively participated in elimination of metabolism products and underwent a continuous rearrangement with formation of closed and communicant cysterns. Moreover, there was noted a new formation of lymphatic capillaries, which should be considered as a compensatory-adaptive process. Hemo- and lymphomicrocirculation elements are intimately connected due to close contacts between capillaries of the two elements of microcirculation, however, without formation of connecting fistulas. Hemo- and lymphomicrocirculation is an integrate, and under conditions of pathology there developed therein compensatory-adaptive and regenerative processes aimed at the maintenance of tissue metabolic and hemodynamic homeostasis.

Adolescent↗
PubMed1978

[Microcirculatory bed of the serous membranes in hypertension].

In hypertension, all the components are affected in the microcirculatory bed of serous membranes: arterioles, precapillaries, capillaries, postcapillaries, venules, lymph capillaries and postcapillaries. Convolution of microvessels, formation of loops, skeins, torsions along the longitudinal axis, deformation of walls (folds and angularity of the contours, multiple unilateral and bilateral protrusions and invaginations, sacciform and cylindrical microaneurisms, multiplication of venules) are observed. In the control material collected from subjects who had died of various traumas vascular changes in serous membranes are poorly manifest or absent indicating a relative specificity of the microvessel involvement in hypertension. The results of the study are in accord with known from literature descriptions of changes in the microcirculatory bed of the eye conjunctiva observed in biomicroscopy in patients with hypertension which confirms the generalized nature of MCB involvement in this disease.

Adult↗
PubMedDate not supplied

[Competitive inhibition of the fixation of various cytotropic antibodies to mast cells of the peritoneal serous membrane in the guinea pig].

The degranulating capacity of guinea pig peritoneal serous membrane mast-cells due to IgG1 and reaginic homocytotropic antibodies and heterocytotropic rabbit IgG antibody was studied, as was the interference which nonspecific immunoglobulins may produce in the fixation of antibodies. Although the capacity to degranulate mast-cells proved identical for all the antibodies studied, reagin appears to possess a greater fixation capacity for a possible cellular membrane site. The greater resistence of reagin to elimination by washing could account for this.

Animals↗
PubMed1977

[Pathomorphology of the vessels of the microcirculatory bed of the serous membranes in systemic allergic vasculitis].

The impregnation method and micropreparation were used to study the morphological changes in vessels of the microcirculatory channel of serous membranes in systemic allergic vasculites. Inflammatory and sclerotic processes in arterioles, precapillaries, capillaries, postcapillaries, and venules were found to be accompanied by regeneration changes and complicated adaptative alteration of the intact structures of the terminal vascular bed. The paper also presents morphological data reflecting decompensation processes in local lymph and blood flow.

Adolescent↗
PubMed1977

[The lymphomicrocirculatory bed of serous membranes in several human diseases].

Morphological changes in the lymphatic link of the microcirculation of serous coats were studied by the method of non-injection impregnation with silver nitrate in rheumatism, lupus erythematosus, chronic nonspecific pneumonia, pulmonary tuberculosis. There were identified 4 types of the state of lymphatic capillaries and postcapillaries, namely: functioning, dystrophized, sclerosing, and regenerating, reflecting a state of the lymphatic system at a given stage of a disease. Regeneration of lymphatic capillaries, as well as formation of lymphatic cisterns, cysts etc., the author classifies as manifestations of compensatory-adaptive processes of the organism aimed at preservation of the hemato-lymphatic balance. The hemo- and lymphocirculation functions as one integral system.

Chronic Disease↗
PubMed1975

[Cholinergic and adrenergic innervation of the microvessels of serous membranes].

The morphological substrate of double (sympathetic and parasympathetic) innervation of the vessels of the microcirculatory bed of serous coat was studied in cats. The architectonics of both components of the vasomotor innervation in the pericardium, the pleura and the peritoneum was examined by histochemical methods used for revealing the cholinergic (Koelle-Gomori) and the adrenergic (Falck-Hillarp) neutral structures. the quantitative predominance of the elements of adrenergic innervation over the cholinergic ones was revealed in the identical portions of the arterial bed. Vegetative innervation of the terminal arteries and capillaries was unsteady in character and proved to be essentially confined to single synaptic contacts arising along the course of adrenergic and cholinergic terminals. Vegetative innervation of the venous supply including the postcapillary venules and small collecting veins was extremely poor and frequently not found at all.

Acetylcholinesterase↗
PubMedDate not supplied

[Cholesterol biosynthesis in stomach and intestinal tissue of rat].

Biosynthesis of cholesterol and its precursors (metastenol, latosterol and 7-dehydrocholesterol) was studied in the mucous and serous membranes of small intestine, secretory and esophageal regions of the normal rat stomach. The content of these sterols was also determined. The intensity of sodium 2-14C-acetate incorporation into cholesterol and its precursors in the mucous membrane of the small intestine and stomach secretory region is considerably higher than into the same sterols of the serous membrane and esophageal region. Cholesterol synthesis is most intensive in the small intestine mucous membrane and stomach secretory region.

Acetates↗
PubMed1978

[Microangioarchitectonics and microtopography of the blood vessels of the human stomach].

The data of previous investigations on general principles of microarchitectonics of the human intraorganic gastric vessels have been checked. Peculiarities of branching and course of the stomach intraorganic vessels, arterio-venous anastomoses, twisted arterioles, sinusoid venules and veins confirm activity and variability of the organ's circulation at microcirculatory level. Certain slight differences in diameters and number of microvessels have been revealed in some anatomical parts of the serous membrane and submucous layer of the stomach. Maximal differences in vessel diameters of the microcirculatory bed and in number of capillaries per 1 mm2 have been revealed in the most active layers of the gastric wall--in muscular and mucous membranes. In the muscular membrane, large vessels and greater number of capillaries have been revealed in the area of the greater curvature and the pylorus. In the serous membrane in the pyloric area and in the area of the smaller curvature, microvessels have smaller diameters and the number of capillaries per square unit is less.

Adolescent↗
PubMed1978

[Morphometric findings in the microcirculatory bed of the sigmoid serosa during the fetal period in man].

During fetal life, formation and arrangement of the microcirculatory bed in the serous membrane of the sigmoid colon correspond to the growth and functioning of the latter at different stages of ontogenesis. Two periods in the development of the microcirculatory bed of the serous membrane of the sigmoid colon are revealed: the first period coincides with the first half of the fetal development when capillary growth is considerable, i.e. with the growth of metabolic part in the microcirculatory bed; the second period coincides with the second half of the fetal development when intensified growth of the sigmoid portion of the large intenstine and its transport sections in the microcirculatory bed (arterioles, precapillaries, postcapillaries, venules) are observed.

Arterioles↗
PubMed1975

[The density of the lymphatic bed of the small intestine mucosa].

The investigation was performed on 35 corpses of men, 8 corpses of cats, 7--of pigs and 5--of horses. The following methods were used: polychrome injection of arteries, veins, lymph capillaries and vessels, macro-microdissection, staining after van Gieson and with hematoxylin-eosin, impregnation with 0,25--1% solution of silver nitrate, dehydration and clearing, calculation of thickness of loops per 1 mm2 and their depth by means of ocular micrometer. The lymphatic bed of the serous membrane was established to be better developed in representatives of carnivora (cats) and omnivora (pigs), than in herbinorous horses. The monolauer capillary lymphatic network was revealed in horses while in carnivora (cats) and omnivora (pigs) the network of lymph capillaries and the bundle of lymphatic vessels were revealed. The lymphatic bed of the serous membrane was sufficiently developed in young animals. Local distinctions were established along the length and width of the small intestine, which might be explained by different functions of different portions of the gut.

Animals↗
PubMed1978

[State of the microcirculation in periarteritis nodosa based on morphological and biomicroscopic data].

The status of microcirculation in periarteritis nodosa was studied by impregnation method (serous membranes) and biomicroscopy (eyeball conjunctiva). Pathological and adaptative changes in terminal vessels were found. It is suggested that the involvement of microcirculation ways in this disease is systemic and that morphological changes in microvessels are comparable to biomicroscopic changes.

Adolescent↗
PubMedDate not supplied

Anatomical effects of sudden middle ear pressure changes.

Acute middle ear (ME) and inner ear changes following brief unilateral phasic ME pressure changes (up to +/- 6000/mm H2O) were studied in the guinea pig. Middle ear findings included perforation of the tympanic membrane, serous and serosanguinous exudate and hemorrhage of tympanic membrane and periosteal vessels. Changes were related to magnitude of applied pressure. Perforation and hemorrhage were more commonly seen with negative rather than positive pressure. Air bubbles behind the round window were seen with positive pressures. Occasional distortion, but never perforation of the round window, was noted. Hemorrhage of the scala tympani was observed with both positive and negative pressures; scala vestibuli hemorrhage was found with negative ME pressure. In some instances pressure direction and magnitude related changes were seen in the contralateral ear.

Animals↗